{"title":"RAD-140 (Testolone)","description":"\u003cp\u003eRAD-140, also known as testolone and by its development code RAD140, is a non-steroidal selective androgen receptor modulator (SARM) first described by Radius Health in 2011. It is a small oral molecule that binds the androgen receptor with high affinity and was designed to act preferentially in muscle and bone rather than in the prostate. This page lists every brand of RAD-140 stocked at Free Muscle, compared on strength per capsule, capsules per pack and batch testing, and summarises what the published research does and does not show.\u003c\/p\u003e\n\u003ch2\u003eWhat is RAD-140?\u003c\/h2\u003e\n\u003cp\u003eRAD-140 belongs to the SARM class: synthetic, non-steroidal ligands of the androgen receptor (AR), the same nuclear receptor that testosterone and dihydrotestosterone act on. The premise of the class is tissue selectivity: strong receptor activation in skeletal muscle and bone, much weaker agonism in the prostate, seminal vesicles and skin. RAD-140 was reported by its discoverers to be a potent, orally bioavailable AR ligand that showed this pattern in animal models.\u003c\/p\u003e\n\u003cp\u003eRadius Health originally explored RAD-140 as a treatment for muscle wasting and, later, as an oral AR-targeted agent for androgen receptor positive breast cancer. The only human data in the literature come from that oncology programme, a small first-in-human phase 1 study in postmenopausal women with metastatic breast cancer. There are no published controlled trials of RAD-140 in healthy adults, and no data at all on the long-term effects of the compound in people.\u003c\/p\u003e\n\u003cp\u003eRAD-140 has never been approved as a medicine anywhere in the world. Its clinical development did not proceed beyond early phase, and it holds no marketing authorisation from the MHRA, EMA or FDA.\u003c\/p\u003e\n\u003ch2\u003eWhat the published research reports\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDiscovery and preclinical characterisation (2011).\u003c\/strong\u003e Miller and colleagues at Radius Health described the design and synthesis of RAD140 and its characterisation in several preclinical models of anabolic androgen action, reporting it as a potent, orally bioavailable, non-steroidal SARM. This is a chemistry and animal-model paper; it contains no human data.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNeuroprotection in rat models (2014).\u003c\/strong\u003e Jayaraman and colleagues tested RAD140 in cultured rat hippocampal neurons and in male rats given the excitotoxin kainate. In culture, RAD140 was as effective as testosterone at reducing apoptotic cell death, an effect that depended on MAPK signalling. In gonadectomised adult rats it exhibited peripheral androgen action that largely spared the prostate while protecting hippocampal neurons.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFirst-in-human phase 1 study (2022).\u003c\/strong\u003e LoRusso and colleagues enrolled 22 heavily pretreated postmenopausal women with ER-positive, HER2-negative metastatic breast cancer in a dose-escalation study. The most frequent treatment-emergent adverse events were elevated AST (59.1 per cent of patients), elevated ALT (45.5 per cent), raised total bilirubin (27.3 per cent), vomiting, dehydration and decreased appetite and weight. Grade 3 or 4 adverse events occurred in 72.7 per cent of patients, including AST and ALT elevations and hypophosphataemia. Clinical benefit rate at 24 weeks was 18.2 per cent and median progression-free survival was 2.3 months.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLiver injury case report (2020).\u003c\/strong\u003e Barbara and colleagues described a 52-year-old man who developed drug-induced liver injury after taking online products containing RAD-140 and RAD-140 with LGD-4033. Liver biopsy showed diffuse centrilobular canalicular cholestasis with ductular reaction and mild lobular inflammation. Liver enzymes returned to normal roughly three months after both products were stopped.\u003c\/p\u003e\n\u003cp\u003eThese findings describe study participants, patients and laboratory animals. None of them is a claim about the products listed on this page.\u003c\/p\u003e\n\u003ch2\u003eBrands of RAD-140 we stock\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree Muscle RAD-140 Testolone, 10mg, 60 capsules.\u003c\/strong\u003e Our own brand. Every batch is assayed by Janoshik Analytical and the batch certificate is available by email on request. \u003ca href=\"\/products\/free-muscle-rad-140-testolone-10mg\"\u003eView the Free Muscle RAD-140 listing\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eiMuscle Testolone RAD-140, 10mg, 60 capsules.\u003c\/strong\u003e Capsule form. A COA is shown on the listing only where iMuscle has supplied one for the batch we hold. \u003ca href=\"\/products\/imuscle-testolon-rad-140-60-10mg\"\u003eView the iMuscle RAD-140 listing\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eYakka Strength RAD-140, 60 capsules.\u003c\/strong\u003e Capsule form; strength per capsule is as stated on the manufacturer's label, so check the listing. COA shown where the manufacturer provides one for the batch. \u003ca href=\"\/products\/yakka-strength-yakka-strength-rad140\"\u003eView the Yakka Strength RAD-140 listing\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThoroughbred Labs RAD-140, 60 capsules.\u003c\/strong\u003e Capsule form; strength as labelled by the manufacturer. COA shown where supplied for the batch held. \u003ca href=\"\/products\/thoroughbred-labs-rad140\"\u003eView the Thoroughbred Labs RAD-140 listing\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree Muscle Research Bundle (MK-677, RAD-140 and YK-11).\u003c\/strong\u003e Three Free Muscle-brand compounds sold together for laboratory work, each from a Janoshik-assayed batch. \u003ca href=\"\/products\/christmas-bulking-bundle\"\u003eView the research bundle\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHow to compare them\u003c\/h3\u003e\n\u003cp\u003eStart with total milligrams per pack: strength per capsule multiplied by capsules per pack. Two 60-capsule packs at 10mg each contain 600mg, so any difference between them is in price, provenance and testing rather than quantity. Divide the pack price by total milligrams to get cost per milligram, the only figure that compares packs of different strengths fairly. Then look at the batch certificate. A pack with an independently issued COA for its lot number is a known quantity; a pack without one is not, whatever the label says. Our article on \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e walks through the arithmetic.\u003c\/p\u003e\n\u003ch2\u003eBatch testing and certificates of analysis\u003c\/h2\u003e\n\u003cp\u003eA certificate of analysis (COA) answers the two questions that matter about a RAD-140 capsule: is the compound what the label says, and how much is present. A genuine batch certificate is issued by an independent laboratory, names the lot number, and reports identity (by HPLC or mass spectrometry against a reference standard) and assayed purity or content.\u003c\/p\u003e\n\u003cp\u003eEvery Free Muscle-brand batch is assayed by Janoshik Analytical, an independent laboratory, and the certificate for the batch you receive is sent on request by email. For other brands we show a COA only where the manufacturer has supplied one for the batch we hold. A generic PDF with no batch number, or one dated long before the product was made, is not a batch certificate and tells you nothing about the capsules in your hand. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab tests page\u003c\/a\u003e explains how to read a Janoshik certificate and match it to your batch.\u003c\/p\u003e\n\u003ch2\u003eLegal status in the UK\u003c\/h2\u003e\n\u003cp\u003eRAD-140 is not a licensed medicine in the United Kingdom. It has never been granted a marketing authorisation by the MHRA, and it is not an authorised food supplement or a permitted novel food ingredient. It cannot legally be sold or labelled for human consumption. Free Muscle sells RAD-140 to adults aged 18 or over for laboratory and research purposes only, and every listing states this. RAD-140 is named on the World Anti-Doping Agency Prohibited List under S1.2, Other Anabolic Agents, and is prohibited at all times. Anyone subject to anti-doping rules should treat any product in this class as prohibited at all times, in and out of competition. For a fuller overview of the class, see our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eresearch guide to SARMs\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eStorage and handling\u003c\/h2\u003e\n\u003cp\u003eKeep RAD-140 capsules in the original sealed container in a cool, dry place away from light and heat. Do not decant into unlabelled containers, and record the batch number so that a COA request can be matched to the exact material. Keep out of reach of children and pets, and follow standard laboratory good practice: gloves when handling, no eating or drinking in the work area, and disposal in line with local rules for research chemicals.\u003c\/p\u003e\n\u003ch2\u003eDelivery and returns\u003c\/h2\u003e\n\u003cp\u003eFree Muscle is a UK company (FreeMuscle LTD, Scunthorpe). Every order ships with free tracked UK delivery in plain packaging. Orders placed before 2pm Monday to Friday are processed the same working day. EU delivery takes 3 to 7 working days. Unopened items can be returned within 30 days. Customers must be 18 or over. Full details are on our \u003ca href=\"\/pages\/shipping\"\u003eshipping page\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eguarantee page\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eRelated reading\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/sarms-explained-how-selective-androgen-receptor-modulators-work-1135-86\"\u003eSARMs explained: how selective androgen receptor modulators work\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003eHow to read a certificate of analysis\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/what-is-janoshik-analytical\"\u003eWhat is Janoshik Analytical?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/muscle-market-launch\"\u003eMuscle Market: five brands, one basket, one parcel\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eRelated collections: \u003ca href=\"\/collections\/rad-150\"\u003eRAD-150 (TLB-150)\u003c\/a\u003e, \u003ca href=\"\/collections\/lgd-4033\"\u003eLGD-4033 (Ligandrol)\u003c\/a\u003e, \u003ca href=\"\/collections\/yk-11\"\u003eYK-11\u003c\/a\u003e, \u003ca href=\"\/collections\/sarms\"\u003eall SARMs\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eRAD-140 is sold strictly for laboratory research use only. It is not a licensed medicine, has not been evaluated or approved by the MHRA, EMA or FDA, is not a food supplement and is not for human consumption. Buyers must be 18 or over. Nothing on this page is medical advice, dosing advice or a recommendation to use this compound in any way; the published findings summarised above describe study participants and laboratory models, not the products listed.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"free-muscle-rad-140-testolone-10mg","title":"RAD-140 Testolone — 10mg · 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eRAD-140 (Testolone) — 10mg × 60 capsules.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eRAD-140 is a selective androgen receptor modulator. It binds androgen receptors with more selectivity for muscle and bone tissue than anabolic steroids do. Preclinical data exists; human efficacy trials for performance do not.\u003c\/p\u003e\u003cp\u003eSARMs have been associated with liver injury and testosterone suppression in published case reports. RAD-140 is \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e and is on the WADA Prohibited List, where it is detectable in standard screening.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request. We do not publish dosing schedules, cycle lengths or post-cycle protocols for human use.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Not a medicine or dietary supplement, not evaluated by the MHRA, EMA or FDA, not for human consumption.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":46857401336034,"sku":"10000015","price":49.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/openart-image_5GqoU6sK_1760820649070_raw_2e570237-2351-490e-a6a5-64bdfb2fd16d.jpg?v=1766262381"},{"product_id":"imuscle-testolon-rad-140-60-10mg","title":"iMuscle Testolone RAD-140 — 60 caps, 10mg","description":"\u003cp\u003eiMuscle Testolone RAD-140 comes as 60 capsules stated at 10 mg each, giving 600 mg of RAD-140 per pack. RAD-140, or testolone, is a non-steroidal selective androgen receptor modulator with a single published clinical trial. iMuscle manufactures the product; Free Muscle stocks it in the Muscle Market range and ships it from the UK to adults for laboratory research only.\u003c\/p\u003e\u003ch2\u003eAbout RAD-140\u003c\/h2\u003e\u003cp\u003eRAD-140 is a synthetic, non-steroidal selective androgen receptor modulator, commonly called testolone. Like other SARMs it binds the androgen receptor, but it has no steroid ring system and its structure is unrelated to testosterone. Radius Health described its discovery in 2011 as a potent, orally bioavailable SARM and reported its characterisation in several preclinical animal models of anabolic androgen action (Miller et al., 2011).\u003c\/p\u003e\u003cp\u003eRAD-140 later entered a Phase 1 oncology trial in women with ER-positive, HER2-negative advanced breast cancer, published in 2022 (LoRusso et al., 2022). Twenty-two heavily pretreated patients took part. The adverse events recorded most often were raised AST (59%), ALT (45%) and bilirubin (27%), and grade 3 or 4 events occurred in 16 of the 22. Outside clinical research, published case reports link RAD-140 to cholestatic liver injury, including a biopsy-supported case in a 24-year-old man that resolved after exposure stopped (Leung et al., 2022).\u003c\/p\u003e\u003cp\u003eThe only other structured human data come from anti-doping research: a 2022 Cologne study gave adult male volunteers microgram amounts to chart how RAD-140 is excreted, covered under detection below (Wagener et al., 2022). No published trial has measured muscle, strength or body composition in healthy adults. The research described here relates to the molecule in laboratory and clinical settings and is not a claim about this listing.\u003c\/p\u003e\u003ch3\u003eChemical identity\u003c\/h3\u003e\u003cp\u003eIdentifiers from PubChem, against which a laboratory result can be checked:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystematic name\u003c\/strong\u003e: 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number\u003c\/strong\u003e: 1182367-47-0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormula and molecular weight\u003c\/strong\u003e: C20H16ClN5O2, 393.8 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInChIKey\u003c\/strong\u003e: XMBUPPIEVAFYHO-KPZWWZAWSA-N\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePubChem CID\u003c\/strong\u003e: 44200882\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOther names\u003c\/strong\u003e: testolone, vosilasarm, EP0062\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCompound: RAD-140 (Testolone)\u003c\/li\u003e\n\u003cli\u003eBrand: iMuscle\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStated strength: 10 mg per capsule (manufacturer's label claim)\u003c\/li\u003e\n\u003cli\u003eStated total per pack: 600 mg\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThe strength is the manufacturer's label claim; only a batch certificate confirms it. To compare brands of RAD-140, use total milligrams per pack, as explained in \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e. Of the RAD-140 listings we stock, only this one and the Free Muscle-brand pack state a per-capsule strength; the Yakka Strength and Thoroughbred Labs listings do not.\u003c\/p\u003e\u003ch2\u003eRAD-140 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eUK searches such as \"RAD140 for sale UK\" and \"testolone RAD 140 UK\" raise two practical questions: what the law allows, and what evidence a listing should offer.\u003c\/p\u003e\u003ch3\u003eLegal status\u003c\/h3\u003e\u003cp\u003eNo UK medicines licence exists for RAD-140: the MHRA has never granted it a marketing authorisation, and no regulator elsewhere has licensed it either. Nor is it an authorised food supplement, so selling it for human consumption would be unlawful. It is not a controlled drug. Free Muscle supplies it only as a research compound, to adults aged 18 or over, for laboratory use. WADA prohibits it at all times under section S1 (anabolic agents) of its Prohibited List. Buyers are responsible for the rules that apply to them, including any anti-doping code. Background on the class is in \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eWhy a label proves little on its own\u003c\/h3\u003e\u003cp\u003eThe case for checking is empirical. A US anti-doping laboratory, working with the US Anti-Doping Agency, bought 44 products sold online as SARMs and analysed them: in 26 the amount of active compound differed substantially from the label, and 17 contained a different unapproved drug altogether, among them ibutamoren, GW501516 and SR9009 (Van Wagoner et al., 2017). It concerned US websites in 2016, not this product.\u003c\/p\u003e\u003ch3\u003eQuestions to ask of any listing, answered for this one\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eQuestion\u003c\/th\u003e\n\u003cth\u003eThis iMuscle listing\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eIs a strength printed, with a capsule count?\u003c\/td\u003e\n\u003ctd\u003eYes: 10 mg per capsule, 60 capsules, 600 mg per pack (manufacturer's claim)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWho makes it?\u003c\/td\u003e\n\u003ctd\u003eiMuscle\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWho sells it, and from where?\u003c\/td\u003e\n\u003ctd\u003eFreeMuscle LTD, a UK company based in Scunthorpe\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIs there a certificate for the batch sold?\u003c\/td\u003e\n\u003ctd\u003eShown only where iMuscle supplies one for the batch we hold\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAre the terms research-only?\u003c\/td\u003e\n\u003ctd\u003eYes: laboratory research, adults 18+, no directions for use and no promised outcomes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHow does it travel?\u003c\/td\u003e\n\u003ctd\u003eFree tracked delivery on every UK order, in plain packaging; same-day processing for orders before 2pm Monday to Friday; 3-7 working days to the EU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCan it be returned?\u003c\/td\u003e\n\u003ctd\u003eUnopened items, within 30 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eOnly the certificate depends on the manufacturer. Personal accounts under \"RAD 140 UK reddit\" or \"best RAD 140 UK\" describe experiences, not the contents of a pack; only a batch certificate measures those. More checks are in \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eiMuscle is a third-party brand, so any certificate of analysis (COA) for this product is the manufacturer's, not ours. A COA is shown only where iMuscle supplies one for the batch we hold; a generic document is not a substitute for a batch certificate. Free Muscle-brand compounds are assayed batch by batch at Janoshik Analytical; that programme does not cover iMuscle. A genuine batch certificate names its method, HPLC or LC-MS; check an iMuscle certificate in this order:\u003c\/p\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound named.\u003c\/strong\u003e It should say RAD-140, or a synonym such as testolone or vosilasarm. A certificate for RAD-150, or for an unnamed \"SARM\", is not a certificate for this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity result.\u003c\/strong\u003e A chromatogram alone shows that something eluted where a RAD-140 reference standard does; a mass spectrum shows a molecule of the right mass, for protonated RAD-140 an ion at m\/z 394.1065 (Wagener et al., 2022).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e A share of chromatogram peak area. It describes how clean the material is; a capsule could meet a high purity figure and still hold far more or far less than 10 mg.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e The measured figure to set against the 10 mg claim; sixty times it is the real pack total. One assay gives the average of the capsules tested, not the spread between them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLot number, test date and laboratory.\u003c\/strong\u003e The lot must match your pack; the date shows how old the result is.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003ePurity without a content figure leaves the 10 mg claim, and with it the 600 mg total, unconfirmed. A result with no stated method cannot be weighed. A lot number that is missing, or differs from the one on your pot, means the certificate concerns another production run. In any of those cases, \u003ca href=\"\/pages\/contact\"\u003eask us\u003c\/a\u003e before relying on the batch. See also \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e and our \u003ca href=\"\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eTestolone tablets and RAD-140 \"research liquids\" are also on the market, and searches such as \"RAD 140 tablets\" and \"RAD 140 liquid UK\" reflect that. Whatever the format, the molecule is RAD-140; what varies is how reliably the printed amount reaches each unit, and no one has published a comparison for this compound.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eWhat the label figure relies on\u003c\/th\u003e\n\u003cth\u003eWhat its certificate should state\u003c\/th\u003e\n\u003cth\u003eStorage sensitivity\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCapsule (this product)\u003c\/td\u003e\n\u003ctd\u003eUniform mixing of the powder and a consistent fill in every shell\u003c\/td\u003e\n\u003ctd\u003eMilligrams per capsule, to set against 10 mg\u003c\/td\u003e\n\u003ctd\u003eMoisture: shells soften and the powder clumps\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTablet\u003c\/td\u003e\n\u003ctd\u003eUniform mixing, then pressing with binders and sometimes a coating\u003c\/td\u003e\n\u003ctd\u003eMilligrams per tablet\u003c\/td\u003e\n\u003ctd\u003eMoisture and breakage\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLiquid\u003c\/td\u003e\n\u003ctd\u003eComplete dissolution, a solution that stays stable, and accurate measuring of every volume drawn\u003c\/td\u003e\n\u003ctd\u003eMilligrams per millilitre, on the test date\u003c\/td\u003e\n\u003ctd\u003eChemical change in solution; evaporation concentrates what remains\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eBecause RAD-140 is a small molecule rather than a peptide, the question that dominates debate over swallowed peptides, whether digestive enzymes break them down, does not arise in the same way (see \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e). Both human studies gave it by mouth; we know of no published study of RAD-140 by injection.\u003c\/p\u003e\u003ch2\u003eRAD-140 compared with RAD-150 (TLB-150)\u003c\/h2\u003e\u003cp\u003e\"RAD 140 vs RAD 150\", also searched as \"TLB 150 vs RAD 140\", is the comparison most often made for this compound.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eRAD-140 (this product)\u003c\/th\u003e\n\u003cth\u003eRAD-150 (TLB-150)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eRelationship\u003c\/td\u003e\n\u003ctd\u003eParent molecule\u003c\/td\u003e\n\u003ctd\u003eBenzoate ester of RAD-140, recorded in PubChem as \"TLB 150 Benzoate\" (CID 68547459)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and molecular weight\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2, 393.8\u003c\/td\u003e\n\u003ctd\u003eC27H20ClN5O3, 497.9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWhere it appears in print\u003c\/td\u003e\n\u003ctd\u003ePeer-reviewed journals since 2011\u003c\/td\u003e\n\u003ctd\u003eA patent, US 8,629,167 (compound 87); no journal papers\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIC50 for androgen receptor binding, patent assay\u003c\/td\u003e\n\u003ctd\u003e2 nM\u003c\/td\u003e\n\u003ctd\u003e130 nM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStudies in people\u003c\/td\u003e\n\u003ctd\u003eOne cancer trial and one anti-doping excretion study\u003c\/td\u003e\n\u003ctd\u003eNo published study\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA Prohibited List\u003c\/td\u003e\n\u003ctd\u003eListed by name in S1.2\u003c\/td\u003e\n\u003ctd\u003eAbsent from the examples; covered by the section's open wording\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThe binding figures come from the patent, as deposited in PubChem, not from a journal, and describe the intact molecules in a commercial binding kit. On them the ester bound the receptor about 65 times more weakly than RAD-140. A living system may split an ester back to its parent, so this does not settle what RAD-150 does there, but it argues against the ester being a stronger ligand in its own right. Claims that it lasts longer or acts more strongly are unmeasured, and whether, and how fast, it becomes RAD-140 in the body is unknown.\u003c\/p\u003e\u003cp\u003eThe heavier formula matters for labels too: roughly a fifth of the ester's mass comes from the added benzoate portion, so a milligram figure for RAD-150 and the 600 mg on this pack do not describe the same quantity of the RAD-140 structure. Legally the two are alike: neither is a licensed medicine or an authorised food, and both are sold here for laboratory research only. WADA names RAD140 in S1.2; RAD-150 is absent, but the section introduces its examples with \"including, but not limited to\", so absence is no exemption. Brands held are in the \u003ca href=\"\/collections\/rad-150\"\u003eRAD-150 (TLB-150) collection\u003c\/a\u003e; the chemistry is set out in \u003ca href=\"\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150 (TLB-150)\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eRAD-140 is named, as RAD140, under S1.2 (other anabolic agents) of the WADA Prohibited List, banned at all times. Under strict liability an adverse analytical finding stands against the athlete whatever its source, be it a research compound, a mislabelled product or a contaminated supplement.\u003c\/p\u003e\u003cp\u003eIts persistence in urine has been measured, though only after very small amounts. At the German Sport University Cologne, six excretion studies, each with five adult male volunteers, used single or five daily amounts of 1, 10 or 50 micrograms, and their urine was analysed by LC-HRMS\/MS (Wagener et al., 2022). Unchanged RAD-140 outlasted all six metabolites tracked in every group. After one 50 microgram amount it was found up to 696 hours later, about 29 days; after five daily amounts of 50 micrograms, up to 912 hours, about 38 days, after the last. Part of the aim was to help laboratories judge whether a finding reflects deliberate use or contamination.\u003c\/p\u003e\u003cp\u003eEvery figure above comes from microgram exposures. How long RAD-140 remains detectable after milligram quantities, such as the 10 mg stated per capsule here, has not been reported that we know of, so for this product: detectable, window not established. The Cologne results set no upper limit, and anyone subject to testing should regard any contact with RAD-140 as a positive-test risk.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eShelf life for RAD-140 capsules has not been established in any published study we know of. Work to iMuscle's printed expiry or best-before date, where there is one, and to the age of any certificate.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the original pot.\u003c\/strong\u003e A certificate refers to the lot number printed on it, so capsules moved to another container can no longer be matched to one. Close the lid straight after each opening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCool, dry and dark.\u003c\/strong\u003e A cupboard away from radiators, kettles and bathrooms. Humidity is the chief threat: shells absorb water and turn soft and sticky, and moisture that reaches the powder can hasten chemical breakdown.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo temperature swings.\u003c\/strong\u003e A cold pot brought into a warm room gathers condensation; let it reach room temperature before opening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRecords.\u003c\/strong\u003e Note when the seal was first broken, and label anything removed from the pot with compound, lot and date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHandling.\u003c\/strong\u003e Gloves for opened capsules or spilled powder, no eating or drinking nearby, storage beyond the reach of children and animals, and disposal through chemical waste routes rather than household bins or drains.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator, a label for non-steroidal molecules developed to switch on the androgen receptor in some tissues, chiefly muscle and bone, while sparing others.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReference standard\u003c\/strong\u003e: material of known identity and purity, run alongside a sample for comparison.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC\u003c\/strong\u003e: high-performance liquid chromatography; the sample is pushed through a packed column and each component shows as a peak on the chromatogram, whose areas give the purity figure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLC-MS\u003c\/strong\u003e: the same separation followed by a mass spectrometer, which identifies each component by its mass.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtonated molecule\u003c\/strong\u003e: a molecule carrying one extra hydrogen ion, the form in which LC-MS registers RAD-140, at m\/z 394.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAssay\u003c\/strong\u003e: the test of how much RAD-140 a capsule holds, as opposed to how clean it is.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEster\u003c\/strong\u003e: an acid joined to an alcohol group by a bond that water can break; RAD-150 is RAD-140 joined in this way to benzoic acid.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdverse analytical finding\u003c\/strong\u003e: the formal term for a laboratory report of a prohibited substance in an athlete's sample.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: the rule that athletes answer for any prohibited substance in their sample, however it got there.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMarketing authorisation\u003c\/strong\u003e: a regulator's permission, in the UK from the MHRA, to sell a product as a medicine; RAD-140 has none.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/rad-140\"\u003eAll brands of RAD-140 (Testolone)\u003c\/a\u003e, compared on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/free-muscle-rad-140-testolone-10mg\"\u003eFree Muscle RAD-140 Testolone 10mg\u003c\/a\u003e, the own-brand pack, Janoshik-assayed batch by batch\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e, from animal studies to case reports\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eThis product is supplied for laboratory research use only. It is not a medicine, has not been evaluated by the MHRA, EMA or FDA, and is not for human consumption. Sold to adults aged 18 and over. Nothing on this page is medical, dosing or usage advice.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eMiller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-9. PMID: 24900290.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. PMID: 34565686.\u003c\/li\u003e\n\u003cli\u003eVan Wagoner RM, et al. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004-2010. PMID: 29183075.\u003c\/li\u003e\n\u003cli\u003eWagener F, et al. Human In Vivo Metabolism and Elimination Behavior of Micro-Dosed Selective Androgen Receptor Modulator RAD140 for Doping Control Purposes. Metabolites. 2022;12(7):666. PMID: 35888790.\u003c\/li\u003e\n\u003cli\u003eLeung K, et al. RAD-140 Drug-Induced Liver Injury. Ochsner J. 2022;22(4):361-365. PMID: 36561105.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468980203746,"sku":null,"price":49.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/TESTOLON.jpg?v=1789931418"},{"product_id":"thoroughbred-labs-rad140","title":"Thoroughbred Labs RAD-140","description":"\u003cp\u003eThoroughbred Labs RAD-140 is a 60-capsule pack of RAD-140 (testolone), a non-steroidal SARM, produced by Thoroughbred Labs and stocked by Free Muscle through \u003ca href=\"\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e. The manufacturer does not print a per-capsule milligram figure on the label, so the strength is listed as not stated. This listing is for laboratory research by adults aged 18 and over, and nothing here is guidance on use.\u003c\/p\u003e\u003ch2\u003eAbout RAD-140\u003c\/h2\u003e\u003cp\u003eRAD-140 (testolone) belongs to the SARM class: non-steroidal molecules that act as ligands at the androgen receptor. The molecule was first described in a 2011 paper from Radius Health, which described it as a potent, orally bioavailable, non-steroidal SARM and reported its characterisation in several preclinical models of anabolic androgen action (Miller et al., 2011). Those models were animal experiments, not human studies.\u003c\/p\u003e\u003cp\u003ePubChem records it under CAS number 1182367-47-0, formula C20H16ClN5O2, molecular weight 393.8 and InChIKey XMBUPPIEVAFYHO-KPZWWZAWSA-N. The systematic name, 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile, shows two defined stereocentres and no steroid ring system, and vosilasarm is listed among its synonyms.\u003c\/p\u003e\u003cp\u003eThe only published human trial is a Phase 1 dose-finding study in patients with hormone-receptor-positive metastatic breast cancer, reported in 2022 (LoRusso et al., 2022). Raised AST, ALT and bilirubin were among the most frequent adverse events, grade 3 or 4 adverse events occurred in 16 of the 22 patients, and the investigators identified a maximum tolerated dose. Two blood markers moved as expected for an androgen: sex hormone-binding globulin fell in every one of the 18 women tested and prostate-specific antigen rose in 16 of 20, which the investigators took as evidence that the receptor was engaged. The trial assessed tolerability and tumour response, not muscle or strength. Outside trials, case reports describe cholestatic liver injury in people who had taken products sold as RAD-140 (Leung et al., 2022), and hypogonadism in a man whose supplements contained RAD-140 together with other undeclared substances, so no single compound could be blamed (Chong et al., 2024). The findings summarised here describe the compound in research settings and are not claims about this product.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCompound: RAD-140 (Testolone)\u003c\/li\u003e\n\u003cli\u003eBrand: Thoroughbred Labs\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: not stated by the manufacturer on the label\u003c\/li\u003e\n\u003cli\u003eTotal per pack: cannot be calculated without a stated strength\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eBecause Thoroughbred Labs does not state the per-capsule content, this pack cannot be compared on milligrams with brands that do. A batch certificate, if available, may give a measured content. See \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003ehow to compare by milligram\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eRAD-140 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eMost UK searches for this compound, \"RAD 140 UK sale\" and \"testolone RAD 140 UK\" among them, come down to whether it can be bought lawfully and whether a given listing deserves trust. The legal answer is narrow. RAD-140 has no MHRA marketing authorisation, so it is not a licensed medicine in the UK; it is not an authorised food supplement; and it therefore cannot lawfully be sold for human consumption. Free Muscle sells it to adults aged 18 or over for laboratory research only. WADA prohibits it at all times under section S1 (anabolic agents), and buyers are responsible for the rules that apply to them, including any anti-doping code. The class as a whole is covered in \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eTrust matters because labels in this market have a poor record. Of 44 products bought online as SARMs in 2016 and analysed with WADA-approved procedures, only 23 (52 per cent) contained a SARM, 4 contained no active compound, 11 contained substances not on the label, and the measured amount matched the label in just 18 (41 per cent) (Van Wagoner et al., 2017). Those products came from other sellers, so the figures show the scale of the problem, not the contents of any particular pack. The table shows what a checkable listing includes.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eWhat to look for\u003c\/th\u003e\n\u003cth\u003eWhy it matters\u003c\/th\u003e\n\u003cth\u003eThis listing\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eNamed manufacturer and compound identifiers\u003c\/td\u003e\n\u003ctd\u003eA certificate can be matched to the right molecule\u003c\/td\u003e\n\u003ctd\u003eThoroughbred Labs; CAS number given above\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStated strength and capsule count\u003c\/td\u003e\n\u003ctd\u003eTotal content per pack can be worked out\u003c\/td\u003e\n\u003ctd\u003e60 capsules; strength not stated by the manufacturer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCertificate for the batch in stock\u003c\/td\u003e\n\u003ctd\u003eA generic document says nothing about your pack\u003c\/td\u003e\n\u003ctd\u003eShown only where Thoroughbred Labs supplies one for the batch we hold\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAccountable UK seller\u003c\/td\u003e\n\u003ctd\u003eSomeone to contact, an age check and a returns route\u003c\/td\u003e\n\u003ctd\u003eFreeMuscle LTD, Scunthorpe; 18+ only; unopened items returnable within 30 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTracked delivery in plain packaging\u003c\/td\u003e\n\u003ctd\u003eThe parcel can be followed and does not advertise its contents\u003c\/td\u003e\n\u003ctd\u003eFree tracked UK delivery in plain packaging on every order; EU delivery 3-7 working days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNo instructions for human use\u003c\/td\u003e\n\u003ctd\u003eA research compound cannot also be sold for consumption\u003c\/td\u003e\n\u003ctd\u003eNone given\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eOrders placed before 2pm Monday to Friday are processed the same working day; details are on our \u003ca href=\"\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages. Where a stated strength matters, the \u003ca href=\"\/collections\/rad-140\"\u003eRAD-140 collection\u003c\/a\u003e sets the brands we stock side by side, and our \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e applies the same tests to any shop.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eAny certificate of analysis for this product comes from Thoroughbred Labs, not from Free Muscle. Our policy for third-party brands is simple: we show a COA where the manufacturer supplies one for the batch we hold, and not otherwise. Email us to ask what documentation exists for the current batch before ordering. Free Muscle-brand compounds are batch-tested by the independent laboratory Janoshik Analytical; Thoroughbred Labs products are not in that programme. Where a certificate exists, read it field by field.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity\u003c\/strong\u003e: is the substance RAD-140? High-performance liquid chromatography (HPLC) compares its retention time with a reference standard; liquid chromatography with mass spectrometry (LC-MS) also measures molecular mass, and RAD-140 gives a protonated ion at m\/z 394 (Wagener et al., 2022). The compound named should match the CAS number and formula above.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity\u003c\/strong\u003e: a percentage, usually calculated from HPLC peak areas, stating how much of the material detected is RAD-140 rather than impurities. A high purity figure can sit alongside any quantity of compound per capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule\u003c\/strong\u003e: milligrams of RAD-140 actually found in a capsule. On an unlabelled pack like this one it is the only route to a total per pack and a price-per-milligram comparison.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch or lot number\u003c\/strong\u003e: the code on the certificate and the code on your pack should be identical.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest date and laboratory\u003c\/strong\u003e: show when and by whom the batch was analysed; an undated document cannot be tied to current stock.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThree gaps are common with third-party stock. If Thoroughbred Labs has supplied no certificate for the batch we hold, this listing makes no claim about identity, purity or content. If a certificate reports purity without content, it confirms the molecule but leaves the quantity per capsule unknown. If its batch number differs from the one on your pack, it describes other stock. See \u003ca href=\"\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e, and \u003ca href=\"\/pages\/contact\"\u003econtact us\u003c\/a\u003e if anything does not match.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eOther sellers offer RAD-140 as tablets or liquids, which is what searches for \"RAD 140 tablets UK\" and \"RAD 140 liquid UK\" reflect. Changing the format leaves the compound untouched but changes three practical things: how the quantity in each unit is set, where errors creep in, and what a batch analysis can prove. No published work compares the formats for RAD-140, so the table reflects general pharmaceutical practice.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eHow the amount per unit is set\u003c\/th\u003e\n\u003cth\u003eMain sources of error\u003c\/th\u003e\n\u003cth\u003eWhat a batch certificate can confirm\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCapsule\u003c\/td\u003e\n\u003ctd\u003eA measured powder fill, usually blended with a filler\u003c\/td\u003e\n\u003ctd\u003eUneven blending; variation in fill weight\u003c\/td\u003e\n\u003ctd\u003eIdentity, purity and content per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTablet\u003c\/td\u003e\n\u003ctd\u003eA powder blend compressed with binders\u003c\/td\u003e\n\u003ctd\u003eBlend uniformity; losses during compression and coating\u003c\/td\u003e\n\u003ctd\u003eIdentity, purity and content per tablet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLiquid\u003c\/td\u003e\n\u003ctd\u003eA stated concentration in a solvent, measured by volume\u003c\/td\u003e\n\u003ctd\u003eSolubility and stability in the solvent; accuracy of volume; solvent not always named\u003c\/td\u003e\n\u003ctd\u003eIdentity and concentration on the test date only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003ePeptides are amino acid chains that digestive enzymes break down, which is why research on peptides given by mouth is contested (see \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides work?\u003c\/a\u003e). RAD-140 has no such chain: it is a small heterocyclic molecule that its discoverers reported as orally bioavailable in animal models (Miller et al., 2011), a point of chemistry rather than a claim about this product. For this pack, the capsule's advantage as a discrete unit a laboratory can assay only becomes useful when a certificate reports measured content per capsule, because the label gives no strength.\u003c\/p\u003e\u003ch2\u003eRAD-140 compared with RAD-150 (TLB-150)\u003c\/h2\u003e\u003cp\u003eAmong comparison searches for this compound, \"RAD 140 vs RAD 150\" leads, with \"TLB 150 vs RAD 140\" asking the same thing under another name. RAD-150 is sold as the benzoate ester of RAD-140: the same core molecule with a benzoic acid group joined through an ester bond to its single hydroxyl group. Sellers present the ester as longer-acting, an idea borrowed from injectable testosterone esters that has not been tested for RAD-150 in any published study.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint of comparison\u003c\/th\u003e\n\u003cth\u003eRAD-140 (testolone)\u003c\/th\u003e\n\u003cth\u003eRAD-150 (TLB-150)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eWhat it is\u003c\/td\u003e\n\u003ctd\u003eNon-steroidal SARM, CAS 1182367-47-0\u003c\/td\u003e\n\u003ctd\u003eDescribed as the benzoate ester of RAD-140\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMechanism\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor agonist\u003c\/td\u003e\n\u003ctd\u003eNot studied; conversion to RAD-140 never measured\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubMed-indexed research\u003c\/td\u003e\n\u003ctd\u003e2011 discovery paper, a phase 1 cancer trial, anti-doping excretion work and liver injury case reports\u003c\/td\u003e\n\u003ctd\u003eNo relevant records in a search on 26 September 2026\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman data\u003c\/td\u003e\n\u003ctd\u003ePhase 1 trial in 22 women with breast cancer; excretion studies in adult men\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK status\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only, 18+\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only, 18+\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eNamed under S1.2, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eNot named, but S1.2 is not a closed list\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBrands we stock\u003c\/td\u003e\n\u003ctd\u003eFree Muscle, iMuscle, Yakka Strength, Thoroughbred Labs\u003c\/td\u003e\n\u003ctd\u003eFree Muscle only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eAn ester adds mass, so a milligram of RAD-150 contains less than a milligram of the RAD-140 core, and label strengths of the two are not interchangeable. Every statement about RAD-150's activity, timing or adverse effects is inferred from RAD-140 or from anecdote. We do not stock a Thoroughbred Labs RAD-150; the \u003ca href=\"\/collections\/rad-150\"\u003eRAD-150 collection\u003c\/a\u003e lists the brand we hold, and \u003ca href=\"\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150 (TLB-150)\u003c\/a\u003e covers the ester chemistry in more depth.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eIn sport the position is unambiguous. The WADA Prohibited List bans RAD-140 in and out of competition and names it among the examples in S1.2, other anabolic agents, so it would be expected to trigger a positive test in any tested sport. Every S1 substance is non-specified under the World Anti-Doping Code, which bears on sanctions, and athletes are strictly liable for their samples whether a finding came from deliberate use or a contaminated product.\u003c\/p\u003e\u003cp\u003eDetection times have been measured, though only after tiny exposures. A doping-control team at the German Sport University Cologne gave RAD-140 to adult male volunteers in six excretion studies of five people each and followed their urine by high-resolution LC-MS\/MS (Wagener et al., 2022). For the three single-application arms, the last sample still containing unchanged RAD-140 came at:\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eSingle amount given in the study\u003c\/th\u003e\n\u003cth\u003eLast detection of unchanged RAD-140 in urine\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e1 microgram\u003c\/td\u003e\n\u003ctd\u003e212 hours (almost 9 days)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e10 micrograms\u003c\/td\u003e\n\u003ctd\u003e240 hours (10 days)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e50 micrograms\u003c\/td\u003e\n\u003ctd\u003e696 hours (29 days)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eNothing above 50 micrograms was tested, and the authors noted that studies with larger amounts are still needed, so these times cannot be read as the longest possible window. For a capsule product the position is: detectable, window not established.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eThoroughbred Labs' packaging is the only source for an expiry date, where one is printed, and we know of no published study of RAD-140's stability in capsules. Keep the container sealed in a cool, dry place, out of direct light and away from heat such as radiators or sunny windowsills. Capsule shells respond to humidity in both directions: damp air makes gelatine tacky, so capsules cling together and moisture can reach the fill, while very dry storage can leave shells cracked.\u003c\/p\u003e\u003cp\u003eGood laboratory practice for this pack:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eLeave capsules in the manufacturer's container. The batch number printed on it is the only link between the capsules and any certificate.\u003c\/li\u003e\n\u003cli\u003eMark the dates of receipt and first opening on the label, and enter the batch in your lab records.\u003c\/li\u003e\n\u003cli\u003eWear nitrile gloves when handling capsules or their contents.\u003c\/li\u003e\n\u003cli\u003eSend surplus or expired material for disposal through your organisation's chemical waste arrangements.\u003c\/li\u003e\n\u003cli\u003eStore out of reach of children and animals, away from food and drink.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAndrogen receptor agonist\u003c\/strong\u003e: a compound that binds the androgen receptor and activates it, as testosterone does; RAD-140 is one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTissue selectivity\u003c\/strong\u003e: the design goal of a SARM, strong receptor activation in muscle and bone with weak activation in the prostate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCholestasis\u003c\/strong\u003e: reduced flow of bile from the liver, the pattern of injury described in several RAD-140 case reports.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTransaminases (AST and ALT)\u003c\/strong\u003e: enzymes released into the blood when liver cells are stressed or damaged.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetention time\u003c\/strong\u003e: the point at which a compound emerges from a chromatography column, compared with a reference standard in an identity test.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003em\/z\u003c\/strong\u003e: the mass-to-charge value a mass spectrometer assigns to an ion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent assay\u003c\/strong\u003e: measurement of how much compound a single unit, such as one capsule, holds, as distinct from its purity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBenzoate ester\u003c\/strong\u003e: a molecule joined to benzoic acid through an ester bond, which adds mass; RAD-150 is described as the benzoate ester of RAD-140.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-specified substance\u003c\/strong\u003e: a prohibited substance not regarded as likely to be taken for reasons other than performance; all S1 anabolic agents qualify.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMarketing authorisation\u003c\/strong\u003e: the MHRA licence a product needs before it can be sold as a medicine in the UK.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/rad-140\"\u003eAll brands of RAD-140 (Testolone)\u003c\/a\u003e, compared on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/brand-thoroughbred-labs\"\u003eAll Thoroughbred Labs products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/rad-150\"\u003eRAD-150 (TLB-150)\u003c\/a\u003e and the wider \u003ca href=\"\/collections\/sarms\"\u003eSARMs range\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e, covering the liver injury case reports\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eThis product is supplied for laboratory research use only. It is not a medicine, has not been evaluated by the MHRA, EMA or FDA, and is not for human consumption. Sold to adults aged 18 and over. Nothing on this page is medical, dosing or usage advice.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eMiller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-9. PMID: 24900290.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. PMID: 34565686.\u003c\/li\u003e\n\u003cli\u003eVan Wagoner RM, et al. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004-2010. PMID: 29183075.\u003c\/li\u003e\n\u003cli\u003eWagener F, et al. Human In Vivo Metabolism and Elimination Behavior of Micro-Dosed Selective Androgen Receptor Modulator RAD140 for Doping Control Purposes. Metabolites. 2022;12(7):666. PMID: 35888790.\u003c\/li\u003e\n\u003cli\u003eLeung K, et al. RAD-140 Drug-Induced Liver Injury. Ochsner J. 2022;22(4):361-365. PMID: 36561105.\u003c\/li\u003e\n\u003cli\u003eChong S, et al. Reversible Gynecomastia and Hypogonadism Due to Usage of Commercial Performance-Enhancing Supplement Use. JCEM Case Rep. 2024;2(8):luae148. PMID: 39145153.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Thoroughbred Labs","offers":[{"title":"Default Title","offer_id":48468980564194,"sku":null,"price":44.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/RAD.png?v=1789931429"},{"product_id":"yakka-strength-yakka-strength-rad140","title":"Yakka Strength RAD-140","description":"\u003cp\u003eYakka Strength RAD-140 is a 60-capsule pack of the selective androgen receptor modulator RAD-140, also known as testolone, manufactured by Yakka Strength and stocked by Free Muscle as part of the Muscle Market range. Yakka Strength does not state a per-capsule strength on the label, so we do not quote one.\u003c\/p\u003e\u003ch2\u003eAbout RAD-140\u003c\/h2\u003e\u003cp\u003eRAD-140 is a non-steroidal selective androgen receptor modulator (SARM). It was designed by Radius Health as an orally active compound that binds the androgen receptor and, in preclinical work, showed a stronger effect on skeletal muscle than on the prostate. The 2011 characterisation paper described it as potent and orally bioavailable and reported its activity in several preclinical animal models of anabolic androgen action. Animal results do not show how it behaves in people.\u003c\/p\u003e\u003cp\u003eClinical data are limited to a single first-in-human Phase 1 study in 22 postmenopausal women with ER-positive, HER2-negative metastatic breast cancer, published in 2022. The investigators described the safety profile as acceptable, but raised liver enzymes (AST in 59.1 per cent of participants, ALT in 45.5 per cent) and raised bilirubin were the most frequent treatment-emergent adverse events, and 16 of the 22 had a grade 3 or 4 event. The same study measured an elimination half-life of 44.7 hours. Sex hormone-binding globulin fell in all 18 participants in whom it was measured and prostate-specific antigen rose in 16 of 20, markers that the androgen receptor was being engaged well beyond muscle.\u003c\/p\u003e\u003cp\u003eRAD-140 has never been approved as a medicine anywhere in the world. Nothing in these studies is a claim about this product.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIdentifier\u003c\/th\u003e\n\u003cth\u003eRAD-140\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOther names\u003c\/td\u003e\n\u003ctd\u003eTestolone, vosilasarm, EP0062\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e1182367-47-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular formula\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e393.8 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInChIKey\u003c\/td\u003e\n\u003ctd\u003eXMBUPPIEVAFYHO-KPZWWZAWSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e44200882\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eIdentifiers are from PubChem. The formula and molecular weight are the values to check a mass-spectrometry result against.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCompound: RAD-140 (Testolone)\u003c\/li\u003e\n\u003cli\u003eBrand and manufacturer: Yakka Strength\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: not stated by the manufacturer on the label\u003c\/li\u003e\n\u003cli\u003eTotal per pack: cannot be calculated without a stated strength\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWith no printed milligram figure, this pack cannot be set against RAD-140 brands that state one; for those, the method is in \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003ehow to compare by milligram\u003c\/a\u003e. A measured content, where a batch certificate gives one, is covered below.\u003c\/p\u003e\u003ch2\u003eRAD-140 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"RAD 140 UK\" and \"RAD140 for sale UK\" ask two things: is buying it lawful, and how is a sound listing told apart from a poor one.\u003c\/p\u003e\u003ch3\u003eThe legal position\u003c\/h3\u003e\u003cp\u003eRAD-140 is not a controlled drug in the UK. It sits outside both routes by which a substance can be sold for people: the MHRA has never granted it a marketing authorisation, so it cannot be sold as a medicine, and it is not an authorised food supplement, so it cannot be sold as food. What remains is sale as a research compound for laboratory work, the only basis on which Free Muscle lists it, and only to buyers aged 18 or over. WADA bans it at all times, so a tested athlete stands in a different position from a laboratory buyer. Buyers are responsible for the rules that apply to them. Background on the class is in \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eWhy the listing matters\u003c\/h3\u003e\u003cp\u003eResearchers at LGC in Fordham, Cambridgeshire, bought a range of products sold to UK consumers as SARMs and analysed them by high-resolution mass spectrometry. One contained no active ingredient, others contained prohibited substances not declared on the label, and where a SARM was present the measured amount differed from the packaging. The paper also notes that neither the European Medicines Agency nor the US Food and Drug Administration has approved any SARM. Because a label alone guarantees nothing, a trustworthy UK listing shows:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eA batch or lot number\u003c\/strong\u003e on the pack that can be matched to a certificate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for that batch\u003c\/strong\u003e, with identity, purity and a test date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated strength per capsule\u003c\/strong\u003e, so the total per pack can be worked out and checked.\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eA named manufacturer and a traceable UK seller.\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-use terms\u003c\/strong\u003e: an 18+ restriction and no usage instructions or outcome claims.\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eTracked delivery in plain packaging.\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eHow this listing measures up\u003c\/h3\u003e\u003cp\u003eOn most points, not all. The manufacturer is named, and the seller is FreeMuscle LTD, a UK company in Scunthorpe. Every order goes by free tracked UK delivery in plain packaging, orders placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3-7 working days, and unopened items can be returned within 30 days. The gap is the third point: with no strength on the label, only a batch certificate can supply a content figure. Forum and Reddit threads found by searches like \"RAD 140 UK review\" cannot show what a given pack contained. More checks are in \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eRAD-140 is sold as capsules, pressed tablets and \"research liquids\", hence searches for \"RAD 140 tablets\" and \"RAD 140 liquid UK\". The molecule is the same in each; what differs is how well each format holds it and how precisely each unit is measured.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsules.\u003c\/strong\u003e A weighed or volume-filled quantity of powder, usually blended with a filler, is sealed in a shell. The amount per unit is fixed at manufacture, so its accuracy depends on how evenly the blend was mixed and filled. A dry powder in a closed shell is the least exposed of the three formats to moisture and oxygen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTablets.\u003c\/strong\u003e Powder is compressed with binders. The content per unit is also fixed at manufacture and depends on the same blending step, with compression adding further excipients.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquids.\u003c\/strong\u003e The content per millilitre depends on the compound dissolving completely and staying in solution, and every measured volume is only as accurate as the dropper or pipette used. Compounds in solution are generally more open to degradation than dry solids, and concentration drifts if solvent evaporates.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eRAD-140 is a small molecule of about 394 daltons, not a peptide, so the digestion problem that limits peptides given by mouth does not apply to it (see \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e). Its discoverers described it as orally bioavailable in animal models, and the published human data concern oral administration only. None of this says that any form produces an effect. For laboratory purposes the practical difference is verification: a capsule certificate can report content per unit, a liquid certificate reports concentration, and either has to match its own batch.\u003c\/p\u003e\u003ch2\u003eRAD-140 compared with RAD-150\u003c\/h2\u003e\u003cp\u003e\"RAD 140 vs RAD 150\" is the comparison most often searched for this compound. RAD-150, also sold as TLB-150, is not a separate drug programme. PubChem records it as TLB 150 benzoate (CID 68547459): RAD-140 with a benzoate group joined as an ester to its hydroxyl group. It appears as a numbered compound in US patent 8,629,167, but a PubMed search under RAD-150, TLB-150 and related names returns no study of it.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint\u003c\/th\u003e\n\u003cth\u003eRAD-140\u003c\/th\u003e\n\u003cth\u003eRAD-150 (TLB-150)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eChemical type\u003c\/td\u003e\n\u003ctd\u003eNon-steroidal SARM\u003c\/td\u003e\n\u003ctd\u003eBenzoate ester of RAD-140\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2\u003c\/td\u003e\n\u003ctd\u003eC27H20ClN5O3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e393.8\u003c\/td\u003e\n\u003ctd\u003e497.9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eComputed XLogP3\u003c\/td\u003e\n\u003ctd\u003e3.1\u003c\/td\u003e\n\u003ctd\u003e5.4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAnimal studies\u003c\/td\u003e\n\u003ctd\u003ePreclinical animal data, 2011\u003c\/td\u003e\n\u003ctd\u003eNone published\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman studies\u003c\/td\u003e\n\u003ctd\u003eOne Phase 1 trial (22 women); anti-doping excretion studies\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK status\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research compound\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research compound\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eNamed in S1.2\u003c\/td\u003e\n\u003ctd\u003eNot named; within S1.2 wording\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThree things follow from the structure. The RAD-140 portion makes up about 79 per cent of the ester by mass, so label milligrams of the two are not interchangeable figures. The ester is markedly more fat-soluble on computed values. And an ester bond can be split by water, which makes humidity and heat more relevant to its storage. Claims that RAD-150 is longer-acting or stronger have never been measured, and whether it is converted to RAD-140 in a living system has not been reported.\u003c\/p\u003e\u003cp\u003eIn sport, RAD-140 is named in section S1.2 of the WADA Prohibited List; RAD-150 is not, but S1.2 opens with the words \"including, but not limited to\", so an unnamed SARM derivative is not outside it. Brands held are in the \u003ca href=\"\/collections\/rad-150\"\u003eRAD-150 (TLB-150) collection\u003c\/a\u003e, and the chemistry is set out at length in \u003ca href=\"\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150 (TLB-150)\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eAny certificate of analysis (COA) for this product is Yakka Strength's, since they make it. Our rule for their stock: a COA appears only when the manufacturer has supplied one for the batch we hold. If one exists for the current batch it is linked here or sent by email on request; if not, we say so rather than substitute a generic PDF. Free Muscle-brand batches, such as \u003ca href=\"\/products\/free-muscle-rad-140-testolone-10mg\"\u003eFree Muscle RAD-140 Testolone 10mg\u003c\/a\u003e, are independently assayed at Janoshik Analytical; that does not extend to Yakka Strength. Where a Yakka Strength certificate exists, read these fields.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity.\u003c\/strong\u003e Confirms the sample is RAD-140. By HPLC, identity rests on the main peak matching the retention time of a reference standard. LC-MS is stronger: RAD-140 gives a protonated molecule at m\/z 394, the ion anti-doping chemists track in urine, while an ion near m\/z 498, calculated for RAD-150, would point to the ester.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e Usually an HPLC area percentage, the share of detected material that is RAD-140. It describes the compound, not the capsule, and says nothing about how much RAD-140 each capsule holds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e The key line for this product, since the label states no strength: a measured milligram figure per capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number.\u003c\/strong\u003e Must match the lot printed on the pack.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest date and laboratory.\u003c\/strong\u003e The date shows how old the result is; the laboratory name allows the report to be checked with its issuer.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eFor this brand, a missing field has a specific meaning. No identity result leaves the compound unconfirmed; purity without content leaves the strength unknown; no batch number means the document does not verify the pack in hand. If a field is missing, \u003ca href=\"\/pages\/contact\"\u003econtact us\u003c\/a\u003e and we will say what exists for the current stock. Method is covered in \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ereading a COA\u003c\/a\u003e and on our \u003ca href=\"\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eRAD-140 is prohibited at all times, in and out of competition, under section S1.2 (other anabolic agents) of the WADA Prohibited List, where it is named as an example of a SARM. Anti-doping rules apply strict liability: an athlete is responsible for any prohibited substance found in their sample, whatever its source.\u003c\/p\u003e\u003cp\u003eThe most detailed human elimination data come from a 2022 study at the German Sport University Cologne. In six controlled excretion studies, each with five adult male volunteers given very small amounts of RAD-140, urine was analysed by LC-HRMS\/MS. Concentrations peaked two to six hours after administration and then fell slowly. Unchanged RAD-140 remained detectable for up to 29 days after a single administration of the largest amount studied, and it accumulated when administration was repeated on consecutive days. The parent compound was detectable for longest, and several metabolites were described in human urine for the first time. The authors framed the work partly around contaminated supplements, which can also cause positive findings.\u003c\/p\u003e\u003cp\u003eNo published study gives a detection window for the quantities in commercial capsules, so for this product the accurate statement is: detectable, window not established. For anyone in a tested sport, any exposure carries the risk of a positive test.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eKeep the pack sealed in its original container, closed between openings, in a cool, dry cupboard away from direct light and heat. Moisture is the main risk to capsules: capsule shells, gelatine ones in particular, soften and stick together in humid air and turn brittle when very dry, and damp powder degrades faster than dry. Heat speeds up both. Do not decant capsules into unlabelled containers: the batch number on the original pack is what ties the contents to a certificate.\u003c\/p\u003e\u003cp\u003eWe are not aware of published stability data for RAD-140 in capsule form, so the expiry or best-before date on the pack, where printed, is the limit to work within. Note the date the pack was first opened next to the batch number. Ordinary laboratory good practice applies: wear gloves when handling opened capsules or powder, work away from food and drink, keep the pack out of reach of children and animals, label any sample taken from the pack with compound, batch and date, and dispose of unwanted material as chemical waste, not via household bins or drains.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator, a non-steroidal androgen receptor ligand designed to act more on muscle and bone than on the prostate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAndrogen receptor\u003c\/strong\u003e: the nuclear receptor activated by testosterone and dihydrotestosterone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTestolone and vosilasarm\u003c\/strong\u003e: other names for RAD-140; testolone is an informal market name, vosilasarm the non-proprietary name used in reference databases such as PubChem.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEster\u003c\/strong\u003e: a compound formed by joining an acid to an alcohol group; RAD-150 is the benzoic acid ester of RAD-140.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHalf-life\u003c\/strong\u003e: the time taken for the concentration of a compound in the blood to fall by half.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhase 1 trial\u003c\/strong\u003e: the first stage of human testing, focused on tolerability and pharmacokinetics in a small group.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC\u003c\/strong\u003e: high-performance liquid chromatography, which separates a sample into its components; the usual basis of a purity figure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLC-MS\u003c\/strong\u003e: liquid chromatography with mass spectrometry, which also measures molecular mass and so gives firmer proof of identity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCertificate of analysis (COA)\u003c\/strong\u003e: a laboratory report on one specific batch, carrying its batch number and test date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWADA S1.2\u003c\/strong\u003e: the Prohibited List section for other anabolic agents, including SARMs, banned at all times.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMHRA\u003c\/strong\u003e: the Medicines and Healthcare products Regulatory Agency.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/rad-140\"\u003eRAD-140 (Testolone) collection\u003c\/a\u003e: every brand we stock, side by side on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/brand-yakka-strength\"\u003eAll Yakka Strength products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/sarms\"\u003eSARMs\u003c\/a\u003e, the wider range\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e, including the reported side effects\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eYakka Strength RAD-140 is supplied for laboratory research use only. It is not a medicine or a food supplement, has not been evaluated by the MHRA, EMA or FDA, and is not for human consumption. Sale is restricted to adults aged 18 and over. Nothing on this page is medical, dosing or usage advice.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eMiller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-9. PMID: 24900290.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. PMID: 34565686.\u003c\/li\u003e\n\u003cli\u003eLeaney AE, et al. Analysis of supplements available to UK consumers purporting to contain selective androgen receptor modulators. Drug Test Anal. 2021;13(1):122-127. PMID: 32748554.\u003c\/li\u003e\n\u003cli\u003eWagener F, et al. Human In Vivo Metabolism and Elimination Behavior of Micro-Dosed Selective Androgen Receptor Modulator RAD140 for Doping Control Purposes. Metabolites. 2022;12(7):666. PMID: 35888790.\u003c\/li\u003e\n\u003cli\u003eBasaria S, et al. The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci. 2013;68(1):87-95. PMID: 22459616.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Yakka Strength","offers":[{"title":"Default Title","offer_id":48468982792418,"sku":null,"price":64.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/yakka-strength-research-capsule-frontview_600x_279ef740-de0d-47fe-83d8-e2ad3e157ee7.png?v=1789931448"}],"url":"https:\/\/freemuscle.co.uk\/collections\/rad-140.oembed","provider":"Free Muscle","version":"1.0","type":"link"}