{"title":"Bundles \u0026 Stacks","description":"\u003cp\u003eThis collection holds every multi-item bundle we sell, from our own label and from the Muscle Market brands Yakka Strength, Thoroughbred Labs and iMuscle. A bundle is a set of separate research listings packed together at one price. That is all it is. We make no claim that the compounds in a bundle act together, complement one another or produce any result in combination; they are grouped for convenience and to save you assembling the same basket by hand. Every item is sold to adults for laboratory research only.\u003c\/p\u003e\n\u003ch2\u003eWhat this collection covers\u003c\/h2\u003e\n\u003ch3\u003eFree Muscle bundles\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/bioreactive-bundle\"\u003eBioreactive Bundle\u003c\/a\u003e: MK-777 (Acetamoren), RAD-150 (TLB-150) and NitraGlyc, the stimulant-free pre-workout food supplement, from the \u003ca href=\"\/collections\/bioreactive-series\"\u003eBioreactive Series\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/christmas-bulking-bundle\"\u003eResearch Bundle\u003c\/a\u003e: \u003ca href=\"\/collections\/mk-677\"\u003eMK-677\u003c\/a\u003e, \u003ca href=\"\/collections\/rad-140\"\u003eRAD-140\u003c\/a\u003e and \u003ca href=\"\/collections\/yk-11\"\u003eYK-11\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eYakka Strength bundles\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/yakka-strength-yakka-strength-wolverine-stack-bpc157-tb500-capsule-peptide-bundle\"\u003eWolverine Stack\u003c\/a\u003e: \u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157\u003c\/a\u003e and \u003ca href=\"\/collections\/tb-500\"\u003eTB-500\u003c\/a\u003e capsules.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/yakka-strength-yakka-strength-rad140-enclomiphene-bundle\"\u003eRAD-140 and Enclomiphene\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/yakka-strength-yakka-strength-mk677-rad140\"\u003eMK-677 and RAD-140\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/yakka-strength-yakka-strength-mk677-bpc157-tb500-capsule-bundle\"\u003eMK-677, BPC-157 and TB-500\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/yakka-strength-yakka-strength-mk677-tb500-capsule-bundle\"\u003eMK-677 and TB-500\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/yakka-strength-yakka-strength-mk677-bpc157-capsule-bundle\"\u003eMK-677 and BPC-157\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eThoroughbred Labs and iMuscle bundles\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/thoroughbred-labs-research-system-slu-pp-332-amp-5-amino-1mq-ndash-thoroughbred-labs\"\u003eThoroughbred Labs Research System\u003c\/a\u003e: \u003ca href=\"\/collections\/slu-pp-332\"\u003eSLU-PP-332\u003c\/a\u003e and \u003ca href=\"\/collections\/5-amino-1mq\"\u003e5-Amino-1MQ\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/thoroughbred-labs-research-system-bpc157-amp-tb500-capsule-ndash-thoroughbred-labs\"\u003eThoroughbred Labs Research System\u003c\/a\u003e: BPC-157 and TB-500.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/imuscle-testolon-yk11-ibutamoren\"\u003eiMuscle Testolone, YK-11 and Ibutamoren\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/imuscle-ostarine-andarine-cardarine\"\u003eiMuscle Ostarine, Andarine and Cardarine\u003c\/a\u003e, covering \u003ca href=\"\/collections\/ostarine\"\u003eOstarine\u003c\/a\u003e, \u003ca href=\"\/collections\/andarine\"\u003eAndarine\u003c\/a\u003e and \u003ca href=\"\/collections\/cardarine\"\u003eCardarine\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHow to compare a bundle with single listings\u003c\/h3\u003e\n\u003cp\u003eAdd up what the same items cost bought separately, then compare. Bundles are usually cheaper, but not always, and prices move. Check that the strength and capsule count of each item in the bundle match the single listings you are comparing, because a bundle can contain a different pack size. Then ask about batch certificates for each item, not just one. The \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e article covers the arithmetic.\u003c\/p\u003e\n\u003ch2\u003eBatch testing and certificates of analysis\u003c\/h2\u003e\n\u003cp\u003eFree Muscle-brand items in a bundle are assayed by Janoshik Analytical batch by batch, and each pack carries its own batch number; email us the numbers and we will send a certificate for each. For Yakka Strength, Thoroughbred Labs and iMuscle, a certificate is shown only where the manufacturer supplies one for the batch we hold. A generic document with no batch number is not a batch certificate. See \u003ca href=\"\/pages\/lab-tests\"\u003ehow we test\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eLegal status in the UK\u003c\/h2\u003e\n\u003cp\u003eEvery research compound in these bundles is unlicensed as a medicine (MHRA), is not an authorised food supplement and is sold to adults for laboratory research only, not for human consumption. SARMs, growth hormone secretagogues, peptides and metabolic modulators are prohibited under the WADA list. NitraGlyc, inside the Bioreactive Bundle, is a food supplement. Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e covers the wider legal picture.\u003c\/p\u003e\n\u003ch2\u003eDelivery and returns\u003c\/h2\u003e\n\u003cp\u003eFree Muscle is a UK company (FreeMuscle LTD, Scunthorpe). Every order ships free with UK tracking in plain packaging; EU delivery takes 3 to 7 working days. Orders placed before 2pm Monday to Friday are processed the same working day, and unopened items can be returned within 30 days. See \u003ca href=\"\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e. Customers must be 18 or over.\u003c\/p\u003e\n\u003ch2\u003eRelated reading\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/muscle-market-launch\"\u003eMuscle Market is live: five brands, one basket, one parcel\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/mk-677-brands-compared\"\u003eMK-677 by brand: what actually differs when the molecule is the same\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003eHow to Read a Certificate of Analysis (COA)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/sarms-vs-peptides-choosing-by-goal\"\u003eSARMs vs Peptides: Choosing by Goal\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003eRelated collections: \u003ca href=\"\/collections\/brand-yakka-strength\"\u003eYakka Strength\u003c\/a\u003e, \u003ca href=\"\/collections\/brand-thoroughbred-labs\"\u003eThoroughbred Labs\u003c\/a\u003e, \u003ca href=\"\/collections\/brand-imuscle\"\u003eiMuscle\u003c\/a\u003e, \u003ca href=\"\/collections\/brand-free-muscle\"\u003eFree Muscle\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eAll research compounds in this collection are supplied for laboratory research only. They have not been evaluated by the MHRA, EMA or FDA, are not for human consumption and are sold only to adults aged 18 and over. Nothing on this page is medical, dosing or stacking advice.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"bioreactive-bundle","title":"Bioreactive Bundle — MK-777 + RAD-150 + NitraGlyc","description":"\u003cp\u003e\u003cstrong\u003eBioreactive Bundle — MK-777 + RAD-150 + NitraGlyc. Three bottles, 180 capsules.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOne bottle each of MK-777 (a ghrelin-receptor secretagogue), RAD-150 (a SARM) and NitraGlyc (a stimulant-free pre-workout). Two of the three have no completed human efficacy trials; NitraGlyc is an ordinary sports supplement.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhy buy the bundle? Price, and nothing else.\u003c\/strong\u003e It is the same three products at a lower total than buying them separately. We are not claiming they work better together.\u003c\/p\u003e\u003cp\u003eBuying compounds together does not make them safer — each carries its own risks, set out on its own page. MK-777 and RAD-150 are \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e, and both classes are on the WADA Prohibited List.\u003c\/p\u003e\u003cp\u003eEvery batch is assayed by Janoshik Analytical, an independent laboratory. Certificates of Analysis available on request.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Not medicines or dietary supplements, not evaluated by the MHRA, EMA or FDA, not for human consumption.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":47042968584418,"sku":"10000017","price":150.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/IMG-2582.jpg?v=1766262729"},{"product_id":"imuscle-cardarine-gw501516-ligandrol","title":"iMuscle Cardarine GW-501516 + Ligandrol stack","description":"\u003cp\u003e\u003cstrong\u003eiMuscle Cardarine GW-501516 + Ligandrol\u003c\/strong\u003e is a two-compound bundle from iMuscle that pairs Cardarine (GW-501516) with LGD-4033 (Ligandrol), 60 capsules in total. iMuscle does not state the strength of either compound and we do not guess at it. The bundle simply offers both in one listing; we make no claim that the two do anything together. Supplied for laboratory research only, not for human consumption, to adults aged 18 and over.\u003c\/p\u003e\u003cp\u003eNothing here suggests they be studied or used together.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eCardarine (GW-501516)\u003c\/h3\u003e\u003cp\u003eCardarine, also written GW501516 or endurobol, is a synthetic PPAR-delta agonist developed by GlaxoSmithKline and Ligand for lipid disorders; it is not a SARM. A 2012 twelve-week human trial in 268 subjects with low HDL cholesterol recorded a rise in HDL and a fall in triglycerides, but was not designed to assess long-term safety (Olson et al., 2012). Clinical development was halted after two-year rodent carcinogenicity studies found tumours in multiple organs. Every brand we stock is on the \u003ca href=\"\/collections\/cardarine\"\u003eCardarine collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eLGD-4033 (Ligandrol)\u003c\/h3\u003e\u003cp\u003eLGD-4033, also called ligandrol or VK5211, is a non-steroidal selective androgen receptor modulator from Ligand Pharmaceuticals. In a 2013 placebo-controlled study, 76 healthy men aged 21 to 50 took LGD-4033 or placebo for 21 days. Lean body mass rose dose-dependently while fat mass did not change significantly; total testosterone, SHBG, HDL cholesterol and triglycerides fell dose-dependently, and free testosterone and FSH fell at the highest level only. Hormones and lipids returned to baseline after the study ended (Basaria et al., 2013). It was never approved. See the \u003ca href=\"\/collections\/lgd-4033\"\u003eLGD-4033 collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eHow the two compounds differ\u003c\/h3\u003e\u003cp\u003eSharing a bundle does not make the two relatives. They bind different receptors, come from different chemical families and sit in different sections of the anti-doping list.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eProperty\u003c\/th\u003e\n\u003cth\u003eCardarine\u003c\/th\u003e\n\u003cth\u003eLGD-4033\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eClass\u003c\/td\u003e\n\u003ctd\u003ePPAR-delta agonist (not a SARM)\u003c\/td\u003e\n\u003ctd\u003eSelective androgen receptor modulator\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReceptor\u003c\/td\u003e\n\u003ctd\u003ePPAR-delta, a nuclear receptor governing fatty-acid oxidation genes\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor, the receptor testosterone activates\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e317318-70-0\u003c\/td\u003e\n\u003ctd\u003e1165910-22-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and molecular weight\u003c\/td\u003e\n\u003ctd\u003eC21H18F3NO3S2, 453.5 g\/mol\u003c\/td\u003e\n\u003ctd\u003eC14H12F6N2O, 338.25 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStereocentres\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003ctd\u003eTwo, marked (2R) and (1R) in the systematic name\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublished human data\u003c\/td\u003e\n\u003ctd\u003eLipid trials in people with low HDL cholesterol\u003c\/td\u003e\n\u003ctd\u003eOne 21-day placebo-controlled study in healthy men\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWhy development stopped or stalled\u003c\/td\u003e\n\u003ctd\u003eTumours in two-year rodent studies\u003c\/td\u003e\n\u003ctd\u003eNot approved; no long-term human data published\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA section\u003c\/td\u003e\n\u003ctd\u003eS4, hormone and metabolic modulators\u003c\/td\u003e\n\u003ctd\u003eS1, anabolic agents\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eNothing summarised above is a claim about this product, and no published study has examined these compounds together.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: iMuscle\u003c\/li\u003e\n\u003cli\u003eCompounds: Cardarine (GW-501516) and LGD-4033 (Ligandrol)\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules in total across the bundle\u003c\/li\u003e\n\u003cli\u003eStrength per compound: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eBundle basis: two compounds in one listing; no combined effect is claimed\u003c\/li\u003e\n\u003cli\u003eUse: laboratory research only, not for human consumption, adults 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWith no stated strength, total milligrams per pack cannot be calculated and we do not estimate it. The single-compound iMuscle listings carry a label strength; see \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCardarine and LGD-4033 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eTwo questions come up most often about these compounds in Britain: whether they can be bought lawfully, and how one listing can be told apart from another.\u003c\/p\u003e\u003ch3\u003eThe legal position for each compound\u003c\/h3\u003e\u003cp\u003eNeither Cardarine nor LGD-4033 is a licensed medicine in the UK (MHRA) or an authorised food supplement, so neither may be sold for people to take. They are not controlled drugs under the Misuse of Drugs Act 1971 and may be sold to adults for laboratory research, the only basis for this listing. Free Muscle gives no directions for use with either. Both are on the WADA Prohibited List, Cardarine under S4 (hormone and metabolic modulators) and LGD-4033 under S1 (anabolic agents), and are banned in tested sport at all times. Background: \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eWhy the label alone settles nothing\u003c\/h3\u003e\u003cp\u003eBoth compounds in this bundle turn up in the best-known analysis of products sold online. In 2016, researchers working with anti-doping laboratory methods bought 44 products marketed as SARMs (Van Wagoner et al., 2017). LGD-4033 was one of the three SARMs they detected, in the 23 products that contained any SARM. GW501516 was among the other unapproved drugs found in 17 further products. Four products held no active compound, eleven held substances not listed, and only 18 of the 44 contained the amount their label stated. For a two-compound bundle, that means two separate claims to confirm, not one.\u003c\/p\u003e\u003ch3\u003eWhat a checkable listing shows, and how this one compares\u003c\/h3\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eA named manufacturer and a named UK seller.\u003c\/strong\u003e Met: iMuscle makes the bundle, and FreeMuscle LTD, a UK company in Scunthorpe, sells and dispatches it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated strength for each compound.\u003c\/strong\u003e Not met: iMuscle states none, so we quote none.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate for each lot held.\u003c\/strong\u003e Shown only where iMuscle supplies one for the batch we hold; see the certificate section below.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-only terms.\u003c\/strong\u003e Met: no amounts, schedules or outcome claims, adults aged 18 and over.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTraceable, discreet delivery.\u003c\/strong\u003e Met: every UK order goes free and tracked in plain packaging.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA way to send it back.\u003c\/strong\u003e Met: any unopened item can come back within 30 days, as set out on the \u003ca href=\"\/pages\/shipping\"\u003edelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003eStar ratings and forum threads record delivery experiences, not capsule contents. A longer checklist is in \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eBoth compounds are also offered as liquids and loose powders. The molecule does not change with the format; what changes is where the quantity per unit is fixed, and so what a certificate can vouch for.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsules, as here.\u003c\/strong\u003e Powder is blended and portioned into shells before sealing, so the amount is set once, at manufacture, and an assay can report it directly. The unknown is how evenly the blend was mixed, since a single assay reports an average across the capsules sampled.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquids.\u003c\/strong\u003e Sold by concentration, so every portion depends on measuring a volume accurately. A solution opened often can lose solvent and grow stronger.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePowder.\u003c\/strong\u003e Nothing is portioned in advance, so accuracy depends wholly on the balance and the person weighing.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eInjectable versions of either are sometimes listed, but no human study we can cite gave either compound by injection; the 2013 LGD-4033 study describes it as an oral compound in its title. Neither is a peptide. At 453.5 and 338.25 g\/mol they are small synthetic molecules, so the argument that digestive enzymes break down swallowed peptides does not apply to them in the same way (see \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e). For this bundle, the capsule format's main strength, a stated figure per capsule that can be checked, is absent because iMuscle states none.\u003c\/p\u003e\u003ch2\u003eEach compound compared with its most-searched alternative\u003c\/h2\u003e\u003cp\u003eA bundle has no single comparison, so each compound is set against the one it is most often searched with: \"stenabolic vs cardarine\" and \"LGD 4033 vs RAD 140\".\u003c\/p\u003e\u003ch3\u003eCardarine compared with SR9009\u003c\/h3\u003e\u003cp\u003eSR9009, sold as stenabolic, is often treated as a sister compound of Cardarine, but the resemblance is commercial, not chemical. SR9009 (C20H24ClN3O4S, CAS 1379686-30-2) binds REV-ERB alpha and beta, receptors in the circadian clock, whereas Cardarine binds PPAR-delta. SR9009 came from an academic laboratory at the Scripps Research Institute and was first described in 2012 in mouse work; it has never entered a clinical trial, so it has no human lipid data like Cardarine's and no published two-year carcinogenicity studies either. That second gap is missing information, not reassurance. Neither is licensed anywhere; WADA lists both under S4. SR9009 brands are in the \u003ca href=\"\/collections\/sr9009\"\u003eSR9009 collection\u003c\/a\u003e, with background in the \u003ca href=\"\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eLGD-4033 compared with RAD-140\u003c\/h3\u003e\u003cp\u003eRAD-140 (testolone, vosilasarm), from Radius Health, is like LGD-4033 a non-steroidal SARM that activates the androgen receptor and was never approved. Their clinical records point in different directions. LGD-4033 was given to healthy young men for three weeks with body composition and hormones among the outcomes. RAD-140's first-in-human phase 1 study enrolled 22 postmenopausal women with ER-positive, HER2-negative metastatic breast cancer to establish safety and a maximum tolerated level; raised liver enzymes (AST in 59% and ALT in 45%) were the most frequent adverse events (LoRusso et al., 2022). No trial has compared them, so claims that one is stronger rest on anecdote. WADA names both in section S1.2. RAD-140 brands are in the \u003ca href=\"\/collections\/rad-140\"\u003eRAD-140 collection\u003c\/a\u003e, and its trial is covered in \u003ca href=\"\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eiMuscle is a third-party brand, so any certificate of analysis is the manufacturer's. We show one only where iMuscle supplies it for the batch we hold; a bundle may draw on a separate batch per compound, so ask for each by compound name. A generic PDF with no batch number is not a batch certificate. Free Muscle-brand batches are assayed by Janoshik Analytical, an independent laboratory, with the certificate sent on request by email; that programme does not cover iMuscle. See \u003ca href=\"\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eBecause the bundle holds two compounds, expect two identity results, normally on two certificates. Read each against these points:\u003c\/p\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eName and CAS number.\u003c\/strong\u003e 317318-70-0 for Cardarine and 1165910-22-4 for LGD-4033. A heading of only \"SARM\" does not say which molecule was found.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity method.\u003c\/strong\u003e HPLC compares the sample's retention time with a reference standard. LC-MS adds a measured mass, which should match the molecular formula: a monoisotopic mass of about 453.07 for Cardarine and 338.09 for LGD-4033, usually seen as an ion about one mass unit above or below. Without an identity result, a purity figure could describe some other substance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIsomer, for LGD-4033 only.\u003c\/strong\u003e Its two stereocentres mean other isomers share its formula and mass, so a mass match alone does not prove the right form. Cardarine has no stereocentre, so the point does not arise for it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity percentage.\u003c\/strong\u003e Usually a share of the total HPLC peak area: how much of what was detected is the named compound. It does not give milligrams per capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e For most listings this tests a label claim. Here there is no label claim, so a measured figure would be the first statement of strength rather than a check on one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number, test date and laboratory.\u003c\/strong\u003e The lot must match the container, the date shows the age of the result, and a named laboratory can be asked to confirm the report.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003eA missing field leaves its question open. \u003ca href=\"\/pages\/contact\"\u003eContact us\u003c\/a\u003e with the lot numbers and we will tell you what documentation exists. See also \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eBoth compounds are banned in and out of competition. GW-501516 has been on the WADA list since January 2009, first categorised as a gene doping substance and now in section S4 (Thevis et al., 2010). LGD-4033 is named in section S1.2 among other anabolic agents. Anti-doping rules apply strict liability, so an athlete answers for any prohibited substance in a sample however it got there, and the 2017 analysis shows that a product's label is no guide to what it holds.\u003c\/p\u003e\u003cp\u003eTesting for Cardarine targets what the body makes of it as well as the parent molecule. The Cologne anti-doping laboratory synthesised the two main urinary metabolites, a sulfoxide and a sulfone formed at the sulphur atom, confirmed their structures and validated a routine urine screening method with a limit of detection of 0.1 ng\/ml (Thevis et al., 2010).\u003c\/p\u003e\u003cp\u003eNo verified study we can cite gives a detection window after capsules such as these, whose strength is not even stated. For both compounds the accurate statement is: detectable, window not established. The absence of a published window is not evidence that it is short.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eWe know of no published shelf-life study for Cardarine or LGD-4033 capsules, so we quote no shelf life. The expiry date printed by iMuscle is the working limit, and a certificate describes a batch only on its test date.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOne compound, one container.\u003c\/strong\u003e Keep each compound in its original labelled container. Capsules can look alike, and once mixed or decanted they can no longer be traced to a lot number or certificate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCool, dry and dark.\u003c\/strong\u003e A closed cupboard away from radiators, ovens and sunlit windows, with lids closed after every opening. Damp air softens capsule shells, so kitchens and bathrooms are poor choices.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep a log.\u003c\/strong\u003e Write the two lot numbers in a notebook with the dates each container was first opened; any portion sent away for testing needs its own tag naming compound, lot and date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory practice.\u003c\/strong\u003e Gloves for opened capsules, no food or drink nearby, storage out of reach of children and pets, and disposal as chemical waste under local rules, not in household bins or drains.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eA sealed container keeps its 30-day return option; once opened, it no longer qualifies.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePPAR-delta\u003c\/strong\u003e: the delta member of the peroxisome proliferator-activated receptor family; Cardarine is a synthetic ligand of it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAndrogen receptor\u003c\/strong\u003e: the receptor testosterone activates, and the target of LGD-4033.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator; LGD-4033 is one, Cardarine is not.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSHBG\u003c\/strong\u003e: sex hormone-binding globulin, a blood protein that carries testosterone and fell in the 2013 LGD-4033 study.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCarcinogenicity study\u003c\/strong\u003e: a toxicology test in which rats or mice are exposed for most of their lifespan and examined for tumours.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStereocentre\u003c\/strong\u003e: an atom allowing two mirror-image arrangements; LGD-4033 has two, Cardarine none.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC and LC-MS\u003c\/strong\u003e: separation of a dissolved sample on a column, read by a UV detector or by a mass spectrometer that also weighs each molecule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolite\u003c\/strong\u003e: a substance the body makes from another, such as Cardarine's sulfoxide and sulfone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLimit of detection\u003c\/strong\u003e: the smallest amount per millilitre a validated method can distinguish from a blank.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: the principle under which the presence of a banned substance in a sample is itself the violation, regardless of intent or how it got there.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/cardarine\"\u003eCardarine (GW-501516), all brands\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/lgd-4033\"\u003eLGD-4033 (Ligandrol), all brands\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-imuscle\"\u003eiMuscle brand collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eAll bundles\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003eCardarine (GW-501516): what happened in development\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/lgd-4033-ligandrol-research-guide\"\u003eLGD-4033 (ligandrol): the research guide\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eResearch use only. Not evaluated by the MHRA, EMA or FDA, not a food supplement, not for human consumption. Sold to adults aged 18 and over. Nothing on this page is medical or dosing advice or a suggestion that the compounds be combined.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eOlson EJ, et al. Lipid effects of peroxisome proliferator-activated receptor-delta agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Arterioscler Thromb Vasc Biol. 2012;32(9):2289-94. PMID: 22814748.\u003c\/li\u003e\n\u003cli\u003eBasaria S, et al. The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci. 2013;68(1):87-95. PMID: 22459616.\u003c\/li\u003e\n\u003cli\u003eVan Wagoner RM, et al. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004-2010. PMID: 29183075.\u003c\/li\u003e\n\u003cli\u003eThevis M, et al. Characterization of two major urinary metabolites of the PPARdelta-agonist GW1516 and implementation of the drug in routine doping controls. Anal Bioanal Chem. 2010;396(7):2479-91. PMID: 19946680.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. PMID: 34565686.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468978991330,"sku":null,"price":85.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/Combo4.jpg?v=1789931398"},{"product_id":"imuscle-cardarine-ibutamoren-andarine","title":"iMuscle Cardarine + Ibutamoren + Andarine stack","description":"\u003cp\u003e\u003cstrong\u003eiMuscle Cardarine + Ibutamoren + Andarine\u003c\/strong\u003e is a three-compound bundle from iMuscle that groups Cardarine (GW-501516), MK-677 (Ibutamoren) and Andarine (S-4), 60 capsules in total. iMuscle does not state the strength of any of the three and we do not guess at it. Free Muscle stocks it through the \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e range and supplies it for laboratory research only, not for human consumption, to adults aged 18 and over.\u003c\/p\u003e\u003cp\u003eThe bundle simply places three compounds in one listing; we make no claim that they do anything together. The page takes each compound in turn: what it is, what research measured, its UK and sporting status, and what its batch certificate should show.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eCardarine (GW-501516)\u003c\/h3\u003e\u003cp\u003eCardarine, also written GW501516 or endurobol, is a synthetic PPAR-delta agonist developed by GlaxoSmithKline and Ligand for lipid disorders; it is not a SARM. A 2012 twelve-week human trial in subjects with low HDL cholesterol recorded a rise in HDL and a fall in triglycerides, but was not designed to assess long-term safety (Olson et al., 2012). Clinical development was halted after two-year rodent carcinogenicity studies found tumours in multiple organs. Every brand we stock is on the \u003ca href=\"\/collections\/cardarine\"\u003eCardarine collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eMK-677 (Ibutamoren)\u003c\/h3\u003e\u003cp\u003eMK-677, also called ibutamoren or L-163,191, is an oral ghrelin receptor agonist and growth hormone secretagogue, not a SARM. In a 2008 two-year randomised trial in 65 healthy older adults, fat-free mass rose by about 1.1 kg versus placebo, with increased appetite, fasting glucose, insulin resistance and oedema also recorded (Nass et al., 2008). It has never been approved. See the \u003ca href=\"\/collections\/mk-677\"\u003eMK-677 collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eAndarine (S-4)\u003c\/h3\u003e\u003cp\u003eAndarine, also called S-4, is an early non-steroidal selective androgen receptor modulator from GTx. The published evidence is almost entirely preclinical: in a 2007 study in ovariectomised rats, S-4 preserved bone mass and reduced body fat (Kearbey et al., 2007). It never reached late-stage human trials and has no approval anywhere. Reports of visual disturbance are widely repeated but have not been characterised in a published controlled trial. See the \u003ca href=\"\/collections\/andarine\"\u003eAndarine collection page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eNothing summarised above is a claim about this product, and no published study has examined these compounds together.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: iMuscle\u003c\/li\u003e\n\u003cli\u003eCompounds: Cardarine (GW-501516), MK-677 (Ibutamoren) and Andarine (S-4)\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules in total across the bundle\u003c\/li\u003e\n\u003cli\u003eStrength per compound: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eBundle basis: one listing for three compounds; no combined effect is claimed\u003c\/li\u003e\n\u003cli\u003eUse: laboratory research only, not for human consumption, adults 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWith no stated strength, total milligrams per pack cannot be calculated and we do not estimate it. The single-compound iMuscle listings carry a label strength: \u003ca href=\"\/products\/imuscle-cardarine-gw501516-60-10mg\"\u003eiMuscle Cardarine GW-501516\u003c\/a\u003e, \u003ca href=\"\/products\/imuscle-ibutamoren-mk-677-60-10mg\"\u003eiMuscle Ibutamoren MK-677\u003c\/a\u003e and \u003ca href=\"\/products\/imuscle-andarine-s4-60-15mg\"\u003eiMuscle Andarine S-4\u003c\/a\u003e. How to set label strengths against each other is explained in \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCardarine, MK-677 and Andarine in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"cardarine UK legal\", \"MK 677 UK buy\" and \"MK677 UK supplier\" ask two things: may each compound be sold in Britain, and how would a buyer know what a listing holds?\u003c\/p\u003e\u003ch3\u003eThe legal position, compound by compound\u003c\/h3\u003e\u003cp\u003eNone of the three is a licensed medicine in the UK (MHRA) or an authorised food supplement. They are not controlled drugs and may be sold to adults for laboratory research, the only basis for this listing. The limits concern what they may be sold as: not as a medicine or food, and not with directions for use or a promised result.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCompound\u003c\/th\u003e\n\u003cth\u003ePharmacological class\u003c\/th\u003e\n\u003cth\u003eUK medicine licence\u003c\/th\u003e\n\u003cth\u003eWADA Prohibited List\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCardarine\u003c\/td\u003e\n\u003ctd\u003ePPAR-delta agonist\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003ctd\u003eS4, hormone and metabolic modulators\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMK-677\u003c\/td\u003e\n\u003ctd\u003eGhrelin receptor agonist, growth hormone secretagogue\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003ctd\u003eS2, growth hormone secretagogues\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAndarine\u003c\/td\u003e\n\u003ctd\u003eSelective androgen receptor modulator\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003ctd\u003eS1, anabolic agents\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eAll three are banned in tested sport at all times. MK-677 has a page of its own on \u003ca href=\"\/pages\/mk-677-legal-status-uk\"\u003eMK-677 legal status in the UK\u003c\/a\u003e, and the SARM class is introduced in \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eWhat official medicines laboratories have found\u003c\/h3\u003e\u003cp\u003eThese three compounds are among the molecules official medicines laboratories report most often. Over five years, the falsified medicines working group of the official medicines control laboratory network, whose contributors included a laboratory at the MHRA, pooled 354 results on 324 samples of SARMs, metabolic modulators and growth hormone secretagogues from 14 laboratories in 13 countries, most of them from illegal distribution (Barrios et al., 2025). Ibutamoren, ligandrol, ostarine, cardarine and andarine were the five molecules reported most often. About a quarter of the products were presented as dietary supplements, which the authors flagged because a buyer may not realise that an unapproved pharmaceutical is inside. A name on a pot is a claim; only analysis of the lot tests it.\u003c\/p\u003e\u003ch3\u003eWhat a checkable listing shows, and where this one stands\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eA named manufacturer and a named UK seller.\u003c\/strong\u003e Made by iMuscle; sold and dispatched by FreeMuscle LTD, a UK company in Scunthorpe.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated strength for every compound.\u003c\/strong\u003e Not given by iMuscle for this bundle, so it does not meet this check; the single-compound listings above do.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch paperwork for each of the three compounds.\u003c\/strong\u003e iMuscle certificates appear here only when the manufacturer provides them for the stock on our shelves.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo directions for use and no promised outcomes.\u003c\/strong\u003e None appear on this page; research use only, 18 and over.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTracked, discreet delivery.\u003c\/strong\u003e Free tracked UK delivery in plain packaging, orders placed before 2pm Monday to Friday processed the same working day, EU delivery in 3-7 working days (\u003ca href=\"\/pages\/shipping\"\u003edelivery\u003c\/a\u003e).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA returns route.\u003c\/strong\u003e Unopened items within 30 days (\u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eReviews describe delivery, not contents. Our \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e applies the same tests to any shop.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eEach compound is also sold as a research liquid (hence searches for \"MK677 UK liquid\") and as powder. None of the three is a peptide. Cardarine (molecular weight 453.5), MK-677 (528.7 as the free base) and andarine (441.4) are small synthetic molecules, and MK-677 was developed as an orally active ghrelin mimetic, which is how the 2008 trial gave it. Why swallowed peptides are a different case is covered in \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eWhat changes between formats is where the quantity per unit is fixed:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsules\u003c\/strong\u003e have their content fixed when powder is filled into shells. A measured figure per capsule is possible, but one pooled result averages away the spread between individual capsules, and in a bundle it must also be reported separately for each compound.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquids\u003c\/strong\u003e carry a concentration, so the amount in any volume drawn depends on the measuring device, on the compound having fully dissolved and on solvent not evaporating after the bottle is opened.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePowders\u003c\/strong\u003e leave every portion to the buyer's own scales, so no label figure per unit exists to check.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eSalt form matters as well. MK-677 is often supplied as the mesylate salt, which is heavier than the free base, so a label should say which form its milligrams refer to. No study has compared formats for any of these three compounds, and nothing here suggests one form behaves differently in the body. With no strength stated, the usual advantage of a capsule, a checkable figure per unit, is not yet available here.\u003c\/p\u003e\u003ch2\u003eMK-677 compared with ipamorelin\u003c\/h2\u003e\u003cp\u003eMK-677 is the most searched of the three compounds in this bundle, and \"ibutamoren vs ipamorelin\" is the comparison that appears in its search suggestions. The two share a receptor and little else.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint\u003c\/th\u003e\n\u003cth\u003eMK-677 (in this bundle)\u003c\/th\u003e\n\u003cth\u003eIpamorelin\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eChemical type\u003c\/td\u003e\n\u003ctd\u003eNon-peptide small molecule\u003c\/td\u003e\n\u003ctd\u003eSynthetic pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and molecular weight\u003c\/td\u003e\n\u003ctd\u003eC27H36N4O5S, 528.7\u003c\/td\u003e\n\u003ctd\u003eC38H49N9O5, 711.9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e159634-47-6\u003c\/td\u003e\n\u003ctd\u003e170851-70-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReceptor\u003c\/td\u003e\n\u003ctd\u003eGHS-R1a, the ghrelin receptor\u003c\/td\u003e\n\u003ctd\u003eGHS-R1a, the ghrelin receptor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRoute in published human research\u003c\/td\u003e\n\u003ctd\u003eBy mouth\u003c\/td\u003e\n\u003ctd\u003eInjected or infused, as a peptide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLength of human studies\u003c\/td\u003e\n\u003ctd\u003eRandomised trial of up to two years\u003c\/td\u003e\n\u003ctd\u003eShort pharmacology studies only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK status\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eS2, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eS2, prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eBoth compounds mimic ghrelin, the stomach hormone that signals hunger, and both prompt the pituitary gland to release its own growth hormone rather than supplying any. The differences lie in the chemistry and in the depth of the record. MK-677 is a compact molecule absorbed from the gut, and its longest trial recorded increased appetite, raised fasting glucose, reduced insulin sensitivity and oedema alongside the change in fat-free mass. Ipamorelin is a chain of five amino acids, two of them in unusual forms, and has no human study of comparable length, so its long-term profile in people is unknown rather than favourable. No trial has given both compounds to the same participants, which means neither can be ranked against the other. Ipamorelin brands are on the \u003ca href=\"\/collections\/ipamorelin\"\u003eipamorelin collection page\u003c\/a\u003e; background is in the \u003ca href=\"\/blogs\/news\/ipamorelin-research-guide\"\u003eipamorelin research guide\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/mk-677-vs-ipamorelin-vs-hgh\"\u003eMK-677 vs ipamorelin vs HGH\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eFor the other two compounds, cardarine is often set against \u003ca href=\"\/collections\/sr9009\"\u003eSR9009\u003c\/a\u003e and andarine against \u003ca href=\"\/collections\/ostarine\"\u003eostarine\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eCertificates for this bundle come from iMuscle, not from us, and we display one only when iMuscle provides it for the batch in our stock. Because each of the three compounds may come from its own production lot, request paperwork by compound name. A PDF without a batch number is not a batch certificate. The Janoshik Analytical programme, under which an independent laboratory assays every Free Muscle-brand batch and the certificate is emailed on request, does not extend to iMuscle.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCompound\u003c\/th\u003e\n\u003cth\u003eCAS number\u003c\/th\u003e\n\u003cth\u003eFormula and molecular weight\u003c\/th\u003e\n\u003cth\u003ePoint to check\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCardarine\u003c\/td\u003e\n\u003ctd\u003e317318-70-0\u003c\/td\u003e\n\u003ctd\u003eC21H18F3NO3S2, 453.5\u003c\/td\u003e\n\u003ctd\u003eNo stereocentre, so there is no mirror-image form to rule out\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMK-677\u003c\/td\u003e\n\u003ctd\u003e159634-47-6\u003c\/td\u003e\n\u003ctd\u003eC27H36N4O5S, 528.7 (free base)\u003c\/td\u003e\n\u003ctd\u003eWhether results are expressed as free base or mesylate salt\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAndarine\u003c\/td\u003e\n\u003ctd\u003e401900-40-1\u003c\/td\u003e\n\u003ctd\u003eC19H18F3N3O6, 441.4\u003c\/td\u003e\n\u003ctd\u003eThe (2S) form; its mirror image has the same mass\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity.\u003c\/strong\u003e An HPLC retention time matched to a reference standard, or an LC-MS mass that fits the formula above. A certificate that names one compound says nothing about the other two.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e Usually a percentage of HPLC peak area. It grades what the material is, not how much of it a capsule holds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e For this bundle there is no label figure to compare it with, so a measured content would be the first statement of strength anyone has made, not a check on one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLot, date and issuing laboratory.\u003c\/strong\u003e Compare the lot code with the label on your pot; the date shows the result's age, and a named laboratory can verify it.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eFor this brand, a missing field leaves a specific question open. No certificate means nothing independent confirms which compounds are present. Identity without content confirms presence, not quantity. \u003ca href=\"\/pages\/contact\"\u003eContact us\u003c\/a\u003e with the lot numbers and we will tell you what documentation exists. See also \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e and our \u003ca href=\"\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eEach compound in this bundle sits in a different section of the WADA Prohibited List, applied in the UK by UK Anti-Doping: andarine in S1, MK-677 in S2 and cardarine in S4. All three are prohibited in and out of competition. Under strict liability an athlete answers for any prohibited substance in their sample, whatever its source.\u003c\/p\u003e\u003cp\u003eCardarine has the most detailed published detection work of the three. It entered the WADA list in January 2009, first categorised as a gene doping substance. The Cologne anti-doping laboratory then identified its two main urinary metabolites, a sulfoxide and a sulfone, and validated a urine screening method with a limit of detection of 0.1 ng\/ml that was brought into routine doping controls (Thevis et al., 2010). MK-677 and andarine are also screened for by accredited laboratories, but no verified study cited here gives a window for any of the three after capsules of unstated strength. The accurate answer for each is: detectable, window not established.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eWe know of no published shelf-life study for cardarine, MK-677 or andarine in capsule form, so no shelf life is stated here. Any expiry date iMuscle prints is the limit to work to, and a certificate describes a batch only on the day it was tested.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCheck on arrival.\u003c\/strong\u003e Confirm the seal is intact and note each lot number with the date received. Opening a container ends the 30-day return option, which covers unopened items only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStore closed, cool, dry and dark.\u003c\/strong\u003e Humidity in kitchens and bathrooms can soften or crack capsule shells. Leave any desiccant sachet in place and close the lid straight after opening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep each compound traceable.\u003c\/strong\u003e Do not decant, mix or relabel capsules. Once separated from the container, a capsule has no link to its lot number or certificate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHandle as laboratory chemicals.\u003c\/strong\u003e Gloves when handling opened capsules or powder, no food or drink in the work area, storage out of reach of children and pets, and disposal as chemical waste under local rules, never in household bins or drains.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePPAR-delta\u003c\/strong\u003e: a receptor inside the cell nucleus that controls genes for using fatty acids as fuel; cardarine was designed to switch it on.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHS-R1a\u003c\/strong\u003e: the growth hormone secretagogue receptor, also called the ghrelin receptor, through which MK-677 and ipamorelin act.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth hormone secretagogue\u003c\/strong\u003e: any substance that prompts the pituitary gland to release growth hormone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator; andarine is one, while cardarine and MK-677 are not.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCarcinogenicity study\u003c\/strong\u003e: a long-term animal study that looks for tumours; the finding that stopped cardarine's development.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree base and mesylate\u003c\/strong\u003e: the uncharged molecule and its heavier methanesulfonate salt; equal milligrams of each hold different amounts of ibutamoren.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLimit of detection\u003c\/strong\u003e: the lowest concentration a validated method can reliably report, a measure of sensitivity rather than time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: in anti-doping, the principle that intent does not matter; a positive sample is a violation even when a product was mislabelled.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/cardarine\"\u003eCardarine (GW-501516), all brands\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003ecardarine: what happened in development\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren), all brands\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/mk-677-ibutamoren-what-the-research-says\"\u003eMK-677: what the research says\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/andarine\"\u003eAndarine (S-4), all brands\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/ipamorelin\"\u003eIpamorelin\u003c\/a\u003e, compared above\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-imuscle\"\u003eiMuscle brand collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eAll bundles\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eResearch use only. Not evaluated by the MHRA, EMA or FDA, not a food supplement, not for human consumption. Sold to adults aged 18 and over. Nothing on this page is medical or dosing advice or a suggestion that the compounds be combined.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eOlson EJ, et al. Lipid effects of peroxisome proliferator-activated receptor-delta agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Arterioscler Thromb Vasc Biol. 2012;32(9):2289-94. PMID: 22814748.\u003c\/li\u003e\n\u003cli\u003eNass R, et al. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008;149(9):601-11. PMID: 18981485.\u003c\/li\u003e\n\u003cli\u003eKearbey JD, et al. Selective androgen receptor modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats. Pharm Res. 2007;24(2):328-35. PMID: 17063395.\u003c\/li\u003e\n\u003cli\u003eBarrios MM, et al. SARMs, Metabolic Modulators and Growth Hormone Secretagogues in Suspected Illegal Medicines, Bought as Sport Performance Enhancers: A Retro- and Prospective Study Within the GEON. Drug Test Anal. 2025;17(10):2078-2085. PMID: 40551438.\u003c\/li\u003e\n\u003cli\u003eThevis M, et al. Characterization of two major urinary metabolites of the PPARdelta-agonist GW1516 and implementation of the drug in routine doping controls. Anal Bioanal Chem. 2010;396(7):2479-91. PMID: 19946680.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468979024098,"sku":null,"price":121.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/CardarineIbutamorenAndarine_f4b875eb-368c-4d5e-afbf-f01a1688b29e.jpg?v=1789931400"},{"product_id":"imuscle-cardarine-ostarine-mk2866","title":"iMuscle Cardarine + Ostarine MK-2866 stack","description":"\u003cp\u003e\u003cstrong\u003eiMuscle Cardarine + Ostarine MK-2866\u003c\/strong\u003e is a two-compound bundle from iMuscle that pairs Cardarine (GW-501516) with Ostarine (MK-2866), 60 capsules in total. iMuscle does not state the strength of either compound and we do not guess at it. The bundle is a pricing convenience for buying both in one listing; we make no claim that the two do anything together. Supplied for laboratory research only, not for human consumption, to adults aged 18 and over.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eCardarine (GW-501516)\u003c\/h3\u003e\u003cp\u003eCardarine, also written GW501516 or endurobol, is a synthetic PPAR-delta agonist developed by GlaxoSmithKline and Ligand for lipid disorders; it is not a SARM. A 2012 twelve-week human trial in subjects with low HDL cholesterol recorded a rise in HDL and a fall in triglycerides, but was not designed to assess long-term safety (Olson et al., 2012). Clinical development was halted after two-year rodent carcinogenicity studies found tumours in multiple organs. Every brand we stock is on the \u003ca href=\"\/collections\/cardarine\"\u003eCardarine collection page\u003c\/a\u003e, and the history is told in \u003ca href=\"\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003ecardarine: what happened in development\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eOstarine (MK-2866)\u003c\/h3\u003e\u003cp\u003eOstarine, also called MK-2866 or enobosarm, is a non-steroidal selective androgen receptor modulator developed by GTx for muscle wasting and the most clinically studied SARM. In a 2011 placebo-controlled Phase 2 trial in 120 healthy elderly men and postmenopausal women, lean body mass rose by an average of 1.3 kg more than placebo over twelve weeks at the highest dose studied. HDL cholesterol fell in a dose-dependent way, eight participants had transient rises in the liver enzyme ALT, and one was withdrawn for this reason (Dalton et al., 2011). Later Phase 3 trials in people with cancer-related muscle loss did not lead to approval. See the \u003ca href=\"\/collections\/ostarine\"\u003eOstarine collection page\u003c\/a\u003e and the \u003ca href=\"\/blogs\/news\/ostarine-mk-2866-research-guide\"\u003eostarine research guide\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eNothing summarised above is a claim about this product, and we know of no published study that has examined these compounds together.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: iMuscle\u003c\/li\u003e\n\u003cli\u003eCompounds: Cardarine (GW-501516) and Ostarine (MK-2866)\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules in total across the bundle\u003c\/li\u003e\n\u003cli\u003eStrength per compound: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eBundle basis: pricing convenience only; no combined effect is claimed\u003c\/li\u003e\n\u003cli\u003eUse: laboratory research only, not for human consumption, adults 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWith no stated strength, total milligrams per pack cannot be calculated and we do not estimate it. The single-compound listings, \u003ca href=\"\/products\/imuscle-cardarine-gw501516-60-10mg\"\u003eiMuscle Cardarine GW-501516\u003c\/a\u003e and \u003ca href=\"\/products\/imuscle-ostarine-k2866-60-15mg\"\u003eiMuscle Ostarine MK-2866\u003c\/a\u003e, carry a label strength; see \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e for how to compare them.\u003c\/p\u003e\u003ch2\u003eCardarine and Ostarine in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"cardarine UK legal\", \"MK 2866 buy UK\" and \"cardarine UK reviews\" ask two things: is the purchase lawful, and will the seller send what the label says.\u003c\/p\u003e\u003ch3\u003eThe legal position\u003c\/h3\u003e\u003cp\u003eThis bundle contains Cardarine and Ostarine. Neither is a licensed medicine in the UK (MHRA) or an authorised food supplement. They are not controlled drugs and may be sold to adults for laboratory research, the only basis for this listing. Selling either with directions for human use, or with promises of physical results, could bring the product within the legal definition of a medicine, which is why this page gives neither. Both are on the WADA Prohibited List, Cardarine under S4 (hormone and metabolic modulators) and Ostarine under S1 (anabolic agents), and are banned in tested sport at all times. The class is introduced in \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e, although only ostarine belongs to it.\u003c\/p\u003e\u003ch3\u003eSigns of a listing that can be checked\u003c\/h3\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eA manufacturer and a seller you can name.\u003c\/strong\u003e Here the maker is iMuscle and the seller is FreeMuscle LTD, a UK company based in Scunthorpe.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA batch number on every pot.\u003c\/strong\u003e Without one, no document can be matched to what arrived.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate for that batch, not a sample PDF.\u003c\/strong\u003e For iMuscle we show one only where the manufacturer supplies it for the batch we hold.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated strength.\u003c\/strong\u003e This is where the bundle falls short, because iMuscle does not state one; we say so rather than fill the gap.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo usage directions or result claims.\u003c\/strong\u003e A listing that offers them is not selling for research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePlain, tracked delivery and a returns route.\u003c\/strong\u003e Every UK order ships free and tracked in plain packaging; orders placed before 2pm Monday to Friday are processed the same working day; EU delivery takes 3-7 working days; unopened items can be returned within 30 days. Details are on the \u003ca href=\"\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003eReviews describe delivery and service; only a laboratory analysis of the lot can confirm what a capsule contains. A longer checklist sits in \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e, and the other brands on this marketplace are introduced on the \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e page.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eSearches for \"ostarine liquid UK\", \"ostarine tablets UK\" and \"ostarine capsules UK\" show that buyers meet the same molecule in several formats. The format does not alter the chemistry; it alters how the amount in each unit is fixed and how easily a certificate can speak to it.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFormat\u003c\/th\u003e\n\u003cth\u003eWhere the amount is set\u003c\/th\u003e\n\u003cth\u003eWhat can drift\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCapsule\u003c\/td\u003e\n\u003ctd\u003eAt the factory, when powder is filled into shells\u003c\/td\u003e\n\u003ctd\u003eFill weight between capsules; a pooled assay reports the average\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTablet\u003c\/td\u003e\n\u003ctd\u003eAt the factory, when powder is blended with excipients and pressed\u003c\/td\u003e\n\u003ctd\u003eBlend uniformity; excipients add peaks to be explained on a chromatogram\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLiquid\u003c\/td\u003e\n\u003ctd\u003eBy the concentration written on the bottle\u003c\/td\u003e\n\u003ctd\u003eMeasuring accuracy of each portion, evaporation after opening, settling in the cold\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLoose powder\u003c\/td\u003e\n\u003ctd\u003eBy whoever weighs it\u003c\/td\u003e\n\u003ctd\u003eBalance accuracy and static cling at small masses\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eBoth compounds here are small synthetic molecules, not peptides: ostarine has a molecular weight of 389.3 and cardarine 453.5. The digestive breakdown that limits swallowed peptides, covered in \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e, is therefore not the relevant issue for either. We know of no study comparing retail formats of either compound. A capsule with a declared strength is simply the easiest format to check, and this bundle lacks that declaration.\u003c\/p\u003e\u003ch2\u003eOstarine compared with MK-677\u003c\/h2\u003e\u003cp\u003e\"MK 2866 vs MK 677\" is one of the most common comparison searches for ostarine, largely because the two codes look alike. The shared \"MK\" prefix is a development code and says nothing about how the molecules act. They sit in different drug classes, bind different receptors and fall under different sections of the WADA list.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eOstarine (in this bundle)\u003c\/th\u003e\n\u003cth\u003eMK-677\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOther names\u003c\/td\u003e\n\u003ctd\u003eMK-2866, enobosarm, GTx-024\u003c\/td\u003e\n\u003ctd\u003eIbutamoren, L-163,191\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eClass\u003c\/td\u003e\n\u003ctd\u003eSelective androgen receptor modulator\u003c\/td\u003e\n\u003ctd\u003eGrowth hormone secretagogue, a non-peptide ghrelin mimetic\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTarget\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor\u003c\/td\u003e\n\u003ctd\u003eGhrelin receptor (growth hormone secretagogue receptor)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and molecular weight\u003c\/td\u003e\n\u003ctd\u003eC19H14F3N3O3, 389.3\u003c\/td\u003e\n\u003ctd\u003eC27H36N4O5S, 528.7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMain human evidence\u003c\/td\u003e\n\u003ctd\u003ePhase 2 and Phase 3 trials in older adults and people with cancer-related muscle loss\u003c\/td\u003e\n\u003ctd\u003ePlacebo-controlled trials, including a two-year study in healthy older adults\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAdverse findings recorded\u003c\/td\u003e\n\u003ctd\u003eLower HDL cholesterol, transient liver enzyme rises\u003c\/td\u003e\n\u003ctd\u003eRaised fasting glucose, reduced insulin sensitivity, increased appetite, mild oedema\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLicensed as a medicine\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA section\u003c\/td\u003e\n\u003ctd\u003eS1, anabolic agents\u003c\/td\u003e\n\u003ctd\u003eS2, peptide hormones, growth factors, related substances and mimetics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThe MK-677 row on adverse findings comes from the 2008 trial by Nass and colleagues, in which 65 healthy adults aged 60 to 81 were randomised to MK-677 or placebo. Growth hormone and IGF-1 rose into the young-adult range and fat-free mass increased by 1.1 kg against a 0.5 kg fall on placebo, but fasting glucose rose, insulin sensitivity fell, cortisol increased, and the gain in fat-free mass was not matched by any change in strength or function (Nass et al., 2008). Set that beside the ostarine trial above and the difference is one of route: ostarine acts at the androgen receptor directly, while MK-677 works upstream by prompting the pituitary to release growth hormone. Neither trial compared the two, and we know of no study that has.\u003c\/p\u003e\u003cp\u003eMK-677 brands are listed in the \u003ca href=\"\/collections\/mk-677\"\u003eMK-677 collection\u003c\/a\u003e, its evidence is summarised in \u003ca href=\"\/blogs\/news\/mk-677-ibutamoren-what-the-research-says\"\u003eMK-677 (ibutamoren): what the research says\u003c\/a\u003e, and its UK position is set out on the \u003ca href=\"\/pages\/mk-677-legal-status-uk\"\u003eMK-677 legal status\u003c\/a\u003e page. Cardarine, the other half of this bundle, is often mentioned alongside SR9009, which acts on a different receptor family altogether; see the \u003ca href=\"\/collections\/sr9009\"\u003eSR9009 collection\u003c\/a\u003e and the \u003ca href=\"\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eiMuscle is a third-party brand, so any certificate of analysis is the manufacturer's. We show one only where iMuscle supplies it for the batch we hold. A bundle may draw on a separate batch per compound, so expect one certificate per compound and ask for each by name. A generic PDF with no batch number is not a batch certificate. Free Muscle-brand batches are assayed by Janoshik Analytical, an independent laboratory, with the certificate sent on request by email; that programme does not cover iMuscle. Our approach is set out on the \u003ca href=\"\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\u003cp\u003eWork through each certificate in this order:\u003c\/p\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eMatch the lot.\u003c\/strong\u003e The batch number on the certificate must be the one printed on the pot in front of you. If they differ, the document describes other capsules.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCheck the identity method.\u003c\/strong\u003e HPLC compared against a reference standard, or LC-MS giving a mass consistent with the formula. For ostarine that is C19H14F3N3O3 (CAS 841205-47-8); for cardarine C21H18F3NO3S2 (CAS 317318-70-0). Ostarine has one stereocentre and the active form is (2S), which a mass alone cannot distinguish from its mirror image; cardarine has no stereocentre.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreat purity as purity.\u003c\/strong\u003e A figure such as 99% describes how clean the detected material is, measured by peak area on a chromatogram. It is silent on how many milligrams sit in each capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLook for a content figure.\u003c\/strong\u003e A measured amount per capsule is the field that would matter most here, because there is no label strength to check it against.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWho tested it, and when.\u003c\/strong\u003e An unnamed laboratory cannot be asked to confirm a report, and an old test date says nothing about storage since.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003eWhere a field is absent, the certificate has simply not answered that question. Send the product name and both batch numbers through our \u003ca href=\"\/pages\/contact\"\u003econtact page\u003c\/a\u003e and we will say what paperwork iMuscle has provided. Further detail is in \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eBoth compounds are prohibited in and out of competition. Ostarine is listed in section S1 of the WADA Prohibited List as an anabolic agent and cardarine in section S4 among hormone and metabolic modulators. Anti-doping rules work on strict liability: a prohibited substance in a sample is the athlete's responsibility, whatever route it took, including a contaminated or mislabelled product.\u003c\/p\u003e\u003cp\u003eFor ostarine, sensitivity is well documented. Researchers at the German Sport University Cologne gave volunteers single and repeated oral amounts of 1, 10 and 50 micrograms, chosen to model supplement contamination rather than deliberate use, and analysed urine by LC-MS\/MS (Walpurgis et al., 2020). A single 1 microgram amount could still be found for up to nine days when ostarine was targeted, and up to five days for its glucuronide. Detection times lengthened as the amount rose, and varied widely between people.\u003c\/p\u003e\u003cp\u003eNo verified study we can cite gives a window after milligram amounts of ostarine, or any urinary window for cardarine after capsules of unstated strength. For both compounds in this bundle the accurate statement is: detectable, window not established. Anyone subject to an anti-doping code should regard any contact with either as a risk of an adverse finding.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eNo published shelf-life study of ostarine or cardarine capsules is available to cite, so we quote no shelf life and rely on the expiry date iMuscle prints on each pot.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOne compound, one pot.\u003c\/strong\u003e Keep cardarine and ostarine in their own original containers. Capsules from a bundle can look alike, and once decanted or mixed they cannot be traced back to a batch number or a certificate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTemperature and light.\u003c\/strong\u003e A cool cupboard away from heaters, ovens and direct sunlight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMoisture.\u003c\/strong\u003e Replace the lid straight after opening and leave any desiccant sachet in place. Gelatin and plant-based shells absorb water, which can soften them and let the contents clump.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePaper trail.\u003c\/strong\u003e Keep a simple log for each pot: compound, batch number, date received, date opened. Any portion set aside for testing gets the same three details on its own label.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory practice.\u003c\/strong\u003e Wear gloves for opened capsules, keep food and drink away from the work area, store out of reach of children and pets, and dispose of unwanted material as chemical waste under local rules, not in household bins or drains.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThe 30-day return option applies only while a pot is still sealed, so check the batch details against any certificate before opening.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: short for selective androgen receptor modulator. The label fits ostarine in this bundle but not cardarine, which does not act at the androgen receptor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePPAR-delta\u003c\/strong\u003e: one of three peroxisome proliferator-activated receptors inside the cell nucleus; cardarine was designed to activate this subtype selectively.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGhrelin mimetic\u003c\/strong\u003e: a compound that copies the action of the hormone ghrelin at its receptor, as MK-677 does.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCarcinogenicity study\u003c\/strong\u003e: a regulatory toxicology test in which animals receive a substance for most of their lifespan and are examined for tumours; the cardarine findings came from studies of this kind.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHDL cholesterol\u003c\/strong\u003e: the lipoprotein fraction that rose in the cardarine lipid trial and fell in the ostarine Phase 2 trial.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlucuronide\u003c\/strong\u003e: a form of a compound the body links to glucuronic acid for excretion, often a target in urine testing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: under anti-doping codes, a positive sample is an offence in itself; intent and source affect only the sanction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnantiomer\u003c\/strong\u003e: either of two mirror-image versions of a molecule with one stereocentre. Ostarine has two; cardarine has no mirror-image form.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChromatogram\u003c\/strong\u003e: the trace an HPLC run produces; each peak is a separated substance, and the main peak's share of the total area gives the purity figure.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/cardarine\"\u003eCardarine (GW-501516), all brands\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/ostarine\"\u003eOstarine (MK-2866), all brands\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/mk-677\"\u003eMK-677, all brands\u003c\/a\u003e and \u003ca href=\"\/collections\/sarms\"\u003eall SARMs\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-imuscle\"\u003eiMuscle brand collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eAll bundles\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/faq\"\u003eFrequently asked questions\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eResearch use only. Not evaluated by the MHRA, EMA or FDA, not a food supplement, not for human consumption. Sold to adults aged 18 and over. Nothing on this page is medical or dosing advice or a suggestion that the compounds be combined; research summaries describe findings in study participants, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eOlson EJ, et al. Lipid effects of peroxisome proliferator-activated receptor-delta agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Arterioscler Thromb Vasc Biol. 2012;32(9):2289-94. PMID: 22814748.\u003c\/li\u003e\n\u003cli\u003eDalton JT, et al. The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial. J Cachexia Sarcopenia Muscle. 2011;2(3):153-161. PMID: 22031847.\u003c\/li\u003e\n\u003cli\u003eNass R, et al. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008;149(9):601-11. PMID: 18981485.\u003c\/li\u003e\n\u003cli\u003eWalpurgis K, et al. Elimination profiles of microdosed ostarine mimicking contaminated products ingestion. Drug Test Anal. 2020;12(11-12):1570-1580. PMID: 32959982.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468979056866,"sku":null,"price":82.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/Combo1_eea04d8f-0b97-4e11-94ad-6c34c7f253ae.jpg?v=1789931403"},{"product_id":"imuscle-cardarine-testolon-rad140","title":"iMuscle Cardarine + Testolone RAD-140 stack","description":"\u003cp\u003eThe iMuscle Cardarine and Testolone bundle pairs two research compounds from iMuscle in one listing: cardarine (GW-501516, endurobol), a PPAR-delta agonist, and testolone (RAD-140, vosilasarm), a selective androgen receptor modulator. iMuscle lists the pack as 60 capsules. The manufacturer does not state a strength per capsule on this listing, so we do not quote one. Supplied to adults aged 18 and over for laboratory research only, and not for human consumption.\u003c\/p\u003e\u003cp\u003eA bundle is a listing convenience only: it groups two compounds from one manufacturer under a single product listing. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product. Each section below therefore treats cardarine first and RAD-140 second, as two unrelated substances that simply share a listing.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eCardarine (GW-501516)\u003c\/h3\u003e\u003cp\u003eCardarine is not a SARM but an agonist at the PPAR-delta nuclear receptor, which regulates genes for fatty-acid oxidation. GlaxoSmithKline developed it with Ligand as a candidate for lipid disorders. The first published study in people was a two-week 2007 trial in healthy volunteers kept in hospital and sedentary: HDL cholesterol was higher than with placebo, fasting triglycerides trended downwards without reaching statistical significance, and fat from a test meal was cleared faster (Sprecher et al., 2007). With 6 people on placebo and 18 on the compound, it could say nothing about long-term tolerability. Development was then discontinued after long-term rodent toxicology studies found tumours in several organs, a sponsor-reported finding that ended further human work. Cardarine has never been approved as a medicine. Compare brands on the \u003ca href=\"\/collections\/cardarine\"\u003eCardarine (GW-501516) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eTestolone (RAD-140)\u003c\/h3\u003e\u003cp\u003eTestolone (RAD-140) is a non-steroidal SARM designed by Radius Health and described in 2011 as potent and orally bioavailable, with its early characterisation carried out in rats and non-human primates (Miller et al., 2011). Human data are limited to a small early oncology study: 22 postmenopausal women with advanced ER-positive, HER2-negative breast cancer (LoRusso et al., 2022). Raised liver enzymes were the most frequent adverse events, AST in 59.1% of patients and ALT in 45.5%, alongside raised bilirubin, vomiting, dehydration and weight loss, and 16 of the 22 had at least one grade 3 or 4 event. The measured half-life was 44.7 hours. Published case reports describe drug-induced liver injury in adults who had taken products labelled as containing RAD-140; in one, a 52-year-old man's liver enzymes took about three months to return to normal (Barbara et al., 2020). It remains investigational and has never been approved as a medicine. Compare brands on the \u003ca href=\"\/collections\/rad-140\"\u003eTestolone (RAD-140) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eThese findings describe study participants and animals under trial conditions. None of them is a claim about the capsules in this bundle.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: iMuscle (third-party brand, Muscle Market)\u003c\/li\u003e\n\u003cli\u003eCompounds: cardarine (GW-501516), testolone (RAD-140)\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eCOA: only where iMuscle supplies one for the batch held\u003c\/li\u003e\n\u003cli\u003eTerms: laboratory research only, adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eBecause no strength is printed, the usual comparison of total milligrams per pack, and of cost per milligram, cannot be made for this bundle. The method, for listings that do state a strength, is in \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCardarine and RAD-140 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eBehind \"cardarine UK legal\", \"cardarine UK buy\" and \"testolone RAD 140 UK\" sit two questions: is the sale lawful, and how can a credible seller be told from a doubtful one.\u003c\/p\u003e\u003ch3\u003eThe legal position\u003c\/h3\u003e\u003cp\u003eNone of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement. Cardarine and RAD-140 are not controlled substances in the UK, so they can be supplied to adults for laboratory research, which is the only basis on which Free Muscle sells them. The position in sport is stricter: RAD-140 falls under WADA section S1 (anabolic agents) and cardarine under S4 (hormone and metabolic modulators), and both are banned at all times, in and out of competition. Background: our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eWhat a credible UK listing shows, and where this one stands\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCheck\u003c\/th\u003e\n\u003cth\u003eWhy it matters\u003c\/th\u003e\n\u003cth\u003eThis listing\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eNamed manufacturer and UK seller\u003c\/td\u003e\n\u003ctd\u003eSomeone accountable for what is in the pack and for the sale\u003c\/td\u003e\n\u003ctd\u003eMade by iMuscle; sold and posted by FreeMuscle LTD of Scunthorpe, a UK company\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStated strength for each compound\u003c\/td\u003e\n\u003ctd\u003eWithout it, a certificate has no label figure to test\u003c\/td\u003e\n\u003ctd\u003eNot stated by iMuscle, so not quoted by us\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCertificate tied to a batch number\u003c\/td\u003e\n\u003ctd\u003eOnly a batch-specific result says anything about the pack you receive\u003c\/td\u003e\n\u003ctd\u003eShown only where iMuscle supplies one for the batch we hold\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eResearch-only wording\u003c\/td\u003e\n\u003ctd\u003eA seller giving amounts or promising outcomes is marketing a product for people to take\u003c\/td\u003e\n\u003ctd\u003eNo amounts, schedules or outcome claims; 18 and over only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDiscreet, traceable delivery\u003c\/td\u003e\n\u003ctd\u003eA tracked parcel can be followed and a plain one draws no attention\u003c\/td\u003e\n\u003ctd\u003eSent free by tracked UK post in unmarked packaging; weekday orders placed by 2pm processed that day; 3-7 working days to the EU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA returns route\u003c\/td\u003e\n\u003ctd\u003eShows the seller stands behind the order\u003c\/td\u003e\n\u003ctd\u003eUnopened items within 30 days, under our \u003ca href=\"\/pages\/shipping\"\u003edelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e terms\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eReviews and \"cardarine UK reviews\" threads tell you how a parcel arrived, not what the capsules hold. A fuller supplier checklist is in \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eBoth molecules are also sold as liquids, loose powder and occasionally injectables. The chemical is the same; what differs is how the quantity per unit is fixed and how well it holds.\u003c\/p\u003e\u003cp\u003eIn a capsule the amount is decided once, when powder is blended and filled into shells, so the figure can be checked by assaying a sample of capsules. The weak point is mixing: an assay reports an average, so a poorly blended batch can vary between shells. A liquid is sold as a concentration, so every measured portion depends on the accuracy of the volume drawn, and a solution that is opened repeatedly can lose solvent and become more concentrated, while a compound near its solubility limit can settle out in the cold. Powder has no preset portion; accuracy rests on the balance. As for injectable versions, both human studies cited here gave the compounds by mouth, and we know of no published injection study.\u003c\/p\u003e\u003cp\u003eNeither compound is a peptide. At molecular weights of 453.5 (cardarine) and 393.8 (RAD-140) they are small synthetic molecules, so the debate over whether stomach enzymes break down swallowed peptides, covered in \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e, does not apply to them in the same way. For this particular bundle, the main advantage of capsules, a printed figure per capsule that a laboratory can confirm, is missing because iMuscle prints none.\u003c\/p\u003e\u003ch2\u003eEach compound compared with its most-searched counterpart\u003c\/h2\u003e\u003cp\u003eSearchers pair each compound here with a different neighbour, \"stenabolic vs cardarine\" and \"RAD 140 vs RAD 150\", so the pairings are taken in turn.\u003c\/p\u003e\u003ch3\u003eCardarine compared with SR9009 (stenabolic)\u003c\/h3\u003e\u003cp\u003eThey are often shelved together, but share neither receptor nor chemical family. Cardarine binds PPAR-delta; SR9009 (C20H24ClN3O4S, CAS 1379686-30-2) binds REV-ERB alpha and beta, nuclear receptors that form part of the body clock. Cardarine went through industry clinical trials for lipid disorders before its tumour findings in rodents; SR9009 came out of academic research at the Scripps Research Institute and has never been given to people in a published trial. So SR9009 has no human data and no long-term carcinogenicity data, a gap in knowledge rather than a reassurance. Neither is licensed anywhere, and WADA lists both under S4 as metabolic modulators. SR9009 brands are in the \u003ca href=\"\/collections\/sr9009\"\u003eSR9009 (Stenabolic) collection\u003c\/a\u003e, with background in the \u003ca href=\"\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eRAD-140 compared with RAD-150 (TLB-150)\u003c\/h3\u003e\u003cp\u003eRAD-150, also sold as TLB-150, is marketed as an ester of RAD-140: the same core molecule with a benzoate group attached. Closely related chemically, they differ sharply in evidence: RAD-140 has a peer-reviewed preclinical paper, a published first-in-human study and anti-doping research. RAD-150 has no peer-reviewed journal studies and no published data in people, so any claim that it is longer-lasting, milder or stronger than RAD-140 is untested. Neither has ever been approved as a medicine. RAD-140 is named in WADA section S1; RAD-150 is not named individually, but S1 also covers substances with a similar chemical structure or biological effect, so it is prohibited in sport as well. RAD-150 brands are in the \u003ca href=\"\/collections\/rad-150\"\u003eRAD-150 (TLB-150) collection\u003c\/a\u003e, with more in \u003ca href=\"\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150 (TLB-150)\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eiMuscle is a third-party brand sold through Muscle Market. For third-party brands we display a certificate of analysis only where the manufacturer supplies one for the exact batch we hold; if none is shown, none has been supplied and we do not substitute a generic document. Free Muscle-brand products, by contrast, are assayed batch by batch at Janoshik Analytical, with the certificate sent on request by email; that programme does not extend to iMuscle. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e explains what a certificate shows.\u003c\/p\u003e\u003cp\u003eTwo compounds need two identity results. Read each certificate field by field:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound name and CAS number.\u003c\/strong\u003e Cardarine is CAS 317318-70-0 and RAD-140 is CAS 1182367-47-0.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity test.\u003c\/strong\u003e HPLC matches the sample against a reference standard by retention time; LC-MS also measures mass, which should correspond to 453.5 for cardarine (C21H18F3NO3S2) and 393.8 for RAD-140 (C20H16ClN5O2).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStereochemistry, for RAD-140.\u003c\/strong\u003e RAD-140 has two stereocentres, written (1R,2S) in its systematic name, so other isomers share its formula and mass. A mass match alone does not show the correct isomer. Cardarine has no stereocentre, so the question does not arise.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e A percentage, usually from chromatogram peak areas, of how much detected material is the named compound; other peaks are impurities. It is not a content per capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMeasured content.\u003c\/strong\u003e iMuscle prints no strength, so any milligram figure on a certificate would be new information about the pack, with no label value to hold it against.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLot code, date and issuer.\u003c\/strong\u003e Match the lot code to the one on your container, see how long ago the analysis was run, and note who ran it, since a named laboratory can be asked about its own report.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eTreat a blank field as an open question rather than a pass, and \u003ca href=\"\/pages\/contact\"\u003eget in touch\u003c\/a\u003e quoting the lot codes printed on the pack to learn what paperwork iMuscle has provided. See \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eFor anyone under anti-doping rules, both compounds are prohibited at all times. Under strict liability, a mislabelled or contaminated product is no defence.\u003c\/p\u003e\u003cp\u003eCardarine was added to the WADA list in January 2009, first classed as gene doping. The Cologne anti-doping laboratory then used human liver microsomes to reproduce its breakdown, synthesised the two main urinary metabolites, a sulfoxide and a sulfone, and validated a routine urine screening method able to detect 0.1 ng\/ml (Thevis et al., 2010). Testing therefore targets what the body makes from cardarine, not only the parent compound.\u003c\/p\u003e\u003cp\u003eRAD-140 is named in section S1, and anti-doping laboratories screen urine for SARMs. Its half-life in the 2022 cancer study was 44.7 hours, but a half-life describes how blood levels fall, not how long a laboratory can find traces in urine. We know of no verified study giving a detection window after capsule quantities of either compound, so for both the accurate statement is: detectable, window not established.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eWe are not aware of any published shelf-life study for cardarine or RAD-140 capsules, so no shelf life is quoted here. Treat the expiry date printed by iMuscle as the limit, and remember that a certificate describes the batch only as it stood on the day it was tested.\u003c\/p\u003e\u003cp\u003eBoth are solids held in capsule shells, and the main threats to them are moisture, heat and light. Humid air softens gelatin and lets the powder inside clump, so store the containers tightly closed in a cool, dark cupboard, well away from radiators, cookers, bathrooms and sunny windowsills. Keep capsules in their original labelled containers: loose capsules of similar appearance cannot be told apart afterwards, and once separated from the label they can no longer be linked to a batch number or certificate.\u003c\/p\u003e\u003cp\u003eLog each batch number with the date its seal was first broken. Handle opened capsules with gloves, away from food and drink, keep everything out of reach of children and pets, and dispose of unwanted material as chemical waste under local rules, never in household bins or drains. Opening a container also ends the 30-day return option, which covers unopened items only.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePPAR-delta\u003c\/strong\u003e: a nuclear receptor, full name peroxisome proliferator-activated receptor delta, switched on by cardarine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: a non-steroidal molecule built to act on the androgen receptor, such as RAD-140; cardarine belongs to a different class.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eREV-ERB alpha and beta\u003c\/strong\u003e: clock-linked nuclear receptors bound by SR9009, unrelated to PPAR-delta.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEster\u003c\/strong\u003e: a molecule made by joining an acid to an alcohol; RAD-150 is sold as RAD-140 joined to benzoic acid.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eER-positive, HER2-negative\u003c\/strong\u003e: a breast cancer type defined by oestrogen receptor presence and absence of HER2 protein excess, the population in the RAD-140 trial.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAST and ALT\u003c\/strong\u003e: enzymes released from liver cells; blood levels above normal point to liver injury or stress.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCarcinogenicity study\u003c\/strong\u003e: lifelong animal exposure to a substance, run to see whether tumour rates rise.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSulfoxide and sulfone\u003c\/strong\u003e: oxidised forms of cardarine made in the body and used as targets in doping tests.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetention time\u003c\/strong\u003e: the moment a substance emerges from a chromatography column; a sample emerging alongside its reference standard supports its identity.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/cardarine\"\u003eCardarine (GW-501516) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/rad-140\"\u003eRAD-140 (Testolone) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-imuscle\"\u003eiMuscle brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003eCardarine (GW-501516): what happened in development\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, not a food supplement and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eSprecher DL, et al. Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist. Arterioscler Thromb Vasc Biol. 2007;27(2):359-65. PMID: 17110604.\u003c\/li\u003e\n\u003cli\u003eMiller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-9. PMID: 24900290.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. PMID: 34565686.\u003c\/li\u003e\n\u003cli\u003eThevis M, et al. Characterization of two major urinary metabolites of the PPARdelta-agonist GW1516 and implementation of the drug in routine doping controls. Anal Bioanal Chem. 2010;396(7):2479-91. PMID: 19946680.\u003c\/li\u003e\n\u003cli\u003eBarbara M, et al. Drug-Induced Liver Injury Associated With Alpha Bolic (RAD-140) and Alpha Elite (RAD-140 and LGD-4033). ACG Case Rep J. 2020;7(6):e00409. PMID: 33062783.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468979089634,"sku":null,"price":89.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/Combo10_1c630ed1-3aaf-4e68-872f-dc9700010877.jpg?v=1789931403"},{"product_id":"imuscle-ligandrol-ibutamoren-ostarine","title":"iMuscle Ligandrol + Ibutamoren + Ostarine stack","description":"\u003cp\u003eThe iMuscle Ligandrol, Ibutamoren and Ostarine bundle groups three iMuscle research compounds in one listing: ligandrol (LGD-4033), ibutamoren (MK-677) and ostarine (MK-2866). Two are SARMs and one is a growth hormone secretagogue. iMuscle lists the pack as 60 capsules and states no per-capsule strength, so we do not invent one. Supplied to adults for laboratory research only, not for human consumption.\u003c\/p\u003e\n\u003cp\u003eA bundle is a listing convenience only: it lets separately packaged products from one manufacturer be ordered in a single purchase. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product. Each compound is described in turn.\u003c\/p\u003e\n\u003ch2\u003eThis listing\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: iMuscle (third-party brand, Muscle Market)\u003c\/li\u003e\n\u003cli\u003eCompounds: ligandrol (LGD-4033), ibutamoren (MK-677), ostarine (MK-2866)\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eCOA: only where iMuscle supplies one for the batch held\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over, for laboratory research only\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eiMuscle's single-compound listings do state strengths: \u003ca href=\"\/products\/imuscle-ligandrol-lgd4033-60-8mg\"\u003eiMuscle Ligandrol LGD-4033\u003c\/a\u003e is labelled 8 mg per capsule, \u003ca href=\"\/products\/imuscle-ostarine-k2866-60-15mg\"\u003eiMuscle Ostarine MK-2866\u003c\/a\u003e 15 mg and \u003ca href=\"\/products\/imuscle-ibutamoren-mk-677-60-10mg\"\u003eiMuscle Ibutamoren MK-677\u003c\/a\u003e 10 mg, each in packs of 60 capsules. They do not apply to this bundle.\u003c\/p\u003e\n\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\n\u003ch3\u003eLigandrol (LGD-4033)\u003c\/h3\u003e\n\u003cp\u003eLigandrol (LGD-4033, VK5211, anabolicum) is a non-steroidal SARM from Ligand Pharmaceuticals. Its main published placebo-controlled human study, a 21-day trial in 76 healthy men aged 21 to 50, reported dose-dependent gains in lean body mass with no significant change in fat mass, together with dose-dependent suppression of total testosterone, SHBG, HDL cholesterol and triglycerides, which returned to baseline after the study ended (Basaria 2013). It was never approved. WADA class S1. Compare brands on the \u003ca href=\"\/collections\/lgd-4033\"\u003eLigandrol (LGD-4033) collection page\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eMK-677 (Ibutamoren)\u003c\/h3\u003e\n\u003cp\u003eIbutamoren (MK-677, L-163,191, nutrobal) is not a SARM but an orally active ghrelin receptor (GHS-R1a) agonist, a growth hormone secretagogue. It has more human trial data than most compounds in this category. A two-year randomised trial in 65 healthy adults aged 60 to 81 reported, at its one-year primary analysis, sustained rises in growth hormone and IGF-1, about 1 kg more fat-free mass than placebo and no gain in strength or function, alongside increased appetite, mild fluid retention, muscle pain, higher fasting glucose and reduced insulin sensitivity (Nass 2008). Never approved. WADA class S2. Compare brands on the \u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection page\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eOstarine (MK-2866, enobosarm)\u003c\/h3\u003e\n\u003cp\u003eOstarine (MK-2866, enobosarm, GTx-024) is a non-steroidal selective androgen receptor modulator developed for muscle wasting, and the most clinically studied SARM. A 2011 phase II trial in healthy older adults reported more lean body mass than placebo over twelve weeks and a change in one physical function measure, with dose-related falls in HDL cholesterol and suppression of total testosterone in men (Dalton 2011). Later phase III trials in patients with cancer-related muscle wasting did not lead to approval, and it is not licensed anywhere. WADA class S1. Compare brands on the \u003ca href=\"\/collections\/ostarine\"\u003eOstarine (MK-2866, enobosarm) collection page\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eChemical identity of each compound\u003c\/h3\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCompound\u003c\/th\u003e\n\u003cth\u003ePubChem CID\u003c\/th\u003e\n\u003cth\u003eCAS number\u003c\/th\u003e\n\u003cth\u003eFormula\u003c\/th\u003e\n\u003cth\u003eMolecular weight\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eLigandrol (LGD-4033)\u003c\/td\u003e\n\u003ctd\u003e44137686\u003c\/td\u003e\n\u003ctd\u003e1165910-22-4\u003c\/td\u003e\n\u003ctd\u003eC14H12F6N2O\u003c\/td\u003e\n\u003ctd\u003e338.25\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIbutamoren (MK-677), free base\u003c\/td\u003e\n\u003ctd\u003e178024\u003c\/td\u003e\n\u003ctd\u003e159634-47-6\u003c\/td\u003e\n\u003ctd\u003eC27H36N4O5S\u003c\/td\u003e\n\u003ctd\u003e528.7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOstarine (enobosarm)\u003c\/td\u003e\n\u003ctd\u003e11326715\u003c\/td\u003e\n\u003ctd\u003e841205-47-8\u003c\/td\u003e\n\u003ctd\u003eC19H14F3N3O3\u003c\/td\u003e\n\u003ctd\u003e389.3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eThese summaries report what was measured in trial participants, each compound studied separately. No published study has examined the three together, and none of it is a claim about the capsules in this bundle.\u003c\/p\u003e\n\u003ch2\u003eLigandrol, ibutamoren and ostarine in the UK: buying, legal status and what to check\u003c\/h2\u003e\n\u003cp\u003eTwo questions matter here: may these compounds change hands in Britain, and how does a checkable listing differ from one taken on trust?\u003c\/p\u003e\n\u003ch3\u003eThe legal position for each compound\u003c\/h3\u003e\n\u003cp\u003eNone of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement. At the time of writing, none of the three is controlled under the Misuse of Drugs Act 1971. Free Muscle supplies them to adults aged 18 and over for laboratory research only. They are not for human consumption. LGD-4033 and ostarine fall under WADA class S1; MK-677 is listed under S2. For ibutamoren, see our \u003ca href=\"\/pages\/mk-677-legal-status-uk\"\u003eMK-677 legal status page\u003c\/a\u003e. Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e covers the class.\u003c\/p\u003e\n\u003ch3\u003eWhy these three names attract scrutiny\u003c\/h3\u003e\n\u003cp\u003eOver five years, the falsified medicines working group of the European network of official medicines control laboratories, whose members include the MHRA laboratory in London, collected results on 324 samples from 14 laboratories in 13 countries (Barrios 2025). Ibutamoren, ligandrol and ostarine headed the list of the five molecules reported most often, and about a quarter of products had been presented as dietary supplements, which the authors noted leaves buyers unaware that a pharmaceutical substance is inside.\u003c\/p\u003e\n\u003cp\u003eLabels are the other problem. Of 44 products bought online as SARMs in 2016, only 23 contained a SARM at all, while 17 held a different unapproved drug, ibutamoren among them, and only 18 matched the amount on their label (Van Wagoner 2017). For a pack naming three compounds, each name is a separate claim needing its own evidence.\u003c\/p\u003e\n\u003ch3\u003eWhat a checkable UK listing shows\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eA stated amount per capsule for each compound.\u003c\/li\u003e\n\u003cli\u003eA printed batch number matching a certificate that covers every compound.\u003c\/li\u003e\n\u003cli\u003eA named UK seller, an 18+ restriction, plain packaging and tracked delivery.\u003c\/li\u003e\n\u003cli\u003eNo directions for human use and no promised outcomes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis bundle meets the seller-side points: it is sold and dispatched by FreeMuscle LTD in Scunthorpe, with free tracked UK delivery in plain packaging, same-day processing for orders placed before 2pm Monday to Friday, EU delivery in three to seven working days, and 30-day returns on unopened items (\u003ca href=\"\/pages\/shipping\"\u003edelivery\u003c\/a\u003e, \u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e). It fails the strength point, because iMuscle states none. See our \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\n\u003cp\u003eAll three compounds are also sold as liquids, tablets and powder. No study has compared formats for any of them, so the useful comparison concerns measurement, not effect.\u003c\/p\u003e\n\u003cp\u003eA capsule fixes its quantity once, at filling, before the container is sealed. A laboratory can then report milligrams per capsule directly. The weakness is variation between capsules, which depends on how evenly the powder was mixed and which a single averaged assay cannot show. A liquid fixes only a concentration. Every later portion depends on the measuring device and on solvent not evaporating from a bottle opened many times. Loose powder fixes nothing in advance and relies wholly on the balance used to weigh it.\u003c\/p\u003e\n\u003cp\u003eAll three are small synthetic molecules, not peptides, so the argument that swallowed peptides are largely digested, discussed in \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e, does not apply in the same way; each trial cited above gave the compound by mouth. One point is specific to ibutamoren: it is often sold as its mesylate salt, which weighs more than the free base in the table above, so any stated amount should say which form it counts. None of this is a claim about what a capsule does.\u003c\/p\u003e\n\u003ch2\u003eLigandrol, ostarine and MK-677 compared with RAD-140\u003c\/h2\u003e\n\u003cp\u003eRAD-140 (testolone) is not in this pack but is the compound most often compared with ligandrol, so it is included for reference.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint\u003c\/th\u003e\n\u003cth\u003eLigandrol\u003c\/th\u003e\n\u003cth\u003eOstarine\u003c\/th\u003e\n\u003cth\u003eMK-677\u003c\/th\u003e\n\u003cth\u003eRAD-140 (not in this pack)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eClass\u003c\/td\u003e\n\u003ctd\u003eNon-steroidal SARM\u003c\/td\u003e\n\u003ctd\u003eNon-steroidal SARM\u003c\/td\u003e\n\u003ctd\u003eNon-peptide growth hormone secretagogue\u003c\/td\u003e\n\u003ctd\u003eNon-steroidal SARM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTarget\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor\u003c\/td\u003e\n\u003ctd\u003eGhrelin receptor (GHS-R1a)\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOriginal developer\u003c\/td\u003e\n\u003ctd\u003eLigand Pharmaceuticals\u003c\/td\u003e\n\u003ctd\u003eGTx\u003c\/td\u003e\n\u003ctd\u003eMerck\u003c\/td\u003e\n\u003ctd\u003eRadius Health\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMain published human data\u003c\/td\u003e\n\u003ctd\u003e21-day trial in 76 healthy men\u003c\/td\u003e\n\u003ctd\u003ePhase II trial in older adults; phase III trials in cancer patients\u003c\/td\u003e\n\u003ctd\u003eTwo-year randomised trial in 65 older adults\u003c\/td\u003e\n\u003ctd\u003eOne phase 1 trial in women with advanced breast cancer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLicensed anywhere\u003c\/td\u003e\n\u003ctd\u003eNo\u003c\/td\u003e\n\u003ctd\u003eNo\u003c\/td\u003e\n\u003ctd\u003eNo\u003c\/td\u003e\n\u003ctd\u003eNo\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA section\u003c\/td\u003e\n\u003ctd\u003eS1, anabolic agents\u003c\/td\u003e\n\u003ctd\u003eS1, anabolic agents\u003c\/td\u003e\n\u003ctd\u003eS2, growth hormone secretagogues\u003c\/td\u003e\n\u003ctd\u003eS1, anabolic agents\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eMK-2866 and MK-677 share only a development-code prefix, not a mechanism. Ostarine acts at the androgen receptor, the same target as testosterone. MK-677 never touches that receptor; it imitates ghrelin, prompting the pituitary to release growth hormone, which in turn raises IGF-1. Its recorded adverse findings on glucose, fluid and appetite reflect that different pathway.\u003c\/p\u003e\n\u003cp\u003eLigandrol and ostarine do share a target, and both trials recorded falls in testosterone and HDL cholesterol. The difference is the record: ostarine was taken through larger and longer trials in older adults and cancer patients, ligandrol, in the published record, mainly through one three-week study in healthy men. No trial compared them directly, so claims that one is stronger or milder rest on anecdote.\u003c\/p\u003e\n\u003cp\u003eRAD-140 is a third androgen receptor ligand, from a different chemical family. Its only clinical trial studied tolerability in cancer, where raised liver enzymes were frequent; our \u003ca href=\"\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 research summary\u003c\/a\u003e gives the detail. RAD-140 brands are compared on the \u003ca href=\"\/collections\/rad-140\"\u003eRAD-140 (Testolone) collection page\u003c\/a\u003e, and ibutamoren's nearest peptide counterpart is covered in \u003ca href=\"\/blogs\/news\/mk-677-vs-ipamorelin-vs-hgh\"\u003eMK-677 vs ipamorelin vs somatropin\u003c\/a\u003e. Nothing here ranks one compound above another.\u003c\/p\u003e\n\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\n\u003cp\u003eAny certificate for this pack comes from iMuscle, not from us. We show one only when iMuscle has supplied it for the precise batch on our shelves, and if nothing is shown, nothing has been supplied; a generic document never stands in. Janoshik Analytical testing of every batch, with certificates emailed on request, applies to Free Muscle-brand products only.\u003c\/p\u003e\n\u003cp\u003eThree compounds mean three identities to prove. Check each field:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number.\u003c\/strong\u003e Compare it character by character with the lot printed on your pack; a near miss is a different lot.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity.\u003c\/strong\u003e HPLC compares a sample's peak with a reference standard; LC-MS adds a measured mass that should fit the formulas in the table above. Each compound needs its own result; one confirmed compound says nothing of the other two.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStereochemistry.\u003c\/strong\u003e Ligandrol has two stereocentres and ostarine one, so mirror-image forms share their formula and mass. Only a chiral method separates them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e Normally reported as a percentage of chromatogram peak area. A figure of 99 per cent describes the proportion of what was detected, never the milligrams inside a capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e With no stated strength, this measured figure would be the only statement of quantity for this bundle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest date and laboratory.\u003c\/strong\u003e A named laboratory can confirm a report at source.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eA missing field has a specific meaning here. No certificate for the batch in stock means nothing independent confirms which compounds are present. Identity results without content figures confirm presence, not amount. Email us through the \u003ca href=\"\/pages\/contact\"\u003econtact page\u003c\/a\u003e with the product name and batch number and we will send what we hold, or say plainly that there is none. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e explain the methods.\u003c\/p\u003e\n\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\n\u003cp\u003eAll three compounds are prohibited at all times, in and out of competition, on the WADA Prohibited List, which UK Anti-Doping applies in the UK. Ligandrol and ostarine are named in section S1, anabolic agents; ibutamoren falls under section S2 as a growth hormone secretagogue. Under strict liability an athlete answers for any prohibited substance in their sample, whatever its source.\u003c\/p\u003e\n\u003cp\u003eAccredited anti-doping laboratories screen routinely for ligandrol and ostarine, and both have been the subject of published excretion studies using microgram amounts, summarised on the single-compound pages for \u003ca href=\"\/products\/imuscle-ligandrol-lgd4033-60-8mg\"\u003eiMuscle LGD-4033\u003c\/a\u003e and \u003ca href=\"\/products\/imuscle-ostarine-k2866-60-15mg\"\u003eiMuscle Ostarine\u003c\/a\u003e. Those studies set no upper limit and none used capsules like these. Ibutamoren is also within the scope of testing. A blood half-life is no guide to detection, because laboratories also target long-lived metabolites. For every compound in this bundle the accurate statement is: detectable, window not established. Anyone bound by an anti-doping code should treat this product as prohibited.\u003c\/p\u003e\n\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\n\u003cp\u003eNo published shelf-life study covers ligandrol, ibutamoren or ostarine in capsule form, so no shelf life is quoted here beyond any expiry date iMuscle prints. A certificate describes a batch only on its test date.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep every container as supplied.\u003c\/strong\u003e The lot number on each pot is its only link to a certificate, and loose capsules can look identical.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCool, dry and dark.\u003c\/strong\u003e A closed cupboard away from heat and sunlight. Close the lid after each opening and leave any desiccant inside.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep a log.\u003c\/strong\u003e Record the date received and the date each seal was broken beside the lot number, and label any sample drawn for analysis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInspect before use in the lab.\u003c\/strong\u003e Capsules that have clumped, softened or changed colour should be quarantined and reported to us with the lot number.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreat it as bench material.\u003c\/strong\u003e Use gloves once a container is open, keep the work area free of food and drink, store it where children and pets cannot reach, and send surplus to chemical waste under local rules.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eReturns within 30 days apply to unopened items only.\u003c\/p\u003e\n\u003ch2\u003eGlossary\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: short for selective androgen receptor modulator. Two of the three compounds here qualify; ibutamoren sits in a different class altogether.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth hormone secretagogue\u003c\/strong\u003e: any substance that prompts the pituitary gland to release growth hormone; ibutamoren belongs to this class.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGhrelin and GHS-R1a\u003c\/strong\u003e: ghrelin is a hormone made mainly in the stomach; GHS-R1a is its receptor, which ibutamoren activates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIGF-1\u003c\/strong\u003e: insulin-like growth factor 1, produced largely by the liver in response to growth hormone and measured as a marker of that axis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSHBG\u003c\/strong\u003e: the carrier protein that binds testosterone in blood; it fell in a dose-dependent manner in the 2013 LGD-4033 study.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCachexia\u003c\/strong\u003e: wasting of muscle and body weight in serious illness such as cancer; enobosarm's late-stage trials enrolled patients with it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMesylate\u003c\/strong\u003e: the methanesulfonate salt in which ibutamoren is commonly supplied; a milligram of salt holds less than a milligram of free base.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStereocentre\u003c\/strong\u003e: a point in a molecule where two mirror-image arrangements are possible, giving isomers of identical mass.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: the anti-doping principle that a prohibited substance in a sample counts against the athlete regardless of intent.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRelated\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/lgd-4033\"\u003eLGD-4033 (Ligandrol) collection\u003c\/a\u003e and the \u003ca href=\"\/blogs\/news\/lgd-4033-ligandrol-research-guide\"\u003eligandrol research guide\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/mk-677-ibutamoren-what-the-research-says\"\u003eMK-677 (ibutamoren): what the research says\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/ostarine\"\u003eOstarine (MK-2866) collection\u003c\/a\u003e and the \u003ca href=\"\/blogs\/news\/ostarine-mk-2866-research-guide\"\u003eostarine research guide\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-imuscle\"\u003eiMuscle brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eBasaria S, et al. The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci. 2013;68(1):87-95. PMID: 22459616.\u003c\/li\u003e\n\u003cli\u003eNass R, et al. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008;149(9):601-11. PMID: 18981485.\u003c\/li\u003e\n\u003cli\u003eDalton JT, et al. The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial. J Cachexia Sarcopenia Muscle. 2011;2(3):153-161. PMID: 22031847.\u003c\/li\u003e\n\u003cli\u003eBarrios MM, et al. SARMs, Metabolic Modulators and Growth Hormone Secretagogues in Suspected Illegal Medicines, Bought as Sport Performance Enhancers: A Retro- and Prospective Study Within the GEON. Drug Test Anal. 2025;17(10):2078-2085. PMID: 40551438.\u003c\/li\u003e\n\u003cli\u003eVan Wagoner RM, et al. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004-2010. PMID: 29183075.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468979646690,"sku":null,"price":120.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/Combo2_720x_63c30469-21b1-4273-b023-bbca00a0d09a.jpg?v=1789931408"},{"product_id":"imuscle-ligandrol-testolon-yk-11","title":"iMuscle Ligandrol + Testolone + YK-11 stack","description":"\u003cp\u003eThe iMuscle Ligandrol, Testolone and YK-11 bundle places three androgen receptor compounds from one manufacturer in a single listing: ligandrol (LGD-4033), testolone (RAD-140) and YK-11. iMuscle lists the pack as 60 capsules and does not state a strength per capsule, so none is quoted here. Like every product on Free Muscle, it is supplied to adults for laboratory research only and is not for human consumption.\u003c\/p\u003e\u003cp\u003eA bundle is a listing convenience only: it lets separately packaged products from one manufacturer be ordered in a single purchase. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: iMuscle (third-party brand, \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e)\u003c\/li\u003e\n\u003cli\u003eCompounds: ligandrol (LGD-4033), testolone (RAD-140), YK-11\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: not stated by the manufacturer for any of the three, so no per-capsule or per-pack total is given\u003c\/li\u003e\n\u003cli\u003eCOA: only where iMuscle supplies one for the batch held\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over, for laboratory research only\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWhere a stated strength matters for a research record, iMuscle's single-compound listings carry one on the label: \u003ca href=\"\/products\/imuscle-ligandrol-lgd4033-60-8mg\"\u003eiMuscle Ligandrol LGD-4033\u003c\/a\u003e at 8 mg per capsule, \u003ca href=\"\/products\/imuscle-testolon-rad-140-60-10mg\"\u003eiMuscle Testolone RAD-140\u003c\/a\u003e at 10 mg and \u003ca href=\"\/products\/imuscle-yk-11-60-10mg\"\u003eiMuscle YK-11\u003c\/a\u003e at 10 mg, each in packs of 60.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eLigandrol (LGD-4033)\u003c\/h3\u003e\u003cp\u003eLigandrol (LGD-4033, VK5211, anabolicum) is a non-steroidal SARM from Ligand Pharmaceuticals (PubChem CID 44137686, CAS 1165910-22-4, formula C14H12F6N2O, molecular weight 338.25). The only published placebo-controlled human study, a 21-day phase I trial in 76 healthy young men, reported a dose-dependent rise in lean body mass with no significant change in fat mass, together with dose-dependent falls in total testosterone, SHBG, HDL cholesterol and triglycerides, which returned to baseline after stopping (Basaria 2013). It was never approved. WADA class S1. Compare brands on the \u003ca href=\"\/collections\/lgd-4033\"\u003eLigandrol (LGD-4033) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eTestolone (RAD-140)\u003c\/h3\u003e\u003cp\u003eTestolone (RAD-140, vosilasarm) is a non-steroidal SARM designed by Radius Health and characterised in rats and non-human primates (Miller 2011; PubChem CID 44200882, CAS 1182367-47-0, formula C20H16ClN5O2, molecular weight 393.8). Human data are limited to a small early oncology study. That first-in-human phase 1 trial recruited 22 postmenopausal women with ER-positive, HER2-negative metastatic breast cancer and gave the compound by mouth. Liver findings led its adverse-event list, with AST raised in 59.1 per cent of participants, ALT in 45.5 per cent and bilirubin in 27.3 per cent, and 16 women had at least one grade 3 or 4 event (LoRusso 2022). It assessed tolerability and tumour response, not muscle. Published case reports describe drug-induced liver injury in adults who had taken products labelled as containing RAD-140, in one case alongside LGD-4033 (Barbara 2020). It has never been approved as a medicine. WADA class S1. Compare brands on the \u003ca href=\"\/collections\/rad-140\"\u003eTestolone (RAD-140) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eYK-11\u003c\/h3\u003e\u003cp\u003eYK-11 is a steroidal compound, structurally unlike the other SARMs here (PubChem CID 119058028, CAS 1370003-76-1, formula C25H34O6, molecular weight 430.5). In a 2011 reporter-gene study it behaved as a partial androgen receptor agonist in cultured cells (Kanno 2011). Most later work is also in cells. A 2023 study in male rats reported raised oxidative stress and impaired mitochondrial markers in the hippocampus after five weeks of exposure (Dahleh 2023). There is no formal toxicology programme, no human data and no clinical development. WADA class S1. Compare brands on the \u003ca href=\"\/collections\/yk-11\"\u003eYK-11 collection page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eEvery study above looked at one compound on its own. Nothing has been published on LGD-4033, RAD-140 and YK-11 in combination, and none of these findings is a claim about this product.\u003c\/p\u003e\u003ch2\u003eLGD-4033, RAD-140 and YK-11 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003ch3\u003eThe legal position\u003c\/h3\u003e\u003cp\u003eNone of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement, so none may lawfully be sold for human consumption. Free Muscle supplies them to adults aged 18 and over for laboratory research only.\u003c\/p\u003e\u003cp\u003eLGD-4033 and RAD-140 are non-steroidal and, at the time of writing, are not controlled drugs in the UK. YK-11 needs a closer look. Its carbon skeleton is that of a steroid, and anabolic steroids are Class C controlled drugs in the UK, so its position is less settled than that of the other two. Anyone ordering is responsible for the rules that apply to them and their institution. All three compounds fall under WADA class S1 (anabolic agents). Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e has more background.\u003c\/p\u003e\u003ch3\u003eWhat a trustworthy UK listing shows\u003c\/h3\u003e\u003cp\u003eThese points separate a documented product from an undocumented one:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eA stated amount of every compound per capsule, so that a certificate has a figure to be checked against.\u003c\/li\u003e\n\u003cli\u003eA batch or lot number printed on the pot, matching the number on the certificate.\u003c\/li\u003e\n\u003cli\u003eA certificate for that batch that covers each compound named on the label, not only the first one.\u003c\/li\u003e\n\u003cli\u003eA named UK company with an address, and an 18+ restriction at checkout.\u003c\/li\u003e\n\u003cli\u003ePlain packaging and tracked delivery.\u003c\/li\u003e\n\u003cli\u003eNo instructions for taking the product and no outcome photographs or promises.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eHow this listing compares\u003c\/h3\u003e\u003cp\u003eMeasured against that list, this bundle falls short on the first point: iMuscle gives no strength, and we will not invent one. A certificate appears only where iMuscle supplies one for the batch in stock. The remaining points are met by us as the seller. FreeMuscle LTD is a UK company based in Scunthorpe; UK delivery is free, tracked and in plain packaging; orders placed before 2pm Monday to Friday are processed the same working day; EU delivery takes 3 to 7 working days; and unopened items can be returned within 30 days. Details are on the \u003ca href=\"\/pages\/shipping\"\u003eshipping page\u003c\/a\u003e and the \u003ca href=\"\/pages\/guarantee\"\u003eguarantee page\u003c\/a\u003e, and our \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e sets out each check in more depth.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eAll three compounds circulate as capsules, tablets and liquids, and \"YK11 injectable\" and \"RAD 140 liquid UK\" are both common searches. No published study has compared these formats for LGD-4033, RAD-140 or YK-11, so the useful differences are about measurement and keeping the material intact, not about effect.\u003c\/p\u003e\u003cp\u003eIn a capsule the amount is fixed at the filling stage, and a content assay of finished capsules can then confirm it. That only works if a target figure exists, which is exactly what this bundle lacks. The listing also does not break the 60 capsules down by compound, so if the split matters to your records, ask us before ordering. A liquid is labelled in milligrams per millilitre; its accuracy then rests on how exactly volumes are measured, whether the compound stays in solution, and whether solvent evaporates from a bottle opened many times, which concentrates what is left.\u003c\/p\u003e\u003cp\u003eNone of the three is a peptide. They are small synthetic molecules, so the objection raised against swallowed peptides, that digestive enzymes break them down (see \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e), does not apply in the same way. Both published human trials in this family, for LGD-4033 and for RAD-140, gave the compound by mouth. We are aware of no published human study of any of the three given by injection, and YK-11 has never been given to people in a published study at all.\u003c\/p\u003e\u003ch2\u003eLigandrol compared with ostarine\u003c\/h2\u003e\u003cp\u003eRAD-140 is already covered above, so this section sets ligandrol beside ostarine, a compound not in this bundle.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint\u003c\/th\u003e\n\u003cth\u003eLigandrol (LGD-4033)\u003c\/th\u003e\n\u003cth\u003eOstarine (MK-2866)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOther names\u003c\/td\u003e\n\u003ctd\u003eVK5211, anabolicum\u003c\/td\u003e\n\u003ctd\u003eEnobosarm, GTx-024\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDeveloper\u003c\/td\u003e\n\u003ctd\u003eLigand Pharmaceuticals\u003c\/td\u003e\n\u003ctd\u003eGTx, Inc.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and molecular weight\u003c\/td\u003e\n\u003ctd\u003eC14H12F6N2O, 338.25\u003c\/td\u003e\n\u003ctd\u003eC19H14F3N3O3, 389.3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e1165910-22-4\u003c\/td\u003e\n\u003ctd\u003e841205-47-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTarget\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKey published human trial\u003c\/td\u003e\n\u003ctd\u003e21-day phase I, 76 healthy young men\u003c\/td\u003e\n\u003ctd\u003e12-week phase II, 120 men over 60 and postmenopausal women\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMain recorded findings\u003c\/td\u003e\n\u003ctd\u003eLean body mass rose with dose; fat mass unchanged; testosterone, SHBG and HDL fell\u003c\/td\u003e\n\u003ctd\u003eLean body mass rose with dose versus placebo; adverse events at similar rates across groups\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eApproved as a medicine\u003c\/td\u003e\n\u003ctd\u003eNo\u003c\/td\u003e\n\u003ctd\u003eNo\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA class\u003c\/td\u003e\n\u003ctd\u003eS1, anabolic agents\u003c\/td\u003e\n\u003ctd\u003eS1, anabolic agents\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eBoth are non-steroidal and both target the androgen receptor, but they come from different chemical families: ligandrol is built on a fluorinated pyrrolidine ring, while ostarine is an aryl-propionamide with two cyano groups. The trials also asked different questions. The ligandrol study was short and in young men, and its main purpose was tolerability and pharmacokinetics. The ostarine study ran four times longer, in older adults, and was sponsored and run by the developer, which also reported changes in a physical function measure and in insulin resistance (Dalton 2011). Neither trial was designed to show long-term safety, and neither compound has been approved anywhere. Nothing here ranks one compound above the other.\u003c\/p\u003e\u003cp\u003eOstarine brands are compared on the \u003ca href=\"\/collections\/ostarine\"\u003eostarine collection page\u003c\/a\u003e and the \u003ca href=\"\/blogs\/news\/ostarine-mk-2866-research-guide\"\u003eostarine research guide\u003c\/a\u003e covers its trials. For testolone the comparison searched most often is with RAD-150, the benzoate ester sold as TLB-150; see the \u003ca href=\"\/collections\/rad-150\"\u003eRAD-150 collection\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eiMuscle is a third-party brand sold through Muscle Market. For third-party brands we display a certificate of analysis only where the manufacturer supplies one for the exact batch we hold; if none is shown, none has been supplied and we do not substitute a generic document. Free Muscle-brand products, by contrast, are assayed batch by batch at Janoshik Analytical, with the certificate sent on request by email. That Janoshik testing does not extend to iMuscle.\u003c\/p\u003e\u003cp\u003eIf a certificate is available for this bundle, read it field by field:\u003c\/p\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number.\u003c\/strong\u003e Compare it character by character with the lot code on your pot; the certificate only speaks for that lot.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity.\u003c\/strong\u003e HPLC compares the retention time of each peak with a reference standard; LC-MS adds a mass reading. The expected molecular weights are 338.25 for LGD-4033, 393.8 for RAD-140 and 430.5 for YK-11. Each compound should have its own result.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e Usually given as the percentage of total peak area on the HPLC trace. With three compounds, check that each is reported separately and that any unknown peaks are listed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent.\u003c\/strong\u003e Milligrams found per capsule. For this listing this would be the only figure anywhere stating how much of each compound is present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory and test date.\u003c\/strong\u003e A named laboratory and a date let the result be traced at source and show how old it is.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003eA gap on the certificate has a plain meaning here. No certificate for the batch held means nothing independent confirms what the capsules contain. A certificate naming only ligandrol says nothing about testolone or YK-11. Identity without content confirms that a compound is present but not how much. To ask for what we hold, email us via the \u003ca href=\"\/pages\/contact\"\u003econtact page\u003c\/a\u003e with the product name and batch number. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e and the guide on \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e explain the methods further.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eLGD-4033, RAD-140 and YK-11 are all on the WADA Prohibited List under S1, anabolic agents, and are banned at all times, in and out of competition. UK Anti-Doping applies that list in the UK. Anti-doping rules work on strict liability: a prohibited substance found in an athlete's sample counts against them regardless of how it got there or what the product label said, so anyone subject to testing should treat this bundle as prohibited.\u003c\/p\u003e\u003cp\u003eAccredited laboratories screen for SARMs and for their urinary metabolites, not only the parent compound. For that reason a blood half-life, such as the 44.7 hours measured for RAD-140 in the oncology trial (LoRusso 2022), is not a detection window. This page cites no study that sets a detection window for any of the three, so the accurate answer for each is: detectable, window not established.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eNo stability study has been published for capsules of LGD-4033, RAD-140 or YK-11, so we give no shelf life beyond any date iMuscle prints on the pack. What can be controlled is exposure to heat, humidity and light.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eKeep the pots sealed, at cool room temperature, in a dry cupboard away from sunlight and radiators.\u003c\/li\u003e\n\u003cli\u003eOpen one pot at a time, reseal it promptly, and keep any moisture-absorbing sachet in with the capsules.\u003c\/li\u003e\n\u003cli\u003eDo not decant capsules into other containers; once separated from the labelled pot they can no longer be tied to a batch number or certificate.\u003c\/li\u003e\n\u003cli\u003eIf shells turn soft, split or change colour, quarantine that pot and send us the batch number.\u003c\/li\u003e\n\u003cli\u003eWear gloves when handling, keep the pots well clear of kitchens, children and pets, and send surplus material for disposal as laboratory chemical waste.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator, a compound designed to activate the androgen receptor in some tissues more than others.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePartial agonist\u003c\/strong\u003e: a compound that activates a receptor but produces a weaker maximum response than the body's own hormone, as reported for YK-11 in cells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLean body mass\u003c\/strong\u003e: body weight minus fat, usually measured by a DEXA scan; the main outcome in the ligandrol and ostarine trials.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSHBG\u003c\/strong\u003e: sex hormone-binding globulin, a blood protein that carries testosterone; it fell in the ligandrol trial.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHDL cholesterol\u003c\/strong\u003e: the lipoprotein fraction usually regarded as protective, which also fell in the ligandrol trial.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAST and ALT\u003c\/strong\u003e: liver enzymes that rise in the blood when liver cells are damaged.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhase I and phase II\u003c\/strong\u003e: early clinical trial stages that test tolerability and first signs of an effect, not long-term safety.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC\u003c\/strong\u003e: high-performance liquid chromatography; a sample is pushed through a packed column and its components emerge at different times as separate peaks.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLC-MS\u003c\/strong\u003e: a chromatography run coupled to a mass spectrometer, so each separated peak also gets a measured mass, a stronger identity check than retention time alone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWADA S1\u003c\/strong\u003e: the anabolic agents section of the World Anti-Doping Agency Prohibited List.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/lgd-4033\"\u003eLGD-4033 (Ligandrol) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/rad-140\"\u003eRAD-140 (Testolone) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/yk-11\"\u003eYK-11 collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/ostarine\"\u003eOstarine (MK-2866) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/brand-imuscle\"\u003eiMuscle brand page\u003c\/a\u003e and \u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/lgd-4033-ligandrol-research-guide\"\u003eLGD-4033 (ligandrol) research guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/yk-11-what-is-known\"\u003eYK-11: what is known\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eBasaria S, et al. The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci. 2013;68(1):87-95. PMID: 22459616.\u003c\/li\u003e\n\u003cli\u003eMiller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-9. PMID: 24900290.\u003c\/li\u003e\n\u003cli\u003eKanno Y, et al. (17alpha,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11) is a partial agonist of the androgen receptor. Biol Pharm Bull. 2011;34(3):318-23. PMID: 21372378.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. PMID: 34565686.\u003c\/li\u003e\n\u003cli\u003eDalton JT, et al. The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial. J Cachexia Sarcopenia Muscle. 2011;2(3):153-61. PMID: 22031847.\u003c\/li\u003e\n\u003cli\u003eBarbara M, et al. Drug-Induced Liver Injury Associated With Alpha Bolic (RAD-140) and Alpha Elite (RAD-140 and LGD-4033). ACG Case Rep J. 2020;7(6):e00409. PMID: 33062783.\u003c\/li\u003e\n\u003cli\u003eDahleh MMM, et al. YK11 induces oxidative stress and mitochondrial dysfunction in hippocampus: The interplay between a selective androgen receptor modulator (SARM) and exercise. J Steroid Biochem Mol Biol. 2023;233:106364. PMID: 37468001.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468979843298,"sku":null,"price":119.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/Combo5_7fdb5057-d6a3-4b23-a7bb-b8cc28b4f448.jpg?v=1789931410"},{"product_id":"imuscle-ostarine-andarine-cardarine","title":"iMuscle Ostarine + Andarine + Cardarine stack","description":"\u003cp\u003eThe iMuscle Ostarine, Andarine and Cardarine bundle groups three research compounds from one manufacturer into a single listing: ostarine (MK-2866), andarine (S-4) and cardarine (GW-501516). iMuscle lists the pack as 60 capsules and does not state a strength per capsule, so we do not quote one. Supplied to adults for laboratory research only, not for human consumption.\u003c\/p\u003e\u003cp\u003eA bundle is a listing convenience only: it lets separately packaged products from one manufacturer be ordered in a single purchase. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eOstarine (MK-2866, enobosarm)\u003c\/h3\u003e\u003cp\u003eOstarine (MK-2866, enobosarm, GTx-024) is a non-steroidal selective androgen receptor modulator developed for muscle wasting, and one of the most clinically studied SARMs. A 2011 phase II trial in healthy older adults reported more lean body mass than placebo over twelve weeks, alongside dose-related falls in HDL cholesterol and, in men, lower SHBG and total testosterone. Phase III cancer cachexia trials reported lean mass gains but missed their physical function endpoints, and it was never approved. WADA class S1. Compare brands on the \u003ca href=\"\/collections\/ostarine\"\u003eOstarine (MK-2866, enobosarm) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eAndarine (S-4)\u003c\/h3\u003e\u003cp\u003eAndarine (S-4, GTx-007) is an earlier aryl-propionamide SARM from the same programme as ostarine. Its evidence is preclinical: in ovariectomised rats it prevented bone loss and reduced body fat in a 2007 study. No controlled human trial has been published and no regulator has approved it. WADA class S1. Compare brands on the \u003ca href=\"\/collections\/andarine\"\u003eAndarine (S-4) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eCardarine (GW-501516)\u003c\/h3\u003e\u003cp\u003eCardarine (GW-501516, endurobol) is not a SARM but an agonist at the PPAR-delta nuclear receptor, which regulates fatty-acid oxidation genes. In a small two-week 2007 study of 24 healthy volunteers, HDL cholesterol rose relative to placebo and fat clearance after a test meal improved, while fasting triglycerides only trended lower. Development was later discontinued after long-term rodent toxicology studies reportedly found tumours in several organs, a sponsor-reported finding that ended further human work. Never approved; prohibited by WADA as a metabolic modulator under section S4. Compare brands on the \u003ca href=\"\/collections\/cardarine\"\u003eCardarine (GW-501516) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eThese summaries describe what was measured in trial participants and laboratory animals. None of it is a claim about the capsules in this bundle.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: iMuscle (third-party brand, Muscle Market)\u003c\/li\u003e\n\u003cli\u003eCompounds: ostarine (MK-2866), andarine (S-4), cardarine (GW-501516)\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eCOA: only where iMuscle supplies one for the batch held\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOstarine, andarine and cardarine in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"ostarine UK buy\", \"cardarine UK legal\" and \"andarine UK\" reduce to two questions. Can these compounds lawfully change hands in Britain, and how can a buyer tell a checkable listing from one that asks to be taken on trust?\u003c\/p\u003e\u003ch3\u003eWhere the law stands\u003c\/h3\u003e\u003cp\u003eNone of the three appears in the schedules of the Misuse of Drugs Act 1971, so none is a controlled drug. None holds a UK marketing authorisation from the MHRA, so none may be sold or promoted as a medicine, and none is an authorised food supplement or novel food, so none may be sold for eating. What remains is supply as a chemical for laboratory research, to adults, with no directions for use and no promised outcome. That is the only basis on which Free Muscle lists this bundle. In sport the position is stricter: ostarine and andarine are prohibited at all times under WADA section S1, and cardarine under section S4.\u003c\/p\u003e\u003ch3\u003eWhy the listing matters more than the compound name\u003c\/h3\u003e\u003cp\u003eA 2017 study in \u003cem\u003eJAMA\u003c\/em\u003e bought 44 products sold online as SARMs and analysed them with methods accredited for anti-doping work (Van Wagoner et al., 2017). Only 23 contained a SARM at all. A further 17 contained another unapproved drug, among them GW501516 and SR9009; four contained no active compound; eleven held something not named on the label; and in just 18 did the measured amount match the label. The lesson for this bundle is direct: the name on a pot is a claim, and only an analysis of the lot tests it.\u003c\/p\u003e\u003ch3\u003eWhat a checkable UK listing shows, and where this one stands\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCheck\u003c\/th\u003e\n\u003cth\u003eThis bundle\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eNamed manufacturer and named seller\u003c\/td\u003e\n\u003ctd\u003eMade by iMuscle; sold and dispatched by FreeMuscle LTD, a UK company in Scunthorpe\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA stated strength for each compound\u003c\/td\u003e\n\u003ctd\u003eNot stated by the manufacturer, so none is quoted here\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA certificate tied to the lot in stock\u003c\/td\u003e\n\u003ctd\u003eShown only where iMuscle supplies one for the batch held\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNo directions for use or outcome claims\u003c\/td\u003e\n\u003ctd\u003eNone given; research use only, 18 and over\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTracked, discreet delivery\u003c\/td\u003e\n\u003ctd\u003eFree tracked UK delivery in plain packaging; orders before 2pm Monday to Friday processed the same working day; EU delivery in 3-7 working days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA returns route\u003c\/td\u003e\n\u003ctd\u003eUnopened items within 30 days, see \u003ca href=\"\/pages\/shipping\"\u003edelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThis bundle meets the seller-side checks but not the strength check, because the manufacturer has not published one; the single-compound listings in each collection are the alternative where a stated strength matters. Reviews can report delivery times, not what a capsule contains. A fuller checklist is in \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e, and the class is introduced in \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eAll three compounds are also sold as liquids and loose powders, hence searches such as \"ostarine liquid UK\". The chemistry does not change with the format; what changes is where the amount per unit is fixed and how it can be checked.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsules.\u003c\/strong\u003e The amount is set when powder is filled into shells, before the container is sealed, so a certificate can report a measured figure per capsule. Its blind spot is variation from one capsule to the next, which a pooled assay averages away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquids.\u003c\/strong\u003e The label gives a concentration, so every portion depends on the accuracy of a dropper or syringe. Solvent loss from a bottle opened often raises the concentration, and a compound held near its solubility limit can settle out in the cold. A certificate for a liquid describes the bottle only as it was when sampled.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLoose powder.\u003c\/strong\u003e Nothing is portioned in advance, so accuracy rests entirely on the balance used to weigh it.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eNone of the three is a peptide. Ostarine (molecular weight 389.3), andarine (441.4) and cardarine (453.5) are small synthetic molecules, so the usual objection to swallowed peptides, breakdown by digestive enzymes, does not apply to them in the same way; the background is in \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e. No published study compares formats for any of the three, so nothing here suggests one format works better than another. A capsule with a stated strength is simply the easiest format to verify, and this bundle lacks one.\u003c\/p\u003e\u003ch2\u003eCardarine compared with SR9009 (stenabolic)\u003c\/h2\u003e\u003cp\u003e\"Stenabolic vs cardarine\" is the comparison searched most often for the one non-SARM in this bundle. The two are often mistaken for relatives, but they act on different receptors and have very different evidence behind them.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eCardarine (in this bundle)\u003c\/th\u003e\n\u003cth\u003eSR9009\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOther names\u003c\/td\u003e\n\u003ctd\u003eGW-501516, GW1516, endurobol\u003c\/td\u003e\n\u003ctd\u003eStenabolic, SR-9009\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTarget\u003c\/td\u003e\n\u003ctd\u003ePPAR-delta, a nuclear receptor controlling genes for fatty-acid use\u003c\/td\u003e\n\u003ctd\u003eREV-ERB alpha and beta, nuclear receptors in the circadian clock\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eA drug-development programme at Glaxo Wellcome, later GlaxoSmithKline\u003c\/td\u003e\n\u003ctd\u003eA laboratory probe from the Scripps Research Institute, first described in 2012\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman data\u003c\/td\u003e\n\u003ctd\u003eSmall, short controlled studies in volunteers, including the two-week 2007 lipid study\u003c\/td\u003e\n\u003ctd\u003eNo clinical study; almost all data from injected mice and cultured cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReason development stopped\u003c\/td\u003e\n\u003ctd\u003eTumours in long-term rodent toxicology studies\u003c\/td\u003e\n\u003ctd\u003eNever entered clinical development\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLicensed as a medicine\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eS4, metabolic modulators (PPAR-delta agonists), prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eS4, metabolic modulators (listed as an example of an AMPK activator), prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThe practical difference is the depth of the record. Cardarine reached people under trial conditions, so there are measured lipid changes and a documented reason for its abandonment. SR9009 has neither: its reputation as an \"exercise mimetic\" rests on mouse work, and its oral bioavailability in humans has not been established. No study has compared the two directly. They do meet in two places. The 2017 \u003cem\u003eJAMA\u003c\/em\u003e analysis found both inside products labelled as SARMs, and both fall under the same WADA section. The development history of cardarine is covered in \u003ca href=\"\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003ecardarine: what happened in development\u003c\/a\u003e; SR9009 brands are listed in the \u003ca href=\"\/collections\/sr9009\"\u003eSR9009 collection\u003c\/a\u003e and explained in the \u003ca href=\"\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eFor the two SARMs in the bundle, the searched comparisons are \"andarine vs ostarine\" and \"ligandrol vs ostarine\". The first is set out on the \u003ca href=\"\/products\/imuscle-andarine-s4-60-15mg\"\u003eiMuscle Andarine S-4\u003c\/a\u003e page and the second on the \u003ca href=\"\/products\/imuscle-ostarine-k2866-60-15mg\"\u003eiMuscle Ostarine MK-2866\u003c\/a\u003e page, with LGD-4033 brands in the \u003ca href=\"\/collections\/lgd-4033\"\u003eLGD-4033 collection\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eiMuscle is a third-party brand, so any certificate of analysis (COA) for this bundle is the manufacturer's. We display one only where iMuscle supplies it for the exact batch we hold, and we never substitute a generic document. Free Muscle-brand products are assayed batch by batch at Janoshik Analytical, with the certificate emailed on request; that programme does not extend to iMuscle. A bundle raises one extra point: three compounds means three identities to confirm, normally on three certificates, one per lot.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCompound\u003c\/th\u003e\n\u003cth\u003eCAS\u003c\/th\u003e\n\u003cth\u003eFormula and molecular weight\u003c\/th\u003e\n\u003cth\u003eStereochemistry to check\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOstarine\u003c\/td\u003e\n\u003ctd\u003e841205-47-8\u003c\/td\u003e\n\u003ctd\u003eC19H14F3N3O3, 389.3\u003c\/td\u003e\n\u003ctd\u003eThe (2S) form; its mirror image has the same mass\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAndarine\u003c\/td\u003e\n\u003ctd\u003e401900-40-1\u003c\/td\u003e\n\u003ctd\u003eC19H18F3N3O6, 441.4\u003c\/td\u003e\n\u003ctd\u003eThe (2S) form; same issue as ostarine\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCardarine\u003c\/td\u003e\n\u003ctd\u003e317318-70-0\u003c\/td\u003e\n\u003ctd\u003eC21H18F3NO3S2, 453.5\u003c\/td\u003e\n\u003ctd\u003eNone; the molecule has no stereocentre\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eOn each certificate, look for these fields:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity.\u003c\/strong\u003e HPLC against a reference standard, or LC-MS giving a mass that fits the formula above. Without it, a purity figure could belong to a different substance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e Usually an HPLC peak-area percentage. It shows what share of the detected material is the named compound, not how many milligrams a capsule holds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e A measured milligram figure. For this bundle there is no label strength to compare it with, so the certificate would be the first statement of strength rather than a check on one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number, test date and laboratory.\u003c\/strong\u003e The lot on the certificate must match the lot on the container, and a named laboratory can be asked to confirm the report is genuine.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eIf any field is missing, the matching question stays open. \u003ca href=\"\/pages\/contact\"\u003eContact us\u003c\/a\u003e with the lot numbers and we will say what documentation exists. Further detail is in \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e and on our \u003ca href=\"\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eAll three compounds are on the WADA Prohibited List and banned in and out of competition. Ostarine and andarine sit in section S1.2, other anabolic agents. Cardarine has been on the list since January 2009, first as a gene doping substance and now in section S4 among metabolic modulators (Kintz et al., 2020). Anti-doping rules apply strict liability, so an athlete answers for any prohibited substance found in a sample whatever its source, including a mislabelled product.\u003c\/p\u003e\u003cp\u003eAccredited anti-doping laboratories screen urine for all three, and hair analysis can in principle reach further back. In 2020, forensic toxicologists in Strasbourg reported the first identification of GW501516 in human hair, at 32 and 22 pg\/mg in two consecutive 2 cm segments from one male user, and noted that this was not expected for a molecule carrying a carboxylic acid group (Kintz et al., 2020).\u003c\/p\u003e\u003cp\u003eWhat no verified study gives is a detection window after capsules like these, whose strength is not even stated. For every compound in this bundle, the accurate position is: detectable, window not established. Anyone bound by an anti-doping code should treat any contact with these compounds as a risk of an adverse finding.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eWe can cite no published shelf-life study for ostarine, andarine or cardarine in capsule form, so we quote no shelf life. Work to the expiry date printed on each iMuscle container, and remember that a certificate describes a batch only on its test date.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the products apart.\u003c\/strong\u003e Leave each compound in its own labelled container. Capsules of different compounds can look alike, and once mixed or decanted they can no longer be matched to a lot number or a certificate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCool, dry and dark.\u003c\/strong\u003e A closed cupboard away from radiators, ovens and sunny windowsills. Close the lid after every opening; capsule shells take up moisture, so bathrooms and kitchens are poor places for them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRecord as you go.\u003c\/strong\u003e Note each lot number and the date its seal was broken. Label any sample taken for analysis with compound, lot and date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHandle as laboratory chemicals.\u003c\/strong\u003e Gloves for opened capsules or powder, no food or drink nearby, out of reach of children and pets, and disposal as chemical waste under local rules rather than in household bins or drains.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eOpening a container also ends the 30-day return option, which applies to unopened items only.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator, a non-steroidal compound that activates the androgen receptor; ostarine and andarine are SARMs, cardarine is not.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAryl-propionamide\u003c\/strong\u003e: the chemical family shared by ostarine and andarine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePPAR-delta\u003c\/strong\u003e: peroxisome proliferator-activated receptor delta, the nuclear receptor cardarine binds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eREV-ERB\u003c\/strong\u003e: a pair of circadian clock receptors targeted by SR9009, unrelated to PPAR-delta.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic modulator\u003c\/strong\u003e: the WADA category in section S4 that covers PPAR-delta agonists and AMPK activators.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCachexia\u003c\/strong\u003e: the muscle and weight loss that accompanies cancer and other chronic illness, the condition ostarine's phase III trials targeted.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStereocentre\u003c\/strong\u003e: an atom that allows two mirror-image forms of a molecule; ostarine and andarine each have one, cardarine has none.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC and LC-MS\u003c\/strong\u003e: liquid chromatography, alone or linked to mass spectrometry, used to identify a compound and measure its purity.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/ostarine\"\u003eOstarine (MK-2866) collection\u003c\/a\u003e and the \u003ca href=\"\/blogs\/news\/ostarine-mk-2866-research-guide\"\u003eostarine research guide\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/andarine\"\u003eAndarine (S-4) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/cardarine\"\u003eCardarine (GW-501516) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/sr9009\"\u003eSR9009 collection\u003c\/a\u003e and \u003ca href=\"\/collections\/sarms\"\u003eall SARMs\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-imuscle\"\u003eiMuscle brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eComparing listings by price per milligram\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eDalton JT, et al. The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial. J Cachexia Sarcopenia Muscle. 2011;2(3):153-161. PMID: 22031847.\u003c\/li\u003e\n\u003cli\u003eKearbey JD, et al. Selective Androgen Receptor Modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats. Pharm Res. 2007;24(2):328-35. PMID: 17063395.\u003c\/li\u003e\n\u003cli\u003eSprecher DL, et al. Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist. Arterioscler Thromb Vasc Biol. 2007;27(2):359-65. PMID: 17110604.\u003c\/li\u003e\n\u003cli\u003eVan Wagoner RM, et al. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004-2010. PMID: 29183075.\u003c\/li\u003e\n\u003cli\u003eKintz P, et al. Testing for GW501516 (cardarine) in human hair using LC\/MS-MS and confirmation by LC\/HRMS. Drug Test Anal. 2020;12(7):980-986. PMID: 32298044.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468980105442,"sku":null,"price":104.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/Combo8.jpg?v=1789931413"},{"product_id":"imuscle-testolon-yk11-ibutamoren","title":"iMuscle Testolone + YK-11 + Ibutamoren stack","description":"\u003cp\u003e\u003cstrong\u003eiMuscle Testolone + YK-11 + Ibutamoren stack\u003c\/strong\u003e is a 60-capsule combined listing from iMuscle, labelled as containing three research compounds: YK-11, Testolone (RAD-140) and Ibutamoren (MK-677). The manufacturer does not state the amount of each compound per capsule on the label. It is supplied through the \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e range for laboratory research only, is not for human consumption, and is sold to adults aged 18 and over. Each compound is covered in turn below.\u003c\/p\u003e\n\u003ch2\u003eThis listing\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eManufacturer: iMuscle\u003c\/li\u003e\n\u003cli\u003eCompounds named on the label: YK-11, Testolone (RAD-140) and Ibutamoren (MK-677)\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStrength: not stated by the manufacturer for any of the three compounds, so no per-capsule or per-pack figure is given\u003c\/li\u003e\n\u003cli\u003eBatch certificate of analysis: shown where iMuscle supplies one for the batch we hold\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over, for laboratory research only\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eiMuscle also sells each compound on its own with a stated strength: \u003ca href=\"\/products\/imuscle-yk-11-60-10mg\"\u003eiMuscle YK-11\u003c\/a\u003e, \u003ca href=\"\/products\/imuscle-testolon-rad-140-60-10mg\"\u003eiMuscle Testolone RAD-140\u003c\/a\u003e and \u003ca href=\"\/products\/imuscle-ibutamoren-mk-677-60-10mg\"\u003eiMuscle Ibutamoren MK-677\u003c\/a\u003e are each labelled 10 mg per capsule, 60 capsules.\u003c\/p\u003e\n\u003ch2\u003eThe three compounds in this pack\u003c\/h2\u003e\n\u003ch3\u003eYK-11\u003c\/h3\u003e\n\u003cp\u003eYK-11 is a synthetic steroidal compound, a 19-nortestosterone derivative carrying a methoxyethylidene group, that is marketed as a SARM. It was first described by Kanno and colleagues at Toho University in Japan (PubChem CID 119058028, CAS 1370003-76-1, C25H34O6).\u003c\/p\u003e\n\u003cp\u003eIn a 2011 cell-culture study using a reporter-gene assay, YK-11 acted as a partial agonist of the androgen receptor and activated it without the receptor's N\/C-terminal interaction that dihydrotestosterone induces (Kanno 2011). A 2013 study in mouse C2C12 myoblast cells reported that YK-11 increased follistatin expression and promoted myogenic differentiation through the androgen receptor, the origin of the myostatin-inhibitor description (Kanno 2013). Those are the founding primary studies; there are no human trials or toxicology data, and later work has been limited to a few rodent studies and doping-control metabolism research. It has never been approved as a medicine.\u003c\/p\u003e\n\u003ch3\u003eRAD-140 (Testolone)\u003c\/h3\u003e\n\u003cp\u003eRAD-140, also listed as testolone and vosilasarm, is a non-steroidal selective androgen receptor modulator designed by Radius Health (PubChem CID 44200882, CAS 1182367-47-0, C20H16ClN5O2). Its human data come from a single clinical trial. A first-in-human phase 1 study enrolled 22 postmenopausal women with oestrogen receptor-positive, HER2-negative metastatic breast cancer and gave RAD-140 by mouth (LoRusso 2022). The most frequent adverse events were raised AST in 59.1 per cent of participants, raised ALT in 45.5 per cent and raised bilirubin in 27.3 per cent, and 16 of the 22 had a grade 3 or 4 adverse event. The measured half-life was 44.7 hours. The trial assessed tolerability and tumour response, not muscle or strength, and RAD-140 has not been approved as a medicine anywhere.\u003c\/p\u003e\n\u003ch3\u003eMK-677 (Ibutamoren)\u003c\/h3\u003e\n\u003cp\u003eMK-677, or ibutamoren, is a non-peptide growth hormone secretagogue developed by Merck under the code L-163,191 (PubChem CID 178024, CAS 159634-47-6, C27H36N4O5S). It mimics ghrelin at the GHS-R1a receptor, prompting the pituitary to release growth hormone, and it raises IGF-1. Randomised trials in older adults and in obese men recorded higher growth hormone and IGF-1 together with poorer glucose handling, and in the older adults increased appetite and mild oedema (Nass 2008; Svensson 1998); those trials are summarised in \u003ca href=\"\/blogs\/news\/mk-677-ibutamoren-what-the-research-says\"\u003eMK-677 (ibutamoren): what the research says\u003c\/a\u003e. It was never approved as a medicine.\u003c\/p\u003e\n\u003cp\u003eEach compound was studied on its own. No published study has examined YK-11, RAD-140 and MK-677 together, in cells, animals or people. We do not advise on combining compounds; the listing is described as the manufacturer presents it. Nothing above is a claim about this product.\u003c\/p\u003e\n\u003ch2\u003eYK-11, RAD-140 and MK-677 in the UK: buying, legal status and what to check\u003c\/h2\u003e\n\u003cp\u003eNone of the three compounds is a licensed medicine in the UK. None holds an MHRA marketing authorisation, none is an authorised food supplement, and none may lawfully be sold for human consumption. Free Muscle supplies this pack to adults aged 18 and over for laboratory research only.\u003c\/p\u003e\n\u003cp\u003eThe three do not sit in identical positions. YK-11 is a steroid, and because anabolic steroids are Class C controlled drugs in the UK its status is less clear-cut than that of RAD-140, a non-steroidal SARM with no steroid backbone. MK-677 acts on the growth hormone axis; its UK position is set out on our \u003ca href=\"\/pages\/mk-677-legal-status-uk\"\u003eMK-677 legal status page\u003c\/a\u003e. All three are prohibited in sport. Buyers are responsible for the rules that apply to them, and our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e covers the wider legal picture.\u003c\/p\u003e\n\u003ch3\u003eWhat to check before buying a multi-compound pack\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eEvery compound named precisely, with a separate stated amount per capsule for each. A list of names alone does not say how much of anything is present.\u003c\/li\u003e\n\u003cli\u003eA printed lot number that ties the pack to a named laboratory's certificate.\u003c\/li\u003e\n\u003cli\u003eA certificate that identifies and quantifies each compound, not only the one in the product title.\u003c\/li\u003e\n\u003cli\u003eA named UK company, an 18+ restriction, plain packaging and tracked delivery.\u003c\/li\u003e\n\u003cli\u003eNo instructions for human use, no stacking advice and no promises of outcomes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHow this listing measures up\u003c\/h3\u003e\n\u003cp\u003eiMuscle does not state per-capsule amounts, so this listing fails the first check, and we do not fill the gap with an estimate. A certificate is shown only where iMuscle supplies one for the batch we hold. Orders ship from FreeMuscle LTD in Scunthorpe with free tracked UK delivery in plain packaging, orders placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3 to 7 working days, and unopened items can be returned within 30 days (\u003ca href=\"\/pages\/shipping\"\u003edelivery\u003c\/a\u003e, \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e). Our \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e explains each test.\u003c\/p\u003e\n\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\n\u003cp\u003eYK-11, RAD-140 and MK-677 are each sold separately as capsules, liquids and powder. No study has compared these forms for any of the three, so the points here concern what can be measured and kept stable, not effect. This pack is a single capsule said to hold all three.\u003c\/p\u003e\n\u003cp\u003ePutting three compounds in one fill changes the measurement problem. In a blend, the amount of each compound depends on how evenly the powders were mixed before filling, and a minor component that is poorly mixed can vary from capsule to capsule even when the total fill weight is consistent. Only a content assay of finished capsules, reporting each compound separately, shows the actual ratio.\u003c\/p\u003e\n\u003cp\u003eThe chemistry points the same way. All three are small molecules rather than peptides, so the digestion argument made about peptides taken by mouth, discussed in \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides actually work?\u003c\/a\u003e, does not apply to them. YK-11 carries an orthoester-derived group that its main metabolism study called arguably labile (Piper 2018), which makes a water-free fill easier to keep stable than a solution. MK-677 is often supplied as its mesylate salt, which weighs more than the free base, so a label amount should say which form it refers to. None of this is a claim about what a capsule does.\u003c\/p\u003e\n\u003ch2\u003eYK-11 compared with RAD-140 and MK-677, and where RAD-150 fits\u003c\/h2\u003e\n\u003cp\u003eA common question is how the three compounds differ, and how RAD-140 relates to RAD-150. The table uses only points that published sources support.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint\u003c\/th\u003e\n\u003cth\u003eYK-11\u003c\/th\u003e\n\u003cth\u003eRAD-140\u003c\/th\u003e\n\u003cth\u003eMK-677\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eChemical family\u003c\/td\u003e\n\u003ctd\u003eSteroidal, 19-nor skeleton\u003c\/td\u003e\n\u003ctd\u003eNon-steroidal SARM\u003c\/td\u003e\n\u003ctd\u003eNon-peptide ghrelin mimetic\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMain target\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor, partial agonist in cell assays\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor\u003c\/td\u003e\n\u003ctd\u003eGhrelin receptor (GHS-R1a)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and molecular weight\u003c\/td\u003e\n\u003ctd\u003eC25H34O6, 430.5\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2, 393.8\u003c\/td\u003e\n\u003ctd\u003eC27H36N4O5S, 528.7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDeveloped by\u003c\/td\u003e\n\u003ctd\u003eAcademic group, Toho University\u003c\/td\u003e\n\u003ctd\u003eRadius Health\u003c\/td\u003e\n\u003ctd\u003eMerck, as L-163,191\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublished human data\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003ctd\u003eOne phase 1 trial, 22 women with metastatic breast cancer\u003c\/td\u003e\n\u003ctd\u003eRandomised trials in older adults and obese men\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAdverse findings in people\u003c\/td\u003e\n\u003ctd\u003eNot studied\u003c\/td\u003e\n\u003ctd\u003eRaised liver enzymes and bilirubin\u003c\/td\u003e\n\u003ctd\u003ePoorer glucose handling, appetite, oedema\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA section\u003c\/td\u003e\n\u003ctd\u003eS1, anabolic agents\u003c\/td\u003e\n\u003ctd\u003eS1, anabolic agents\u003c\/td\u003e\n\u003ctd\u003eS2, growth hormone secretagogues\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eTwo of the three share a target. YK-11 and RAD-140 both act at the androgen receptor, though they come from unrelated chemical families, while MK-677 works on a separate system, the growth hormone and IGF-1 axis. On human evidence, MK-677 has the most trial data, RAD-140 a single oncology study, and YK-11 none. Nothing here ranks one above another for any purpose.\u003c\/p\u003e\n\u003cp\u003eRAD-150, also sold as TLB-150, is not in this pack. PubChem records it as the benzoate ester of RAD-140; it appears in a Radius Health patent but has no peer-reviewed study, so claims that it acts for longer are inference. It is stocked separately on the \u003ca href=\"\/collections\/rad-150\"\u003eRAD-150 collection page\u003c\/a\u003e, and \u003ca href=\"\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150 (TLB-150)\u003c\/a\u003e sets out the chemistry. For MK-677 the most searched comparison is with ipamorelin, a peptide acting at the same ghrelin receptor; see the \u003ca href=\"\/collections\/ipamorelin\"\u003eipamorelin collection\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/mk-677-vs-ipamorelin-vs-hgh\"\u003eMK-677 vs ipamorelin vs somatropin\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\n\u003cp\u003eiMuscle is a third-party brand in the Muscle Market range, so any certificate for this pack is the manufacturer's, not ours. We show one only where iMuscle supplies it for the specific batch we hold, and a generic PDF with no batch number is not a batch certificate, so we do not present one as such. Janoshik Analytical testing of every batch applies to Free Muscle-brand products only, not to iMuscle. A three-compound certificate has more to prove; check these fields.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number\u003c\/strong\u003e: the same number as the one printed on your pack.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity of each compound\u003c\/strong\u003e: a method such as HPLC against reference standards or LC-MS, with a separate result for YK-11 (C25H34O6, 430.5), RAD-140 (C20H16ClN5O2, 393.8) and MK-677 (C27H36N4O5S, 528.7 as the free base). A certificate that confirms only one of them says nothing about the other two.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule for each compound\u003c\/strong\u003e: because iMuscle states no strengths, these figures would be the only statement of how much of each is present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity\u003c\/strong\u003e: in a blend a single percentage is ambiguous, because three main peaks are expected. Look for each compound reported separately, with any unidentified peaks listed on their own.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest date and laboratory\u003c\/strong\u003e: a named lab and date allow the result to be confirmed at source.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor this listing a missing field has a specific meaning. With no certificate for the batch in stock, nothing independent confirms which compounds are present or in what amounts. With identity results but no content figures, the certificate confirms presence, not quantity. Email us through the \u003ca href=\"\/pages\/contact\"\u003econtact page\u003c\/a\u003e with the product name and batch number and we will send what we hold, or say plainly that there is none. See \u003ca href=\"\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\n\u003cp\u003eEvery compound in this pack is prohibited at all times, in and out of competition, on the WADA Prohibited List, which UK Anti-Doping applies in the UK. YK-11 and RAD-140 fall under section S1, anabolic agents, where RAD-140 is named; MK-677 falls under section S2 as a growth hormone secretagogue. Under strict liability an athlete answers for any prohibited substance found in their sample, whatever a label says.\u003c\/p\u003e\n\u003cp\u003eFor YK-11 there is direct evidence. The Cologne anti-doping laboratory followed deuterium-labelled YK-11 through urine. The parent compound never appeared, but fourteen metabolites did. Free metabolites were gone by 24 hours, whereas forms bound to glucuronic acid or sulfate remained measurable past 48 hours, and two of them were built into the laboratory's screen for anabolic agents (Piper 2018). That is one study, not a detection window. RAD-140 and MK-677 are screened for by accredited laboratories as well; this page cites no study that sets a window for either, so the accurate answer for both is detectable, window not established. A blood half-life is no guide to detection, since laboratories also target metabolites.\u003c\/p\u003e\n\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\n\u003cp\u003eNo stability study has been published for YK-11, RAD-140 or MK-677 capsules, singly or combined, so no shelf life is given here beyond any date iMuscle prints on the pack. A blend is only as stable as its least stable component. The ester and orthoester-derived groups of YK-11 can be split by water, which makes moisture the main avoidable risk for the whole capsule.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStore the sealed container cool, dry and out of direct light.\u003c\/li\u003e\n\u003cli\u003eReplace the lid straight after opening and leave any desiccant sachet in place.\u003c\/li\u003e\n\u003cli\u003eKeep capsules in their own labelled pot; once moved or mixed, they lose their link to any certificate.\u003c\/li\u003e\n\u003cli\u003eNote the date received alongside the batch number.\u003c\/li\u003e\n\u003cli\u003eSet aside soft, sticky or discoloured capsules and contact us with the batch number.\u003c\/li\u003e\n\u003cli\u003eWear gloves, work away from food, drink, children and pets, and treat any surplus as chemical waste.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOnly unopened items can be returned within 30 days.\u003c\/p\u003e\n\u003ch2\u003eGlossary\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAndrogen receptor\u003c\/strong\u003e: the receptor inside cells that testosterone switches on; YK-11 and RAD-140 both bind it, from different chemical starting points.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator; RAD-140 is one, while YK-11 is a steroid sold under the same label.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth hormone secretagogue\u003c\/strong\u003e: MK-677's class, meaning any substance that triggers growth hormone release from the pituitary gland.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHS-R1a\u003c\/strong\u003e: the receptor for the hunger hormone ghrelin, which MK-677 mimics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIGF-1\u003c\/strong\u003e: insulin-like growth factor 1, the hormone the liver releases when growth hormone rises; MK-677 trials tracked it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAST and ALT\u003c\/strong\u003e: liver enzymes whose blood levels rise when liver cells are damaged; the most frequent adverse findings in the RAD-140 phase 1 trial.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhase 1 trial\u003c\/strong\u003e: first-in-human testing that asks how well a compound is tolerated and how the body handles it, not whether it works.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMesylate salt\u003c\/strong\u003e: a form of a compound paired with methanesulfonic acid that weighs more than the free base.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlend uniformity\u003c\/strong\u003e: how evenly several powders are mixed before capsule filling, which decides whether each capsule holds the same ratio of compounds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: the rule under which a prohibited substance in an athlete's sample counts against them whether or not they knew it was there.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRelated\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/yk-11\"\u003eAll brands of YK-11 we stock, compared\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/rad-140\"\u003eRAD-140 (Testolone) collection\u003c\/a\u003e and \u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e and \u003ca href=\"\/collections\/market-bundles\"\u003eMuscle Market bundles\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/yk-11-what-is-known\"\u003eYK-11: a steroidal compound sold as a SARM, what is actually known\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (Testolone): what the research says\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/lab-tests\"\u003eBatch testing and certificates of analysis\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is supplied for laboratory research use only. It has not been evaluated by the MHRA, EMA or FDA. It is not a medicine, not a food supplement and not for human consumption. Sold only to adults aged 18 and over. Nothing on this page is medical, dosing or usage advice, and descriptions of published studies are not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eKanno Y, et al. (17alpha,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11) is a partial agonist of the androgen receptor. Biol Pharm Bull. 2011;34(3):318-23. PMID: 21372378.\u003c\/li\u003e\n\u003cli\u003eKanno Y, et al. Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression. Biol Pharm Bull. 2013;36(9):1460-5. PMID: 23995658.\u003c\/li\u003e\n\u003cli\u003ePiper T, et al. Studies on the in vivo metabolism of the SARM YK11: Identification and characterization of metabolites potentially useful for doping controls. Drug Test Anal. 2018;10(11-12):1646-56. PMID: 30379415.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. PMID: 34565686.\u003c\/li\u003e\n\u003cli\u003eNass R, et al. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008;149(9):601-11. PMID: 18981485.\u003c\/li\u003e\n\u003cli\u003eSvensson J, et al. Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure. J Clin Endocrinol Metab. 1998;83(2):362-9. PMID: 9467542.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468980367586,"sku":null,"price":133.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/Combo6_720x_99821e6c-59bc-47ce-b643-d4c07517bcfa.jpg?v=1789931420"},{"product_id":"thoroughbred-labs-research-system-bpc157-amp-tb500-capsule-ndash-thoroughbred-labs","title":"Thoroughbred Labs Research System — BPC-157 \u0026 TB-500","description":"\u003cp\u003eThe Thoroughbred Labs Research System pairing BPC-157 and TB-500 groups two capsule-form research peptides in one listing. BPC-157 is a synthetic gastric pentadecapeptide and TB-500 is a synthetic fragment of thymosin beta-4. Thoroughbred Labs lists the pack as 60 capsules. The manufacturer does not state a peptide content per capsule on this listing, so none is quoted. Supplied to adults for laboratory research only and not for human consumption. It is sold through \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eA bundle is a listing convenience only: it lets two compounds from one manufacturer be ordered in a single purchase. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product. \"Research System\" is the manufacturer's product name, not a description of a method. The sections below take BPC-157 first and TB-500 second, and keep them apart throughout.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this research system\u003c\/h2\u003e\u003ch3\u003eBPC-157\u003c\/h3\u003e\u003cp\u003eBPC-157 is a synthetic fifteen-amino-acid peptide based on a sequence from a human gastric protein. Its sequence is GEPPPGKPADDAGLV. Almost all published work is rodent and cell research, largely from one Croatian group, covering animal models of gut, tendon, muscle and vascular injury. No controlled human trial has been published, and oral absorption of any peptide is unproven. WADA lists it under S0 (non-approved substances). Compare brands on the \u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eTB-500 (Thymosin Beta-4 fragment)\u003c\/h3\u003e\u003cp\u003eTB-500 is the trade name for a synthetic fragment of thymosin beta-4, a 43-amino-acid actin-binding peptide present in most human and animal cells. Reviews of thymosin beta-4 cover preclinical wound, corneal and cardiac repair models and early clinical trials of the full peptide. TB-500 itself has no published human data. WADA names thymosin beta-4 and its derivatives, including TB-500, under S2. Compare brands on the \u003ca href=\"\/collections\/tb-500\"\u003eTB-500 (Thymosin Beta-4 fragment) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eProperty\u003c\/th\u003e\n\u003cth\u003eBPC-157\u003c\/th\u003e\n\u003cth\u003eThymosin beta-4 and TB-500\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eChain length\u003c\/td\u003e\n\u003ctd\u003e15 residues\u003c\/td\u003e\n\u003ctd\u003eParent protein 43 residues; the fragment found in TB-500 is 7 residues, Ac-LKKTETQ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular formula (PubChem)\u003c\/td\u003e\n\u003ctd\u003eC62H98N16O22\u003c\/td\u003e\n\u003ctd\u003eC212H350N56O78S (parent protein)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e1419.5 g\/mol\u003c\/td\u003e\n\u003ctd\u003eAbout 4,963 g\/mol for the parent; under 1,000 g\/mol for the fragment\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e137525-51-0\u003c\/td\u003e\n\u003ctd\u003eNone held in our PubChem record\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e9941957\u003c\/td\u003e\n\u003ctd\u003e45382195 (parent)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch3\u003eWhat the published research reports\u003c\/h3\u003e\u003cp\u003eThe BPC-157 citation below is a 2016 review written by the Zagreb researchers who first described the peptide. It gathers their rodent work on the gut, brain and blood vessels; independent replication is its main gap. The thymosin beta-4 citation is a 2012 review by Goldstein and colleagues, covering actin binding, cell movement and the skin, eye and heart programmes then in progress. Both reviews concern the peptides in general, delivered by routes other than capsules, and neither is a claim about this product.\u003c\/p\u003e\u003cp\u003eTwo analytical papers, covered under detection below, describe what products sold under these names actually contained. Both peptides here are in capsule form. Our article \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides actually work?\u003c\/a\u003e sets out why oral bioavailability of peptides is an open question and what that means for how this format is studied. Longer reviews are in \u003ca href=\"\/blogs\/news\/bpc-157-what-research-shows\"\u003eBPC-157: what the research actually shows\u003c\/a\u003e and the \u003ca href=\"\/blogs\/news\/tb-500-thymosin-beta-4-research-guide\"\u003eTB-500 and thymosin beta-4 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: Thoroughbred Labs (third-party brand, Muscle Market)\u003c\/li\u003e\n\u003cli\u003eCompounds: BPC-157 and TB-500 (thymosin beta-4 fragment)\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eSplit between the two peptides: not broken down on the listing\u003c\/li\u003e\n\u003cli\u003ePeptide content per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eTotal per pack: cannot be calculated without a stated strength\u003c\/li\u003e\n\u003cli\u003eCOA: only where Thoroughbred Labs supplies one for the batch held\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThoroughbred Labs also sells each peptide on its own, as \u003ca href=\"\/products\/thoroughbred-labs-bpc157-peptide-capsule-ndash-thoroughbred-labs\"\u003eThoroughbred Labs BPC-157 capsules\u003c\/a\u003e and \u003ca href=\"\/products\/thoroughbred-labs-tb500-peptide-capsule-ndash-thoroughbred-labs\"\u003eThoroughbred Labs TB-500 capsules\u003c\/a\u003e. None of the three states a strength, so they cannot be compared on milligrams; \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e explains why that matters.\u003c\/p\u003e\u003ch2\u003eBPC-157 and TB-500 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"BPC157 TB500 UK\" and \"BPC 157 UK legal\" ask whether the peptides can be sold here, and how to tell a documented listing from an anonymous one.\u003c\/p\u003e\u003ch3\u003eWhere the law stands\u003c\/h3\u003e\u003cp\u003eNone of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement. Neither peptide appears in the controlled drugs legislation. Free Muscle supplies them to adults aged 18 and over for laboratory research only. They are not for human consumption. No medicine licensed in the UK contains either peptide. BPC-157 is listed by WADA under S0 and TB-500 under S2. The \u003ca href=\"\/blogs\/news\/tb-500-thymosin-beta-4-research-guide\"\u003eTB-500 research guide\u003c\/a\u003e sets out the regulatory background for that peptide in more detail.\u003c\/p\u003e\u003ch3\u003eQuestions to put to any seller of a two-peptide pack\u003c\/h3\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhich peptides, in which containers?\u003c\/strong\u003e The listing should name both compounds, not only a product nickname.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow much of each?\u003c\/strong\u003e A stated amount per capsule for each peptide, or a plain admission that the maker gives none.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhich batch?\u003c\/strong\u003e A lot number on every container, since analytical results belong to a batch.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTested by whom?\u003c\/strong\u003e A certificate for that batch from a named laboratory, with a result for each peptide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSold on what terms?\u003c\/strong\u003e Adults only, research use stated, and no directions for use or promised outcomes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDelivered how?\u003c\/strong\u003e Tracked delivery, discreet packaging and written returns terms from a traceable company.\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch3\u003eHow this Thoroughbred Labs pack answers them\u003c\/h3\u003e\u003cp\u003eFreeMuscle LTD is a UK company in Scunthorpe. The manufacturer and both compounds are named, sales are limited to adults, and this page gives no directions for use. Every order goes by free tracked UK delivery in plain packaging; orders placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3 to 7 working days, and unopened items can be returned within 30 days. Two answers depend on Thoroughbred Labs: the listing gives no strength for either peptide, and a batch certificate exists only where the manufacturer has supplied one for the lot we hold. The \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e expands on each question.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eBoth peptides are sold in three broad formats: capsules or tablets, freeze-dried powder in sealed vials, and occasionally ready-made solutions. The published research does not map neatly onto any of them. BPC-157 studies in rats mostly gave the peptide by injection, with some Zagreb experiments adding it to drinking water. Thymosin beta-4 work used intravenous infusion, eye drops, gels applied to skin and injection in animals. Nobody has published a measurement of either peptide in human blood after a capsule was swallowed, so the search \"BPC 157 capsules vs injection\" has no answer in human data. The routes used in each study are set out in \u003ca href=\"\/blogs\/news\/bpc-157-capsules-vs-injection-what-studies-used\"\u003eBPC-157 capsules vs injection: what the studies used\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eThe obstacle for a swallowed peptide is chemical. Stomach acid unfolds proteins and pepsin begins cutting them, then pancreatic enzymes and the peptidases lining the small intestine finish the job, and an intact peptide would still have to cross the gut wall. The Zagreb group reports that BPC-157 withstands human gastric juice in its own tests; nothing comparable has been reported for the TB-500 fragment, whose two adjacent lysine residues are typical cleavage points for trypsin.\u003c\/p\u003e\u003cp\u003eAs materials, dry powder in a sealed shell or vial generally keeps better than peptide in water, and a capsule's content depends on how evenly the peptide was blended with filler. None of this implies that any format produces an effect.\u003c\/p\u003e\u003ch2\u003eBPC-157 compared with TB-500\u003c\/h2\u003e\u003cp\u003e\"TB 500 vs BPC 157\" is the comparison most often searched for these two. They share a market category and very little else.\u003c\/p\u003e\u003ch3\u003eOrigin and structure\u003c\/h3\u003e\u003cp\u003eBPC-157 was derived from a protein isolated in gastric juice; its 15 residues are rich in proline and include three aspartate and glutamate residues, which make it acidic. TB-500 is built on residues 17 to 23 of thymosin beta-4, the stretch of the parent protein that binds actin, with an acetyl group capping its start. At under 1,000 g\/mol the fragment is smaller than BPC-157 at 1419.5 g\/mol.\u003c\/p\u003e\u003ch3\u003eEvidence base\u003c\/h3\u003e\u003cp\u003eThe two literatures grew in different ways. BPC-157 research is concentrated in one university network and is almost entirely rodent and cell work, with no randomised human trial published. Thymosin beta-4 has been studied by many independent laboratories and taken into sponsored clinical programmes using the full protein, none of which has yet led to an approved medicine. No study has ever compared BPC-157 and TB-500 directly, so neither can be ranked above the other.\u003c\/p\u003e\u003ch3\u003eRegulation and sport\u003c\/h3\u003e\u003cp\u003eIn the UK both are unlicensed research compounds without MHRA, EMA or FDA approval. Their WADA sections differ: BPC-157 is in S0 because it has no approval for human therapeutic use, while TB-500 falls in S2 because the list names thymosin beta-4 and its derivatives. The practical result is identical, as both are prohibited at all times. Brands are compared on the \u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection\u003c\/a\u003e and \u003ca href=\"\/collections\/tb-500\"\u003eTB-500 collection\u003c\/a\u003e pages, and the wider peptide class is discussed in \u003ca href=\"\/blogs\/news\/sarms-vs-peptides-choosing-by-goal\"\u003eSARMs vs peptides\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eThoroughbred Labs is a third-party brand sold through Muscle Market. For third-party brands we display a certificate of analysis only where the manufacturer supplies one for the exact batch we hold; if none is shown, none has been supplied and we do not substitute a generic document. Free Muscle-brand products, by contrast, are assayed batch by batch at Janoshik Analytical, with the certificate sent on request by email, as for our own \u003ca href=\"\/products\/tb-500-thymosin-beta-4-peptide-free-muscle\"\u003eFree Muscle TB-500\u003c\/a\u003e. That testing does not extend to Thoroughbred Labs. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e explains what a certificate shows.\u003c\/p\u003e\u003cp\u003eA pack with two peptides needs evidence for two identities, so a report that names only one compound covers only half of it. Points to look for:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity for each peptide.\u003c\/strong\u003e HPLC matches a peak to the retention time of a reference standard; LC-MS adds a measured mass. A BPC-157 result should sit at about 1419.5 g\/mol. For TB-500 the mass shows which molecule is present: under 1,000 g\/mol fits the acetylated fragment, around 4,963 g\/mol the full protein.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity percentage.\u003c\/strong\u003e How much of the detected signal belongs to the named peptide rather than synthesis by-products. It says nothing about quantity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent.\u003c\/strong\u003e The only field that could supply the strength this listing omits, ideally per capsule and stating whether net peptide or total powder was measured.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number and test date.\u003c\/strong\u003e The lot on the report must match the lot on the container, and the date shows how current the result is.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eFor this brand a gap has a direct consequence: no mass leaves the TB-500 identity open, no content line leaves both strengths unknown, and no batch number means the report cannot be tied to the capsules in hand. \u003ca href=\"\/pages\/contact\"\u003eContact us\u003c\/a\u003e with the batch number and we will say what documentation exists for current stock. \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003eHow to read a certificate of analysis\u003c\/a\u003e works through a full example.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eUnder the World Anti-Doping Code, applied in the UK by UK Anti-Doping, both peptides in this pack are prohibited. BPC-157 sits in S0 and TB-500 in S2, and both classes are banned in and out of competition. Strict liability applies: an athlete answers for whatever a sample contains.\u003c\/p\u003e\u003cp\u003eLaboratories have published detection methods for each peptide. For TB-500, the Ghent doping control laboratory identified Ac-LKKTETQ by high-resolution mass spectrometry, synthesised it as a reference material and suggested a plasma and urine detection route. For BPC-157, the Salt Lake City laboratory validated a urine method with a limit of detection of 0.1 ng\/mL, showed the peptide remained stable in urine for at least four days, and added a stable metabolite as a second marker to improve specificity. Neither study followed people after exposure, so no human detection window has been established for either peptide. The accurate position is: detectable, window not established.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eNo stability study has been published for BPC-157 or TB-500 in capsule form, so the manufacturer's expiry or best-before date, where printed, is the limit to work to. Moisture drives hydrolysis and softens capsule shells, heat speeds degradation, and air and light encourage oxidation. Thymosin beta-4 carries a methionine residue that oxidises readily; the TB-500 fragment does not include it, but its lysine-rich sequence attracts water.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eKeep the container firmly closed in a cool, dark, dry cupboard, away from radiators, steam and sunlight.\u003c\/li\u003e\n\u003cli\u003eLeave any desiccant in place. A refrigerated container should reach room temperature before it is opened, so condensation does not form on the contents.\u003c\/li\u003e\n\u003cli\u003eKeep capsules in their original container. The printed lot number is the only link to a certificate, and only unopened packs qualify for the 30-day return.\u003c\/li\u003e\n\u003cli\u003eWork with opened capsules as you would any laboratory reagent: wear gloves, keep them apart from food and drink and out of reach of children and pets, and send unwanted material for chemical waste disposal.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePentadecapeptide\u003c\/strong\u003e: a peptide of fifteen amino acids, the class to which BPC-157 belongs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThymosin beta-4\u003c\/strong\u003e: a 43-amino-acid protein that binds actin inside cells; the parent of TB-500.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSolid-phase peptide synthesis\u003c\/strong\u003e: the standard laboratory method of building a peptide one residue at a time on a resin support.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBioavailability\u003c\/strong\u003e: the fraction of a substance that reaches the circulation intact after it is given by a particular route.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetention time\u003c\/strong\u003e: the point at which a compound emerges from an HPLC column; matching it to a reference standard is the first identity check.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLC-MS\u003c\/strong\u003e: liquid chromatography combined with mass spectrometry, which separates compounds and then measures their mass.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLimit of detection\u003c\/strong\u003e: the smallest amount a test can tell apart from nothing, 0.1 ng\/mL for the BPC-157 urine method cited below.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eS0 and S2\u003c\/strong\u003e: the two WADA list sections relevant here, the first catching substances with no approval for human therapy, the second peptide hormones, growth factors and their relatives.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/tb-500\"\u003eTB-500 (Thymosin Beta-4) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-thoroughbred-labs\"\u003eThoroughbred Labs brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/peptides\"\u003ePeptides collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eSikiric P, et al. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Curr Neuropharmacol. 2016;14(8):857-865. PMID: 27138887.\u003c\/li\u003e\n\u003cli\u003eGoldstein AL, et al. Thymosin beta4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther. 2012;12(1):37-51. PMID: 22074294.\u003c\/li\u003e\n\u003cli\u003eEsposito S, et al. Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential. Drug Test Anal. 2012;4(9):733-8. PMID: 22962027.\u003c\/li\u003e\n\u003cli\u003eCox HD, et al. Detection and in vitro metabolism of the confiscated peptides BPC 157 and MGF R23H. Drug Test Anal. 2017;9(10):1490-1498. PMID: 28035768.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Thoroughbred Labs","offers":[{"title":"Default Title","offer_id":48468980793570,"sku":null,"price":74.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/wolverine_stack_76843378-86b0-45d7-94f0-701509583091.png?v=1789931431"},{"product_id":"thoroughbred-labs-research-system-slu-pp-332-amp-5-amino-1mq-ndash-thoroughbred-labs","title":"Thoroughbred Labs Research System — SLU-PP-332 \u0026 5-Amino-1MQ","description":"\u003cp\u003eThe \u003cstrong\u003eThoroughbred Labs Research System\u003c\/strong\u003e pairing SLU-PP-332 and 5-Amino-1MQ places two of the newest and least characterised compounds in this market in one listing. SLU-PP-332 is an oestrogen-related receptor agonist and 5-Amino-1MQ is an NNMT inhibitor. Thoroughbred Labs lists the pack as 60 capsules and does not state a strength per capsule, so we do not quote one. It is part of the \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e range, supplied to adults aged 18 and over for laboratory research only, and not for human consumption.\u003c\/p\u003e\n\u003cp\u003eA bundle is a listing convenience only: it lets separately packaged products from one manufacturer be ordered in a single purchase. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product. Each compound is described separately below.\u003c\/p\u003e\n\u003ch2\u003eAbout the compounds in this research system\u003c\/h2\u003e\n\u003ch3\u003eSLU-PP-332\u003c\/h3\u003e\n\u003cp\u003eSLU-PP-332 is a synthetic pan-agonist of the oestrogen-related receptors ERR alpha, beta and gamma. In a 2023 study in mice it induced a gene-expression pattern resembling acute aerobic exercise and increased running endurance (Billon et al., 2023). Every published study is preclinical and most come from the discovering group, led by Thomas Burris and John Walker. There is no human data, no toxicology package and no approval anywhere. Compare brands on the \u003ca href=\"\/collections\/slu-pp-332\"\u003eSLU-PP-332 collection page\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003e5-Amino-1MQ\u003c\/h3\u003e\n\u003cp\u003e5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme more active in fat tissue during obesity. In a 2018 study, diet-induced obese mice treated with the compound had lower body weight and white fat mass than untreated obese controls (Neelakantan et al., 2018). That is the extent of the in vivo literature on which this page relies: no human studies, no safety profile, no approval anywhere. Compare brands on the \u003ca href=\"\/collections\/5-amino-1mq\"\u003e5-Amino-1MQ collection page\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eChemical identifiers side by side\u003c\/h3\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIdentifier\u003c\/th\u003e\n\u003cth\u003eSLU-PP-332\u003c\/th\u003e\n\u003cth\u003e5-Amino-1MQ\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e5338394\u003c\/td\u003e\n\u003ctd\u003e950107\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e303760-60-3\u003c\/td\u003e\n\u003ctd\u003e685079-15-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula\u003c\/td\u003e\n\u003ctd\u003eC18H14N2O2 (neutral molecule)\u003c\/td\u003e\n\u003ctd\u003eC10H11N2+ (cation, sold as a salt)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e290.3\u003c\/td\u003e\n\u003ctd\u003e159.21 (ion only)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSystematic name\u003c\/td\u003e\n\u003ctd\u003e4-hydroxy-N-[(E)-naphthalen-2-ylmethylideneamino]benzamide\u003c\/td\u003e\n\u003ctd\u003e1-methylquinolin-1-ium-5-amine\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eOne is an uncharged hydrazone, the other a permanently charged ion, so they are analysed and stored with different concerns in mind. Neither is a peptide, a steroid or a SARM.\u003c\/p\u003e\n\u003ch2\u003eThis listing\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: Thoroughbred Labs (third-party brand, Muscle Market)\u003c\/li\u003e\n\u003cli\u003eCompounds: SLU-PP-332 and 5-Amino-1MQ\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eCOA: only where Thoroughbred Labs supplies one for the batch held\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe manufacturer's listing gives a single pack figure of 60 capsules and no strength for either compound, so the quantity of each compound in the order cannot be calculated from the listing. The labels on the packs, and any certificate supplied for the batch, are the only documents that can settle it. Both compounds are also sold on their own by the same brand, as \u003ca href=\"\/products\/thoroughbred-labs-slu\"\u003eThoroughbred Labs SLU-PP-332\u003c\/a\u003e and \u003ca href=\"\/products\/thoroughbred-labs-5-amino-1mq\"\u003eThoroughbred Labs 5-Amino-1MQ\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eSLU-PP-332 and 5-Amino-1MQ in the UK: buying, legal status and what to check\u003c\/h2\u003e\n\u003cp\u003eSearches such as \"SLU PP 332 UK buy\" and \"5 amino 1mq UK\" ask whether a UK shop may sell these compounds and how to judge a listing. A two-compound pack doubles the checks, since each applies to each compound.\u003c\/p\u003e\n\u003ch3\u003eThe legal position\u003c\/h3\u003e\n\u003cp\u003eNone of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement. Neither is a controlled drug. No medicine containing either has been approved anywhere, so a listing that presents them as a slimming product, endurance aid or supplement describes something they cannot lawfully be. Free Muscle supplies them to adults aged 18 and over for laboratory research only. They are not for human consumption. Neither compound has been named individually on recent editions of the WADA list, but the list also prohibits any non-approved substance under S0, which covers both, and metabolic modulators are prohibited as a class. Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e has more background on how research compounds are regulated.\u003c\/p\u003e\n\u003ch3\u003eWhat a trustworthy listing for a two-compound pack shows\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBoth compounds named\u003c\/strong\u003e, with the manufacturer identified on the page and on each pack.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated strength for each compound\u003c\/strong\u003e, or an open statement that the manufacturer gives none. A figure for one compound says nothing about the other.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA batch number on each pack\u003c\/strong\u003e, since two products made separately rarely share a lot.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate per batch\u003c\/strong\u003e, or one certificate that reports both compounds and quotes both batch numbers.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo directions and no promised outcomes\u003c\/strong\u003e, with research-use and 18+ terms stated plainly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA reachable UK seller\u003c\/strong\u003e with published delivery and returns terms.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHow this listing measures up\u003c\/h3\u003e\n\u003cp\u003eThe manufacturer is named, and the absent strength is stated rather than estimated. Certificates depend on what Thoroughbred Labs has supplied for the batches in stock, and we say which applies. FreeMuscle LTD is a UK company based in Scunthorpe. Every UK order goes by free tracked delivery in plain packaging, orders placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3-7 working days, and unopened items may be returned within 30 days. Details are on the \u003ca href=\"\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages, and the \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e applies the same tests to any shop.\u003c\/p\u003e\n\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\n\u003cp\u003eBoth compounds are searched for as capsules, tablets and injectables, and the question behind those searches is whether the form matters. For each compound the published record answers only part of it.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSLU-PP-332.\u003c\/strong\u003e The published mouse work gave the compound by injection, so no published result describes a swallowed capsule. The same research group has since reported a successor, SLU-PP-915, which it describes as orally active in mice (Billon et al., 2026); that finding concerns a different molecule and cannot be read across to SLU-PP-332. How much of a capsule's content survives the stomach and is absorbed has not been measured in any species.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e5-Amino-1MQ.\u003c\/strong\u003e The 2018 mouse study also used injection. The compound carries a fixed positive charge, and charged molecules tend to cross the gut wall less readily than neutral ones, although that is a general rule rather than a measurement in people. No study has measured oral absorption in humans.\u003c\/p\u003e\n\u003cp\u003eNeither is a peptide, so the gut-enzyme argument in our article \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e does not apply to them.\u003c\/p\u003e\n\u003cp\u003eThe measurable differences between forms are practical. A capsule holds a weighed fill of powder blended with filler, so the amount per capsule depends on fill weight and how evenly the blend was mixed. A liquid is measured by volume and relies on the compound staying dissolved and intact, which matters for a hydrazone that water can slowly split. None of this is a claim about effect.\u003c\/p\u003e\n\u003ch2\u003eSLU-PP-332 and 5-Amino-1MQ compared with SR9009\u003c\/h2\u003e\n\u003cp\u003eThe metabolic research compound most often searched in the same breath as these two is \u003ca href=\"\/collections\/sr9009\"\u003eSR9009 (Stenabolic)\u003c\/a\u003e, and the comparison has a genuine thread: SR9009 and SLU-PP-332 came out of laboratories led by the same researcher, Thomas Burris, a decade apart. SR9009 was described in 2012 at the Scripps Research Institute as a synthetic agonist of REV-ERB alpha and beta, nuclear receptors that link the body clock to metabolism (Solt et al., 2012).\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint of comparison\u003c\/th\u003e\n\u003cth\u003eSLU-PP-332\u003c\/th\u003e\n\u003cth\u003e5-Amino-1MQ\u003c\/th\u003e\n\u003cth\u003eSR9009\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTarget\u003c\/td\u003e\n\u003ctd\u003eERR alpha, beta and gamma (activated)\u003c\/td\u003e\n\u003ctd\u003eNNMT enzyme (inhibited)\u003c\/td\u003e\n\u003ctd\u003eREV-ERB alpha and beta (activated)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFirst in vivo report\u003c\/td\u003e\n\u003ctd\u003e2023, mice\u003c\/td\u003e\n\u003ctd\u003e2018, mice\u003c\/td\u003e\n\u003ctd\u003e2012, mice\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman trials\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA position\u003c\/td\u003e\n\u003ctd\u003eNot named; S0\u003c\/td\u003e\n\u003ctd\u003eNot named; S0\u003c\/td\u003e\n\u003ctd\u003eNamed in S4, metabolic modulators\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK status\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism.\u003c\/strong\u003e Each acts at a different point. SLU-PP-332 switches on the ERR family, which governs how many mitochondria cells build. SR9009 switches on REV-ERB, which represses clock genes and reshapes their daily rhythm. 5-Amino-1MQ is not a receptor ligand at all: it blocks an enzyme that methylates nicotinamide. None acts at the androgen receptor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEvidence.\u003c\/strong\u003e The 2012 SR9009 paper reported altered circadian behaviour and clock-gene patterns in mice, and lower fat mass with improved blood lipids and glucose in diet-induced obese mice. SR9009 has since shown what a longer record can reveal. In 2019 an independent group bred mice lacking both REV-ERB proteins and found that SR9009 still reduced cell viability and changed metabolism and gene transcription in their liver cells and stem cells, so its effects cannot all be credited to REV-ERB (Dierickx et al., 2019). SLU-PP-332 and 5-Amino-1MQ have not yet been through that kind of outside scrutiny, so their records are thinner still.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRegulation.\u003c\/strong\u003e All three are unlicensed in the UK and sold only for research. In sport SR9009 is prohibited by name, while the other two are caught by the catch-all S0 section. We do not rank research compounds by effect. The \u003ca href=\"\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 research guide\u003c\/a\u003e covers it in depth, and the \u003ca href=\"\/products\/imuscle-stenabolic-sr-9009-60-10mg\"\u003eiMuscle Stenabolic SR-9009\u003c\/a\u003e listing is stocked.\u003c\/p\u003e\n\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\n\u003cp\u003eThoroughbred Labs is a third-party brand sold through Muscle Market. For third-party brands we display a certificate of analysis only where the manufacturer supplies one for the exact batch we hold; if none is shown, none has been supplied and we do not substitute a generic document. Free Muscle-brand products, by contrast, are assayed batch by batch at Janoshik Analytical, with the certificate sent on request by email. For a two-compound pack, check that the paperwork covers both, line by line:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhich compound it reports.\u003c\/strong\u003e A certificate naming only SLU-PP-332 says nothing about the 5-Amino-1MQ in the same order, and the reverse.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity by mass.\u003c\/strong\u003e HPLC matches a peak to a reference standard by retention time; LC-MS adds a measured mass. SLU-PP-332 should give an ion near m\/z 291 after gaining a proton. 5-Amino-1MQ is already charged and should appear near m\/z 159 as it is.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity percentage.\u003c\/strong\u003e The share of the chromatogram taken by the main peak. For SLU-PP-332, small extra peaks may be its hydrolysis products or its other geometric isomer. Purity describes the powder, not the amount per capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e With no strength on the label, this is the only line that states a quantity. For 5-Amino-1MQ, check whether the figure counts the whole salt or the ion alone, since the two give different numbers for the same capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number, laboratory and test date.\u003c\/strong\u003e The number must match the pack in front of you; the laboratory and date show who tested it and when.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eA missing field has a plain meaning: no identity line means nothing confirms the compound, no content line leaves the quantity unknown, and a mismatched batch number means the document describes other stock. \u003ca href=\"\/pages\/contact\"\u003eContact us\u003c\/a\u003e with both lot numbers and we will send what we hold or say there is nothing. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e and the guide on \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e give worked examples.\u003c\/p\u003e\n\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\n\u003cp\u003eFor anyone bound by an anti-doping code, both compounds in this system are prohibited at all times, in and out of competition. Neither has appeared by name on recent editions of the WADA Prohibited List, but section S0 covers any pharmacological substance with no current approval for human therapeutic use, and neither has ever been approved.\u003c\/p\u003e\n\u003cp\u003eAnti-doping laboratories have already published in vitro studies of SLU-PP-332 metabolism, identifying metabolites by mass spectrometry that screening could target; one, from the UCLA Olympic Analytical Laboratory, was written explicitly for doping-control purposes (Avliyakulov et al., 2026). We found no comparable anti-doping study for 5-Amino-1MQ. What is missing for both is any excretion study in people, so no detection window has been established for either. The accurate position is detectable in principle, window not established. Under strict liability an athlete is responsible for any prohibited substance found in a sample, whatever its source.\u003c\/p\u003e\n\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\n\u003cp\u003eThoroughbred Labs has not published stability data for these capsules and no independent stability study exists for either compound, so the expiry date on each pack is the only stated limit. Chemistry points to different risks for each. The hydrazone bond in SLU-PP-332 can be split by water, faster in acid, and its extended ring system absorbs ultraviolet light. 5-Amino-1MQ, as an organic salt with an aromatic amino group, is prone to taking up moisture and to slow oxidation and discolouration in air and light.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLeave each compound in the container it arrived in, reseal it straight after opening, and do not remove any drying sachet.\u003c\/li\u003e\n\u003cli\u003eChoose a shelf that stays cool, dry and dark with little temperature swing; bathrooms, kitchens and sunny sills are poor choices.\u003c\/li\u003e\n\u003cli\u003eKeep each pack with its own label, because each batch number links to its own certificate.\u003c\/li\u003e\n\u003cli\u003eSet aside capsules that have clumped or changed colour.\u003c\/li\u003e\n\u003cli\u003eStore where children and pets cannot reach, apart from anything edible, and treat unwanted capsules as chemical waste under normal laboratory rules.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eGlossary\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOestrogen-related receptors (ERRs)\u003c\/strong\u003e: three orphan nuclear receptors, named for their resemblance to the oestrogen receptor, that steer mitochondrial and fuel-use genes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePan-agonist\u003c\/strong\u003e: an activator that works across a whole receptor family rather than one member; SLU-PP-332 is described this way because it reaches all three ERRs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNNMT\u003c\/strong\u003e: nicotinamide N-methyltransferase, the enzyme 5-Amino-1MQ inhibits.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eREV-ERB\u003c\/strong\u003e: alpha and beta forms of a clock-controlled nuclear receptor that represses target genes; SR9009 was built to activate them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHydrazone\u003c\/strong\u003e: a carbon-nitrogen double bond joined to a second nitrogen, the link that water can split in SLU-PP-332.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuinolinium ion\u003c\/strong\u003e: the positively charged, methylated quinoline skeleton of 5-Amino-1MQ, which is why it is always sold paired with a counter-ion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003em\/z\u003c\/strong\u003e: mass-to-charge ratio, the value a mass spectrometer reports for an ion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eS0 (non-approved substances)\u003c\/strong\u003e: the opening section of the WADA list, catching any drug not approved for human treatment even if it is never named.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: in anti-doping, the athlete answers for what is in the sample; how it got there does not change the finding.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRelated\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/slu-pp-332\"\u003eSLU-PP-332 collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/5-amino-1mq\"\u003e5-Amino-1MQ collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/sr9009\"\u003eSR9009 collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-thoroughbred-labs\"\u003eThoroughbred Labs brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/weight-loss\"\u003eMetabolic support collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/slu-pp-332-and-5-amino-1mq-research-guide\"\u003eSLU-PP-332 and 5-Amino-1MQ research guide\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eBillon C, et al. Synthetic ERRalpha\/beta\/gamma Agonist Induces an ERRalpha-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chem Biol. 2023;18(4):756-771. PMID: 36988910.\u003c\/li\u003e\n\u003cli\u003eNeelakantan H, et al. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice. Biochem Pharmacol. 2018;147:141-152. PMID: 29155147.\u003c\/li\u003e\n\u003cli\u003eSolt LA, et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature. 2012;485(7396):62-68. PMID: 22460951.\u003c\/li\u003e\n\u003cli\u003eDierickx P, et al. SR9009 has REV-ERB-independent effects on cell proliferation and metabolism. Proc Natl Acad Sci U S A. 2019;116(25):12147-12152. PMID: 31127047.\u003c\/li\u003e\n\u003cli\u003eAvliyakulov NK, et al. Analysis and Identification of In Vitro Metabolites of Exercise Mimetic SLU-PP-332 ERRalpha\/beta\/gamma Agonist for Doping-Control Purposes. Drug Test Anal. 2026;18(3):439-450. PMID: 41688415.\u003c\/li\u003e\n\u003cli\u003eBillon C, et al. An orally active estrogen receptor-related receptor agonist, SLU-PP-915, enhances aerobic exercise capacity. J Pharmacol Exp Ther. 2026;393(1):103787. PMID: 41421047.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Thoroughbred Labs","offers":[{"title":"Default Title","offer_id":48468980826338,"sku":null,"price":148.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/stack5_86866926-ecf4-4047-b242-37d52d6cd809.png?v=1789931432"},{"product_id":"yakka-strength-yakka-strength-mk677-bpc157-capsule-bundle","title":"Yakka Strength MK-677 \u0026 BPC-157 Capsule Bundle","description":"\u003cp\u003eThe Yakka Strength MK-677 and BPC-157 capsule bundle pairs ibutamoren (MK-677), an orally active growth hormone secretagogue, with BPC-157, a synthetic gastric pentadecapeptide, from the same manufacturer in one listing within our \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e range. Yakka Strength lists the pack as 60 capsules and does not state a content per capsule, so we quote none. Supplied to adults for laboratory research only and not for human consumption.\u003c\/p\u003e\u003cp\u003eA bundle is a listing convenience only: it lets separately packaged products from one manufacturer be ordered in a single purchase. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eMK-677 (Ibutamoren)\u003c\/h3\u003e\u003cp\u003eIbutamoren (MK-677, L-163,191, nutrobal) is not a SARM but an orally active ghrelin receptor (GHS-R1a) agonist, a growth hormone secretagogue. In a placebo-controlled trial in 65 healthy adults aged 60 to 81, growth hormone and IGF-1 rose over one year; fat-free mass rose by about 1.1 kg while it fell by about 0.5 kg on placebo, with no change in strength or function. Reported adverse findings included increased appetite, mild leg oedema, higher fasting glucose, reduced insulin sensitivity and raised cortisol. Never approved. WADA class S2. Compare brands on the \u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eBPC-157\u003c\/h3\u003e\u003cp\u003eBPC-157 is a synthetic fifteen-amino-acid peptide based on a sequence from a human gastric protein. Almost all published work is rodent and cell research, largely from one Croatian group, covering animal models of gut, tendon, muscle and vascular injury. No controlled human trial has been published, and oral absorption of any peptide is unproven. WADA lists it under S0 (non-approved substances). Compare brands on the \u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eThe first formal pharmacokinetic study of BPC-157, published in 2022 by a group in Xi'an, gave the peptide to rats and beagle dogs by intravenous and intramuscular injection. The unchanged peptide had an elimination half-life under 30 minutes, bioavailability after intramuscular injection was roughly 14-19% in rats and 45-51% in dogs, and radiolabelled material was quickly broken into small fragments and single amino acids, excreted mainly in urine and bile. The study included no oral arm, so it says nothing directly about capsules; it does show how short-lived the intact molecule was even when injected.\u003c\/p\u003e\u003ch3\u003eChemical identifiers\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eProperty\u003c\/th\u003e\n\u003cth\u003eIbutamoren\u003c\/th\u003e\n\u003cth\u003eBPC-157\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eChemical class\u003c\/td\u003e\n\u003ctd\u003eSpiroindoline small molecule\u003c\/td\u003e\n\u003ctd\u003eLinear peptide of 15 residues\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePeptide bonds\u003c\/td\u003e\n\u003ctd\u003eNone in the backbone\u003c\/td\u003e\n\u003ctd\u003eFourteen\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular formula\u003c\/td\u003e\n\u003ctd\u003eC27H36N4O5S\u003c\/td\u003e\n\u003ctd\u003eC62H98N16O22\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e528.7 g\/mol\u003c\/td\u003e\n\u003ctd\u003e1419.5 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e159634-47-6\u003c\/td\u003e\n\u003ctd\u003e137525-51-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e178024\u003c\/td\u003e\n\u003ctd\u003e9941957\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eFigures are from PubChem; an identity result on a certificate should match them. BPC-157 here is in capsule form. Our article \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides actually work?\u003c\/a\u003e covers why oral absorption of peptides remains unproven.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: Yakka Strength (third-party brand, Muscle Market)\u003c\/li\u003e\n\u003cli\u003eCompounds: ibutamoren (MK-677) and BPC-157\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eContent per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eCOA: only where Yakka Strength supplies one for the batch held\u003c\/li\u003e\n\u003cli\u003eBuyers: adults aged 18 and over, for laboratory research only\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eBecause no milligram figure is given for either compound, the total content of the pack cannot be worked out, and the bundle cannot be compared with single packs on cost per milligram. Our guide to \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e explains the method for listings that do state strength. Yakka Strength also sells \u003ca href=\"\/products\/yakka-strength-yakka-strength-mk677\"\u003eMK-677\u003c\/a\u003e and \u003ca href=\"\/products\/yakka-strength-yakka-strength-bpc157-peptide-capsules\"\u003eBPC-157 capsules\u003c\/a\u003e as separate listings.\u003c\/p\u003e\u003ch2\u003eMK-677 and BPC-157 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"MK677 UK buy\", \"MK 677 UK legal\" and \"BPC 157 capsules UK\" ask whether a purchase is lawful and how to tell a documented seller from an undocumented one.\u003c\/p\u003e\u003ch3\u003eLegal status, compound by compound\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eMK-677.\u003c\/strong\u003e Ibutamoren has never been authorised as a medicine in the UK or anywhere else, and it is not listed under the Misuse of Drugs Act. Our \u003ca href=\"\/pages\/mk-677-legal-status-uk\"\u003eMK-677 legal status page\u003c\/a\u003e sets out the position in more detail.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBPC-157.\u003c\/strong\u003e The peptide has no marketing authorisation in any country and is not a controlled drug in the UK. It is not an authorised food supplement, so capsule packaging does not make it a food product.\u003c\/p\u003e\u003cp\u003eNone of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement. Free Muscle supplies them to adults aged 18 and over for laboratory research only. They are not for human consumption. MK-677 falls under WADA class S2 and BPC-157 under S0. Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e has more background.\u003c\/p\u003e\u003ch3\u003eSigns of a well-documented listing\u003c\/h3\u003e\u003cp\u003eWhatever the compound, the same questions separate a seller who can account for its stock from one who cannot:\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eIs the manufacturer named, and does each container carry a lot or batch number?\u003c\/li\u003e\n\u003cli\u003eIs there a certificate of analysis for that lot, from a named laboratory, rather than a generic document reused across batches?\u003c\/li\u003e\n\u003cli\u003eIs the strength stated, or does the listing say plainly that it is not?\u003c\/li\u003e\n\u003cli\u003eIs sale restricted to adults, with no dosing directions or promised results?\u003c\/li\u003e\n\u003cli\u003eIs the seller a traceable UK business with published delivery and returns terms?\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch3\u003eHow this listing measures up\u003c\/h3\u003e\u003cp\u003eFreeMuscle LTD is a UK company based in Scunthorpe. Every order goes by free tracked UK delivery in plain packaging, orders placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3-7 working days, and unopened items may be returned within 30 days (see \u003ca href=\"\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eour guarantee\u003c\/a\u003e). The manufacturer is named. Two points depend on Yakka Strength: the label states no content per capsule for either compound, so question three is answered by that disclosure rather than a figure, and a certificate is displayed only where the manufacturer supplies one for the batch we hold. The \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e goes through each check in more depth.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eBoth compounds are sold as capsules, tablets and liquids, and BPC-157 also as freeze-dried powder for reconstitution. The molecule is identical in each; what differs is the route research used and how well the material keeps.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIbutamoren\u003c\/strong\u003e was built as a non-peptide precisely so that it would survive being swallowed. The randomised human trials, including the one-year study summarised above, gave it by mouth, so a capsule matches the route that was studied.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBPC-157\u003c\/strong\u003e is different. Most rodent studies gave it by injection into the abdominal cavity, with a smaller number adding it to drinking water, and the 2022 pharmacokinetic study used only intravenous and intramuscular routes. No study has measured blood levels in people after an oral dose. A fifteen-residue chain is exactly the kind of substrate that stomach and intestinal enzymes are there to break down. The question of routes is covered at length in \u003ca href=\"\/blogs\/news\/bpc-157-capsules-vs-injection-what-studies-used\"\u003eBPC-157 capsules vs injection: what the studies used\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eOn stability, dry formats generally hold up better than solutions, in which hydrolysis and microbial contamination can start. On consistency, a capsule's content is set when powder is blended and filled, so only a content test on individual capsules shows whether fill is even; a liquid depends on full dissolution and accurate measuring. Neither point implies that any format produces an effect.\u003c\/p\u003e\u003ch2\u003eBPC-157 compared with TB-500\u003c\/h2\u003e\u003cp\u003eBPC-157 is often listed alongside TB-500, but they are unrelated molecules with separate literatures.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint\u003c\/th\u003e\n\u003cth\u003eBPC-157\u003c\/th\u003e\n\u003cth\u003eTB-500\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eSequence taken from a protein in human gastric juice\u003c\/td\u003e\n\u003ctd\u003eSynthetic fragment of thymosin beta-4, a 43-residue actin-binding protein found in most cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSize\u003c\/td\u003e\n\u003ctd\u003e15 residues, 1419.5 g\/mol\u003c\/td\u003e\n\u003ctd\u003eA short fragment of a protein of about 4,963 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMain research base\u003c\/td\u003e\n\u003ctd\u003eRodent and cell models, mostly from one group\u003c\/td\u003e\n\u003ctd\u003ePreclinical and early clinical work on the full thymosin beta-4 protein; little on the fragment itself\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman trials\u003c\/td\u003e\n\u003ctd\u003eNo controlled trial published\u003c\/td\u003e\n\u003ctd\u003eEarly trials of full thymosin beta-4 in skin, eye and heart; none of TB-500 as sold\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK status\u003c\/td\u003e\n\u003ctd\u003eUnlicensed, research use only\u003c\/td\u003e\n\u003ctd\u003eUnlicensed, research use only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA section\u003c\/td\u003e\n\u003ctd\u003eS0, non-approved substances\u003c\/td\u003e\n\u003ctd\u003eS2, named with thymosin beta-4 and its derivatives\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThe proposed mechanisms also differ. BPC-157 work has concentrated on gut, tendon and vascular injury models in animals, while thymosin beta-4 binds actin, part of the cell skeleton, and a 2012 review described its study in wound, corneal and cardiac repair models and ongoing or planned clinical trials. Findings for the full protein cannot be assumed to apply to the fragment sold as TB-500, and neither literature can be assumed to transfer to the other peptide. No trial has compared the two. The \u003ca href=\"\/collections\/tb-500\"\u003eTB-500 collection\u003c\/a\u003e lists the brands we hold, and the \u003ca href=\"\/blogs\/news\/tb-500-thymosin-beta-4-research-guide\"\u003eTB-500 and thymosin beta-4 research guide\u003c\/a\u003e summarises its studies. For MK-677 the closest relative is ipamorelin, compared in \u003ca href=\"\/blogs\/news\/mk-677-vs-ipamorelin-vs-hgh\"\u003eMK-677 vs ipamorelin vs somatropin\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eYakka Strength is a third-party brand sold through Muscle Market. For third-party brands we display a certificate of analysis only where the manufacturer supplies one for the exact batch we hold; if none is shown, none has been supplied and we do not substitute a generic document. Free Muscle-brand products, by contrast, are assayed batch by batch at Janoshik Analytical, with the certificate sent on request by email. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e explains what a certificate shows.\u003c\/p\u003e\u003cp\u003eA two-compound bundle should come with two results, one per container. When reading either, check these lines in order:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSample description.\u003c\/strong\u003e The report should name ibutamoren or BPC-157 and describe the sample as capsules. A report headed only with the bundle name leaves open which material was tested.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity method.\u003c\/strong\u003e HPLC compares the time at which a peak leaves the column with a reference standard. LC-MS adds a mass measurement, which is more specific. For ibutamoren the expected mass corresponds to 528.7 g\/mol; for BPC-157, 1419.5 g\/mol.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e The target compound's percentage share of what the instrument detected. It describes cleanliness, not how much is in each capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAssay or content.\u003c\/strong\u003e A milligram figure per capsule would supply what the Yakka Strength label leaves blank. With BPC-157, see whether it is expressed as net peptide or as total powder weight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number, date and laboratory.\u003c\/strong\u003e Set the report's lot code beside the one on the container; a mismatch ends the check there. A dated report from a named laboratory can be followed up.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWhat a missing field means is straightforward. No identity line: nothing confirms the compound. No content line: the strength remains unknown, as it is on this label. No matching batch number: the report describes other material. \u003ca href=\"\/pages\/contact\"\u003eContact us\u003c\/a\u003e with the batch numbers from your containers and we will tell you what exists for current stock. Our article on \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e covers the same lines in more detail.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eBoth compounds are prohibited at all times, in and out of competition, under the World Anti-Doping Code, which UK Anti-Doping enforces for British sport. Ibutamoren appears in section S2 among growth hormone secretagogues. BPC-157 is named in section S0, which covers pharmacological substances with no current approval for human therapeutic use. The anti-doping rule of strict liability means an athlete is responsible for any prohibited substance found in a sample, whatever a label said and whatever the intention.\u003c\/p\u003e\u003cp\u003eNone of the references on this page establishes how long either stays detectable in human urine or blood after exposure, so the accurate statement is: detectable, window not established. The short half-life measured in animals for intact BPC-157 is not a detection window, because testing can target metabolites as well as the parent molecule. Anyone subject to testing should treat exposure to either compound as incompatible with competition.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eNo stability study has been published for either compound in capsule form, so the manufacturer's expiry or best-before date, where printed, is the limit to work to. The two molecules have different weak points. BPC-157, as a peptide, is vulnerable to moisture, because water slowly hydrolyses peptide bonds, and to heat, which speeds that reaction. Ibutamoren has no peptide backbone, but is still best kept from damp, heat and direct light, and capsule shells themselves soften in humidity and turn brittle in dry heat.\u003c\/p\u003e\u003cp\u003eKeep each container tightly closed in a cool, dry and dark place, with any desiccant sachet left inside. If containers are kept in a fridge, allow them to reach room temperature before opening so that condensation does not form on the contents. Keep each compound in its original labelled container so the lot number stays with it. As laboratory reagents they should be handled with gloves once capsules are opened, kept apart from food and drink, stored out of reach of children and animals, and disposed of as chemical waste rather than in household rubbish or drains.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGhrelin\u003c\/strong\u003e: a hormone released mainly by the stomach; its receptor is the target of ibutamoren.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHS-R1a\u003c\/strong\u003e: the growth hormone secretagogue receptor type 1a, the ghrelin receptor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth hormone secretagogue\u003c\/strong\u003e: any compound whose action is to trigger growth hormone release from pituitary stores rather than to replace the hormone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIGF-1\u003c\/strong\u003e: insulin-like growth factor 1; its blood level is the usual marker researchers use to track growth hormone activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePentadecapeptide\u003c\/strong\u003e: from the Greek for fifteen; BPC-157 is so called because its chain has fifteen amino acids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHalf-life\u003c\/strong\u003e: the time taken for the concentration of a substance in blood to fall by half.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBioavailability\u003c\/strong\u003e: the fraction of a dose that reaches the circulation unchanged.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHydrolysis\u003c\/strong\u003e: breakdown of a chemical bond by water; the main route by which peptides degrade in storage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC and LC-MS\u003c\/strong\u003e: laboratory methods that separate a sample; LC-MS also measures molecular mass.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAssay\u003c\/strong\u003e: a measurement of how much of a compound a sample contains, as distinct from its purity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: the anti-doping principle that an athlete is responsible for any prohibited substance in a sample.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/tb-500\"\u003eTB-500 collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-yakka-strength\"\u003eYakka Strength brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/peptides\"\u003ePeptides collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003eResearch articles: \u003ca href=\"\/blogs\/news\/mk-677-ibutamoren-what-the-research-says\"\u003eMK-677: what the research says\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/bpc-157-what-research-shows\"\u003eBPC-157: what research shows\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eNass R, et al. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008;149(9):601-11. PMID: 18981485.\u003c\/li\u003e\n\u003cli\u003eSikiric P, et al. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Curr Neuropharmacol. 2016;14(8):857-865. PMID: 27138887.\u003c\/li\u003e\n\u003cli\u003eHe L, et al. Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs. Front Pharmacol. 2022;13:1026182. PMID: 36588717.\u003c\/li\u003e\n\u003cli\u003eGoldstein AL, et al. Thymosin beta4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther. 2012;12(1):37-51. PMID: 22074294.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Yakka Strength","offers":[{"title":"Default Title","offer_id":48468982366434,"sku":null,"price":111.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/yakka-strength-research-capsule-bundle-front-g_600x_c5de8613-da5f-4500-939b-b383c4161ef4.png?v=1789931442"},{"product_id":"yakka-strength-yakka-strength-mk677-tb500-capsule-bundle","title":"Yakka Strength MK-677 \u0026 TB-500 Capsule Bundle","description":"\u003cp\u003eThe Yakka Strength MK-677 and TB-500 capsule bundle lists ibutamoren (MK-677), a growth hormone secretagogue, together with TB-500, a synthetic fragment of thymosin beta-4, from one manufacturer in a single order through our \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e range. Yakka Strength lists the pack as 60 capsules. No content per capsule is stated by the manufacturer on this listing, so we do not quote one. Supplied to adults for laboratory research only and not for human consumption.\u003c\/p\u003e\u003cp\u003eA bundle is a listing convenience only: it lets separately packaged products from one manufacturer be ordered in a single purchase. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eMK-677 (Ibutamoren)\u003c\/h3\u003e\u003cp\u003eIbutamoren (MK-677, L-163,191, nutrobal) is not a SARM but an orally active ghrelin receptor (GHS-R1a) agonist, a growth hormone secretagogue. Unusually for this market it has real human data. A one-year randomised trial in healthy older adults reported sustained rises in growth hormone and IGF-1, a 1.1 kg rise in fat-free mass against a 0.5 kg fall with placebo, but no change in strength or function, alongside increased appetite, mild leg swelling from fluid retention, muscle pain, higher fasting glucose, reduced insulin sensitivity and a rise in cortisol. Never approved. WADA class S2. Compare brands on the \u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eA later phase IIb trial tested the compound, under the code MK-0677, in 123 older patients recovering from hip fracture. Blood IGF-1 rose clearly against placebo and gait speed improved modestly, but most other measures of physical function did not change, and the study was stopped early after a small number of patients developed congestive heart failure. The authors concluded that the compound had an unfavourable safety profile in that population.\u003c\/p\u003e\u003ch3\u003eTB-500 (Thymosin Beta-4 fragment)\u003c\/h3\u003e\u003cp\u003eTB-500 is the market name for a synthetic fragment of thymosin beta-4, a 43-amino-acid actin-binding peptide made in the body. Reviews of thymosin beta-4 cover preclinical wound, corneal and cardiac repair models and early clinical trials of the full peptide. TB-500 itself has no published human data. WADA names thymosin beta-4 and its derivatives, including TB-500, under S2. Compare brands on the \u003ca href=\"\/collections\/tb-500\"\u003eTB-500 (Thymosin Beta-4 fragment) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eWhat TB-500 actually contains was settled analytically rather than clinically. In 2012 the Ghent anti-doping laboratory examined a product sold as TB-500 by high-resolution mass spectrometry and found the acetylated 17-23 fragment of thymosin beta-4, Ac-LKKTETQ, a seven-residue peptide, instead of the whole protein. So a TB-500 label and the thymosin beta-4 literature need not describe the same molecule.\u003c\/p\u003e\u003ch3\u003eAt a glance\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint\u003c\/th\u003e\n\u003cth\u003eIbutamoren (MK-677)\u003c\/th\u003e\n\u003cth\u003eTB-500\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eChemical class\u003c\/td\u003e\n\u003ctd\u003eSpiro-piperidine small molecule, no peptide bonds\u003c\/td\u003e\n\u003ctd\u003ePeptide, usually the acetylated seven-residue fragment\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula (PubChem)\u003c\/td\u003e\n\u003ctd\u003eC27H36N4O5S, 528.7 g\/mol, CAS 159634-47-6\u003c\/td\u003e\n\u003ctd\u003eParent protein C212H350N56O78S, about 4,963 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTarget\u003c\/td\u003e\n\u003ctd\u003eGhrelin receptor on the pituitary\u003c\/td\u003e\n\u003ctd\u003eBinds G-actin inside cells (parent protein)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman trial data\u003c\/td\u003e\n\u003ctd\u003eYes, randomised, taken by mouth\u003c\/td\u003e\n\u003ctd\u003eNone for TB-500; limited for the full protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA section\u003c\/td\u003e\n\u003ctd\u003eS2\u003c\/td\u003e\n\u003ctd\u003eS2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: Yakka Strength (third-party brand, Muscle Market)\u003c\/li\u003e\n\u003cli\u003eCompounds: ibutamoren (MK-677) and TB-500 (thymosin beta-4 fragment)\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eContent per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eWhich TB-500 molecule: not stated on the label\u003c\/li\u003e\n\u003cli\u003eCOA: only where Yakka Strength supplies one for the batch held\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eBecause neither compound carries a stated content, milligrams per pack cannot be worked out and the bundle cannot be compared with single packs on cost per milligram; our \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram guide\u003c\/a\u003e sets out the method for products that do state a strength. The same manufacturer's \u003ca href=\"\/products\/yakka-strength-yakka-strength-mk677\"\u003eMK-677 capsules\u003c\/a\u003e and \u003ca href=\"\/products\/yakka-strength-yakka-strength-tb500-peptide-capsules\"\u003eTB-500 capsules\u003c\/a\u003e are also listed on their own.\u003c\/p\u003e\u003ch2\u003eMK-677 and TB-500 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"MK677 UK buy\" and \"MK 677 UK legal\" ask two things: is the purchase lawful, and can the seller show what is in the container.\u003c\/p\u003e\u003ch3\u003eWhere the law stands\u003c\/h3\u003e\u003cp\u003eNone of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement. MK-677 and TB-500 are not controlled substances in the UK, but that is not approval: neither may lawfully be marketed for people to take. Free Muscle supplies them to adults aged 18 and over for laboratory research only. They are not for human consumption. Both MK-677 and TB-500 fall under WADA class S2. See our \u003ca href=\"\/pages\/mk-677-legal-status-uk\"\u003eMK-677 legal status page\u003c\/a\u003e. Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e has more background.\u003c\/p\u003e\u003ch3\u003eSigns of a listing worth trusting\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated strength for each compound\u003c\/strong\u003e, or an open statement that the manufacturer gives none.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe exact molecule named\u003c\/strong\u003e: for TB-500 that means saying whether it is the Ac-LKKTETQ fragment or full thymosin beta-4.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA lot number printed on each container\u003c\/strong\u003e and repeated on the certificate that goes with it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate per compound per batch\u003c\/strong\u003e, from a named laboratory, not a single report headed with the bundle name.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-only wording\u003c\/strong\u003e: 18+, no instructions, no promised outcomes, no before-and-after images.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA UK company you can write to\u003c\/strong\u003e, tracked delivery, plain packaging and a published returns policy.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eHow this listing measures up\u003c\/h3\u003e\u003cp\u003eThe seller side is met. FreeMuscle LTD is a UK company based in Scunthorpe; every order ships by free tracked UK delivery in plain packaging, orders placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3-7 working days, and unopened items can be returned within 30 days. The product side depends on Yakka Strength. The label names both compounds but states no content for either and does not say which TB-500 molecule is used, so those checks are not met from the label alone. A certificate is shown only where the manufacturer supplies one for the batch we hold. The full set of checks is in our \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eIn the UK research market ibutamoren is found as capsules, tablets and liquid (\"MK677 UK liquid\" is a frequent search), while TB-500 is most often sold as freeze-dried powder in vials, with capsules a more recent format. The molecule is the same; the evidence behind each route is not.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIbutamoren.\u003c\/strong\u003e Merck designed it as a non-peptide precisely so that it would remain active when swallowed, and both trials summarised above gave it by mouth. A capsule is therefore the route its literature actually studied. In a liquid, hydrolysis, evaporation and incomplete dissolution can shift the concentration; a capsule fixes its fill at manufacture, so its consistency rests on how evenly the powder was blended.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTB-500.\u003c\/strong\u003e Here the capsule is the unusual choice. The thymosin beta-4 programmes used injection or direct application to eye, skin or heart tissue, and no published study has given either the full protein or the Ac-LKKTETQ fragment by mouth and measured it in blood. Peptides face digestive enzymes that cut the bonds between amino acids. Our article \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides actually work?\u003c\/a\u003e sets out what is and is not known about oral peptide absorption. None of this implies that any format produces an effect.\u003c\/p\u003e\u003ch2\u003eTB-500 compared with BPC-157, and MK-677 with ipamorelin\u003c\/h2\u003e\u003cp\u003eEach compound in this bundle has one relative it is searched against far more than any other: \"TB 500 vs BPC 157\" and \"ibutamoren vs ipamorelin\".\u003c\/p\u003e\u003ch3\u003eTB-500 and BPC-157\u003c\/h3\u003e\u003cp\u003eThe two peptides are often shelved together, but they share neither origin nor mechanism. TB-500 traces back to thymosin beta-4, a protein that sits inside cells and holds single actin units in reserve. BPC-157 is a 15-amino-acid sequence taken from a protein found in gastric juice, and nearly all of its published work comes from rodent gut, tendon and blood vessel models. Neither peptide has a published controlled human trial. The clearest practical difference is definition: BPC-157 is one fixed sequence, so identity testing is simple, whereas \"TB-500\" has been applied to more than one molecule, so a certificate has to say which it found. The two also sit in different parts of the WADA list, TB-500 under S2 and BPC-157 under S0 for non-approved substances. Brands we hold are in the \u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eMK-677 and ipamorelin\u003c\/h3\u003e\u003cp\u003eHere the comparison is closer, because both act at the same ghrelin receptor and prompt the pituitary to release growth hormone it already stores. The differences are structure and evidence. Ibutamoren is a small molecule tested by mouth in randomised human trials, with the adverse findings described above. Ipamorelin is a five-residue peptide developed by Novo Nordisk in the 1990s, studied mostly by injection and with a far thinner human literature. Neither is licensed in the UK and WADA lists both under S2. Brands are in the \u003ca href=\"\/collections\/ipamorelin\"\u003eipamorelin collection\u003c\/a\u003e, and the \u003ca href=\"\/blogs\/news\/mk-677-vs-ipamorelin-vs-hgh\"\u003eMK-677 vs ipamorelin vs somatropin\u003c\/a\u003e article covers the question in depth.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eYakka Strength is a third-party brand sold through Muscle Market. For third-party brands we display a certificate of analysis only where the manufacturer supplies one for the exact batch we hold; if none is shown, none has been supplied and we do not substitute a generic document. Free Muscle-brand products, by contrast, are assayed batch by batch at Janoshik Analytical, with the certificate sent on request by email. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e explains what a certificate shows.\u003c\/p\u003e\u003cp\u003eExpect two reports, one per compound, and read each against its own container.\u003c\/p\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity.\u003c\/strong\u003e HPLC compares a peak with a reference standard; LC-MS also measures the mass, which is the firmer evidence. Ibutamoren, at 528.7 g\/mol, should appear as a protonated ion close to m\/z 529. For TB-500 the mass tells you which molecule is present: the Ac-LKKTETQ fragment weighs roughly 889 g\/mol, while full thymosin beta-4 is near 4,963 g\/mol and shows as a cluster of multiply charged ions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity (%).\u003c\/strong\u003e The main compound's share of the chromatogram. It measures how clean the material is, not how much is in each capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAssay.\u003c\/strong\u003e Milligrams found per capsule, the one figure that would replace the missing label strength; peptide results may be given as net peptide or as gross powder weight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number.\u003c\/strong\u003e It has to match the lot printed on that container; a different number means the report describes other stock.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest date and laboratory.\u003c\/strong\u003e The test date should fall after the batch was made, and the laboratory should be named so the report can be checked with it.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003eFor this brand, a missing identity line leaves the TB-500 question open, a missing content line leaves both strengths unknown, and a report headed only \"MK-677 and TB-500 bundle\" cannot show which compound was tested. \u003ca href=\"\/pages\/contact\"\u003eContact us\u003c\/a\u003e with the lot numbers and we will say what exists for current stock. See also \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eBoth compounds are prohibited at all times, in and out of competition, under the World Anti-Doping Code, which UK Anti-Doping applies in this country. Ibutamoren is named in section S2 among the growth hormone secretagogues; TB-500 falls under the same section through the entry for thymosin beta-4 and its derivatives. Under strict liability a competitor is answerable for anything found in their sample. A research-use label or a certificate of analysis offers no defence in an anti-doping case.\u003c\/p\u003e\u003cp\u003eAnti-doping laboratories have worked on TB-500 for over a decade. The 2012 Ghent study that identified the Ac-LKKTETQ fragment also proposed an LC-MS\/MS strategy for finding it in plasma and urine. No study cited on this page reports how long either ibutamoren or TB-500 remains detectable in human urine after exposure, so the accurate statement for both is: detectable, window not established. Anyone who is subject to testing should assume that contact with either compound will be found.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eNo published stability study covers either compound in capsule form, so the expiry or best-before date printed by the manufacturer, where one is given, is the limit to work within. The two compounds are vulnerable in different ways. For ibutamoren the main risks come from the capsule itself: humidity softens gelatin and clumps powder. TB-500 is a peptide, so water is the bigger concern, since it breaks peptide bonds over time; the full thymosin beta-4 protein also carries a methionine that oxidises easily, a reaction light can accelerate.\u003c\/p\u003e\u003cp\u003eIn practice: keep the containers sealed in a cool, dry, dark cupboard, away from bathrooms and radiators. Leave any desiccant sachet in place. If stock is kept in a fridge, allow the container to reach room temperature before opening so moisture does not condense on the capsules. Store each compound in its own labelled container so that it stays tied to its lot number and certificate. Treat the contents as laboratory reagents: wear gloves when handling opened capsules, keep them apart from food and drink and out of reach of children and pets, and dispose of unwanted material as chemical waste rather than in household bins or drains.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIbutamoren\u003c\/strong\u003e: the international name for MK-677, also coded L-163,191 and MK-0677.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGhrelin receptor (GHS-R1a)\u003c\/strong\u003e: the receptor on pituitary cells that ibutamoren and ipamorelin activate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIGF-1\u003c\/strong\u003e: insulin-like growth factor 1, whose blood level rose in both ibutamoren trials.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhase IIb trial\u003c\/strong\u003e: a mid-stage study of a candidate medicine in patients with the target condition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThymosin beta-4\u003c\/strong\u003e: a 43-amino-acid protein present in most cells; TB-500 products are based on it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAc-LKKTETQ\u003c\/strong\u003e: the acetylated seven-residue fragment (positions 17 to 23) of thymosin beta-4 found in TB-500 by anti-doping analysts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eG-actin\u003c\/strong\u003e: single, unpolymerised units of actin, the protein that builds a cell's internal scaffolding.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMass spectrometry\u003c\/strong\u003e: weighing ionised molecules, reported as m\/z, to confirm what a sample is.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNet peptide content\u003c\/strong\u003e: the share of a peptide powder that is the peptide itself, excluding water and counter-ions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWADA S2\u003c\/strong\u003e: the Prohibited List section for peptide hormones, growth factors, related substances and mimetics.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/tb-500\"\u003eTB-500 (Thymosin Beta-4) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-yakka-strength\"\u003eYakka Strength brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/peptides\"\u003ePeptides collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003eResearch articles: \u003ca href=\"\/blogs\/news\/mk-677-ibutamoren-what-the-research-says\"\u003eMK-677: what the research says\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/tb-500-thymosin-beta-4-research-guide\"\u003eTB-500 and thymosin beta-4 research guide\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eNass R, et al. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008;149(9):601-11. PMID: 18981485.\u003c\/li\u003e\n\u003cli\u003eAdunsky A, et al. MK-0677 (ibutamoren mesylate) for the treatment of patients recovering from hip fracture: a multicenter, randomized, placebo-controlled phase IIb study. Arch Gerontol Geriatr. 2011;53(2):183-9. PMID: 21067829.\u003c\/li\u003e\n\u003cli\u003eGoldstein AL, et al. Thymosin beta4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther. 2012;12(1):37-51. PMID: 22074294.\u003c\/li\u003e\n\u003cli\u003eEsposito S, et al. Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential. Drug Test Anal. 2012;4(9):733-8. PMID: 22962027.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Yakka Strength","offers":[{"title":"Default Title","offer_id":48468982595810,"sku":null,"price":116.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/yakka-strength-research-capsule-bundle-front-f_600x_561eea53-9aa9-4013-b614-e55dc15f7cf3.png?v=1789931444"},{"product_id":"yakka-strength-yakka-strength-mk677-bpc157-tb500-capsule-bundle","title":"Yakka Strength MK-677 + BPC-157 + TB-500 Capsule Bundle","description":"\u003cp\u003eThe Yakka Strength MK-677, BPC-157 and TB-500 capsule bundle brings together one growth hormone secretagogue, ibutamoren (MK-677), and two research peptides, BPC-157 and TB-500, all from the same manufacturer and stocked in our \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e range. Yakka Strength lists the pack as 60 capsules and states no content per capsule, so we quote none. Supplied to adults for laboratory research only, not for human consumption.\u003c\/p\u003e\u003cp\u003eA bundle is a listing convenience only: it lets products from one manufacturer be ordered in a single purchase. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eMK-677 (Ibutamoren)\u003c\/h3\u003e\u003cp\u003eIbutamoren (MK-677, L-163,191, nutrobal) is not a SARM but an orally active ghrelin receptor (GHS-R1a) agonist, a growth hormone secretagogue. Unusually for this market it has real human data. A two-year randomised trial in healthy older adults reported, at one year, sustained rises in growth hormone and IGF-1, about 1 kg more fat-free mass than placebo and no gain in strength or function, alongside increased appetite, fluid retention, higher fasting glucose and reduced insulin sensitivity. Never approved. WADA class S2. Compare brands on the \u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eBPC-157\u003c\/h3\u003e\u003cp\u003eBPC-157 is a synthetic fifteen-amino-acid peptide based on a sequence from a human gastric protein. Almost all published work is rodent and cell research, largely from one Croatian group, covering animal models of gut, tendon, muscle and vascular injury. No controlled human trial has been published, and oral absorption of any peptide is unproven. WADA lists it under S0 (non-approved substances). Compare brands on the \u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eTB-500 (Thymosin Beta-4 fragment)\u003c\/h3\u003e\u003cp\u003eTB-500 is the trade name for a synthetic fragment of thymosin beta-4, a 43-amino-acid actin-binding peptide present in most human and animal cells. Reviews of thymosin beta-4 cover preclinical wound, corneal and cardiac repair models and early clinical trials of the full peptide. TB-500 itself has no published human data. WADA names thymosin beta-4 and its derivatives, including TB-500, under S2. Compare brands on the \u003ca href=\"\/collections\/tb-500\"\u003eTB-500 (Thymosin Beta-4 fragment) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eThe three molecules side by side\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIdentifier\u003c\/th\u003e\n\u003cth\u003eIbutamoren\u003c\/th\u003e\n\u003cth\u003eBPC-157\u003c\/th\u003e\n\u003cth\u003eThymosin beta-4 (parent of TB-500)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eType\u003c\/td\u003e\n\u003ctd\u003eNon-peptide small molecule\u003c\/td\u003e\n\u003ctd\u003e15-residue peptide\u003c\/td\u003e\n\u003ctd\u003e43-residue protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular formula\u003c\/td\u003e\n\u003ctd\u003eC27H36N4O5S\u003c\/td\u003e\n\u003ctd\u003eC62H98N16O22\u003c\/td\u003e\n\u003ctd\u003eC212H350N56O78S\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e528.7 g\/mol\u003c\/td\u003e\n\u003ctd\u003e1419.5 g\/mol\u003c\/td\u003e\n\u003ctd\u003eabout 4,963 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e159634-47-6\u003c\/td\u003e\n\u003ctd\u003e137525-51-0\u003c\/td\u003e\n\u003ctd\u003enone in our PubChem record\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e178024\u003c\/td\u003e\n\u003ctd\u003e9941957\u003c\/td\u003e\n\u003ctd\u003e45382195\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThe size gap, roughly tenfold, shapes how each is delivered, identified and detected. The two peptides are in capsule form. Oral absorption of peptides is unproven, a point covered in our article \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides actually work?\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: Yakka Strength (third-party brand, Muscle Market)\u003c\/li\u003e\n\u003cli\u003eCompounds: ibutamoren (MK-677), BPC-157, TB-500\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eContent per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eCOA: only where Yakka Strength supplies one for the batch held\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over, for laboratory research only\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWithout a stated content for any of the three compounds, milligrams per pack cannot be calculated, so this bundle cannot be set against single-compound packs on cost per milligram (the method is explained in \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e). Yakka Strength also lists \u003ca href=\"\/products\/yakka-strength-yakka-strength-mk677\"\u003eMK-677\u003c\/a\u003e, \u003ca href=\"\/products\/yakka-strength-yakka-strength-bpc157-peptide-capsules\"\u003eBPC-157\u003c\/a\u003e and \u003ca href=\"\/products\/yakka-strength-yakka-strength-tb500-peptide-capsules\"\u003eTB-500\u003c\/a\u003e singly.\u003c\/p\u003e\u003ch2\u003eMK-677, BPC-157 and TB-500 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"MK677 UK buy\", \"BPC 157 UK legal\" and \"BPC157 TB500 UK\" ask two things: can these be bought lawfully here, and does the seller document what it sells?\u003c\/p\u003e\u003ch3\u003eThe legal position for each compound\u003c\/h3\u003e\u003cp\u003eNone of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement. None is a controlled drug either, which is why they can be supplied at all, but lack of control is not approval: they cannot lawfully be sold for human consumption under any heading. Free Muscle supplies them to adults aged 18 and over for laboratory research only. None is available on prescription. MK-677 and TB-500 fall under WADA class S2, and BPC-157 under S0. Buyers are responsible for the rules that apply to them, including any anti-doping code. See our \u003ca href=\"\/pages\/mk-677-legal-status-uk\"\u003eMK-677 legal status page\u003c\/a\u003e. Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e has more background.\u003c\/p\u003e\u003ch3\u003eWhat a bundle listing should document\u003c\/h3\u003e\u003cp\u003eEvery claim on a bundle has to hold for each compound separately. A well-documented UK bundle listing shows:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEach compound named properly\u003c\/strong\u003e, with the manufacturer identified.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA lot number on every container\u003c\/strong\u003e, since a certificate can only be tied to material that carries its number.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA separate certificate for each compound\u003c\/strong\u003e; a report on the MK-677 capsules proves nothing about the peptides, and the reverse.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated content per capsule for each compound\u003c\/strong\u003e, or a clear note that the manufacturer gives none.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSale terms that match research supply\u003c\/strong\u003e: an 18+ restriction and no directions or outcome claims.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA traceable UK company\u003c\/strong\u003e, tracked delivery, plain packaging and published returns terms.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eWhere this listing stands\u003c\/h3\u003e\u003cp\u003eFreeMuscle LTD is a UK company in Scunthorpe, the manufacturer is named, and every order goes by free tracked UK delivery in plain packaging. Orders placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3-7 working days, and unopened items can be returned within 30 days. The compound points rest with Yakka Strength. The label states no content for any of the three, so that check is not met, and a certificate is shown only where the manufacturer supplies one for the batch we hold. Reviews and forum threads cannot close either gap: they record impressions, not measured content. Our \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e sets out the full list of checks.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eAll three compounds circulate as capsules, tablets and liquids, and the two peptides also as freeze-dried powder in vials. The molecule is the same in each; what differs is whether research used that route and how the material keeps.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIbutamoren\u003c\/strong\u003e is the exception in this bundle. It was designed by Merck as a non-peptide so that it would remain active when swallowed, and the controlled trials cited here gave it by mouth.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157\u003c\/strong\u003e was mostly given by injection into the abdominal cavity in rodent work, with some studies adding it to drinking water. No study has measured blood levels in people after a capsule, and the question is examined in \u003ca href=\"\/blogs\/news\/bpc-157-capsules-vs-injection-what-studies-used\"\u003eBPC-157 capsules vs injection: what the studies used\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500 and thymosin beta-4\u003c\/strong\u003e were studied by injection or local application to eye, skin or heart tissue. No oral study of either has been published.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eFor the peptides the obstacle is digestion: pepsin, trypsin, chymotrypsin and brush-border peptidases split peptide bonds, and short linear chains are routine substrates. Ibutamoren has no peptide bonds for them to cut.\u003c\/p\u003e\u003cp\u003eDry formats generally keep better than solutions, where hydrolysis and microbial growth can start. A capsule's content is fixed at blending and filling, so its consistency depends on the blend, which only a per-capsule content test shows; a liquid's depends on complete dissolution and accurate measuring. None of this implies that any format produces an effect.\u003c\/p\u003e\u003ch2\u003eMK-677 compared with ipamorelin\u003c\/h2\u003e\u003cp\u003eThe compound most often searched against MK-677 is ipamorelin (\"ibutamoren vs ipamorelin\"). The two peptides in this bundle act by unrelated mechanisms, whereas ipamorelin shares MK-677's receptor, which makes it the useful reference point.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint\u003c\/th\u003e\n\u003cth\u003eIbutamoren (MK-677)\u003c\/th\u003e\n\u003cth\u003eIpamorelin\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eStructure\u003c\/td\u003e\n\u003ctd\u003eNon-peptide small molecule\u003c\/td\u003e\n\u003ctd\u003eFive-residue peptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and weight\u003c\/td\u003e\n\u003ctd\u003eC27H36N4O5S, 528.7 g\/mol\u003c\/td\u003e\n\u003ctd\u003eC38H49N9O5, 711.9 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDeveloper\u003c\/td\u003e\n\u003ctd\u003eMerck, 1990s\u003c\/td\u003e\n\u003ctd\u003eNovo Nordisk, described in 1998\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReceptor\u003c\/td\u003e\n\u003ctd\u003eGhrelin receptor, GHS-R1a\u003c\/td\u003e\n\u003ctd\u003eThe same receptor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRoute in published studies\u003c\/td\u003e\n\u003ctd\u003eBy mouth, in randomised human trials\u003c\/td\u003e\n\u003ctd\u003eInjection in the original animal pharmacology\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK status\u003c\/td\u003e\n\u003ctd\u003eUnlicensed research compound\u003c\/td\u003e\n\u003ctd\u003eUnlicensed research compound\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eS2, growth hormone secretagogues\u003c\/td\u003e\n\u003ctd\u003eS2, growth hormone secretagogues\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eMechanism is where they meet. Both bind the ghrelin receptor on the pituitary and release growth hormone the gland already holds, rather than supplying hormone from outside. The 1998 paper from Novo Nordisk that introduced ipamorelin described it as the first selective secretagogue: in conscious swine it released growth hormone with a potency similar to the older peptide GHRP-6, but unlike GHRP-6 and GHRP-2 it did not raise ACTH or cortisol beyond the levels seen with growth hormone releasing hormone. That is an animal finding, not a human one.\u003c\/p\u003e\u003cp\u003eEvidence is where they part. Ibutamoren has randomised human trials with recorded adverse findings; ipamorelin's human literature is much thinner, and a PubMed search combining the two names returns no randomised trial comparing them, so neither can be ranked above the other. Brands held are in the \u003ca href=\"\/collections\/ipamorelin\"\u003eipamorelin collection\u003c\/a\u003e, the two are set against prescription somatropin in \u003ca href=\"\/blogs\/news\/mk-677-vs-ipamorelin-vs-hgh\"\u003eMK-677 vs ipamorelin vs somatropin\u003c\/a\u003e, and the peptide's own studies are in the \u003ca href=\"\/blogs\/news\/ipamorelin-research-guide\"\u003eipamorelin research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eYakka Strength is a third-party brand sold through Muscle Market. For third-party brands we display a certificate of analysis only where the manufacturer supplies one for the exact batch we hold; if none is shown, none has been supplied and we do not substitute a generic document. Free Muscle-brand products, by contrast, are assayed batch by batch at Janoshik Analytical, with the certificate sent on request by email. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e explains what a certificate shows.\u003c\/p\u003e\u003cp\u003eThree compounds means three results. Read each against its container:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhich compound.\u003c\/strong\u003e A result headed only with the bundle name cannot show which of the three was measured.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity, by HPLC or LC-MS.\u003c\/strong\u003e HPLC matches a peak to a reference standard's retention time; LC-MS also weighs it, which is firmer. The expected masses differ widely: ibutamoren gives a protonated ion near m\/z 529, BPC-157 has a molecular weight of about 1419.5, and TB-500 should match the mass of the fragment stated on the report, far below the full 4,963 g\/mol protein.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity (%).\u003c\/strong\u003e The compound's share of the chromatogram: cleanliness, not quantity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e The only line that can supply the figure this label leaves out. For peptides, check whether it reports net peptide or total powder.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number, test date and laboratory.\u003c\/strong\u003e Check the number against the lot printed on that compound's container; a named laboratory and a dated report can be checked, an anonymous one cannot.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWithout an identity line nothing confirms the compound; without a content line the strength stays unknown; without a matching batch number the report describes other material. \u003ca href=\"\/pages\/contact\"\u003eContact us\u003c\/a\u003e with the batch numbers and we will say what exists for current stock. See also \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eAll three compounds are prohibited at all times, in and out of competition, under the World Anti-Doping Code, which UK Anti-Doping applies in this country. They sit in different sections. Ibutamoren is named among the growth hormone secretagogues in S2. TB-500 falls under S2 because the list names thymosin beta-4 and its derivatives. BPC-157 is named in S0, the section for substances with no current approval for human therapeutic use. Strict liability applies: an athlete answers for any prohibited substance in a sample, whatever the label said.\u003c\/p\u003e\u003cp\u003eFor BPC-157, the Salt Lake City anti-doping laboratory published a validated urine method in 2017 with a limit of detection of 0.1 ng\/mL, found the peptide stable in urine for at least four days, and made the test more specific by measuring a stable metabolite alongside it. None of the studies cited on this page sets out how long any of the three compounds remains detectable in human urine after exposure, so the accurate statement for each is: detectable, window not established. Anyone subject to testing should assume that exposure to any compound in this bundle will be found.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eNo published stability study covers any of these compounds in capsule form, so the expiry or best-before date printed by the manufacturer, where there is one, is the limit to work to. For the two peptides, moisture is the main threat, because water hydrolyses peptide bonds. Full thymosin beta-4 also contains a methionine residue, which oxidises readily, a process light can speed up. For all three, damp softens capsule shells and clumps powder, while dry heat makes shells brittle.\u003c\/p\u003e\u003cp\u003eKeep each container closed in a cool, dry, dark cupboard, away from radiators and steamy rooms, with any desiccant left in place. If containers are refrigerated, let them reach room temperature before opening so condensation does not form inside. Keep the contents in the original, lot-numbered packaging and note the date of first opening. Handle the contents as laboratory reagents: gloves for opened capsules, separation from food and drink, storage out of reach of children and animals, and disposal as chemical waste rather than in household bins or drains.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth hormone secretagogue\u003c\/strong\u003e: a substance that causes the pituitary gland to release more of its own growth hormone; ibutamoren and ipamorelin are both examples.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHS-R1a\u003c\/strong\u003e: the receptor for the stomach hormone ghrelin, found on the pituitary and elsewhere; ibutamoren binds it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIGF-1\u003c\/strong\u003e: insulin-like growth factor 1, a hormone made mainly in the liver whose blood level follows growth hormone output.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePentadecapeptide\u003c\/strong\u003e: a peptide of 15 amino acids, which is how BPC-157 is described.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThymosin beta-4\u003c\/strong\u003e: the full 43-residue actin-binding protein from which the TB-500 fragment is taken.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePeptidase\u003c\/strong\u003e: any enzyme that splits a peptide chain; pepsin and trypsin are two of the digestive ones.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetention time\u003c\/strong\u003e: the point at which a compound emerges from an HPLC column; a match with a reference standard supports, but does not prove, identity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eS0 and S2\u003c\/strong\u003e: WADA list sections; S0 catches substances with no human therapeutic approval, S2 covers peptide hormones, growth factors and their releasing agents.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: under the anti-doping code, a banned substance in a sample counts as a violation regardless of intent or labelling.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/tb-500\"\u003eTB-500 (Thymosin Beta-4) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/ipamorelin\"\u003eIpamorelin collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-yakka-strength\"\u003eYakka Strength brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003eResearch articles: \u003ca href=\"\/blogs\/news\/mk-677-ibutamoren-what-the-research-says\"\u003eMK-677\u003c\/a\u003e, \u003ca href=\"\/blogs\/news\/bpc-157-what-research-shows\"\u003eBPC-157\u003c\/a\u003e, \u003ca href=\"\/blogs\/news\/tb-500-thymosin-beta-4-research-guide\"\u003eTB-500\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eNass R, et al. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008;149(9):601-11. PMID: 18981485.\u003c\/li\u003e\n\u003cli\u003eSikiric P, et al. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Curr Neuropharmacol. 2016;14(8):857-865. PMID: 27138887.\u003c\/li\u003e\n\u003cli\u003eGoldstein AL, et al. Thymosin beta4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther. 2012;12(1):37-51. PMID: 22074294.\u003c\/li\u003e\n\u003cli\u003eRaun K, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-61. PMID: 9849822.\u003c\/li\u003e\n\u003cli\u003eCox HD, et al. Detection and in vitro metabolism of the confiscated peptides BPC 157 and MGF R23H. Drug Test Anal. 2017;9(10):1490-1498. PMID: 28035768.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Yakka Strength","offers":[{"title":"Default Title","offer_id":48468982628578,"sku":null,"price":165.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/yakka-strength-research-capsule-bundle-front-e_600x_43ada6d6-ab80-4b0e-8fc1-9c7c88a8813d.png?v=1789931445"},{"product_id":"yakka-strength-yakka-strength-mk677-rad140","title":"Yakka Strength MK-677 + RAD-140","description":"\u003cp\u003eThe Yakka Strength MK-677 and RAD-140 bundle lists a growth hormone secretagogue, ibutamoren (MK-677), alongside a selective androgen receptor modulator, testolone (RAD-140), in one order from a single manufacturer. Yakka Strength lists the pack as 60 capsules. No strength per capsule is stated by the manufacturer on this listing, so none is quoted here. Supplied to adults for laboratory research only and not for human consumption, through the \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e range.\u003c\/p\u003e\u003cp\u003eThis bundle exists purely for ordering convenience: two separately packaged Yakka Strength products bought in one transaction. No claim is made here that the two compounds interact or belong in the same study, and Free Muscle publishes no stack or cycle guidance for any product.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003cp\u003eThe two molecules share a format and a manufacturer, and little else: one prompts the pituitary through the ghrelin receptor, the other binds the androgen receptor in tissue. PubChem identifiers:\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIdentifier\u003c\/th\u003e\n\u003cth\u003eMK-677\u003c\/th\u003e\n\u003cth\u003eRAD-140\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOther names\u003c\/td\u003e\n\u003ctd\u003eIbutamoren, L-163,191, Nutrobal\u003c\/td\u003e\n\u003ctd\u003eTestolone, vosilasarm, EP0062\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eClass\u003c\/td\u003e\n\u003ctd\u003eGrowth hormone secretagogue\u003c\/td\u003e\n\u003ctd\u003eNon-steroidal SARM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e159634-47-6\u003c\/td\u003e\n\u003ctd\u003e1182367-47-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular formula\u003c\/td\u003e\n\u003ctd\u003eC27H36N4O5S\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e528.7 g\/mol\u003c\/td\u003e\n\u003ctd\u003e393.8 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e178024\u003c\/td\u003e\n\u003ctd\u003e44200882\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA class\u003c\/td\u003e\n\u003ctd\u003eS2\u003c\/td\u003e\n\u003ctd\u003eS1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch3\u003eMK-677 (Ibutamoren)\u003c\/h3\u003e\u003cp\u003eIbutamoren (MK-677, L-163,191, nutrobal) is not a SARM but an orally active ghrelin receptor (GHS-R1a) agonist, a growth hormone secretagogue. Unusually for this market it has real human data. A one-year randomised trial in healthy older adults reported sustained rises in growth hormone and IGF-1, a mean fat-free mass gain of 1.1 kg against a 0.5 kg fall with placebo and no change in strength or function, alongside increased appetite, fluid retention, higher fasting glucose and reduced insulin sensitivity. Never approved. WADA class S2. Compare brands on the \u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eTestolone (RAD-140)\u003c\/h3\u003e\u003cp\u003eTestolone (RAD-140) is a non-steroidal SARM designed by Radius Health, characterised in preclinical animal models. Human data are limited to a small early oncology study, and it has not been approved for any use. That first-in-human trial, published in 2022, enrolled 22 postmenopausal women with advanced hormone receptor-positive breast cancer. Raised liver enzymes were its most frequent adverse events, and 16 of the 22 women had an event graded 3 or 4. Sex hormone-binding globulin fell and prostate-specific antigen rose in most participants tested, a sign of androgen receptor activity well beyond muscle, and the elimination half-life was measured at 44.7 hours.\u003c\/p\u003e\u003cp\u003ePublished case reports describe drug-induced liver injury in adults who had taken products labelled RAD-140. In one, from a Veterans Affairs hospital in California, a 24-year-old man presented with jaundice and itching; biopsy showed a cholestatic pattern of injury, and it resolved after the product was stopped. It has never been approved as a medicine. WADA class S1. Compare brands on the \u003ca href=\"\/collections\/rad-140\"\u003eTestolone (RAD-140) collection page\u003c\/a\u003e. None of these findings, for either compound, is a claim about this product.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: Yakka Strength (third-party brand, Muscle Market)\u003c\/li\u003e\n\u003cli\u003eCompounds: ibutamoren (MK-677) and testolone (RAD-140)\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eCOA: only where Yakka Strength supplies one for the batch held\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eBecause neither compound carries a printed milligram figure, the total per pack cannot be worked out and the bundle cannot be set against single-compound listings on \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e. A measured content can only come from a batch certificate, covered further down.\u003c\/p\u003e\u003ch2\u003eMK-677 and RAD-140 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"mk677 rad140 uk\", \"rad140 for sale uk\" and \"mk 677 uk legal\" ask two things: may these compounds lawfully be bought in Britain, and how is a reliable listing recognised? For a bundle, each answer is needed twice.\u003c\/p\u003e\u003ch3\u003eWhere each compound stands\u003c\/h3\u003e\u003cp\u003eNeither ibutamoren nor RAD-140 is a controlled drug in the UK, but uncontrolled is not the same as approved. None of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement. Free Muscle supplies them to adults aged 18 and over for laboratory research only. They are not for human consumption. MK-677 falls under WADA class S2 and RAD-140 under S1, and both are banned in sport at all times. See our \u003ca href=\"\/pages\/mk-677-legal-status-uk\"\u003eMK-677 legal status page\u003c\/a\u003e. Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e has more background on RAD-140 and its class.\u003c\/p\u003e\u003ch3\u003eWhat a sound listing shows for a two-compound pack\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eA lot number on every pack\u003c\/strong\u003e, since two products usually mean two batches.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate for each compound\u003c\/strong\u003e, each carrying the lot number of its own pack.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated strength per capsule\u003c\/strong\u003e for both compounds, and for ibutamoren whether that figure is free base or mesylate salt.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWho made it and who sells it\u003c\/strong\u003e: a named manufacturer, plus a registered UK company you can contact.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-use terms\u003c\/strong\u003e: 18+ only, no directions for use, no promised outcomes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTracked delivery in plain packaging\u003c\/strong\u003e and a stated returns policy.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eHow this bundle measures up\u003c\/h3\u003e\u003cp\u003eSeveral points are met in full. The manufacturer is named, and the seller is FreeMuscle LTD, a UK company based in Scunthorpe. Orders go by free tracked UK delivery in plain packaging, those placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3-7 working days, and unopened items can be returned within 30 days. The certificate point is batch-dependent, because a Yakka Strength COA appears only where the manufacturer has supplied one, and a bundle needs one for each compound. The strength point is not met for either. No forum review can close that gap. A fuller checklist is in \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eBoth compounds turn up as capsules, pressed tablets and so-called research liquids, which is why \"rad 140 tablets\", \"rad 140 liquid uk\" and \"mk677 uk liquid\" are all common searches. The molecule is the same in each; what differs is where measurement error enters and what degrades the material.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFormat\u003c\/th\u003e\n\u003cth\u003eHow the amount per unit is set\u003c\/th\u003e\n\u003cth\u003eMain stability concern\u003c\/th\u003e\n\u003cth\u003eWhat a certificate can report\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCapsule\u003c\/td\u003e\n\u003ctd\u003ePowder blend filled into a shell at manufacture; uniformity depends on mixing\u003c\/td\u003e\n\u003ctd\u003eHumidity softening the shell or dampening the powder\u003c\/td\u003e\n\u003ctd\u003eContent per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTablet\u003c\/td\u003e\n\u003ctd\u003ePowder compressed with binders at manufacture\u003c\/td\u003e\n\u003ctd\u003eHumidity and crumbling\u003c\/td\u003e\n\u003ctd\u003eContent per tablet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLiquid\u003c\/td\u003e\n\u003ctd\u003eConcentration of a solution, then the volume drawn\u003c\/td\u003e\n\u003ctd\u003eBreakdown in solution, precipitation, solvent loss\u003c\/td\u003e\n\u003ctd\u003eConcentration per millilitre\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eNeither compound is a peptide. Ibutamoren (528.7 g\/mol) and RAD-140 (393.8 g\/mol) are small synthetic molecules, and both were developed to work when swallowed: the ibutamoren trials gave it by mouth, and RAD-140 was described as orally bioavailable in animals before its oral phase 1 study. The digestive breakdown that undermines peptide capsules (see \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e) is therefore not the relevant question here. What matters instead is consistency: a capsule's content is fixed once, at the factory, while a liquid's depends on full dissolution and accurate measuring. None of this means any format produces an effect.\u003c\/p\u003e\u003ch2\u003eMK-677 and RAD-140 compared with their nearest relatives\u003c\/h2\u003e\u003cp\u003eFor this bundle, two comparisons dominate the searches: \"rad 140 vs rad 150\" for the SARM and \"ibutamoren vs ipamorelin\" for the secretagogue. Both are answered here on chemistry, evidence and regulation only.\u003c\/p\u003e\u003ch3\u003eRAD-140 compared with RAD-150\u003c\/h3\u003e\u003cp\u003eRAD-150, also sold as TLB-150, is not a separate development programme. PubChem records it as TLB 150 benzoate (CID 68547459, C27H20ClN5O3, 497.9 g\/mol), which is RAD-140 with a benzoate group attached as an ester. A PubMed search under RAD-150, TLB-150 and related spellings returns no study of it. Because the benzoate adds weight, only about 79 per cent of the ester by mass is the RAD-140 part, so a milligram figure on one label cannot be read across to the other. Claims that the ester lasts longer or acts more strongly have not been measured in any published work. RAD-140 is named in section S1.2 of the WADA list; RAD-150 is not named, but that section explicitly includes substances not listed by name. Brands held are on the \u003ca href=\"\/collections\/rad-150\"\u003eRAD-150 (TLB-150) collection page\u003c\/a\u003e, and the chemistry is covered in \u003ca href=\"\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eMK-677 compared with ipamorelin\u003c\/h3\u003e\u003cp\u003eIbutamoren and ipamorelin act on the same receptor, GHS-R1a, and both cause the pituitary to release growth hormone it already stores. Ibutamoren is a non-peptide small molecule; ipamorelin is a synthetic chain of five amino acids (C38H49N9O5, 711.9 g\/mol) that digestive enzymes would be expected to break down. Ibutamoren has randomised human trials measuring body composition and adverse effects, while the human literature on ipamorelin is thin, and PubMed holds no head-to-head trial of the two. Neither is licensed in the UK, and both fall within WADA section S2. Ipamorelin brands are on the \u003ca href=\"\/collections\/ipamorelin\"\u003eipamorelin collection page\u003c\/a\u003e, with a wider comparison in \u003ca href=\"\/blogs\/news\/mk-677-vs-ipamorelin-vs-hgh\"\u003eMK-677 vs ipamorelin vs HGH\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eYakka Strength is a third-party brand sold through Muscle Market. For third-party brands we display a certificate of analysis only where the manufacturer supplies one for the exact batch we hold; if none is shown, none has been supplied and we do not substitute a generic document. Free Muscle-brand products, by contrast, such as our \u003ca href=\"\/collections\/mk-677-ibutamoren\"\u003eown MK-677 capsules\u003c\/a\u003e and \u003ca href=\"\/products\/free-muscle-rad-140-testolone-10mg\"\u003eFree Muscle RAD-140 Testolone 10mg\u003c\/a\u003e, are assayed batch by batch at Janoshik Analytical, with the certificate sent on request by email. For this bundle, full documentation means two reports, one per compound. On each, look at:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity.\u003c\/strong\u003e HPLC infers identity from a peak appearing at the same retention time as a reference standard. LC-MS is firmer because it weighs the molecule: ibutamoren gives a protonated ion near m\/z 529 and RAD-140 one near m\/z 394. RAD-140 also contains a chlorine atom, so its spectrum shows a companion peak two mass units higher at roughly a third of the height; ibutamoren, with no chlorine, lacks it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity (%).\u003c\/strong\u003e The share of the detected signal belonging to the named compound. It grades the material, not the capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e The field this bundle most needs, since neither label states a strength. For ibutamoren, check whether the figure refers to free base or the heavier mesylate salt.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number.\u003c\/strong\u003e Each certificate must match the lot on its own pack; an MK-677 report says nothing about the RAD-140 capsules.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest date and laboratory.\u003c\/strong\u003e These show the result's age and its issuer.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eEach gap has a specific meaning here. A report for only one compound leaves the other unverified. Purity without a content line leaves the amount per capsule unknown. A missing or different lot number means the document belongs to another batch. \u003ca href=\"\/pages\/contact\"\u003eContact us\u003c\/a\u003e with the lot numbers and we will say exactly what exists for current stock. See our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eBoth compounds are on the WADA Prohibited List and banned at all times, in and out of competition. RAD-140 is named as an example in section S1.2, other anabolic agents. Ibutamoren sits in section S2, among the growth hormone secretagogues, a section whose substances are all non-Specified. Accredited anti-doping laboratories screen for both, and strict liability applies: an athlete answers for any prohibited substance in their sample, whatever its source, including a product bought for another purpose.\u003c\/p\u003e\u003cp\u003eNo published study gives a detection window for the capsules in this bundle, for either compound, so the accurate statement is: detectable, window not established. Controlled excretion studies would not transfer directly to capsules of unstated content in any case. The 44.7-hour half-life from the RAD-140 oncology trial describes blood levels in patients and is not a urine detection window. Anyone subject to testing should assume that any exposure to either compound could be found.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eStore the two packs separately in their original containers, lids closed between openings, in a cool, dry, dark cupboard away from radiators and steam. Moisture does the most harm: capsule shells take up water and go soft or stick together, and damp powder degrades more quickly.\u003c\/p\u003e\u003cp\u003eWe have found no published stability data for either compound in capsule form, so the expiry or best-before date printed on each pack, where there is one, marks the limit. Write the opening date next to each lot number. Never combine capsules from the two packs in a single container: only the original labels link each capsule to its compound and certificate. Treat both as laboratory reagents: gloves for opened capsules or loose powder, away from food and drink, out of reach of children and animals, any portion removed labelled with compound, lot and date, and waste disposed of as chemical waste, not in household bins or drains.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth hormone secretagogue\u003c\/strong\u003e: the class ibutamoren belongs to; such compounds prompt growth hormone release rather than supplying the hormone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHS-R1a\u003c\/strong\u003e: the ghrelin receptor, activated by both ibutamoren and ipamorelin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIGF-1\u003c\/strong\u003e: insulin-like growth factor 1, the hormone trials track as a downstream marker of raised growth hormone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator; RAD-140 is one, built without the steroid ring system of testosterone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBenzoate ester\u003c\/strong\u003e: the product of linking benzoic acid to a hydroxyl group; PubChem describes RAD-150 this way, built on RAD-140.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree base and mesylate\u003c\/strong\u003e: ibutamoren without a salt partner, and its heavier methanesulfonic acid salt.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCholestasis\u003c\/strong\u003e: a slowing or blockage of bile flow from the liver, the pattern seen in the RAD-140 case report cited here.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003em\/z\u003c\/strong\u003e: mass-to-charge ratio, the value a mass spectrometer reports for each ion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: under anti-doping codes, a positive sample is a rule violation whether or not the athlete intended to take the substance.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/mk-677\"\u003eMK-677 (Ibutamoren) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/rad-140\"\u003eRAD-140 (Testolone) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-yakka-strength\"\u003eYakka Strength brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/mk-677-ibutamoren-what-the-research-says\"\u003eMK-677 (Ibutamoren): what the research says\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eBoth compounds in this Yakka Strength bundle are supplied for laboratory research use only. Neither is a medicine or a food supplement, neither has been evaluated by the MHRA, EMA or FDA, and neither is for human consumption. Buyers must be 18 or over. Nothing here is medical or dosing advice or a recommendation to use, stack or cycle any compound; the research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eNass R, et al. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008;149(9):601-11. PMID: 18981485.\u003c\/li\u003e\n\u003cli\u003eMiller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-9. PMID: 24900290.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. PMID: 34565686.\u003c\/li\u003e\n\u003cli\u003eLeung K, et al. RAD-140 Drug-Induced Liver Injury. Ochsner J. 2022;22(4):361-365. PMID: 36561105.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Yakka Strength","offers":[{"title":"Default Title","offer_id":48468982694114,"sku":null,"price":69.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/yakka-strength-research-capsules-front-a_600x_a7c6f61a-2c4e-4759-b8fb-73a5c0dbf2fe.png?v=1789931447"},{"product_id":"yakka-strength-yakka-strength-rad140-enclomiphene-bundle","title":"Yakka Strength RAD-140 \u0026 Enclomiphene Bundle","description":"\u003cp\u003eThe Yakka Strength RAD-140 and Enclomiphene bundle lists two research compounds from one manufacturer together: testolone (RAD-140), a selective androgen receptor modulator, and enclomiphene, a selective oestrogen receptor modulator. Yakka Strength lists the pack as 60 capsules and does not state a strength per capsule, so we do not quote one. Supplied to adults for laboratory research only and not for human consumption.\u003c\/p\u003e\u003cp\u003eA bundle is a listing convenience only: it lets products from one manufacturer be ordered in a single purchase. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product. Each compound is covered on its own below.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eTestolone (RAD-140)\u003c\/h3\u003e\u003cp\u003eTestolone (RAD-140) is a non-steroidal SARM designed by Radius Health and characterised in preclinical animal models. Human data are limited to a small early oncology study. Published case reports describe drug-induced liver injury in adults who had taken products labelled RAD-140. It has never been approved as a medicine. WADA class S1. Compare brands on the \u003ca href=\"\/collections\/rad-140\"\u003eTestolone (RAD-140) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eA 2011 paper by its developers described it as potent and orally bioavailable in several preclinical models. The oncology study, published in 2022, enrolled 22 postmenopausal women with ER-positive, HER2-negative metastatic breast cancer, all heavily pretreated. The most frequent treatment-emergent adverse events were raised AST (59.1 per cent of participants), raised ALT (45.5 per cent) and raised bilirubin (27.3 per cent), with vomiting, dehydration and reduced appetite each at 27.3 per cent; 16 of the 22 had a grade 3 or 4 event. These were seriously ill, monitored patients, so the findings do not transfer to anyone else.\u003c\/p\u003e\u003ch3\u003eEnclomiphene\u003c\/h3\u003e\u003cp\u003eEnclomiphene is the trans-isomer of clomiphene, a selective oestrogen receptor modulator acting at the hypothalamus and pituitary. In a 2014 phase II trial in men with secondary hypogonadism it raised serum testosterone while sperm counts were maintained, unlike the topical testosterone comparator. It has not been approved as a medicine in the United States and it is not a licensed medicine in the UK. WADA class S4. Compare brands on the \u003ca href=\"\/collections\/enclomiphene\"\u003eEnclomiphene collection page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eBy blocking oestrogen feedback in the brain, a SERM lets more luteinising hormone (LH) and follicle-stimulating hormone (FSH) reach the testes, whereas testosterone applied from outside turns both down. In the 2014 trial LH, FSH, morning testosterone and oestradiol rose with enclomiphene. The outcomes were blood hormones and semen counts in men with a diagnosed condition, not symptoms, and the sponsor was the company developing the compound.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIdentifier\u003c\/th\u003e\n\u003cth\u003eRAD-140\u003c\/th\u003e\n\u003cth\u003eEnclomiphene\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOther names\u003c\/td\u003e\n\u003ctd\u003eTestolone, vosilasarm, EP0062\u003c\/td\u003e\n\u003ctd\u003eEnclomifene, trans-clomifene, RMI 16,289\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e1182367-47-0\u003c\/td\u003e\n\u003ctd\u003e15690-57-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular formula\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2\u003c\/td\u003e\n\u003ctd\u003eC26H28ClNO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e393.8 g\/mol\u003c\/td\u003e\n\u003ctd\u003e406.0 g\/mol (free base)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e44200882\u003c\/td\u003e\n\u003ctd\u003e1548953\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eIdentifiers are taken from PubChem. None of the research summarised above is a claim about this product.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: Yakka Strength (third-party brand, Muscle Market)\u003c\/li\u003e\n\u003cli\u003eCompounds: testolone (RAD-140) and enclomiphene\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eCOA: only where Yakka Strength supplies one for the batch held\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over, for laboratory research only\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThe listing gives one figure, 60 capsules, without a split by compound, so the pack labels are the reference. With no stated strength, milligrams per pack cannot be calculated or compared; for listings that state one, see \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eRAD-140 and enclomiphene in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"enclomiphene UK buy\", \"enclomiphene UK legal\" and \"rad 140 UK sale\" ask two things: may an adult in the UK lawfully buy these compounds, and what separates a careful listing from a careless one.\u003c\/p\u003e\u003ch3\u003eThe legal position, compound by compound\u003c\/h3\u003e\u003cp\u003eNone of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement. Neither is a controlled drug. Free Muscle supplies them to adults aged 18 and over for laboratory research only. They are not for human consumption. RAD-140 falls under WADA class S1 and enclomiphene under S4. Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e has more background.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRAD-140\u003c\/strong\u003e has never held a marketing authorisation anywhere.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnclomiphene\u003c\/strong\u003e sits in a different position because its parent, clomifene, is a prescription-only medicine in the UK. The isolated isomer was refused authorisation by the European Medicines Agency in 2018. Nothing here is an alternative to care from a doctor.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eWhat a careful UK listing shows\u003c\/h3\u003e\u003cp\u003eFor a bundle, each point applies once per compound:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eA lot number printed on each pack\u003c\/strong\u003e that the paperwork can be checked against.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA laboratory report for each compound\u003c\/strong\u003e naming that lot, dated, with identity and purity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated strength per capsule\u003c\/strong\u003e, and for enclomiphene, whether the figure refers to the citrate salt or the free base.\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eA named manufacturer and a traceable UK seller.\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-use terms\u003c\/strong\u003e: 18+, no usage instructions or promised outcomes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTracked delivery in plain packaging\u003c\/strong\u003e and a stated returns policy.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eHow this bundle measures up\u003c\/h3\u003e\u003cp\u003eThe manufacturer is named, and the seller is FreeMuscle LTD, a UK company based in Scunthorpe. Every UK order travels by free tracked delivery in plain packaging; orders placed before 2pm Monday to Friday are processed the same working day; EU delivery takes 3-7 working days; and unopened items may be returned within 30 days under our \u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e. The listing does not meet the strength point: Yakka Strength states no milligram figure, so for either compound a content figure can only come from a batch certificate, where the manufacturer has supplied one. A fuller checklist is in \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e, and delivery terms are on our \u003ca href=\"\/pages\/shipping\"\u003eshipping page\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eRAD-140 is sold as capsules, tablets and research liquids, and clomifene as tablets, hence searches for \"enclomiphene tablets\" and \"RAD 140 liquid UK\". The molecule is the same in every format; what differs is protection and measurement.\u003c\/p\u003e\u003cp\u003eA capsule holds a blend of powder and filler measured at manufacture. Unit accuracy rests on how evenly the blend was mixed, which only an assay of several capsules can confirm. Tablets share that blending step. A liquid depends on the compound fully dissolving and staying dissolved: its content is a concentration, every measured volume is only as precise as the dropper, and evaporation of the solvent slowly raises the concentration. Dry solids generally resist hydrolysis and oxidation better than solutions.\u003c\/p\u003e\u003cp\u003eNeither compound is a peptide. RAD-140 (about 394 daltons) and enclomiphene (about 406 daltons as the free base) are small synthetic molecules, so the breakdown by digestive enzymes that limits peptides taken by mouth, discussed in \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e, does not arise. The published human studies of both used oral administration. That describes study design, not any effect of these capsules. For enclomiphene there is one further point: the trials used the citrate salt, which weighs more than the free base, so a milligram figure only means something once the label or certificate says which form it counts.\u003c\/p\u003e\u003ch2\u003eRAD-140 compared with RAD-150, and enclomiphene compared with clomifene\u003c\/h2\u003e\u003cp\u003eEach compound has one dominant comparison search, \"rad 140 vs rad 150\" and \"enclomiphene vs clomiphene\", answered separately here as chemistry and regulation.\u003c\/p\u003e\u003ch3\u003eRAD-140 and RAD-150 (TLB-150)\u003c\/h3\u003e\u003cp\u003eRAD-150, sold also as TLB-150, is not a separate development programme. PubChem lists it as TLB 150 benzoate (CID 68547459), formula C27H20ClN5O3, molecular weight 497.9: the RAD-140 molecule with a benzoate ester on its hydroxyl group. A PubMed search under its market names returns no study of it; RAD-140 has the animal and Phase 1 data above.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMass\u003c\/strong\u003e: a milligram of the heavier ester carries roughly four fifths of a milligram of RAD-140, so label figures are not interchangeable.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClaims\u003c\/strong\u003e: that RAD-150 lasts longer or acts more strongly is untested, and its conversion to RAD-140 in the body is unreported.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStatus\u003c\/strong\u003e: both are unlicensed research compounds in the UK, and both fall within WADA section S1.2, which bans SARMs \"including, but not limited to\" those it names.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eRAD-150 brands held are listed in the \u003ca href=\"\/collections\/rad-150\"\u003eRAD-150 (TLB-150) collection\u003c\/a\u003e, and the chemistry is set out in \u003ca href=\"\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150 (TLB-150)\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eEnclomiphene and clomifene\u003c\/h3\u003e\u003cp\u003eClomifene (spelt clomiphene in the US) is a mixture of two geometric isomers of one molecule: enclomiphene, the (E) or trans isomer, and zuclomiphene, the (Z) or cis isomer. They share a formula but differ in shape, and zuclomiphene is cleared far more slowly. Clomifene is a prescription-only medicine in the UK, licensed for female infertility, and FDA-approved for ovulation induction. Enclomiphene alone has controlled trials in men with secondary hypogonadism but no UK, EU or US approval. WADA section S4 names clomifene among anti-oestrogenic substances, and both isomers are prohibited at all times. Our \u003ca href=\"\/blogs\/news\/enclomiphene-vs-clomifene-research-guide\"\u003eenclomiphene vs clomifene guide\u003c\/a\u003e covers the trials and adverse findings, and single-compound enclomiphene listings, including \u003ca href=\"\/products\/enclomiphene-25mg-60-capsules-free-muscle\"\u003eFree Muscle enclomiphene\u003c\/a\u003e, are in the \u003ca href=\"\/collections\/enclomiphene\"\u003eenclomiphene collection\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eYakka Strength is a third-party brand sold through Muscle Market. For third-party brands we display a certificate of analysis only where the manufacturer supplies one for the exact batch we hold; if none is shown, none has been supplied and we do not substitute a generic document. Free Muscle-brand products, by contrast, are assayed batch by batch at Janoshik Analytical, with the certificate sent on request by email. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e explains what a certificate shows.\u003c\/p\u003e\u003cp\u003eEach compound is its own batch, so a bundle needs two certificates. On either, look for:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity, RAD-140.\u003c\/strong\u003e HPLC matches the main peak to a reference standard; LC-MS is firmer, reporting the mass itself, with the protonated ion near m\/z 394.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity, enclomiphene.\u003c\/strong\u003e The right isomer matters as much as the right molecule. Enclomiphene and zuclomiphene share a mass, so an HPLC comparison with an (E)-isomer reference standard is what separates them. A certificate naming only \"clomiphene\" does not confirm enclomiphene.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e Usually an HPLC peak area percentage. For enclomiphene, zuclomiphene is the impurity of most interest. It describes the material, not the amount per capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e The line that matters most for this listing, because the label gives no strength. For enclomiphene it should say citrate or free base.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLot, date and issuing laboratory.\u003c\/strong\u003e A different lot from your pack makes the report irrelevant; a named laboratory can confirm it.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eFor this brand, a missing field means something specific. With no identity line the compound is unconfirmed; with purity but no content the strength remains unknown; with no batch number the document does not describe the pack you hold. If either compound lacks a certificate, \u003ca href=\"\/pages\/contact\"\u003econtact us\u003c\/a\u003e to ask what exists for the stock we hold. Field-by-field guidance is in \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eBoth compounds are banned in sport at all times, in and out of competition. RAD-140 is named as a SARM in section S1.2 of the WADA Prohibited List (other anabolic agents). Enclomiphene falls in section S4 (hormone and metabolic modulators), which covers anti-oestrogenic substances including SERMs and names clomifene. Strict liability applies: an athlete answers for any prohibited substance in their sample, whatever its source.\u003c\/p\u003e\u003cp\u003eThe controlled detection data concern clomifene, not isolated enclomiphene. In a 2019 open-label study at an anti-doping laboratory, 12 healthy men aged 25 to 38 took clomifene citrate for 30 days. Serum testosterone, LH and FSH rose during treatment, and zuclomiphene remained detectable in urine for between 121 and more than 261 days. Isolated enclomiphene should contain little of that long-lasting isomer, and no verified study gives its own window. For RAD-140, urine methods exist but no study cited here measures a window. For both compounds in this bundle the accurate statement is therefore: detectable, window not established.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eStore both packs unopened until needed, each in its original container with the lid closed, somewhere cool, dry and dark, away from radiators, windowsills and steamy rooms. Humidity is the main enemy of capsules: shells take up water, soften and stick, and powder that has absorbed moisture breaks down faster. Heat speeds both up, and repeated opening lets humid air in each time. Never combine the two in one pot: mixed capsules cannot be traced to a batch.\u003c\/p\u003e\u003cp\u003eWe know of no published stability study for either compound in capsule form, so any expiry or best-before date printed on the pack is the working limit. Note the opening date beside each batch number. Normal laboratory practice applies: gloves for opened capsules or loose powder, no food or drink nearby, labels on any portion removed, storage out of reach of children and pets, and disposal as chemical waste, not via bins or drains.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator; a non-steroidal class, including RAD-140, that binds testosterone's receptor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSERM\u003c\/strong\u003e: selective oestrogen receptor modulator, a compound that blocks oestrogen receptors in some tissues and activates them in others.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIsomer\u003c\/strong\u003e: one of two or more molecules with the same formula but a different arrangement of atoms; enclomiphene and zuclomiphene are geometric isomers.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCitrate salt\u003c\/strong\u003e: a compound paired with citric acid; it weighs more than the free base, which changes what a milligram figure means.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecondary hypogonadism\u003c\/strong\u003e: low testosterone caused by weak pituitary or hypothalamic signalling, not by the testes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLH and FSH\u003c\/strong\u003e: luteinising hormone and follicle-stimulating hormone, the pituitary signals that drive testosterone and sperm production.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC\u003c\/strong\u003e: a chromatography method that splits a sample into peaks; the size of the main peak gives the purity percentage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCertificate of analysis (COA)\u003c\/strong\u003e: the test report for a single production lot; a document with no lot number is a sales sheet, not a COA.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/rad-140\"\u003eRAD-140 (Testolone) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/enclomiphene\"\u003eEnclomiphene collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-yakka-strength\"\u003eYakka Strength brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/yakka-strength-yakka-strength-rad140\"\u003eYakka Strength RAD-140\u003c\/a\u003e and \u003ca href=\"\/products\/yakka-strength-yakka-strength-enclomiphene\"\u003eYakka Strength enclomiphene\u003c\/a\u003e, sold separately\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eMiller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-9. PMID: 24900290.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. PMID: 34565686.\u003c\/li\u003e\n\u003cli\u003eWiehle RD, et al. Enclomiphene citrate stimulates testosterone production while preventing oligospermia: a randomized phase II clinical trial comparing topical testosterone. Fertil Steril. 2014;102(3):720-7. PMID: 25044085.\u003c\/li\u003e\n\u003cli\u003eMiller GD, et al. Hypothalamic-Pituitary-Testicular Axis Effects and Urinary Detection Following Clomiphene Administration in Males. J Clin Endocrinol Metab. 2019;104(3):906-914. PMID: 30295816.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Yakka Strength","offers":[{"title":"Default Title","offer_id":48468982857954,"sku":null,"price":133.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/yakka-strength-research-capsule-bundle-front-z_600x_778ef193-addb-4129-9d76-ebc6de7d4618.png?v=1789931450"},{"product_id":"yakka-strength-yakka-strength-wolverine-stack-bpc157-tb500-capsule-peptide-bundle","title":"Yakka Strength Wolverine Stack — BPC-157 \u0026 TB-500","description":"\u003cp\u003eThe Yakka Strength Wolverine Stack is the manufacturer's name for a capsule bundle of two research peptides, BPC-157 (Body Protection Compound 157, also sold as BPC157) and TB-500 (TB500, a synthetic fragment of thymosin beta-4). The name is a marketing label and is not a claim about what the peptides do. Yakka Strength lists the pack as 60 capsules and does not state a peptide content per capsule, so we do not quote one. Supplied to adults for laboratory research only and not for human consumption.\u003c\/p\u003e\u003cp\u003eA bundle is a listing convenience only: it lets products from one manufacturer be ordered in a single purchase. Nothing on this page claims that they act together or should be studied together, and Free Muscle publishes no stack or cycle guidance for any product. Each peptide is therefore described on its own below.\u003c\/p\u003e\u003ch2\u003eAbout the compounds in this bundle\u003c\/h2\u003e\u003ch3\u003eBPC-157\u003c\/h3\u003e\u003cp\u003eBPC-157 is a synthetic fifteen-amino-acid peptide based on a sequence from a human gastric protein. Almost all published work is rodent and cell research, largely from one Croatian group, covering animal models of gut, tendon, muscle and vascular injury. Its developers mention early trials in inflammatory bowel disease, but no controlled human trial has been published in full, and oral absorption is unproven. WADA lists it under S0 (non-approved substances). Compare brands on the \u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eTB-500 (Thymosin Beta-4 fragment)\u003c\/h3\u003e\u003cp\u003eTB-500 is the trade name for a synthetic fragment of thymosin beta-4, a 43-amino-acid actin-binding peptide found in most human and animal cells. Reviews of thymosin beta-4 cover preclinical wound, corneal and cardiac repair models and early clinical trials of the full peptide. TB-500 itself has no published human data. When anti-doping chemists at Ghent University analysed a TB-500 product in 2012, the peptide they identified was the N-terminally acetylated 17-23 segment of thymosin beta-4, written Ac-LKKTETQ, not the whole protein. WADA names thymosin beta-4 and its derivatives, including TB-500, under S2. Compare brands on the \u003ca href=\"\/collections\/tb-500\"\u003eTB-500 (Thymosin Beta-4 fragment) collection page\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eIdentifiers\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIdentifier\u003c\/th\u003e\n\u003cth\u003eBPC-157\u003c\/th\u003e\n\u003cth\u003eThymosin beta-4 (parent of TB-500)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eLength\u003c\/td\u003e\n\u003ctd\u003e15 amino acids\u003c\/td\u003e\n\u003ctd\u003e43 amino acids; TB-500 is a 7-residue acetylated fragment\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular formula\u003c\/td\u003e\n\u003ctd\u003eC62H98N16O22\u003c\/td\u003e\n\u003ctd\u003eC212H350N56O78S\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e1419.5 g\/mol\u003c\/td\u003e\n\u003ctd\u003eabout 4,963 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e137525-51-0\u003c\/td\u003e\n\u003ctd\u003enot listed in our PubChem record\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e9941957\u003c\/td\u003e\n\u003ctd\u003e45382195\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch3\u003eWhat the published research reports\u003c\/h3\u003e\u003cp\u003eFor BPC-157, the most cited overview is a 2016 review by the originating Zagreb group, which gathers its own rodent findings on the gut, brain and blood vessels and proposes a brain-gut axis role. Its main limitation is that it reviews largely single-laboratory work. For thymosin beta-4, a 2012 review by Goldstein and colleagues describes actin binding, cell migration and repair findings in animal models and early human studies of the full-length protein applied to skin and eye. Neither review concerns this product or TB-500 as sold, and none of it is a claim about the bundle. The \u003ca href=\"\/blogs\/news\/bpc-157-what-research-shows\"\u003eBPC-157 research article\u003c\/a\u003e and the \u003ca href=\"\/blogs\/news\/tb-500-thymosin-beta-4-research-guide\"\u003eTB-500 and thymosin beta-4 research guide\u003c\/a\u003e go further.\u003c\/p\u003e\u003cp\u003eBoth peptides are supplied here in capsule form. Whether peptides survive the digestive tract in any meaningful quantity is an open question, discussed in our article \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides actually work?\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eBrand: Yakka Strength (third-party brand, \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e)\u003c\/li\u003e\n\u003cli\u003eCompounds: BPC-157 and TB-500 (thymosin beta-4 fragment)\u003c\/li\u003e\n\u003cli\u003eForm and pack size: 60 capsules, as listed by the manufacturer\u003c\/li\u003e\n\u003cli\u003ePeptide content per capsule: not stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eTotal milligrams per pack: cannot be worked out without a stated strength\u003c\/li\u003e\n\u003cli\u003eCOA: only where Yakka Strength supplies one for the batch held\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over, for laboratory research only\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThe two peptides are also listed singly as \u003ca href=\"\/products\/yakka-strength-yakka-strength-bpc157-peptide-capsules\"\u003eYakka Strength BPC-157 capsules\u003c\/a\u003e and \u003ca href=\"\/products\/yakka-strength-yakka-strength-tb500-peptide-capsules\"\u003eYakka Strength TB-500 capsules\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eBPC-157 and TB-500 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"BPC157 TB500 UK\", \"buy TB 500 UK\" and \"TB 500 legal UK\" come down to three questions: is it lawful to sell, who is a credible supplier, and what the listing should prove.\u003c\/p\u003e\u003ch3\u003eLegal position\u003c\/h3\u003e\u003cp\u003eNone of the compounds on this page is a licensed medicine in the United Kingdom, none has been assessed by the MHRA and none is an authorised food supplement. Neither peptide is a controlled drug. They are supplied only as research materials, never for human consumption. Free Muscle supplies them to adults aged 18 and over for laboratory research only. There is no licensed product containing either peptide, so neither is available on prescription. BPC-157 is listed by WADA under S0 and TB-500 under S2, and both are prohibited at all times in tested sport. Buyers are responsible for the rules that apply to them. Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e has more background.\u003c\/p\u003e\u003ch3\u003eWhat a trustworthy UK listing shows\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBoth compounds named separately\u003c\/strong\u003e, with the manufacturer identified, rather than a blend described only by a nickname.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA lot or batch number\u003c\/strong\u003e on each container, because test results attach to batches, not to product names.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for that batch\u003c\/strong\u003e, covering each peptide in the bundle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated strength\u003c\/strong\u003e per capsule for each peptide, or an honest note that none is given.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSale terms that match the law\u003c\/strong\u003e: adults only, laboratory use stated, and no usage instructions or promised effects.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA traceable UK seller\u003c\/strong\u003e with tracked delivery, plain packaging and a written returns policy.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eHow this listing measures up\u003c\/h3\u003e\u003cp\u003eFreeMuscle LTD is a UK company based in Scunthorpe. The manufacturer is named, sales are restricted to adults and this page gives no directions for use. Every order ships by free tracked UK delivery in plain packaging, orders placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3 to 7 working days, and unopened items can be returned within 30 days. Two points depend on Yakka Strength: the label gives no per-capsule strength, so that check is not met, and a certificate appears only where one has been supplied for the batch we hold. Our \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e sets out these checks in full, and delivery terms are on the \u003ca href=\"\/pages\/shipping\"\u003eshipping page\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eBPC-157 and TB-500 are both offered as capsules or tablets, as freeze-dried powder in sealed vials, and occasionally as pre-mixed liquids. The research literature on both peptides relies overwhelmingly on injection: into the abdominal cavity or muscle in rodent studies of BPC-157, and by injection or topical application in thymosin beta-4 work. Some Zagreb experiments gave BPC-157 in drinking water, but no study has measured blood levels in people after an oral dose of either peptide.\u003c\/p\u003e\u003cp\u003eThe obstacle for any swallowed peptide is enzymatic. Pepsin in the stomach and trypsin, chymotrypsin and brush-border peptidases in the small intestine cleave peptide bonds, and short linear chains such as a 15-residue or 7-residue peptide are ordinary substrates. The originating group reports that BPC-157 resists human gastric juice in its own tests; no equivalent claim has been published for the TB-500 fragment. Whether either survives in meaningful amounts is unresolved, which is the subject of \u003ca href=\"\/blogs\/news\/bpc-157-capsules-vs-injection-what-studies-used\"\u003eBPC-157 capsules vs injection: what the studies used\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eAs materials, the formats behave differently. Dry powder, in a capsule or sealed vial, is more stable than peptide in solution. Fill accuracy is another difference: a capsule's content depends on how evenly the powder was blended with filler before encapsulation, while a liquid's depends on how accurately it was made up and measured. None of this implies that any format produces an effect.\u003c\/p\u003e\u003ch2\u003eBPC-157 compared with TB-500\u003c\/h2\u003e\u003cp\u003e\"TB 500 vs BPC 157\" is the comparison searched most often for this pair. Though often sold side by side, they are unrelated, with different parent proteins, different research traditions and different anti-doping classifications.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrigin.\u003c\/strong\u003e BPC-157 is a 15-residue sequence (GEPPPGKPADDAGLV) derived from a protein in gastric juice. TB-500 is built around residues 17 to 23 of thymosin beta-4, the segment linked to actin binding.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProposed mechanism.\u003c\/strong\u003e Work on BPC-157 points to growth factor, nitric oxide and cell-signalling pathways in rodent tissue. Thymosin beta-4 is best known for holding a pool of unpolymerised actin, which influences how cells migrate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvidence base.\u003c\/strong\u003e BPC-157 has rodent and cell studies, mostly from one research network, and no published randomised human trial. Thymosin beta-4 has animal studies from many laboratories and small early human trials of the full protein; the TB-500 fragment itself has none.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegulatory status.\u003c\/strong\u003e Both are unlicensed research compounds in the UK, with no approval from the MHRA, EMA or FDA.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWADA class.\u003c\/strong\u003e S0 for BPC-157, as a substance with no therapeutic approval; S2 for TB-500, because the list names thymosin beta-4 and its derivatives.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eIs TB-500 the same as thymosin beta-4?\u003c\/h3\u003e\u003cp\u003eNo, although the names are often used interchangeably. Thymosin beta-4 is the whole 43-residue protein, about 4,963 g\/mol. The product sold as TB-500 was shown by laboratory analysis to contain the acetylated seven-residue fragment Ac-LKKTETQ, a far smaller molecule. No human study has compared BPC-157 with TB-500, so neither can be ranked above the other, and we give no guidance on studying them together. Single-compound listings are on the \u003ca href=\"\/collections\/tb-500\"\u003eTB-500 collection\u003c\/a\u003e and \u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection\u003c\/a\u003e pages, and the wider class is covered in \u003ca href=\"\/blogs\/news\/sarms-vs-peptides-choosing-by-goal\"\u003eSARMs vs peptides\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eYakka Strength is a third-party brand sold through Muscle Market. For third-party brands we display a certificate of analysis only where the manufacturer supplies one for the exact batch we hold; if none is shown, none has been supplied and we do not substitute a generic document. Free Muscle-brand products, by contrast, are assayed batch by batch at Janoshik Analytical, with the certificate sent on request by email, as with our own \u003ca href=\"\/collections\/bpc-150\"\u003eBPC-150 capsules\u003c\/a\u003e. That testing does not extend to Yakka Strength.\u003c\/p\u003e\u003cp\u003eA certificate covering one peptide says nothing about the other, so read each line against the pack:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound named.\u003c\/strong\u003e The report should say whether it covers BPC-157, TB-500 or both, and which container it belongs to.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity method.\u003c\/strong\u003e HPLC compares retention time with a reference standard; LC-MS also measures molecular mass. For TB-500, the mass found should match the small acetylated fragment, not the full thymosin beta-4 protein, which is one of the clearest identity checks available.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity percentage.\u003c\/strong\u003e How much of the detected material is the named peptide rather than synthesis by-products; a high figure says nothing about the quantity in a capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e The only figure that could supply the strength missing from this label. It should say whether it reports net peptide or total powder.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number and test date.\u003c\/strong\u003e These must match the lot printed on the container and show how recent the analysis is.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory name.\u003c\/strong\u003e An unnamed lab cannot be asked to confirm that it issued the report.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eFor this brand, a missing field matters directly: with no content line the strength stays unknown, and a report without a batch number cannot be linked to the capsules in hand. To ask what exists for current stock, send the batch number on the pack through our \u003ca href=\"\/pages\/contact\"\u003econtact page\u003c\/a\u003e. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab testing page\u003c\/a\u003e explains what a certificate shows, and \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e works through an example.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eBoth peptides are prohibited at all times, in and out of competition, under the World Anti-Doping Code, which UK Anti-Doping applies in the UK. BPC-157 is named in S0, the class for substances with no current approval for human therapeutic use. TB-500 falls under S2 through thymosin beta-4 and its derivatives. Strict liability applies, so an athlete is responsible for whatever is found in a sample, whatever the label said.\u003c\/p\u003e\u003cp\u003eAnti-doping laboratories have published methods for each. In 2012 the Ghent doping control laboratory identified Ac-LKKTETQ in a TB-500 product by high-resolution mass spectrometry, synthesised a reference standard and proposed a strategy for finding it in plasma and urine. In 2017 the Salt Lake City laboratory validated a urine test for BPC-157 with a limit of detection of 0.1 ng\/mL, found the peptide stable in urine for at least four days, and improved specificity by measuring a stable metabolite as well. Neither study established how long either peptide stays detectable after human exposure, so the accurate position for both is detectable, window not established.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eNo published stability study covers BPC-157 or TB-500 in capsule form, so the expiry or best-before date printed by the manufacturer, if there is one, is the limit to observe. General peptide chemistry indicates the main risks. Water drives hydrolysis of peptide bonds and makes powder clump and gelatin shells soften. Heat speeds up degradation and some amino acids oxidise over time, a process that light can accelerate.\u003c\/p\u003e\u003cp\u003eKeep each container tightly closed in a cool, dry, dark cupboard, away from heaters and steamy rooms, with any desiccant left in place. If a container is refrigerated, allow it to reach room temperature before opening so moisture does not condense inside. Keep capsules in the original container that carries the batch number, so they can still be matched to a certificate. Handle the contents as laboratory reagents: gloves when working with opened capsules, separation from food and drink, storage out of reach of children and pets, and disposal as chemical waste rather than down a drain.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eActin\u003c\/strong\u003e: a structural protein inside cells; thymosin beta-4 binds its unpolymerised form.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcetylation\u003c\/strong\u003e: addition of an acetyl group, here to the start of the TB-500 fragment, marked \"Ac-\" in its sequence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtease\u003c\/strong\u003e: an enzyme that cuts peptide bonds, found throughout the digestive tract.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetention time\u003c\/strong\u003e: how long a compound takes to pass through a chromatography column, used to match it to a standard.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh-resolution mass spectrometry\u003c\/strong\u003e: measurement of molecular mass precise enough to separate compounds of very similar weight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eS0 and S2\u003c\/strong\u003e: WADA Prohibited List sections for non-approved substances and for hormones, growth factors and related substances.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: the anti-doping rule that an athlete answers for any prohibited substance in a sample.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/bpc-157\"\u003eBPC-157 collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/tb-500\"\u003eTB-500 (Thymosin Beta-4) collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-yakka-strength\"\u003eYakka Strength brand page\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/peptides\"\u003ePeptides collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/market-bundles\"\u003eBundles collection\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eSupplied for laboratory research use only. Not a medicine, not evaluated by the MHRA, EMA or FDA, and not for human consumption. Buyers must be 18 or over. Nothing on this page is medical or dosing advice or a recommendation to use, stack or cycle any compound; research summaries describe findings in study participants or animals, not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eSikiric P, et al. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Curr Neuropharmacol. 2016;14(8):857-865. PMID: 27138887.\u003c\/li\u003e\n\u003cli\u003eGoldstein AL, et al. Thymosin beta4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther. 2012;12(1):37-51. PMID: 22074294.\u003c\/li\u003e\n\u003cli\u003eEsposito S, et al. Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential. Drug Test Anal. 2012;4(9):733-8. PMID: 22962027.\u003c\/li\u003e\n\u003cli\u003eCox HD, et al. Detection and in vitro metabolism of the confiscated peptides BPC 157 and MGF R23H. Drug Test Anal. 2017;9(10):1490-1498. PMID: 28035768.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Yakka Strength","offers":[{"title":"Default Title","offer_id":48468983021794,"sku":null,"price":101.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/yakka-strength-research-capsules-bundle-front-d_600x_98cd7685-3b1a-48c2-983e-e465ef78b74a.png?v=1789931453"}],"url":"https:\/\/freemuscle.co.uk\/collections\/market-bundles.oembed","provider":"Free Muscle","version":"1.0","type":"link"}