{"title":"RAD-150 (TLB-150)","description":"\u003cp\u003eRAD-150, sold under the name TLB-150 and sometimes written RAD150 or TLB150, is marketed as an esterified derivative of the selective androgen receptor modulator RAD-140 (testolone). The ester group is said by its sellers to slow release of the parent molecule, though no peer-reviewed study has examined this. This page lists every brand of RAD-150 stocked at Free Muscle, compared on strength per capsule, capsules per pack and batch testing, and sets out honestly how thin the published evidence for this compound is.\u003c\/p\u003e\n\u003ch2\u003eWhat is RAD-150?\u003c\/h2\u003e\n\u003cp\u003eRAD-150 is described by its manufacturers as a benzoate ester of RAD-140, a non-steroidal SARM first reported by Radius Health in 2011. In pharmacology, esterification is a familiar technique: attaching an ester group to a molecule that carries a free hydroxyl often makes it more fat-soluble, so that it is released more slowly and acts for longer once the ester is cleaved by esterase enzymes. Whether RAD-150 actually behaves this way in any biological system has not been tested in the published literature. The compound did not originate in a pharmaceutical development programme, has no development code from a recognised company, and appeared first in grey-market catalogues.\u003c\/p\u003e\n\u003cp\u003eEverything that can be said with any confidence about its mechanism is inherited from the parent molecule. RAD-140 binds the androgen receptor with high affinity and was designed for tissue selectivity, favouring muscle and bone over prostate. If RAD-150 is hydrolysed to RAD-140 in vivo, its receptor pharmacology would be expected to follow, but the rate and extent of that conversion, and the fate of the benzoate fragment, are unknown.\u003c\/p\u003e\n\u003cp\u003eRAD-150 has no human trial data, no published animal data, and has never been submitted for approval anywhere. It holds no marketing authorisation from the MHRA, EMA or FDA and is not a medicine in any jurisdiction.\u003c\/p\u003e\n\u003ch2\u003eWhat the published research reports\u003c\/h2\u003e\n\u003cp\u003eA PubMed search for RAD-150 or TLB-150 returns no controlled studies, no pharmacokinetic work and no case reports. Because of this, the only relevant evidence is the literature on RAD-140, and even that must be read with the caveat that an ester is a different chemical entity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRAD-140 discovery paper (2011).\u003c\/strong\u003e Miller and colleagues described the design, synthesis and preclinical characterisation of RAD140 as a potent, orally bioavailable, non-steroidal SARM, tested in several animal models of anabolic androgen action. No human data are included.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRAD-140 first-in-human study (2022).\u003c\/strong\u003e LoRusso and colleagues reported a phase 1 dose-escalation study of RAD140 in 22 postmenopausal women with ER-positive, HER2-negative metastatic breast cancer. Elevated AST (59.1 per cent), elevated ALT (45.5 per cent) and raised bilirubin (27.3 per cent) were the most common treatment-emergent adverse events, and grade 3 or 4 events occurred in 72.7 per cent of patients. Clinical benefit rate at 24 weeks was 18.2 per cent. This is the only human study of the parent compound.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUK market analysis of SARM products (2021).\u003c\/strong\u003e Leaney and colleagues, working in a UK laboratory, purchased supplement products marketed as SARMs to UK consumers and analysed them by high-resolution mass spectrometry. They found discrepancies ranging from products with no active ingredient at all to products containing undeclared prohibited substances, and where a SARM was present its measured concentration often differed from the label. The authors noted that no SARM has yet gained clinical approval from the EMA or FDA and that toxicity data, especially for combinations, are incomplete.\u003c\/p\u003e\n\u003cp\u003eThese findings describe study participants, laboratory animals and purchased products from other suppliers. None of them is a claim about the RAD-150 listed on this page, and none of the RAD-140 findings can be assumed to transfer to the ester.\u003c\/p\u003e\n\u003ch2\u003eBrands of RAD-150 we stock\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree Muscle RAD-150 (TLB-150), Bioreactive Series, 25mg, 60 capsules.\u003c\/strong\u003e Our own brand, capsule form, 1,500mg of compound per pack. Every batch is assayed by Janoshik Analytical and the certificate for your batch is available by email on request. \u003ca href=\"\/products\/rad-150-tlb-150-bioreactive-series\"\u003eView the Free Muscle RAD-150 listing\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eRAD-150 is currently a single-brand line at Free Muscle. Third-party brands in the Muscle Market range (iMuscle, Yakka Strength, Thoroughbred Labs and BioLab) do not supply it at present. If that changes, additional listings will appear here with their own COA status.\u003c\/p\u003e\n\u003ch3\u003eHow to compare them\u003c\/h3\u003e\n\u003cp\u003eWith one brand on the page the comparison is against the RAD-140 collection rather than between RAD-150 products. Compute total milligrams per pack (strength per capsule multiplied by capsules per pack), divide the price by that figure for cost per milligram, and remember that a milligram of the ester contains proportionally less of the parent molecule because the benzoate group adds mass. Above all, check the batch certificate: with a compound this poorly characterised, an independent identity and purity assay is the only objective information available. Our guide to \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e covers the arithmetic.\u003c\/p\u003e\n\u003ch2\u003eBatch testing and certificates of analysis\u003c\/h2\u003e\n\u003cp\u003eA certificate of analysis (COA) answers the two questions that matter about a RAD-150 capsule: is the compound what the label says, and how much is present. A genuine batch certificate is issued by an independent laboratory, names the lot number, and reports identity (by HPLC or mass spectrometry against a reference standard) and assayed purity or content.\u003c\/p\u003e\n\u003cp\u003eEvery Free Muscle-brand batch is assayed by Janoshik Analytical, an independent laboratory, and the certificate for the batch you receive is sent on request by email. For other brands we show a COA only where the manufacturer has supplied one for the batch we hold. A generic PDF with no batch number, or one dated long before the product was made, is not a batch certificate and tells you nothing about the capsules in your hand. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab tests page\u003c\/a\u003e explains how to read a Janoshik certificate and match it to your batch.\u003c\/p\u003e\n\u003ch2\u003eLegal status in the UK\u003c\/h2\u003e\n\u003cp\u003eRAD-150 is not a licensed medicine in the United Kingdom. It has never been granted a marketing authorisation by the MHRA, and it is not an authorised food supplement or a permitted novel food ingredient. It cannot legally be sold or labelled for human consumption. Free Muscle sells RAD-150 to adults aged 18 or over for laboratory and research purposes only, and every listing states this. Although RAD-150 is not named individually on the World Anti-Doping Agency Prohibited List, section S1.2 (Other Anabolic Agents) lists SARMs by example and covers other substances with a similar chemical structure or similar biological effect, so an ester of RAD-140 is prohibited at all times. Anyone subject to anti-doping rules should treat any product in this class as prohibited at all times, in and out of competition. For a fuller overview of the class, see our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eresearch guide to SARMs\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eStorage and handling\u003c\/h2\u003e\n\u003cp\u003eKeep RAD-150 capsules in the original sealed container in a cool, dry place away from light and heat. Do not decant into unlabelled containers, and record the batch number so that a COA request can be matched to the exact material. Keep out of reach of children and pets, and follow standard laboratory good practice: gloves when handling, no eating or drinking in the work area, and disposal in line with local rules for research chemicals.\u003c\/p\u003e\n\u003ch2\u003eDelivery and returns\u003c\/h2\u003e\n\u003cp\u003eEvery RAD-150 order is sent from our UK base (FreeMuscle LTD, Scunthorpe) with free tracked delivery to any UK address, in plain packaging. Orders placed before 2pm Monday to Friday are processed the same working day, and EU orders normally arrive within 3 to 7 working days. Unopened items may be returned within 30 days. Customers must be 18 or over. See the \u003ca href=\"\/pages\/shipping\"\u003eshipping page\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eguarantee page\u003c\/a\u003e for the full terms.\u003c\/p\u003e\n\u003ch2\u003eRelated reading\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/sarms-explained-how-selective-androgen-receptor-modulators-work-1135-86\"\u003eSARMs explained: how selective androgen receptor modulators work\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003eHow to read a certificate of analysis\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/what-is-janoshik-analytical\"\u003eWhat is Janoshik Analytical?\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eRelated collections: \u003ca href=\"\/collections\/rad-140\"\u003eRAD-140 (Testolone)\u003c\/a\u003e, \u003ca href=\"\/collections\/bioreactive-series\"\u003eBioreactive Series\u003c\/a\u003e, \u003ca href=\"\/collections\/yk-11\"\u003eYK-11\u003c\/a\u003e, \u003ca href=\"\/collections\/sarms\"\u003eall SARMs\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eRAD-150 is sold strictly for laboratory research use only. It is not a licensed medicine, has not been evaluated or approved by the MHRA, EMA or FDA, is not a food supplement and is not for human consumption. Buyers must be 18 or over. Nothing on this page is medical advice, dosing advice or a recommendation to use this compound in any way; the published findings summarised above describe study participants and laboratory models, not the products listed.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"rad-150-tlb-150-bioreactive-series","title":"RAD-150 (TLB-150) — Bioreactive Series","description":"\u003cp\u003e\u003cstrong\u003eRAD-150 (TLB-150) — Bioreactive Series.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eRAD-150 is a benzoate-ester form of RAD-140 (Testolone), a selective androgen receptor modulator. A benzoate ester generally slows release of the parent compound — that is a chemistry property, not a promised outcome. Neither compound has the clinical data to support a comparison of human results, and we are not going to invent one.\u003c\/p\u003e\u003cp\u003eSARMs have been associated with liver injury and testosterone suppression in published case reports. RAD-150 is \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e and is prohibited in sport by WADA.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e Not a medicine or dietary supplement, not evaluated by the MHRA, EMA or FDA, not for human consumption.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":47040801865954,"sku":"10000000","price":69.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/IMG-2551.jpg?v=1766262716"}],"url":"https:\/\/freemuscle.co.uk\/collections\/rad-150.oembed","provider":"Free Muscle","version":"1.0","type":"link"}