{"title":"SARMs","description":"\u003cp\u003eThis collection lists the selective androgen receptor modulators (SARMs) and SARM-adjacent research compounds we sell and dispatch from the UK. Free Muscle's own label covers RAD-140 (Testolone), RAD-150 (TLB-150), YK-11 and Cardarine (GW-501516); through Muscle Market we add LGD-4033, Ostarine (MK-2866), Andarine (S-4), S-23 and SR9009, plus other brands' RAD-140, YK-11 and Cardarine, from iMuscle, Thoroughbred Labs and Yakka Strength. All are supplied as capsules for laboratory research. Every Free Muscle batch is assayed by Janoshik Analytical, an independent laboratory, with the Certificate of Analysis available on request; for other brands we show a certificate only where the manufacturer supplies one for the batch we hold. Nothing here is a medicine or a food supplement.\u003c\/p\u003e\n\u003ch2\u003eWhy researchers order from Free Muscle\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEvery Free Muscle-brand batch is assayed by Janoshik Analytical, an independent laboratory, and we send the certificate for your batch on request.\u003c\/li\u003e\n\u003cli\u003eUK delivery is free and tracked on every order, with no minimum spend, and usually arrives 2-3 working days after dispatch; faster tracked UK delivery costs £6 and usually takes 1-2 working days.\u003c\/li\u003e\n\u003cli\u003eOrders placed before 2pm Monday to Friday are processed the same working day.\u003c\/li\u003e\n\u003cli\u003eUnopened items can be returned within 30 days.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhat this collection covers\u003c\/h2\u003e\n\u003cp\u003eSARMs are non-steroidal (and, in the case of YK-11, steroidal) ligands designed to bind the androgen receptor with tissue selectivity. They were developed by pharmaceutical companies from the late 1990s onwards, and none has been approved as a medicine anywhere. Each compound below has its own page comparing every brand we hold by strength, pack size and batch testing.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 (Testolone)\u003c\/a\u003e, a non-steroidal SARM that reached early clinical study; Free Muscle stocks 10 mg capsules, 60 per pack.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/rad-150\"\u003eRAD-150 (TLB-150)\u003c\/a\u003e, described in trade literature as an ester-modified derivative of RAD-140, with no published human trial data; 25 mg capsules, 60 per pack, from the Bioreactive Series.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/yk-11\"\u003eYK-11\u003c\/a\u003e, a steroidal compound reported in cell studies as a partial androgen receptor agonist that also affected myostatin-related signalling; 10 mg capsules, 60 per pack.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eCardarine (GW-501516)\u003c\/a\u003e, strictly a PPAR-delta agonist rather than a SARM, grouped here by convention; 5 mg and 10 mg capsules, 60 per pack. Its pharmaceutical development stopped after rodent carcinogenicity findings.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe grid above also shows other brands' \u003ca href=\"\/en-ro\/collections\/lgd-4033\"\u003eLGD-4033\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/ostarine\"\u003eOstarine (MK-2866)\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/andarine\"\u003eAndarine (S-4)\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/s-23\"\u003eS-23\u003c\/a\u003e and \u003ca href=\"\/en-ro\/collections\/sr9009\"\u003eSR9009\u003c\/a\u003e, listed through Muscle Market, alongside their RAD-140, YK-11 and Cardarine.\u003c\/p\u003e\n\u003ch3\u003ePrice per capsule and per milligram\u003c\/h3\u003e\n\u003cp\u003eFree Muscle packs at the prices on 16 October 2026, lowest price per milligram first. Other brands' prices per milligram are on each compound page.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eListing\u003c\/th\u003e\n\u003cth\u003ePrice\u003c\/th\u003e\n\u003cth\u003ePer capsule\u003c\/th\u003e\n\u003cth\u003ePer mg\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003ca href=\"\/en-ro\/products\/rad-150-tlb-150-bioreactive-series\"\u003eRAD-150\u003c\/a\u003e 25mg × 60\u003c\/td\u003e\n\u003ctd\u003e£69.99\u003c\/td\u003e\n\u003ctd\u003e£1.17\u003c\/td\u003e\n\u003ctd\u003e£0.047\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003ca href=\"\/en-ro\/products\/cardarine-gw-501516-10mg-free-muscle-60-capsules\"\u003eCardarine\u003c\/a\u003e 10mg × 60\u003c\/td\u003e\n\u003ctd\u003e£39.99\u003c\/td\u003e\n\u003ctd\u003e£0.67\u003c\/td\u003e\n\u003ctd\u003e£0.067\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003ca href=\"\/en-ro\/products\/yk-11-10mg\"\u003eYK-11\u003c\/a\u003e 10mg × 60\u003c\/td\u003e\n\u003ctd\u003e£49.99\u003c\/td\u003e\n\u003ctd\u003e£0.83\u003c\/td\u003e\n\u003ctd\u003e£0.083\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003ca href=\"\/en-ro\/products\/free-muscle-rad-140-testolone-10mg\"\u003eRAD-140\u003c\/a\u003e 10mg × 60\u003c\/td\u003e\n\u003ctd\u003e£49.99\u003c\/td\u003e\n\u003ctd\u003e£0.83\u003c\/td\u003e\n\u003ctd\u003e£0.083\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003ca href=\"\/en-ro\/products\/cardarine-5mg-free-muscle\"\u003eCardarine\u003c\/a\u003e 5mg × 60\u003c\/td\u003e\n\u003ctd\u003e£29.99\u003c\/td\u003e\n\u003ctd\u003e£0.50\u003c\/td\u003e\n\u003ctd\u003e£0.100\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eWhat the published research reports\u003c\/h2\u003e\n\u003cp\u003eHuman data on SARMs is limited to short trials of a few compounds. In a 21-day placebo-controlled study of LGD-4033 in 76 healthy young men, lean body mass rose in a dose-dependent way while total testosterone and sex hormone-binding globulin fell, and the authors noted that longer studies were needed to assess safety. A 2019 review concluded that no SARM has completed the trials needed for approval, and that reports of liver injury and hormonal suppression accompany their unregulated use. None of this is a claim about the products on this page.\u003c\/p\u003e\n\u003ch2\u003eBatch testing and certificates of analysis\u003c\/h2\u003e\n\u003cp\u003eA Certificate of Analysis (COA) records what an independent laboratory found in a specific batch: the identity of the compound and its measured purity. Every Free Muscle-brand batch is assayed by Janoshik Analytical, and the batch number is printed on the pack. Email us with that number and we will send the certificate for your batch. A generic PDF without a batch number is not a batch certificate. See \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003ehow we test\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eWhere to buy SARMs in the UK: how to check a supplier\u003c\/h2\u003e\n\u003cp\u003eWhichever shop you buy SARMs from, check these five points before you order:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eA batch number and a certificate for that batch.\u003c\/strong\u003e The pack should carry a batch number, and the seller should be able to show a certificate of analysis for that same batch from a named laboratory, with the test date. Every Free Muscle-brand batch is assayed by Janoshik Analytical, and we send the certificate for your batch on request.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe strength per capsule and the capsule count.\u003c\/strong\u003e With both figures you can work out the total milligrams in the pack and the price per milligram; the price table above does this for our own packs. If a listing does not state one of them, ask the seller before you order.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-use labelling and an age check.\u003c\/strong\u003e A research compound should be sold for laboratory research use only, not for human consumption, to adults aged 18 or over, with no dosing or usage advice. That is how every listing here is sold.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrices in pounds sterling and tracked UK dispatch.\u003c\/strong\u003e UK delivery from us is free and tracked on every order, with no minimum spend, and usually arrives 2-3 working days after dispatch; orders placed before 2pm Monday to Friday are processed the same working day.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA clear returns policy.\u003c\/strong\u003e Unopened items can be returned to us within 30 days.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eBrands on this page: \u003ca href=\"\/en-ro\/collections\/brand-free-muscle\"\u003eFree Muscle\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/brand-thoroughbred-labs\"\u003eThoroughbred Labs\u003c\/a\u003e and \u003ca href=\"\/en-ro\/collections\/brand-yakka-strength\"\u003eYakka Strength\u003c\/a\u003e. The \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003ehow we test\u003c\/a\u003e go into more detail.\u003c\/p\u003e\n\n\u003ch2\u003eLegal status in the UK\u003c\/h2\u003e\n\u003cp\u003eNo SARM is a licensed medicine in the UK, and none is an authorised food supplement. They are sold to adults for laboratory research and are not for human consumption. Anabolic agents including SARMs are prohibited at all times under the World Anti-Doping Agency (WADA) list, and GW-501516 is listed separately as a metabolic modulator. Tested athletes should treat every compound here as prohibited. Our \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003e2026 SARMs research guide\u003c\/a\u003e goes into more detail.\u003c\/p\u003e\n\u003ch2\u003eDelivery and returns\u003c\/h2\u003e\n\u003cp\u003eFree Muscle is the trading name of FreeMuscle, a business registered in Andorra, with UK operations and dispatch in Scunthorpe. Every order ships free with UK tracking in plain packaging; EU delivery takes 3 to 7 working days. Orders placed before 2pm Monday to Friday are processed the same working day. Unopened items can be returned within 30 days. Details are on our \u003ca href=\"\/en-ro\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages. Customers must be 18 or over.\u003c\/p\u003e\n\u003ch2\u003eRelated reading\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/are-sarms-legal-in-the-uk-2026\"\u003eAre SARMs legal in the UK? 2026 guide: MHRA, FSA, UKAD\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/sarms-explained-how-selective-androgen-receptor-modulators-work-1135-86\"\u003eSARMs Explained: How Selective Androgen Receptor Modulators Work\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/sarms-vs-peptides-choosing-by-goal\"\u003eSARMs vs Peptides: Choosing by Goal\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003ePrice per milligram: the only honest way to compare SARMs and peptides\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003eHow to Read a Certificate of Analysis (COA)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003eRelated collections: \u003ca href=\"\/en-ro\/collections\/mk-677\"\u003eMK-677 (Ibutamoren)\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/pct-blends\"\u003ePCT Blends\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/peptides\"\u003ePeptides\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eBasaria S, et al. The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci. 2013;68(1):87-95. PMID: 22459616.\u003c\/li\u003e\n\u003cli\u003eSolomon ZJ, et al. Selective Androgen Receptor Modulators: Current Knowledge and Clinical Applications. Sex Med Rev. 2019;7(1):84-94. PMID: 30503797.\u003c\/li\u003e\n\u003c\/ol\u003e","products":[{"product_id":"yk-11-10mg","title":"YK-11 — Myostatin Inhibitor · 10mg · 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eYK-11, 10mg × 60 capsules.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eYK-11 is structurally a steroid, not a true SARM, although it is usually sold alongside them. It is sometimes described as a myostatin-pathway agent; that description rests largely on a single cell-culture study and there is no human data.\u003c\/p\u003e\u003cp\u003eBecause it has a steroidal backbone, androgenic and liver effects cannot be ruled out. It is \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e and is prohibited in sport by WADA.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request. We do not publish dosing schedules, cycle lengths or post-cycle protocols for human use.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":46857393144034,"sku":"10000012","price":49.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/yk_11_10mg_60_capsules.jpg?v=1766262356"},{"product_id":"free-muscle-rad-140-testolone-10mg","title":"RAD-140 Testolone — 10mg · 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eRAD-140 (Testolone), 10mg × 60 capsules.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eRAD-140 is a selective androgen receptor modulator. It binds androgen receptors with more selectivity for muscle and bone tissue than anabolic steroids do. Preclinical data exists; human efficacy trials for performance do not.\u003c\/p\u003e\u003cp\u003eSARMs have been associated with liver injury and testosterone suppression in published case reports. RAD-140 is \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e and is on the WADA Prohibited List, where it is detectable in standard screening.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request. We do not publish dosing schedules, cycle lengths or post-cycle protocols for human use.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":46857401336034,"sku":"10000015","price":49.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/openart-image_5GqoU6sK_1760820649070_raw_2e570237-2351-490e-a6a5-64bdfb2fd16d.jpg?v=1766262381"},{"product_id":"cardarine-5mg-free-muscle","title":"Cardarine GW-501516 — 5mg · 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eCardarine (GW-501516), 5mg × 60 capsules.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eCardarine is a PPAR-delta agonist. Clinical development was abandoned after cancers were found at multiple organ sites in animal studies. That is the reason it is not a medicine, and we would rather you knew it before buying than after.\u003c\/p\u003e\u003cp\u003eThere are no completed human efficacy trials. It is \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e and is on the WADA Prohibited List, where it is detectable.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request. We do not publish dosing schedules or cycle lengths for human use.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":46857402613986,"sku":"10000011","price":29.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/openart-image_RQOkrWwu_1760826716832_raw_1.jpg?v=1766262406"},{"product_id":"cardarine-gw-501516-10mg-free-muscle-60-capsules","title":"Cardarine GW-501516 — 10mg · 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eCardarine (GW-501516), 10mg × 60 capsules.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eCardarine is a PPAR-delta agonist. Clinical development was abandoned after cancers were found at multiple organ sites in animal studies. That is the reason it is not a medicine, and we would rather you knew it before buying than after.\u003c\/p\u003e\u003cp\u003eThere are no completed human efficacy trials. It is \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e and is on the WADA Prohibited List, where it is detectable.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request. We do not publish dosing schedules or cycle lengths for human use.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":46857405432034,"sku":"10000010","price":39.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/openart-image_Oef-QDdF_1760826110182_raw_e832e96d-2ef9-42b1-a8b2-c1f787319c72.jpg?v=1766262431"},{"product_id":"rad-150-tlb-150-bioreactive-series","title":"RAD-150 (TLB-150) — Bioreactive Series","description":"\u003cp\u003e\u003cstrong\u003eRAD-150 (TLB-150), Bioreactive Series.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eRAD-150 is a benzoate-ester form of RAD-140 (Testolone), a selective androgen receptor modulator. A benzoate ester generally slows release of the parent compound; that is a chemistry property, not a promised outcome. Neither compound has the clinical data to support a comparison of human results, and we are not going to invent one.\u003c\/p\u003e\u003cp\u003eSARMs have been associated with liver injury and testosterone suppression in published case reports. RAD-150 is \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e and is prohibited in sport by WADA.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":47040801865954,"sku":"10000000","price":69.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/IMG-2551.jpg?v=1766262716"},{"product_id":"imuscle-andarine-s4-60-15mg","title":"iMuscle Andarine S-4 — 60 caps, 15mg","description":"\u003cp\u003eiMuscle Andarine S-4 is supplied as 60 capsules stated at 15 mg each, for a total of 900 mg of andarine per pack. Andarine (S-4) is an early non-steroidal selective androgen receptor modulator whose published evidence comes from animal studies. The product is manufactured by iMuscle and stocked by Free Muscle for laboratory research by adults, with free tracked UK delivery.\u003c\/p\u003e\u003ch2\u003eAbout Andarine (S-4)\u003c\/h2\u003e\u003cp\u003eAndarine, usually written S-4 or S4 and coded GTx-007 during development, is one of the earliest non-steroidal selective androgen receptor modulators. It came from the aryl-propionamide series developed at the University of Tennessee and GTx Inc. in the early 2000s. Like testosterone, it binds and activates the androgen receptor. The series aimed at action on muscle and bone with less effect on other androgen-sensitive tissue; for andarine, that aim was tested only in animals.\u003c\/p\u003e\u003cp\u003eThe published data for S-4 are preclinical. In a 2007 study of 120 female rats, ovariectomised to model accelerated bone loss and treated for 120 days, S-4 maintained whole-body and trabecular bone mineral density and cortical bone content, increased the strength of the femur on mechanical testing and reduced body fat (Kearbey et al., 2007). No controlled human trial of andarine has been published, and the development programme was discontinued. In informal reports the most frequently described effect is a yellow tint to vision and slower adaptation to darkness, attributed in those accounts to the molecule binding in the retina; that finding has not been characterised in a clinical study.\u003c\/p\u003e\u003cp\u003eAndarine has never been approved as a medicine and is named under section S1.2 of the WADA Prohibited List. The animal findings summarised here are not claims about this product.\u003c\/p\u003e\u003ch3\u003eChemical identity\u003c\/h3\u003e\u003cp\u003eThese PubChem identifiers define the substance a certificate for this pack should report. The (2S) marks the molecule's single stereocentre.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystematic name\u003c\/strong\u003e: (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number\u003c\/strong\u003e: 401900-40-1\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormula and molecular weight\u003c\/strong\u003e: C19H18F3N3O6, 441.4 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInChIKey\u003c\/strong\u003e: YVXVTLGIDOACBJ-SFHVURJKSA-N\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePubChem CID\u003c\/strong\u003e: 9824562\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCompound: Andarine (S-4)\u003c\/li\u003e\n\u003cli\u003eBrand: iMuscle\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStated strength: 15 mg per capsule (manufacturer's label claim)\u003c\/li\u003e\n\u003cli\u003eStated total per pack: 900 mg\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThe strength is the manufacturer's label claim; only a batch certificate confirms it. To compare brands of Andarine, use total milligrams per pack, as explained in \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eAndarine in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eBehind searches such as \"andarine UK\", \"S4 SARM UK\" and \"S4 SARM for sale\" sit two questions: can andarine lawfully be bought here, and what makes a listing checkable rather than something taken on trust.\u003c\/p\u003e\u003ch3\u003eThe legal position\u003c\/h3\u003e\u003cp\u003eAndarine is not a licensed medicine in the UK: it has no MHRA marketing authorisation, is not an authorised food supplement, and cannot lawfully be sold for human consumption. Nor is it a controlled drug under the Misuse of Drugs Act 1971. Free Muscle supplies it to adults aged 18 or over for laboratory research only. It is prohibited at all times under section S1 (anabolic agents) of the WADA Prohibited List. Buyers are responsible for the rules that apply to them, including any anti-doping code and, for orders sent to the EU, their own country's import rules. Background on the class is in \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eWhat a checkable listing shows, and how this one measures up\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCheck\u003c\/th\u003e\n\u003cth\u003eThis listing\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eStrength, count and pack total that agree\u003c\/td\u003e\n\u003ctd\u003e15 mg per capsule, 60 capsules, 900 mg per pack\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eManufacturer and seller identified\u003c\/td\u003e\n\u003ctd\u003eMade by iMuscle; sold by FreeMuscle, a business registered in Andorra, and dispatched from Scunthorpe\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCertificate tied to a lot number\u003c\/td\u003e\n\u003ctd\u003eThe manufacturer's COA, where iMuscle supplies one for the batch held (see the certificate section)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTerms of sale\u003c\/td\u003e\n\u003ctd\u003eLaboratory research only, adults aged 18 or over, no instructions for use, no before-and-after images or claims about results\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDelivery\u003c\/td\u003e\n\u003ctd\u003eFree tracked UK delivery in plain packaging; same-working-day processing for orders before 2pm Monday to Friday; EU delivery in 3-7 working days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReturns\u003c\/td\u003e\n\u003ctd\u003eUnopened items within 30 days; see \u003ca href=\"\/en-ro\/pages\/shipping\"\u003edelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eA listing without an amount per capsule fails the first check: it can be neither priced per milligram nor compared with an assay.\u003c\/p\u003e\u003cp\u003eThis matters for andarine in particular. In 2009 anti-doping researchers at the German Sport University Cologne found andarine in oily liquids sold online as green tea extract and face moisturiser, and described the case as the first proof that SARMs were being sold and misused without any clinical approval (Thevis et al., 2009). Only analysis revealed what those bottles held; reviews and Reddit threads about \"S4\" record experiences, not contents. More checks are in \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eThree formats are sold under the andarine name: capsules, liquids and loose powder. Chemically they are identical; they differ in where the quantity per unit gets fixed and in how anyone can verify it. We know of no published comparison of andarine formats.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsules (this product).\u003c\/strong\u003e Powder is blended and filled into shells at manufacture, so the 15 mg per capsule is set before the pot is sealed and a certificate can measure it directly. The limit is uniformity: an assay of pooled capsules reports their average, and variation between capsules shows only if units are tested one by one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquids.\u003c\/strong\u003e Labelled by concentration, so any portion is only as accurate as the volume measured. Solvent evaporating from a bottle opened repeatedly concentrates what remains, and a dissolved compound can come out of solution in the cold, so a certificate describes the liquid only as it was when sampled.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLoose powder.\u003c\/strong\u003e Sold by weight, which places accuracy entirely on the balance and handling of the laboratory using it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInjection.\u003c\/strong\u003e Sometimes asked about by analogy with peptides. Andarine is a small synthetic molecule, not a peptide, so the objection raised against swallowed peptides, breakdown by digestive enzymes, does not apply in the same way (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e). No published human study has given andarine by injection or any other route.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eOn stability, dry powder sealed in a capsule is kept away from the solvents and water in which chemical breakdown usually proceeds fastest. That is a general principle, not a measured result: we know of no published shelf-life data for andarine in any format.\u003c\/p\u003e\u003ch2\u003eAndarine compared with ostarine\u003c\/h2\u003e\u003cp\u003e\"Andarine vs ostarine\" is the comparison searched most often for this compound, and the two are close relatives: aryl-propionamide SARMs from the same GTx programme, built on the same (2S)-2-hydroxy-2-methylpropanamide backbone with a trifluoromethyl group on the anilide ring. They differ in two substituents, and in how far each went in development.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eAndarine (this product)\u003c\/th\u003e\n\u003cth\u003eOstarine\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOther names\u003c\/td\u003e\n\u003ctd\u003eS-4, S4, GTx-007\u003c\/td\u003e\n\u003ctd\u003eMK-2866, enobosarm, GTx-024\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGroup on the anilide ring\u003c\/td\u003e\n\u003ctd\u003eNitro\u003c\/td\u003e\n\u003ctd\u003eCyano\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGroup on the phenoxy ring\u003c\/td\u003e\n\u003ctd\u003eAcetamido\u003c\/td\u003e\n\u003ctd\u003eCyano\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula, molecular weight, CAS\u003c\/td\u003e\n\u003ctd\u003eC19H18F3N3O6, 441.4, 401900-40-1\u003c\/td\u003e\n\u003ctd\u003eC19H14F3N3O3, 389.3, 841205-47-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublished evidence\u003c\/td\u003e\n\u003ctd\u003eRat studies only\u003c\/td\u003e\n\u003ctd\u003ePhase 2 trials in older adults and in people with cancer; phase 3 trials in cancer-related muscle wasting\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAdverse findings in people\u003c\/td\u003e\n\u003ctd\u003eNone from controlled studies; visual changes in informal reports\u003c\/td\u003e\n\u003ctd\u003eAdverse events recorded in monitored trials; named in published reports of liver injury outside them\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLicensed as a medicine\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eS1.2, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eS1.2, prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThe real difference is depth of evidence. Ostarine's trials enrolled people under medical supervision and published what they measured, adverse events included; that record and its limits are set out in \u003ca href=\"\/en-ro\/blogs\/news\/ostarine-mk-2866-research-guide\"\u003eOstarine (MK-2866): the most-studied SARM, what trials found\u003c\/a\u003e. Andarine has no equivalent, so claims that it is \"stronger\" or \"milder\" than ostarine in people rest on anecdote. Milligrams do not translate either: andarine is the heavier molecule, so equal figures on two labels are not equal amounts of substance, and no study establishes any equivalence between them.\u003c\/p\u003e\u003cp\u003eIn law and in sport there is no difference, and both are sold here for laboratory research only. Ostarine brands, including \u003ca href=\"\/en-ro\/products\/imuscle-ostarine-k2866-60-15mg\"\u003eiMuscle Ostarine\u003c\/a\u003e, are compared in the \u003ca href=\"\/en-ro\/collections\/ostarine\"\u003eOstarine (MK-2866) collection\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eiMuscle is a third-party brand, so any certificate of analysis (COA) for this pack is the manufacturer's, not ours. Where iMuscle supplies a COA for the batch we hold, we show it; where none exists for the batch in stock, we say so rather than show a generic document. Free Muscle-brand compounds are assayed batch by batch at Janoshik Analytical; that programme does not cover iMuscle. A real andarine batch certificate should answer each point below.\u003c\/p\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhich compound.\u003c\/strong\u003e Andarine, S-4 or GTx-007, ideally with CAS 401900-40-1. A document headed only \"SARM\" says nothing about this pot.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity, and by what method.\u003c\/strong\u003e HPLC matches the sample's retention time to a reference standard; LC-MS adds a molecular mass that should fit C19H18F3N3O6 (441.4 g\/mol). The 2009 Cologne analysis confirmed identity against reference material by both liquid chromatography and high-resolution mass spectrometry (Thevis et al., 2009).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e Usually an HPLC area percentage: the share of detected material that is andarine. It is the line that would expose a by-product like the one in that 2009 sample, left by poor purification at roughly a tenth of the andarine present. It says nothing about milligrams per capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e The assayed milligrams in a capsule, the figure that tests the 15 mg claim. If it is missing, so is any check on the 900 mg total.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStereochemistry.\u003c\/strong\u003e Andarine is the (2S) form. Its (2R) mirror image has the same formula and mass and is not separated by standard HPLC; only a chiral method tells them apart. A certificate silent on this has not tested for it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLot number, test date and laboratory.\u003c\/strong\u003e The lot on the report has to be the lot on your pot; the test date tells you how old the result is; and the issuing laboratory, if named, can be asked whether the report is genuine.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003eAny blank line means the matching label figure is still unverified; \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e and we will tell you what documentation exists for the stock we hold. See also \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e and our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eAndarine is named in section S1.2 (other anabolic agents) of the WADA Prohibited List and is banned in and out of competition; WADA has prohibited SARMs as a class since 2008 (Thevis et al., 2010). Anti-doping rules apply strict liability: an athlete is responsible for any prohibited substance in their sample, whatever its source, a mislabelled product included.\u003c\/p\u003e\u003cp\u003eTesting does not depend on finding the unchanged molecule. The same Cologne group then characterised andarine's urinary metabolites by liquid chromatography with high-resolution mass spectrometry and confirmed targets for routine doping control: glucuronic acid conjugates of andarine and of its hydroxylated or deacetylated products, a hydrolysis product formed when one of its two aromatic rings is removed, and sulfate conjugates of the hydroxylated and deacetylated metabolites (Thevis et al., 2010).\u003c\/p\u003e\u003cp\u003eWhat the published record does not give is a detection window. We know of no verified study reporting how long andarine or its metabolites remain detectable, so for this product the accurate statement is: detectable, window not established. The absence of a figure is not evidence of a short window. Anyone subject to anti-doping rules should treat any contact with andarine as a risk of an adverse analytical finding.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eWe know of no published stability study of andarine capsules, so the expiry or best-before date printed by iMuscle is the working limit, and a certificate describes the batch as it was on its test date, not as it is now.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eContainer.\u003c\/strong\u003e Leave the capsules in the pot they came in and close it after every opening. Separated from that pot and its lot number, capsules can no longer be matched to a certificate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConditions.\u003c\/strong\u003e A cool, dry cupboard away from direct light and from radiators, ovens and sunny windowsills. Steam from bathrooms and kitchens softens capsule shells and makes powder clump.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRecords.\u003c\/strong\u003e Write the opening date next to the lot number. Any portion taken for analysis needs its own label giving compound, lot and date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChanges in appearance.\u003c\/strong\u003e Capsules that have discoloured, softened or stuck together are no longer the material a certificate describes; set them aside and \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e with the lot number.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHandling and disposal.\u003c\/strong\u003e Wear gloves for opened capsules or powder, work away from food and drink, keep the pot out of reach of children and pets, and dispose of unwanted material as chemical waste under local rules, never in household bins or drains.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator; a non-steroidal ligand of the androgen receptor, pursued in the hope of anabolic action in muscle and bone with less action on the prostate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAndrogen receptor\u003c\/strong\u003e: the protein inside cells that testosterone and dihydrotestosterone activate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAryl-propionamide\u003c\/strong\u003e: the chemical family of andarine, ostarine and S-23, in which a propanamide chain links two substituted benzene rings.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePreclinical\u003c\/strong\u003e: research in cells or animals, before or instead of trials in people.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOvariectomised rat\u003c\/strong\u003e: a female rat with the ovaries removed, a standard model of bone loss after oestrogen deficiency.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBone mineral density\u003c\/strong\u003e: mineral content of bone per unit of area or volume, measured in the 2007 study by dual-energy X-ray absorptiometry.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnantiomers\u003c\/strong\u003e: two mirror-image forms of a molecule with a stereocentre, such as (2S)- and (2R)-andarine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC\u003c\/strong\u003e: high-performance liquid chromatography, which separates a sample's components for identification and measurement against a standard.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLC-MS\u003c\/strong\u003e: liquid chromatography coupled to mass spectrometry, adding each component's mass for a stronger identity check.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolite\u003c\/strong\u003e: a breakdown or conversion product formed in the body; some persist longer than the parent molecule, which is why testers look for them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlucuronide\u003c\/strong\u003e: a metabolite formed when the body attaches glucuronic acid to a molecule, easing its excretion in urine.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eAbout iMuscle Andarine S4\u003c\/h2\u003e\u003cp\u003eThe pot behind this listing is iMuscle's ANDARINE S4: a black screw-top container with an orange wrap-around label and the iMUSCLE logo on a black panel near the cap. A black box at the foot of the label gives 60 capsules at 15 mg each, and the side panel repeats 15 mg per capsule beside the systematic chemical name and a line in which iMuscle states a tested purity above 97%. The brand's Romanian shop lists the product as \"60\/15mg\", its shorthand for capsules per pot over milligrams per capsule, which matches our listing.\u003c\/p\u003e\u003cp\u003eAndarine is one of nine single-compound pots that iMuscle groups as its standard line, and all nine are on our \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle brand page\u003c\/a\u003e. The same pot features in two iMuscle stacks we list, \u003ca href=\"\/en-ro\/products\/imuscle-cardarine-ibutamoren-andarine\"\u003eCardarine, Ibutamoren and Andarine\u003c\/a\u003e and \u003ca href=\"\/en-ro\/products\/imuscle-ostarine-andarine-cardarine\"\u003eOstarine, Andarine and Cardarine\u003c\/a\u003e. As of October 2026 iMuscle is the only andarine maker we carry; the \u003ca href=\"\/en-ro\/collections\/andarine\"\u003eandarine collection\u003c\/a\u003e would show any other brand added later.\u003c\/p\u003e\u003cp\u003eFor context, S-4 comes from the aryl-propionamide group of non-steroidal androgen receptor ligands, and its published record is animal work, with no controlled human trial in print. It holds no UK licence as a medicine, is not a controlled drug, and falls under S1 of the WADA Prohibited List.\u003c\/p\u003e\u003cp\u003eTwo documents appear in the photo gallery. One is a Bulgarian-language test protocol, number RN18684, issued in 2021 by a laboratory in Sofia; it gives iMuscle LTD. as the manufacturer, records an HPLC assay of a single sample, and carries no lot number. The other is an English HPLC print-out for S4 carrying lot 20210910, also from 2021. iMuscle says it sends every lot to an independent European laboratory, yet we have seen no report for the stock now held. Read the lot code on your pot and, if it differs, \u003ca href=\"\/en-ro\/pages\/contact\"\u003eask us\u003c\/a\u003e for whatever the manufacturer supplies for that lot. Janoshik testing covers Free Muscle-brand products only.\u003c\/p\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/andarine\"\u003eAll brands of Andarine (S-4)\u003c\/a\u003e, compared on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/ostarine\"\u003eOstarine (MK-2866)\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/s-23\"\u003eS-23\u003c\/a\u003e and \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eall SARMs\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eKearbey JD, et al. Selective Androgen Receptor Modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats. Pharm Res. 2007;24(2):328-35. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17063395\/\" rel=\"noopener\"\u003ePMID: 17063395\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eThevis M, et al. Detection of the arylpropionamide-derived selective androgen receptor modulator (SARM) S-4 (Andarine) in a black-market product. Drug Test Anal. 2009;1(8):387-92. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20355219\/\" rel=\"noopener\"\u003ePMID: 20355219\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eThevis M, et al. Mass spectrometric characterization of urinary metabolites of the selective androgen receptor modulator andarine (S-4) for routine doping control purposes. Rapid Commun Mass Spectrom. 2010;24(15):2245-54. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20623476\/\" rel=\"noopener\"\u003ePMID: 20623476\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468978893026,"sku":null,"price":30.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/ANDARINES4_720x_7a53b342-6ae9-441a-853c-b0481db9dbc3.jpg?v=1789931395"},{"product_id":"imuscle-cardarine-gw501516-60-10mg","title":"iMuscle Cardarine GW-501516 — 60 caps, 10mg","description":"\u003cp\u003e\u003cstrong\u003eiMuscle Cardarine GW-501516, 60 caps, 10mg\u003c\/strong\u003e is an iMuscle listing of Cardarine, labelled at 10 mg per capsule, 60 capsules per pack, 600 mg in total. It is supplied through the Muscle Market range for laboratory research only, is not for human consumption, and is sold to adults aged 18 and over. Below: what the published research reports, including why development was abandoned, the UK legal position, and how batch certificates are handled for iMuscle products.\u003c\/p\u003e\n\u003ch2\u003eAbout Cardarine\u003c\/h2\u003e\n\u003cp\u003eGW-501516 is the development code; Cardarine, GW501516, GW1516 and endurobol are the other names under which the same molecule is sold. Pharmacologically it is a synthetic PPAR-delta agonist. PPAR-delta is a nuclear receptor, and in skeletal muscle it controls genes that govern how fatty acids are oxidised for energy. GlaxoSmithKline and Ligand took the compound forward as a possible treatment for lipid disorders. Sellers often place it next to SARMs, but it never touches the androgen receptor, and despite occasional searches for \"cardarine peptide\" it is a small molecule of about 454 g\/mol rather than an amino acid chain.\u003c\/p\u003e\n\u003ch3\u003eWhat the published research reports\u003c\/h3\u003e\n\u003cp\u003eIn a 2008 study in mice, GW-501516 combined with treadmill training increased oxidative muscle fibres and running endurance more than training alone, and the authors described PPAR-delta and AMPK agonists as exercise mimetics; in the same paper it was AICAR, a different compound, that raised endurance in untrained mice (Narkar et al., 2008). A GlaxoSmithKline trial published in 2012, in 268 people with low HDL cholesterol, reported that over twelve weeks HDL rose while LDL cholesterol and triglycerides fell from baseline; the trial was short and not designed to assess long-term safety (Olson et al., 2012). Anti-doping researchers later summarised the clinical programme as having reached phase II trials in dyslipidaemia and metabolic syndrome (Thevis et al., 2010).\u003c\/p\u003e\n\u003cp\u003eDevelopment was abandoned in 2007 after two-year carcinogenicity studies in rats and mice found tumours in multiple organs. Those toxicology results were presented at a conference and are not indexed on PubMed, so they are not cited here, but they are the most important fact about this compound. No later human trial has been completed and Cardarine has never been approved as a medicine anywhere. Nothing above is a claim about this product.\u003c\/p\u003e\n\u003ch3\u003eChemical identity\u003c\/h3\u003e\n\u003cp\u003eThese PubChem identifiers describe the molecule a batch certificate for this pack should name.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystematic name\u003c\/strong\u003e: 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number\u003c\/strong\u003e: 317318-70-0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormula and molecular weight\u003c\/strong\u003e: C21H18F3NO3S2, 453.5 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInChIKey\u003c\/strong\u003e: YDBLKRPLXZNVNB-UHFFFAOYSA-N\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePubChem CID\u003c\/strong\u003e: 9803963\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eThis listing\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eManufacturer: iMuscle\u003c\/li\u003e\n\u003cli\u003eCompound: Cardarine (GW-501516)\u003c\/li\u003e\n\u003cli\u003eForm: Capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStrength: 10 mg per capsule, as stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eTotal in pack: 600 mg (10 mg x 60 capsules)\u003c\/li\u003e\n\u003cli\u003eBatch certificate of analysis: shown where iMuscle supplies one for the batch we hold\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption, adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe 10 mg figure is iMuscle's label claim. Only an assay of the batch confirms it. To compare this pack with other Cardarine listings, work from the total milligrams per pack and the cost per milligram, as set out in \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e, and then check what certificate each seller holds.\u003c\/p\u003e\n\u003ch2\u003eCardarine in the UK: buying, legal status and what to check\u003c\/h2\u003e\n\u003cp\u003eSearches such as \"cardarine UK\", \"cardarine UK legal\", \"cardarine UK buy\" and \"cardarine for sale\" come down to two questions: may Cardarine be bought here at all, and how can a buyer tell a listing that can be checked from one that asks to be trusted.\u003c\/p\u003e\n\u003ch3\u003eThe legal position\u003c\/h3\u003e\n\u003cp\u003eCardarine is not a licensed medicine in the UK, has not been assessed by the MHRA, and is not an authorised food supplement, so it cannot lawfully be sold for people to swallow. It is not a controlled drug under the Misuse of Drugs Act 1971. Free Muscle sells it to adults aged 18 and over for laboratory research only, and gives no instructions for use. GW-501516 is named on the WADA Prohibited List under section S4 (hormone and metabolic modulators) as a PPAR-delta agonist and is prohibited at all times in sport. WADA issued a specific warning about it in 2013. Buyers are responsible for the rules that apply to them, including import rules for EU orders. Our \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eresearch guide\u003c\/a\u003e covers the wider legal picture for compounds sold alongside SARMs.\u003c\/p\u003e\n\u003ch3\u003eWhat a checkable UK listing shows\u003c\/h3\u003e\n\u003cp\u003eMany sites file Cardarine under SARMs, but the category label proves nothing. What counts is a short list of verifiable facts, set against this listing below.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eWhat to look for\u003c\/th\u003e\n\u003cth\u003eThis listing\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eA stated strength, a unit count and a pack total that agree\u003c\/td\u003e\n\u003ctd\u003e10 mg per capsule, 60 capsules, 600 mg per pack\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA named manufacturer and a named seller\u003c\/td\u003e\n\u003ctd\u003eMade by iMuscle; sold by FreeMuscle, a business registered in Andorra, and dispatched from Scunthorpe\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA certificate tied to the batch number on the pot\u003c\/td\u003e\n\u003ctd\u003eThe manufacturer's certificate, where iMuscle supplies one for the batch we hold\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eResearch-only terms with no usage directions\u003c\/td\u003e\n\u003ctd\u003eResearch use only, 18+, no amounts, schedules or result claims\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTracked delivery and discreet packaging\u003c\/td\u003e\n\u003ctd\u003eFree tracked UK delivery in plain packaging; orders placed before 2pm Monday to Friday processed the same working day; EU delivery in 3-7 working days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA returns policy\u003c\/td\u003e\n\u003ctd\u003e30-day returns on unopened items, see \u003ca href=\"\/en-ro\/pages\/shipping\"\u003edelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eA listing that promises results, quotes user reviews as evidence or shows before-and-after pictures is advertising a use, which a research supplier cannot lawfully do. The fuller supplier checklist is in \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\n\u003cp\u003eCardarine appears in three physical forms: filled capsules like this pack, liquids sold by concentration, and loose powder sold by weight. The molecule is the same; what differs is where the quantity per unit is fixed and how easily it can be verified. No published study compares these formats for GW-501516.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsules.\u003c\/strong\u003e The 10 mg per capsule is fixed when powder is blended and filled at manufacture, so an assay can measure it directly and the figure cannot drift once the pot is sealed. The weak point is uniformity between individual capsules, which a pooled assay averages out.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquids.\u003c\/strong\u003e Accuracy depends on the concentration being correct and on how precisely a volume is measured. Carrier solvents can evaporate from a bottle that is opened repeatedly, raising the concentration of what is left, and cold storage can cause the compound to crystallise out.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePowder.\u003c\/strong\u003e Accuracy rests entirely on the balance and technique of the laboratory weighing it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBecause Cardarine is a small molecule and not a peptide, the argument that digestive enzymes break down peptides taken by mouth does not apply to it in the same way (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e). On stability, a dry powder sealed in a capsule is kept away from water and solvents, where chemical breakdown generally proceeds fastest, but we know of no published shelf-life study for any Cardarine format.\u003c\/p\u003e\n\u003ch2\u003eCardarine compared with SR9009\u003c\/h2\u003e\n\u003cp\u003e\"Stenabolic vs cardarine\" is the comparison searched most often for this compound, largely because both are sold under metabolic or endurance headings. Pharmacologically they have little in common beyond being synthetic ligands of nuclear receptors.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eCardarine (this product)\u003c\/th\u003e\n\u003cth\u003eSR9009 (stenabolic)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTarget\u003c\/td\u003e\n\u003ctd\u003ePPAR-delta, a fatty acid sensing receptor\u003c\/td\u003e\n\u003ctd\u003eREV-ERB alpha and beta, repressors in the body clock machinery\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eGlaxoSmithKline and Ligand, lipid disorders programme\u003c\/td\u003e\n\u003ctd\u003eAcademic laboratory at the Scripps Research Institute\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and CAS\u003c\/td\u003e\n\u003ctd\u003eC21H18F3NO3S2, 317318-70-0\u003c\/td\u003e\n\u003ctd\u003eC20H24ClN3O4S, 1379686-30-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman data\u003c\/td\u003e\n\u003ctd\u003eShort phase II lipid trials\u003c\/td\u003e\n\u003ctd\u003eNo published human trial\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKey limiting finding\u003c\/td\u003e\n\u003ctd\u003eTumours in two-year rodent studies; development stopped in 2007\u003c\/td\u003e\n\u003ctd\u003eEvidence confined to cells and animals\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLicensed as a medicine\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eS4, metabolic modulator, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eS4, metabolic modulator, prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eSR9009 was first described in 2012, when a Scripps group reported that synthetic REV-ERB agonists altered circadian behaviour and the daily pattern of clock and metabolic gene expression in mice, raised energy expenditure, and reduced fat mass in diet-induced obese mice (Solt et al., 2012). That is a mouse study; no human trial of SR9009 has been published, so its record is shorter than Cardarine's but also lacks Cardarine's two-year toxicology data, which is absence of information rather than reassurance. Cardarine, by contrast, has human lipid data and a carcinogenicity finding that ended its development.\u003c\/p\u003e\n\u003cp\u003eNeither compound is interchangeable with the other, neither is licensed, and both are sold here for laboratory research only. SR9009 listings, including \u003ca href=\"\/en-ro\/products\/imuscle-stenabolic-sr-9009-60-10mg\"\u003eiMuscle Stenabolic SR-9009\u003c\/a\u003e, are compared in the \u003ca href=\"\/en-ro\/collections\/sr9009\"\u003eSR9009 (Stenabolic) collection\u003c\/a\u003e, and the background is in \u003ca href=\"\/en-ro\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 (Stenabolic): the research guide\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\n\u003cp\u003eThe Janoshik Analytical programme that assays every Free Muscle-brand batch, with certificates emailed on request, does not extend to this pack, because iMuscle manufactures it. Any certificate here is iMuscle's own, and we display one only when iMuscle has supplied it for the exact batch on our shelves. We will not pass off an undated or batch-free PDF as a certificate. \u003ca href=\"\/en-ro\/pages\/contact\"\u003eContact us\u003c\/a\u003e with the product name and we will either send the document for current stock or tell you that none exists. Where one is available, these are the lines worth reading.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat was tested.\u003c\/strong\u003e Look for GW-501516 or Cardarine by name, and preferably CAS 317318-70-0. A heading such as \"PPAR agonist\" or \"SARM\" could describe dozens of substances.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow identity was shown.\u003c\/strong\u003e A matching retention time on HPLC against a reference standard is the basic check. Where LC-MS was run, the measured mass ought to fit C21H18F3NO3S2 at 453.5 g\/mol, which is harder to fake or misread.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity figure.\u003c\/strong\u003e Normally a percentage of total peak area on the chromatogram. A high number means few contaminants were seen; it does not reveal the milligram content of a capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMeasured milligrams.\u003c\/strong\u003e An assay result in mg per capsule is what tests iMuscle's 10 mg claim. Without it, the 600 mg pack total rests on the label alone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLot and date.\u003c\/strong\u003e Compare the lot on the report with the lot on the pot; a mismatch means the report describes other stock. The date tells you how long ago the sample was analysed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIssuing laboratory.\u003c\/strong\u003e A named laboratory can be asked to confirm that the report is genuine.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eA missing field is information in itself: whatever the certificate does not measure remains a label claim. Our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests page\u003c\/a\u003e and \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e explain the documents in more detail.\u003c\/p\u003e\n\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\n\u003cp\u003eGW-501516 has been on the WADA Prohibited List since January 2009, when it was first classed as a gene doping agent; it now sits in section S4 among the metabolic modulators and is prohibited in and out of competition (Thevis et al., 2010). Anti-doping rules apply strict liability, so an athlete is responsible for any prohibited substance in a sample regardless of how it got there, including through a mislabelled product.\u003c\/p\u003e\n\u003cp\u003eTesting does not rely on finding the unchanged compound. The Cologne anti-doping laboratory synthesised the two main urinary metabolites, a sulfoxide and a sulfone formed by oxidation of the sulphur atom, confirmed their structures by high-resolution mass spectrometry and NMR, and validated a routine screening method with a reported limit of detection of 0.1 ng\/ml in urine (Thevis et al., 2010). Numerous sanctions have followed.\u003c\/p\u003e\n\u003cp\u003eWe know of no verified published figure for how long Cardarine or its metabolites remain detectable after exposure, so the accurate statement for this product is: detectable, window not established. The lack of a published window is not evidence that the window is short.\u003c\/p\u003e\n\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\n\u003cp\u003eNo published stability study covers Cardarine capsules, so the expiry or best-before date printed by iMuscle is the working limit, and any certificate describes the batch on its test date rather than today.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the original pot.\u003c\/strong\u003e The lot number on the label is what links the capsules to a certificate; capsules moved to another container lose that link.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCool, dry and dark.\u003c\/strong\u003e Store below room temperature where possible, away from radiators and sunny windowsills, and away from bathroom or kitchen humidity, which softens gelatine shells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep a record.\u003c\/strong\u003e Write down when the seal was broken, and give any aliquot sent for analysis its own label carrying the lot number.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCheck condition.\u003c\/strong\u003e If shells have cracked, turned sticky or changed colour, the contents may have changed too; quarantine them and send us the lot number.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory practice.\u003c\/strong\u003e Gloves for any opened capsule, a work area separate from food and drink, storage beyond the reach of children and pets, and disposal through the chemical waste route your local rules set out.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eGlossary\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePPAR-delta\u003c\/strong\u003e: one of three peroxisome proliferator-activated receptors (alpha, gamma and delta); the delta form is widespread in muscle and is the receptor Cardarine binds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eREV-ERB\u003c\/strong\u003e: a pair of nuclear receptors in the circadian clock machinery; the target of SR9009.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExercise mimetic\u003c\/strong\u003e: the description Narkar and colleagues applied in 2008, based on changes in mouse muscle, not on any human finding.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHDL cholesterol\u003c\/strong\u003e: high-density lipoprotein cholesterol, one of the blood lipid measures reported in the human trials.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCarcinogenicity study\u003c\/strong\u003e: a long-term animal study, usually two years in rodents, designed to detect tumour formation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhase II trial\u003c\/strong\u003e: an early human study testing effects on a disease marker in a limited number of participants.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC\u003c\/strong\u003e: a technique that pumps a dissolved sample through a packed column so its components emerge at different times and can be measured.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLC-MS\u003c\/strong\u003e: liquid chromatography coupled to mass spectrometry, which adds a molecular mass to the identity check.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSulfoxide and sulfone\u003c\/strong\u003e: the oxidised forms of GW-501516 found in urine, which anti-doping laboratories screen for.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLimit of detection\u003c\/strong\u003e: the lowest concentration an analytical method can reliably distinguish from zero.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAbout iMuscle Cardarine GW-501516\u003c\/h2\u003e\u003cp\u003eiMuscle prints this pot as CARDARINE on a green label, with GW, 501516 and Endurobol, a marketing name for the compound, in a small line beneath. The iMUSCLE mark sits on black at the top of the label, and a box near the base gives 60 capsules at 10 mg each. A side panel shows 10 mg per capsule, a chemical name and iMuscle's statement that purity tested above 97%. On the brand's Romanian website the same pot appears as Cardarine GW501516, \"60\/10mg\", the figures we list.\u003c\/p\u003e\u003cp\u003eUnlike the other iMuscle singles we stock, this listing has no test document in its gallery, only the pot and its side panel. The 10 mg per capsule, 600 mg per pot, therefore rests on the label until a document for the lot held is produced. iMuscle's quality page says each new batch of raw material goes for testing against a 97% minimum purity; that is the brand's own account, not a result we have seen for this lot. Quote the lot code on the pot when you \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e, and we will say whether iMuscle has supplied anything for it.\u003c\/p\u003e\u003cp\u003eCardarine appears in more iMuscle stacks than any other compound: five of the eight we list include it, from \u003ca href=\"\/en-ro\/products\/imuscle-cardarine-gw501516-ligandrol\"\u003eCardarine and Ligandrol\u003c\/a\u003e to \u003ca href=\"\/en-ro\/products\/imuscle-ostarine-andarine-cardarine\"\u003eOstarine, Andarine and Cardarine\u003c\/a\u003e. Every iMuscle listing is on our \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eGW-501516 is a PPAR-delta agonist rather than a SARM. Its development was stopped after cancers appeared in long-term rodent studies; it has no UK licence and is prohibited by WADA under S4. Among the cardarine brands on our shelves, iMuscle and \u003ca href=\"\/en-ro\/collections\/brand-thoroughbred-labs\"\u003eThoroughbred Labs\u003c\/a\u003e both state 10 mg per capsule in packs of 60, while Free Muscle's own pots come at 5 mg and 10 mg, each batch assayed by Janoshik Analytical. The \u003ca href=\"\/en-ro\/collections\/cardarine\"\u003ecardarine collection\u003c\/a\u003e sets them side by side.\u003c\/p\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eAll brands of Cardarine we stock, compared\u003c\/a\u003e, including \u003ca href=\"\/en-ro\/products\/thoroughbred-labs-gw501516\"\u003eThoroughbred Labs GW-501516\u003c\/a\u003e and our own \u003ca href=\"\/en-ro\/products\/cardarine-gw-501516-10mg-free-muscle-60-capsules\"\u003eFree Muscle Cardarine 10mg\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003eCardarine (GW-501516): why development stopped and what the data show\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/sr9009\"\u003eSR9009 (Stenabolic)\u003c\/a\u003e and \u003ca href=\"\/en-ro\/collections\/weight-loss\"\u003emetabolic support\u003c\/a\u003e collections\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003eBatch testing and certificates of analysis\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice. Summaries of published research describe study findings and are not claims about any product.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eNarkar VA, et al. AMPK and PPARdelta agonists are exercise mimetics. Cell. 2008;134(3):405-15. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18674809\/\" rel=\"noopener\"\u003ePMID: 18674809\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eOlson EJ, et al. Lipid effects of peroxisome proliferator-activated receptor-delta agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Arterioscler Thromb Vasc Biol. 2012;32(9):2289-94. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22814748\/\" rel=\"noopener\"\u003ePMID: 22814748\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eThevis M, et al. Characterization of two major urinary metabolites of the PPARdelta-agonist GW1516 and implementation of the drug in routine doping controls. Anal Bioanal Chem. 2010;396(7):2479-91. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19946680\/\" rel=\"noopener\"\u003ePMID: 19946680\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eSolt LA, et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature. 2012;485(7396):62-8. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22460951\/\" rel=\"noopener\"\u003ePMID: 22460951\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e\n","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468978958562,"sku":null,"price":35.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/CARDARINE2_720x_d6eeb76e-e12e-4d4e-8613-f1d8572b8197.jpg?v=1789931398"},{"product_id":"imuscle-ligandrol-lgd4033-60-8mg","title":"iMuscle Ligandrol LGD-4033 — 60 caps, 8mg","description":"\u003cp\u003eiMuscle Ligandrol LGD-4033 is supplied as 60 capsules stated at 8 mg each, a total of 480 mg of LGD-4033 per pack. LGD-4033, also called ligandrol, is a non-steroidal selective androgen receptor modulator with a placebo-controlled human trial behind it. This iMuscle product is stocked by Free Muscle through Muscle Market for laboratory research by adults only.\u003c\/p\u003e\n\u003ch2\u003eAbout LGD-4033\u003c\/h2\u003e\n\u003cp\u003eLGD-4033, known as ligandrol and, in later development, as VK5211, is a non-steroidal selective androgen receptor modulator developed by Ligand Pharmaceuticals. It binds the androgen receptor with high affinity and was designed to act on muscle and bone while producing less effect on the prostate and skin than testosterone.\u003c\/p\u003e\n\u003cp\u003eIn a placebo-controlled study published in 2013, 76 healthy men aged 21 to 50 received placebo or one of three amounts of LGD-4033 for 21 days (Basaria et al., 2013). Lean body mass rose in a dose-dependent manner, while fat mass did not change significantly. The same study recorded dose-dependent falls in total testosterone, sex hormone-binding globulin, HDL cholesterol and triglycerides; free testosterone and follicle-stimulating hormone fell significantly at the highest amount only. Hormones and lipids returned to baseline after the study ended. Muscle strength and stair-climbing power were also measured, but the abstract reports no functional result, and the authors called for longer trials. Later development did not lead to approval.\u003c\/p\u003e\n\u003cp\u003eOutside clinical trials, the main evidence of harm comes from case reports. In 2020 physicians at Baylor College of Medicine described a 32-year-old man admitted with jaundice, itching and raised liver enzymes after taking a product sold over the counter as Ligandrol for about two weeks (Barbara et al., 2020). A liver biopsy showed cholestatic hepatitis with mild fibrosis, and his blood tests improved once he stopped. The product was never analysed, and the authors noted it may have contained other unapproved drugs. One case cannot show how often such injury occurs, and no long-term human data have been published. Nothing summarised here is a claim about this product.\u003c\/p\u003e\n\u003ch3\u003eChemical identity\u003c\/h3\u003e\n\u003cp\u003ePubChem records LGD-4033 under the identifiers below, which describe the molecule a certificate for this pack should report finding.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystematic name\u003c\/strong\u003e: 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number\u003c\/strong\u003e: 1165910-22-4\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormula and molecular weight\u003c\/strong\u003e: C14H12F6N2O, 338.25 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInChIKey\u003c\/strong\u003e: OPSIVAKKLQRWKC-VXGBXAGGSA-N\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePubChem CID\u003c\/strong\u003e: 44137686\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eThis listing\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCompound: LGD-4033 (Ligandrol)\u003c\/li\u003e\n\u003cli\u003eBrand: iMuscle\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStated strength: 8 mg per capsule (manufacturer's label claim)\u003c\/li\u003e\n\u003cli\u003eStated total per pack: 480 mg\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe strength is the manufacturer's label claim; only a batch certificate confirms it. To compare brands of LGD-4033, use total milligrams per pack, as explained in \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eLGD-4033 in the UK: buying, legal status and what to check\u003c\/h2\u003e\n\u003cp\u003eSearches such as \"LGD 4033 UK buy\" and \"ligandrol UK\" ask two things: whether it can be bought lawfully here, and how to tell one listing from another.\u003c\/p\u003e\n\u003ch3\u003eThe legal position\u003c\/h3\u003e\n\u003cp\u003eLGD-4033 is not a licensed medicine in the UK: it has no MHRA marketing authorisation, is not an authorised food supplement, and cannot lawfully be sold for human consumption. It is not scheduled under the Misuse of Drugs Act, and Free Muscle supplies it only as a research compound, to adults aged 18 or over, for laboratory research. It is prohibited at all times under section S1 (anabolic agents) of the WADA Prohibited List. Buyers are responsible for the rules that apply to them, including any anti-doping code. Background on the class is in \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eWhat a trustworthy listing shows, and where to find it here\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eA strength and a count that multiply.\u003c\/strong\u003e Here, 8 mg by 60 capsules gives the 480 mg stated for the pack; a listing with no strength can be neither compared nor checked.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA named maker and seller.\u003c\/strong\u003e iMuscle manufactures this product; FreeMuscle, a business registered in Andorra, sells it and dispatches it from Scunthorpe.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate for the batch, not the brand.\u003c\/strong\u003e How this works for iMuscle stock is set out in the certificate section below.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-use terms and an age limit.\u003c\/strong\u003e No instructions for use, no outcome claims, adults aged 18 or over only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTracked, discreet delivery.\u003c\/strong\u003e Free tracked UK delivery in plain packaging; orders before 2pm Monday to Friday processed the same working day; EU delivery in 3-7 working days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReturns.\u003c\/strong\u003e Unopened items within 30 days, under our \u003ca href=\"\/en-ro\/pages\/shipping\"\u003edelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e terms.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eA label proves little by itself: the doctors behind the 2020 liver injury report could not say what their patient's \"Ligandrol\" contained, and nor can anyone holding a pot without a batch certificate. Threads under \"ligandrol reddit\" record experiences, not contents. More checks are in \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\n\u003cp\u003eProducts labelled LGD-4033 appear as capsules, tablets, liquids and loose powder. The molecule is the same in each; what differs is how the amount per unit is fixed and how it can be checked. No published study has compared the formats.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsules (this product).\u003c\/strong\u003e A blended powder is portioned into shells at manufacture, so the amount per capsule is fixed then and a certificate can report it directly against the 8 mg claim. Accuracy depends on even mixing, and one assay gives the average of the capsules tested, not the spread between them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTablets.\u003c\/strong\u003e A similar blend compressed with binders, with the same dependence on mixing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquids.\u003c\/strong\u003e Labelled in milligrams per millilitre. A certificate describes the solution on the day of testing; later accuracy depends on drawing exact volumes and on the compound staying dissolved, and solvent lost from a bottle opened often concentrates what remains.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLoose powder.\u003c\/strong\u003e Sold for weighing, which moves the whole question of accuracy onto the balance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSolutions suit very small quantities: the Cologne excretion study described below prepared its microgram amounts from an ethanol solution (Wagener et al., 2022). Because LGD-4033 is a small synthetic molecule rather than a peptide, the usual objection to swallowed peptides, breakdown by digestive enzymes, does not arise in the same way (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e), and the 2013 trial gave it by mouth. We know of no published human study of LGD-4033 given by injection.\u003c\/p\u003e\n\u003ch2\u003eLGD-4033 compared with RAD-140\u003c\/h2\u003e\n\u003cp\u003e\"LGD 4033 vs RAD 140\" and \"ligandrol vs RAD 140\" are the comparisons searched most often for this compound. Both are non-steroidal SARMs that activate the androgen receptor, and both began as drug candidates that never reached approval.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eLGD-4033 (this product)\u003c\/th\u003e\n\u003cth\u003eRAD-140\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOther names\u003c\/td\u003e\n\u003ctd\u003eLigandrol, VK5211\u003c\/td\u003e\n\u003ctd\u003eTestolone, vosilasarm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDeveloper\u003c\/td\u003e\n\u003ctd\u003eLigand Pharmaceuticals, later licensed to Viking Therapeutics\u003c\/td\u003e\n\u003ctd\u003eRadius Health\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eChemical family\u003c\/td\u003e\n\u003ctd\u003ePyrrolidinyl-benzonitrile with six fluorine atoms\u003c\/td\u003e\n\u003ctd\u003eChlorinated benzonitrile with an oxadiazole ring\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula, molecular weight, CAS\u003c\/td\u003e\n\u003ctd\u003eC14H12F6N2O, 338.25, 1165910-22-4\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2, 393.8, 1182367-47-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublished clinical trial\u003c\/td\u003e\n\u003ctd\u003ePlacebo-controlled study in 76 healthy men over 21 days (2013)\u003c\/td\u003e\n\u003ctd\u003ePhase 1 in women with advanced ER-positive, HER2-negative breast cancer (2022)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMain adverse findings in people\u003c\/td\u003e\n\u003ctd\u003eDose-related falls in testosterone, SHBG, HDL cholesterol and triglycerides; a biopsy-confirmed liver injury case\u003c\/td\u003e\n\u003ctd\u003eRaised liver enzymes and bilirubin common in the trial; liver injury case reports\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLicensed as a medicine\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eNamed in S1.2, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eNamed in S1.2, prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe two trials cannot be set side by side. LGD-4033 went to young, screened, healthy men for three weeks, with body composition and hormones among the outcomes; RAD-140 went to women with advanced cancer to find a tolerable amount for oncology, and muscle was not its question. No study has given the two compounds to comparable groups, so claims that one is \"stronger\" or \"milder\" rest on anecdote, and milligrams of two different molecules are no common currency either.\u003c\/p\u003e\n\u003cp\u003eIn law and in sport they stand together, as the last two rows show, and both are sold here for laboratory research only. RAD-140 brands are compared in the \u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 (Testolone) collection\u003c\/a\u003e, and its trial and case reports are covered in \u003ca href=\"\/en-ro\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\n\u003cp\u003eBecause iMuscle is a third-party brand, a certificate of analysis (COA) for this pack is the manufacturer's document, not ours. A certificate is shown only where iMuscle has supplied one for the batch we hold; a generic document that names no batch is not a substitute. Free Muscle-brand compounds are assayed batch by batch at Janoshik Analytical, but that programme does not cover iMuscle. A real batch certificate is specific to one lot. Each part answers a different question, and each gap leaves that question open:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound.\u003c\/strong\u003e It should name LGD-4033 or ligandrol, ideally with the CAS number. A certificate naming only \"SARM\" or another compound does not relate to this pack.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity.\u003c\/strong\u003e HPLC matches the sample's peak to a reference standard; LC-MS adds a molecular mass that should fit C14H12F6N2O. Without identity, a purity figure could describe the wrong substance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIsomer.\u003c\/strong\u003e The (2R) and (1R) in the systematic name mark two stereocentres, so other isomers share the formula and mass. One, the epimer labelled M1, forms in the body and separates from LGD-4033 on chromatography (Wagener et al., 2022); mirror-image forms separate only by chiral methods, so a certificate naming none has not addressed them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e Usually an HPLC area percentage: how much of the detected material is LGD-4033. It says nothing about milligrams per capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e The measured figure to set against 8 mg. Without it, the 480 mg on the label stays untested.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLot, date and laboratory.\u003c\/strong\u003e The lot must match your pot, the date shows the age of the result, and a named laboratory can be asked to confirm it. A different lot describes other stock.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eIf an iMuscle certificate leaves any of these gaps, \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e before relying on the batch. See also \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e and our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\n\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\n\u003cp\u003eLGD-4033 is named in section S1.2 (other anabolic agents) of the WADA Prohibited List and is banned in and out of competition. Under strict liability an athlete answers for any prohibited substance in their sample, whether it came from a research compound, a mislabelled product or a contaminated supplement. WADA reported 62 adverse analytical findings involving LGD-4033 in 2019, a number the Cologne authors described as the highest reported so far (Wagener et al., 2022).\u003c\/p\u003e\n\u003cp\u003eThe most detailed controlled detection data come from microgram amounts. At the German Sport University Cologne, groups of five healthy men took a single 1, 10 or 50 microgram amount, or the same amount on five consecutive days, and their urine was analysed by LC-HRMS\/MS with a limit of detection of 8 picograms per millilitre. After one 50 microgram amount, the longest-lasting metabolite, M5-a, gave its first negative sample only after 11 days. After five daily 50 microgram amounts, metabolite M5-b was still present in every sample when collection ended, 1,004 to 1,128 hours (about 42 to 47 days) after the last intake, so no end point could be set. The authors proposed the ratio of M1 to LGD-4033 for estimating when intake occurred.\u003c\/p\u003e\n\u003cp\u003eNo published study that we can cite establishes a detection window after milligram amounts such as the 8 mg stated per capsule here, so for this product the accurate statement is: detectable, window not established. The microgram results set no upper limit. Anyone subject to anti-doping rules should treat any contact with LGD-4033 as a risk of an adverse finding.\u003c\/p\u003e\n\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\n\u003cp\u003eWe are not aware of any published shelf-life study of LGD-4033 capsules. An expiry or best-before date printed by iMuscle is the limit, and a certificate describes the batch only as it stood on its test date.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eKeep the capsules in their original pot with the lid closed after every opening; the lot number on it is the only link to a certificate.\u003c\/li\u003e\n\u003cli\u003eChoose a cool, dry, dark cupboard away from ovens, radiators, sunny windows and bathrooms. Hard capsule shells soften and stick in damp air and turn brittle in hot, dry air.\u003c\/li\u003e\n\u003cli\u003eIf the pot has been somewhere cold, let it reach room temperature before opening, so condensation does not settle on the capsules.\u003c\/li\u003e\n\u003cli\u003eRecord when the seal was first broken alongside the lot number, and give any portion taken for analysis its own label showing compound, lot and date.\u003c\/li\u003e\n\u003cli\u003eWear gloves with opened capsules or loose powder, keep the material away from food and drink and out of reach of children and pets, and dispose of it as chemical waste, never in household bins or drains.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eReturns are accepted only on unopened items within 30 days, so a pack left sealed until needed keeps its return option.\u003c\/p\u003e\n\u003ch2\u003eGlossary\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAndrogen receptor\u003c\/strong\u003e: the protein inside cells that testosterone switches on; LGD-4033 binds the same receptor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: a non-steroidal ligand of the androgen receptor, developed in the hope of anabolic action in muscle and bone with less action on the prostate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSHBG\u003c\/strong\u003e: sex hormone-binding globulin, the blood protein that carries much circulating testosterone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHDL cholesterol\u003c\/strong\u003e: cholesterol carried in high-density lipoproteins, a standard blood lipid measurement.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhase 1 trial\u003c\/strong\u003e: an early, usually small clinical study of how a compound is tolerated and handled by the body, before any larger trial examines efficacy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCholestatic liver injury\u003c\/strong\u003e: damage that impairs the flow of bile, typically causing jaundice and itching.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStereocentre\u003c\/strong\u003e: an atom whose attached groups can be arranged in two mirror-image ways; LGD-4033 has two.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpimer\u003c\/strong\u003e: an isomer differing from another at only one of several stereocentres.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolite\u003c\/strong\u003e: a substance the body makes from another; anti-doping tests target long-lasting ones.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLimit of detection\u003c\/strong\u003e: the lowest concentration a method can reliably detect.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdverse analytical finding\u003c\/strong\u003e: an anti-doping laboratory's report that a sample contains a prohibited substance, its metabolites or markers of its use; it starts the results-management process rather than concluding it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAbout iMuscle Ligandrol LGD-4033\u003c\/h2\u003e\u003cp\u003eiMuscle's ligandrol comes in a pot labelled LIGANDROL in light blue, with LGD and 4033 printed underneath and the iMUSCLE logo above. At 8 mg per capsule it carries the lowest figure in the brand's single-compound line, where every other pot is labelled 10 or 15 mg. The front box states 60 capsules; the side panel gives 8 mg of Ligandrol LGD 4033 per capsule beside a chemical name and the brand's claim of purity tested above 97%; and the brand's own shop lists it as \"60\/8mg\", 480 mg per pot.\u003c\/p\u003e\u003cp\u003eOn its About page iMuscle calls itself an international online shop for SARMs. Free Muscle stocks its products as a retailer, not as an appointed distributor: we found no iMuscle page naming UK sellers, and we make no claim to official or exclusive status. Ligandrol appears in three iMuscle stacks we list, \u003ca href=\"\/en-ro\/products\/imuscle-cardarine-gw501516-ligandrol\"\u003eCardarine and Ligandrol\u003c\/a\u003e, \u003ca href=\"\/en-ro\/products\/imuscle-ligandrol-ibutamoren-ostarine\"\u003eLigandrol, Ibutamoren and Ostarine\u003c\/a\u003e and \u003ca href=\"\/en-ro\/products\/imuscle-ligandrol-testolon-yk-11\"\u003eLigandrol, Testolon and YK-11\u003c\/a\u003e, and the whole range is on the \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle brand page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eLGD-4033 is a non-steroidal SARM first developed by Ligand Pharmaceuticals; its main human evidence is one short placebo-controlled study in healthy young men. It is unlicensed in the UK and banned under WADA section S1. As of October 2026 no other brand of LGD-4033 is on our shelves; the \u003ca href=\"\/en-ro\/collections\/lgd-4033\"\u003eLGD-4033 collection\u003c\/a\u003e and the \u003ca href=\"\/en-ro\/blogs\/news\/lgd-4033-ligandrol-research-guide\"\u003eligandrol research guide\u003c\/a\u003e cover the compound itself.\u003c\/p\u003e\u003cp\u003eIts gallery shows protocol RN18654 from 2021, recording an HPLC assay of one sample without a lot number, and an HPLC print-out labelled LGD4033 with lot 20210911. Both record a 2021 test rather than the pots on sale now. Check the lot code printed on your pot and \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e with it; we pass on whatever iMuscle supplies for that lot, and Free Muscle's Janoshik programme does not cover this brand.\u003c\/p\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/lgd-4033\"\u003eAll brands of LGD-4033 (Ligandrol)\u003c\/a\u003e, compared on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/blogs\/news\/lgd-4033-ligandrol-research-guide\"\u003eLGD-4033 (ligandrol): trials, findings and UK status\u003c\/a\u003e, the full research guide\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/ostarine\"\u003eOstarine (MK-2866)\u003c\/a\u003e and \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eall SARMs\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eBasaria S, et al. The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci. 2013;68(1):87-95. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22459616\/\" rel=\"noopener\"\u003ePMID: 22459616\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eBarbara M, et al. Ligandrol (LGD-4033)-Induced Liver Injury. ACG Case Rep J. 2020;7(6):e00370. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32637435\/\" rel=\"noopener\"\u003ePMID: 32637435\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eWagener F, et al. Investigations into the elimination profiles and metabolite ratios of micro-dosed selective androgen receptor modulator LGD-4033 for doping control purposes. Anal Bioanal Chem. 2022;414(2):1151-1162. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34734312\/\" rel=\"noopener\"\u003ePMID: 34734312\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468979482850,"sku":null,"price":35.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/LIGANDROL_720x_31d8619e-fb4e-4156-b614-1cc97bde668c.jpg?v=1789931406"},{"product_id":"imuscle-ostarine-k2866-60-15mg","title":"iMuscle Ostarine MK-2866 — 60 caps, 15mg","description":"\u003cp\u003eiMuscle Ostarine MK-2866 is a pack of 60 capsules stated at 15 mg each, 900 mg of ostarine in total. Ostarine, also known as enobosarm, MK-2866 or GTx-024, is the most clinically studied compound in the SARM class, having reached Phase 3 trials without approval. iMuscle manufactures it and Free Muscle stocks it in the Muscle Market range for research use by adults aged 18 and over.\u003c\/p\u003e\u003ch2\u003eAbout Ostarine (MK-2866)\u003c\/h2\u003e\u003cp\u003eOstarine is a non-steroidal selective androgen receptor modulator developed by GTx Inc. for muscle wasting and, later, for breast cancer.\u003c\/p\u003e\u003cp\u003eA 2011 Phase 2 trial in 120 healthy elderly men and postmenopausal women reported a placebo-adjusted increase in lean body mass of about 1.3 kg at the 3 mg dose over 12 weeks, alongside improved stair-climb performance, and also recorded falls in HDL cholesterol and modest suppression of testosterone (Dalton et al., 2011). A 2013 randomised Phase 2 trial in patients with cancer-related muscle wasting again found increases in lean body mass (Dobs et al., 2013), but the subsequent Phase 3 POWER trials did not meet their co-primary endpoints and enobosarm was not approved. It remains unlicensed as a medicine in every country.\u003c\/p\u003e\u003cp\u003eThe adverse findings carry as much weight as the lean mass figure. In the full 2011 report, HDL cholesterol fell with dose, by 27 per cent at the highest dose; in men, SHBG and total testosterone fell, though free testosterone did not change significantly; and eight participants had transient rises in the liver enzyme ALT, one of whom was withdrawn. Outside trials, physicians at the University of British Columbia described a previously healthy man in his early forties admitted with jaundice after two months of taking ostarine bought online, without medical supervision (Bedi et al., 2021). A liver biopsy showed moderate to severe cholestasis consistent with drug-induced liver injury, and his blood tests improved gradually over the following months. He had also been taking two prescribed medicines, and the report describes no analysis of the product. One case cannot show how often such injury occurs, and no long-term human data exist.\u003c\/p\u003e\u003cp\u003eThe findings above describe the compound in clinical research and case reports and are not claims about this listing. The later breast cancer trial and the wider literature are covered in the \u003ca href=\"\/en-ro\/blogs\/news\/ostarine-mk-2866-research-guide\"\u003eostarine research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCompound: Ostarine (MK-2866)\u003c\/li\u003e\n\u003cli\u003eBrand: iMuscle\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStated strength: 15 mg per capsule (manufacturer's label claim)\u003c\/li\u003e\n\u003cli\u003eStated total per pack: 900 mg\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThe strength is the manufacturer's label claim; only a batch certificate confirms it. To compare brands of Ostarine, use total milligrams per pack, as explained in \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eOstarine in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eBehind \"ostarine UK\", \"MK 2866 buy UK\" and \"ostarine UK sale\" sit two questions: is buying it here lawful, and what separates one listing from another?\u003c\/p\u003e\u003ch3\u003eThe legal position\u003c\/h3\u003e\u003cp\u003eOstarine is not a licensed medicine in the UK: it has no MHRA marketing authorisation, is not an authorised food supplement, and cannot lawfully be sold for human consumption. It is not a controlled drug under the Misuse of Drugs Act 1971, and Free Muscle supplies it to adults aged 18 or over for laboratory research only. It is prohibited at all times under section S1 (anabolic agents) of the WADA Prohibited List. Buyers are responsible for the rules that apply to them, including any anti-doping code. Background on the class is in \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eSix things a UK listing should show\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLabel figures that can be tested.\u003c\/strong\u003e A strength per capsule and a count, as listed above; without them a listing can be neither checked nor compared.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWho makes it and who sells it.\u003c\/strong\u003e The manufacturer is iMuscle; the seller is FreeMuscle, a business registered in Andorra with UK operations and dispatch in Scunthorpe.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA lot number that leads to a certificate.\u003c\/strong\u003e The number printed on the pot ties the capsules to an analysis; how this works for iMuscle stock is set out in the certificate section below.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSold for research, to adults.\u003c\/strong\u003e The page gives no directions for use and promises nothing about outcomes, and every buyer must be 18 or over.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDelivery that can be followed.\u003c\/strong\u003e Every UK order travels free, tracked and in plain packaging; orders placed before 2pm Monday to Friday are processed the same working day, and EU delivery takes 3-7 working days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA way back.\u003c\/strong\u003e Unopened items can be returned within 30 days, on the terms given on our \u003ca href=\"\/en-ro\/pages\/shipping\"\u003edelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eReviews and \"ostarine UK reddit\" threads can say how fast a parcel arrived, not what the capsules contained; only a laboratory can say that. A longer checklist is in \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003e\"Ostarine tablets UK\", \"ostarine capsules UK\" and \"ostarine liquid UK\" are all searched. Ostarine is a small synthetic molecule with a molecular weight of 389.3, not a peptide, so the usual objection to swallowed peptides, breakdown by digestive enzymes, does not apply in the same way (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e); the Cologne excretion study described below gave it by mouth. The forms differ in how the amount per unit is fixed and how far a certificate can confirm it; no published study has compared them.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eHow the amount is set\u003c\/th\u003e\n\u003cth\u003eWhat a certificate can confirm\u003c\/th\u003e\n\u003cth\u003eMain weakness\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCapsules (this product)\u003c\/td\u003e\n\u003ctd\u003eA powder blend is filled into shells at manufacture\u003c\/td\u003e\n\u003ctd\u003eMeasured content per capsule against the 15 mg label figure\u003c\/td\u003e\n\u003ctd\u003eUniformity between capsules depends on how well the blend was mixed, which an assay of pooled capsules does not reveal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTablets\u003c\/td\u003e\n\u003ctd\u003eA blend is compressed with binders and fillers\u003c\/td\u003e\n\u003ctd\u003eContent per tablet\u003c\/td\u003e\n\u003ctd\u003eThe same reliance on mixing, plus uneven content if tablets are split\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLiquids\u003c\/td\u003e\n\u003ctd\u003eDissolved to a stated concentration in milligrams per millilitre\u003c\/td\u003e\n\u003ctd\u003eConcentration of the solution on the day it was tested\u003c\/td\u003e\n\u003ctd\u003eThe quantity per millilitre can drift after testing, through inaccurate measuring, the compound coming out of solution, or evaporation from a bottle opened repeatedly\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLoose powder\u003c\/td\u003e\n\u003ctd\u003eNot portioned at all\u003c\/td\u003e\n\u003ctd\u003eIdentity and purity of the powder\u003c\/td\u003e\n\u003ctd\u003eEvery quantity must be weighed, so accuracy rests on the balance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eNone of this is a claim that one form works better than another; it concerns only how a stated quantity can be verified.\u003c\/p\u003e\u003ch2\u003eOstarine compared with LGD-4033\u003c\/h2\u003e\u003cp\u003e\"Ligandrol vs ostarine\" sets ostarine against another member of its class; \"MK 2866 vs MK 677\", a pairing with an unrelated growth hormone secretagogue, is answered in the questions below. Ostarine and LGD-4033 are both non-steroidal SARMs that activate the androgen receptor, and both began as drug candidates that were never approved.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eOstarine (this product)\u003c\/th\u003e\n\u003cth\u003eLGD-4033\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOther names\u003c\/td\u003e\n\u003ctd\u003eEnobosarm, MK-2866, GTx-024\u003c\/td\u003e\n\u003ctd\u003eLigandrol, VK5211\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOriginator\u003c\/td\u003e\n\u003ctd\u003eGTx Inc.\u003c\/td\u003e\n\u003ctd\u003eLigand Pharmaceuticals\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eChemical family\u003c\/td\u003e\n\u003ctd\u003eAryl-propionamide with one stereocentre, the (2S) form\u003c\/td\u003e\n\u003ctd\u003ePyrrolidinyl-benzonitrile with two stereocentres\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and molecular weight\u003c\/td\u003e\n\u003ctd\u003eC19H14F3N3O3, 389.3\u003c\/td\u003e\n\u003ctd\u003eC14H12F6N2O, 338.25\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e841205-47-8\u003c\/td\u003e\n\u003ctd\u003e1165910-22-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFurthest clinical stage\u003c\/td\u003e\n\u003ctd\u003ePhase 3 (the POWER trials in cancer-related muscle wasting)\u003c\/td\u003e\n\u003ctd\u003ePhase 1: one placebo-controlled trial in 76 healthy men aged 21 to 50, lasting 21 days (2013)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAdverse findings reported in people\u003c\/td\u003e\n\u003ctd\u003eFalls in HDL cholesterol, SHBG and total testosterone; transient ALT rises; a biopsy-proven case of cholestatic liver injury\u003c\/td\u003e\n\u003ctd\u003eTotal testosterone, SHBG, HDL cholesterol and triglycerides fell as the dose rose; one biopsy-confirmed report of cholestatic liver injury\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLicensed as a medicine\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eS1.2, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eS1.2, prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThe table invites a head-to-head reading the evidence cannot support. Ostarine's Phase 2 trials enrolled older adults and people with cancer over roughly twelve to sixteen weeks; the only LGD-4033 trial enrolled young, healthy men for three weeks. No study has given both compounds to comparable participants, so any ranking by strength or tolerability has no trial behind it, and a milligram of one molecule is not equivalent to a milligram of the other.\u003c\/p\u003e\u003cp\u003eWhat they share is status: unlicensed everywhere, sold here for laboratory research only, and prohibited under the same WADA section. Brands of LGD-4033 are compared in the \u003ca href=\"\/en-ro\/collections\/lgd-4033\"\u003eLGD-4033 (Ligandrol) collection\u003c\/a\u003e, and its trial is summarised in \u003ca href=\"\/en-ro\/blogs\/news\/lgd-4033-ligandrol-research-guide\"\u003eLGD-4033 (ligandrol): trials, findings and UK status\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eiMuscle is a third-party brand, so any certificate of analysis (COA) for this pack is the manufacturer's, not ours. Where iMuscle supplies a COA for the batch we hold, we show it; where none exists for the batch in stock, we say so rather than show a generic document. Free Muscle-brand compounds are assayed batch by batch at Janoshik Analytical; that programme does not cover iMuscle. When a certificate is available, check each field against the table.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eField\u003c\/th\u003e\n\u003cth\u003eWhat it should show for this product\u003c\/th\u003e\n\u003cth\u003eWhat a gap means\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCompound\u003c\/td\u003e\n\u003ctd\u003eOstarine, enobosarm or MK-2866, ideally with CAS 841205-47-8\u003c\/td\u003e\n\u003ctd\u003eIt does not describe this pot\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIdentity\u003c\/td\u003e\n\u003ctd\u003eHPLC against a reference standard, or LC-MS showing a mass consistent with C19H14F3N3O3 (molecular weight 389.3)\u003c\/td\u003e\n\u003ctd\u003eWithout identity, a purity figure could belong to a different substance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStereochemistry\u003c\/td\u003e\n\u003ctd\u003eThe (2S) form that PubChem records under InChIKey JNGVJMBLXIUVRD-SFHVURJKSA-N\u003c\/td\u003e\n\u003ctd\u003eIts mirror image has the same mass and is resolved only by a chiral method, so a certificate naming none has not addressed it\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003eA percentage, usually from HPLC peak area\u003c\/td\u003e\n\u003ctd\u003eNothing is known about impurities or breakdown products\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eContent per capsule\u003c\/td\u003e\n\u003ctd\u003eA measured figure in milligrams to set against the 15 mg label claim\u003c\/td\u003e\n\u003ctd\u003eThe 900 mg per pack stays an untested label claim\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBatch number\u003c\/td\u003e\n\u003ctd\u003eThe same lot as printed on your pot\u003c\/td\u003e\n\u003ctd\u003eThe certificate describes other stock\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTest date and laboratory\u003c\/td\u003e\n\u003ctd\u003eA date and a named laboratory that can confirm the report\u003c\/td\u003e\n\u003ctd\u003eThe result cannot be traced\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eWhere a field is blank on the certificate for our current batch, ask us through the \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact page\u003c\/a\u003e what is known before relying on that batch. Further detail is in \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e and on our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eOstarine is named in section S1.2 (other anabolic agents) of the WADA Prohibited List, banned in and out of competition, and is the SARM most frequently detected in anti-doping analyses. Under strict liability an athlete answers for any prohibited substance in their sample, whatever its source, and supplements contaminated with minute amounts of ostarine have become a major concern for athletes and the authorities that manage results.\u003c\/p\u003e\u003cp\u003eThat concern prompted a controlled study at the German Sport University Cologne, where single and repeated oral amounts of 1, 10 and 50 micrograms of ostarine were given and urine was analysed by LC-MS\/MS (Walpurgis et al., 2020). A single 1 microgram amount could be detected for up to nine days, depending on whether ostarine itself or its glucuronide was the target, while hydroxylated metabolites gave considerably shorter windows. Peak urine levels and detection times rose with the amount given and varied widely between individuals.\u003c\/p\u003e\u003cp\u003eNo verified study we can cite gives a detection window after milligram quantities such as the 15 mg stated per capsule here, so the accurate statement for this product is: detectable, window not established. Because detection time increased with the amount, the microgram figures are not an upper limit. Anyone subject to an anti-doping code should treat any contact with ostarine as a risk of an adverse finding.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eWe can cite no published stability study of ostarine capsules, so we quote no shelf life. Work to the expiry date on the iMuscle pot; a certificate reflects the batch only on its test date.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eContainer.\u003c\/strong\u003e Keep the capsules in the original pot, closed fully after each opening; the pot carries the lot number, and decanting into an unlabelled container breaks the link to any certificate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConditions.\u003c\/strong\u003e A cool, dry, dark place away from heat and direct sunlight. Kitchens and bathrooms are poor choices, as capsule shells take up moisture and can soften or stick together.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRecords.\u003c\/strong\u003e Note the lot number and the date the seal was broken, and label any sample taken for analysis with compound, lot and date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHandling.\u003c\/strong\u003e Use gloves with opened capsules or loose powder, keep the material away from food and drink and out of reach of children and pets, and dispose of it as chemical waste rather than in household bins or drains.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eBreaking the seal also ends the 30-day return option, which applies to unopened items only.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnobosarm\u003c\/strong\u003e: the International Nonproprietary Name for ostarine, used in clinical publications; MK-2866 and GTx-024 are development codes for the same molecule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSelective androgen receptor modulator (SARM)\u003c\/strong\u003e: a non-steroidal androgen receptor activator whose developers aimed for effects on muscle and bone with less action on the prostate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAryl-propionamide\u003c\/strong\u003e: the chemical family ostarine belongs to, which also includes andarine (S-4) and S-23.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLean body mass\u003c\/strong\u003e: body weight minus fat, measured in the ostarine trials by dual-energy X-ray absorptiometry (DXA); it includes water and organs as well as muscle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCo-primary endpoint\u003c\/strong\u003e: one of the main outcomes, set in advance, that a trial must meet to count as a success; the POWER trials fell short on theirs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSHBG\u003c\/strong\u003e: sex hormone-binding globulin, which binds testosterone in the blood, so total testosterone tends to fall when SHBG does.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eALT\u003c\/strong\u003e: alanine aminotransferase, a liver enzyme whose blood level rises when liver cells are damaged.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCholestasis\u003c\/strong\u003e: reduced flow of bile from the liver, which can cause jaundice; the pattern seen in the ostarine case report.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlucuronide\u003c\/strong\u003e: a compound joined to glucuronic acid by the body so it can be excreted in urine; anti-doping methods can target it.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eAbout iMuscle Ostabolon (Ostarine MK-2866)\u003c\/h2\u003e\u003cp\u003eAnyone searching for iMuscle ostarine will find the word OSTABOLON on the pot rather than ostarine: it is iMuscle's own trade name, printed large on a yellow label, with MK, 2866 and OSTARINE in a smaller line to identify the compound. The front box gives 60 capsules at 15 mg each, the side panel 15 mg of Ostarine MK 2866 per capsule with a chemical name and the brand's above-97% purity statement, and on imuscle.ro the product appears as Ostarine MK2866, \"60\/15mg\". Our listing carries the same figures, 900 mg per pot.\u003c\/p\u003e\u003cp\u003eOstabolon is one of the nine single pots in iMuscle's standard line, which its About page sets apart from a combined series of multi-compound capsules sold as VENOM, HULKED, COMBAT and MACHINE. We stock the nine singles and eight stacks, not the combined series. This pot is in three of those stacks: \u003ca href=\"\/en-ro\/products\/imuscle-cardarine-ostarine-mk2866\"\u003eCardarine and Ostarine\u003c\/a\u003e, \u003ca href=\"\/en-ro\/products\/imuscle-ostarine-andarine-cardarine\"\u003eOstarine, Andarine and Cardarine\u003c\/a\u003e and \u003ca href=\"\/en-ro\/products\/imuscle-ligandrol-ibutamoren-ostarine\"\u003eLigandrol, Ibutamoren and Ostarine\u003c\/a\u003e. Every listing is on the \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eOf the compounds sold as SARMs, enobosarm went furthest in clinical work, reaching phase 3 trials in cancer-related muscle loss without approval anywhere; it has no UK licence and WADA lists it under S1. iMuscle is the only ostarine brand we stock as of October 2026, and the \u003ca href=\"\/en-ro\/collections\/ostarine\"\u003eostarine collection\u003c\/a\u003e will reflect any change.\u003c\/p\u003e\u003cp\u003eThe test protocol in the gallery, RN18634, and the English HPLC print-out for MK2866 with lot 20210908 both date from 2021, and the protocol has no lot number of its own. iMuscle states that every lot is checked at an independent European laboratory; we have not seen a report for the stock held now. Compare the lot code on your pot with any document, and \u003ca href=\"\/en-ro\/pages\/contact\"\u003eask us\u003c\/a\u003e with that code before relying on a figure.\u003c\/p\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/ostarine\"\u003eAll brands of Ostarine (MK-2866)\u003c\/a\u003e, compared on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/ostarine-mk-2866-research-guide\"\u003eOstarine (MK-2866): the most-studied SARM, what trials found\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/lgd-4033\"\u003eLGD-4033 (Ligandrol)\u003c\/a\u003e and \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eall SARMs\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eDalton JT, et al. The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial. J Cachexia Sarcopenia Muscle. 2011;2(3):153-161. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22031847\/\" rel=\"noopener\"\u003ePMID: 22031847\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eDobs AS, et al. Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial. Lancet Oncol. 2013;14(4):335-45. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23499390\/\" rel=\"noopener\"\u003ePMID: 23499390\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eBedi H, et al. Drug-Induced Liver Injury From Enobosarm (Ostarine), a Selective Androgen Receptor Modulator. ACG Case Rep J. 2021;8(1):e00518. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34368386\/\" rel=\"noopener\"\u003ePMID: 34368386\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eWalpurgis K, et al. Elimination profiles of microdosed ostarine mimicking contaminated products ingestion. Drug Test Anal. 2020;12(11-12):1570-1580. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32959982\/\" rel=\"noopener\"\u003ePMID: 32959982\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468980039906,"sku":null,"price":33.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/OSTABOLON_720x_038c6b35-a391-48d6-a65a-43cf847f030f.jpg?v=1789931412"},{"product_id":"imuscle-s-23-60-15mg","title":"iMuscle S-23 — 60 caps, 15mg","description":"\u003cp\u003eiMuscle S-23 is a pack of 60 capsules stated at 15 mg each, 900 mg of S-23 in total. S-23 is a potent non-steroidal selective androgen receptor modulator that was studied in rats as a candidate for hormonal male contraception. It has never been tested in a published clinical trial; the only human data come from anti-doping excretion studies. Free Muscle stocks this iMuscle product through Muscle Market for laboratory research by adults aged 18 and over.\u003c\/p\u003e\u003ch2\u003eAbout S-23\u003c\/h2\u003e\u003cp\u003eS-23 is a non-steroidal selective androgen receptor modulator from the same aryl-propionamide family as andarine and ostarine. It was investigated not for muscle wasting but as a candidate for hormonal male contraception, because of how effectively it suppressed the pituitary-gonadal axis in animals.\u003c\/p\u003e\u003cp\u003eThe key paper is a 2009 preclinical characterisation in rats (Jones et al., 2009). S-23 bound the androgen receptor with an inhibitory constant of about 1.7 nanomolar and behaved as a full agonist in cell assays. In the animals it increased levator ani muscle weight and, when combined with an oestrogen, suppressed spermatogenesis and produced infertility that reversed once treatment stopped. The same work recorded a strong decrease in luteinising hormone and follicle-stimulating hormone. In castrated rats it acted on the prostate as well as on muscle, though at higher amounts, while in intact rats prostate size fell as luteinising hormone was suppressed. No clinical trial of S-23 has been published, and no clinical development has been reported. Its suppressive effect on the animals' own reproductive hormones is therefore its best-documented property. These rodent findings are not claims about this listing.\u003c\/p\u003e\u003ch3\u003eName and chemical identity\u003c\/h3\u003e\u003cp\u003eS-23 never reached clinical development, so it is known only by its series code, also written S23, and is easily confused with S-22 (an early code for ostarine) and S-4 (andarine). A certificate for this pack should match these PubChem identifiers:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystematic name\u003c\/strong\u003e: (2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number\u003c\/strong\u003e: 1010396-29-8\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormula and molecular weight\u003c\/strong\u003e: C18H13ClF4N2O3, 416.8 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInChIKey\u003c\/strong\u003e: SSFVOEAXHZGTRJ-KRWDZBQOSA-N\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePubChem CID\u003c\/strong\u003e: 24892822\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCompound: S-23\u003c\/li\u003e\n\u003cli\u003eBrand: iMuscle\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStated strength: 15 mg per capsule (manufacturer's label claim)\u003c\/li\u003e\n\u003cli\u003eStated total per pack: 900 mg\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThe strength is the manufacturer's label claim; only a batch certificate confirms it. To compare brands of S-23, use total milligrams per pack, as explained in \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eS-23 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"S23 SARM UK\" and \"S-23 SARM for sale\" ask two things: whether S-23 can be bought lawfully in Britain, and how to tell a listing that can be checked from one that must be taken on trust.\u003c\/p\u003e\u003ch3\u003eThe legal position\u003c\/h3\u003e\u003cp\u003eS-23 is not a licensed medicine in the UK: it has no MHRA marketing authorisation, and no regulator anywhere has granted one. Nor is it an authorised food supplement, so it cannot lawfully be sold for human consumption, although it is not a controlled substance. Free Muscle supplies it to adults aged 18 or over for laboratory research only. WADA prohibits it at all times under section S1 (anabolic agents) of its Prohibited List. Buyers are responsible for the rules that bind them, including any anti-doping code and, for EU orders, local import rules. The wider class is covered in \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eWhat a listing should show, and what this one shows\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCheck\u003c\/th\u003e\n\u003cth\u003eWhy it matters for S-23\u003c\/th\u003e\n\u003cth\u003eThis listing\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCompound named precisely\u003c\/td\u003e\n\u003ctd\u003eA certificate can only be matched to an exact name\u003c\/td\u003e\n\u003ctd\u003eS-23, with the identifiers above\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStrength and capsule count\u003c\/td\u003e\n\u003ctd\u003eNeeded for a pack total and a price per milligram\u003c\/td\u003e\n\u003ctd\u003e15 mg by 60 capsules, 900 mg per pack (label claim)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCertificate for the batch sold\u003c\/td\u003e\n\u003ctd\u003eThe only evidence of what the capsules contain\u003c\/td\u003e\n\u003ctd\u003eShown only where iMuscle supplies one for the batch we hold; otherwise we say none exists\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA named seller\u003c\/td\u003e\n\u003ctd\u003eSomeone accountable for the sale\u003c\/td\u003e\n\u003ctd\u003eFreeMuscle, a business registered in Andorra, with UK operations and dispatch in Scunthorpe\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eResearch-only terms\u003c\/td\u003e\n\u003ctd\u003eDirections or promised results signal a sale for consumption\u003c\/td\u003e\n\u003ctd\u003eLaboratory research, adults 18+, no directions or outcome claims\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDelivery and returns\u003c\/td\u003e\n\u003ctd\u003eShows who holds the parcel, and on what terms\u003c\/td\u003e\n\u003ctd\u003eFree tracked UK delivery on every order, in plain packaging; same-day processing for orders before 2pm Monday to Friday; EU delivery in 3-7 working days; unopened items returnable within 30 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eA label alone proves little. Anti-doping researchers in Cologne name contaminated dietary supplements as one route by which SARMs have reached athletes' samples (Alhalabi et al., 2025): a tub can carry a substance it does not declare. Reviews of \"S23\" record what writers felt, not what they took. Full terms are on our \u003ca href=\"\/en-ro\/pages\/shipping\"\u003edelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages, and further checks are in \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eBesides capsules, S-23 circulates as tablets and as liquids labelled in milligrams per millilitre. The molecule does not change between them; what changes is where the stated amount is fixed and what a certificate can confirm. No published study has compared formats of S-23.\u003c\/p\u003e\u003cp\u003eIn a capsule or tablet the amount per unit is fixed at the factory, so a laboratory can report milligrams per capsule, the figure that tests the 15 mg claim here, although a pooled assay gives only the average and unit-to-unit variation shows only when capsules are tested singly. A liquid's certificate reports concentration on the test date, and the amount in any portion then depends on how accurately a volume is drawn, whether the compound stays dissolved in the cold, and solvent lost from a bottle opened many times.\u003c\/p\u003e\u003cp\u003eAs a small synthetic molecule rather than a peptide, S-23 is not open in the same way to the objection that digestive enzymes break swallowed peptides apart (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e). The oral excretion studies described under detection below gave it by mouth, one as a tablet, and we know of no published study of it by injection. A dry powder in a shell is also kept from the water and solvents in which breakdown usually runs fastest, though that is general chemistry, not a measured result for S-23.\u003c\/p\u003e\u003ch2\u003eS-23 compared with RAD-140\u003c\/h2\u003e\u003cp\u003e\"S23 vs RAD140\" is the comparison searched most often for this compound, usually as a question about which is stronger. Chemistry and regulation answer part of it; the rest has never been studied.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eS-23 (this product)\u003c\/th\u003e\n\u003cth\u003eRAD-140\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eChemical family\u003c\/td\u003e\n\u003ctd\u003eAryl-propionamide, like andarine and ostarine\u003c\/td\u003e\n\u003ctd\u003eA different scaffold built around a 1,3,4-oxadiazole ring\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula, molecular weight, CAS\u003c\/td\u003e\n\u003ctd\u003eC18H13ClF4N2O3, 416.8, 1010396-29-8\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2, 393.8, 1182367-47-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurpose of the research\u003c\/td\u003e\n\u003ctd\u003eHormonal male contraception, in rats (2009)\u003c\/td\u003e\n\u003ctd\u003eAnabolic androgen action in preclinical models (Radius Health, 2011); later breast cancer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStudies in people\u003c\/td\u003e\n\u003ctd\u003eNo clinical trial; anti-doping excretion studies only\u003c\/td\u003e\n\u003ctd\u003eOne Phase 1 trial in 22 women with advanced breast cancer; anti-doping excretion studies\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBest-documented effects\u003c\/td\u003e\n\u003ctd\u003eStrong LH and FSH suppression; with an oestrogen, reversible loss of sperm production (rats)\u003c\/td\u003e\n\u003ctd\u003eRaised AST, ALT and bilirubin, the most frequent adverse events in that trial (LoRusso et al., 2022)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLicensed as a medicine\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eS1.2, prohibited as a SARM\u003c\/td\u003e\n\u003ctd\u003eS1.2, named among the examples\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eS-23's reputation for strength rests on the 2009 cell work, where it bound the receptor tightly and switched it on fully; Radius Health likewise called RAD-140 potent. Those results come from different laboratories, assays and species, and no study has tested the two side by side, so no ranking is supported. Receptor potency would in any case say nothing about effects or risks in a person.\u003c\/p\u003e\u003cp\u003eThe evidence is unequal: RAD-140 has adverse events and blood levels recorded in supervised patients, while S-23 has rat pharmacology and urine data from anti-doping volunteers. No equivalence between their milligram labels has been established, and both are sold here for laboratory research only. RAD-140 brands, including \u003ca href=\"\/en-ro\/products\/imuscle-testolon-rad-140-60-10mg\"\u003eiMuscle Testolone RAD-140\u003c\/a\u003e, are compared in the \u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 (Testolone) collection\u003c\/a\u003e, and its research record is set out in \u003ca href=\"\/en-ro\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eiMuscle is a third-party brand, so any certificate of analysis (COA) is the manufacturer's, not ours. Where iMuscle has supplied one for the batch we hold, we show it; where none exists, we say so rather than show a generic document. Our Janoshik Analytical batch testing covers Free Muscle-brand compounds only, not iMuscle. At a minimum, a real batch certificate carries the lot number printed on the pack, the test method (HPLC or LC-MS) and a purity figure; a full S-23 certificate lets you check each of these:\u003c\/p\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe right compound.\u003c\/strong\u003e S-23 by name, ideally with CAS 1010396-29-8. A report for S-22, S-4 or an unnamed \"SARM\" does not describe this pot.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity, with the method stated.\u003c\/strong\u003e HPLC matches a peak to an S-23 reference standard; LC-MS adds a mass that should fit C18H13ClF4N2O3 (416.8 g\/mol). With one chlorine atom, S-23 should also give a companion signal two mass units higher, roughly a third the height of the main one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e The percentage of chromatogram peak area that is S-23. A high figure says the material is clean, not that each capsule holds 15 mg.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e A measured milligram figure to set against the 15 mg label claim; sixty times it is the real pack total.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhich mirror-image form.\u003c\/strong\u003e S-23 is the (2S) form. Its mirror image has the same formula and mass, which ordinary HPLC and LC-MS cannot tell apart; unless a chiral method is named, this has not been checked.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLot number, test date and laboratory.\u003c\/strong\u003e The lot must match your pot; the date shows the result's age; a named laboratory can confirm it issued the report.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003eIf an iMuscle document falls short on any of these, \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e with your lot number and we will tell you what exists for the stock we hold. See also \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e and our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eS-23 falls under section S1.2 (other anabolic agents) of the WADA Prohibited List, which covers SARMs as a class, and is banned in and out of competition. It lay behind five adverse analytical findings reported in 2022 (Alhalabi et al., 2025), and under strict liability an athlete answers for any prohibited substance in their sample, however it got there.\u003c\/p\u003e\u003cp\u003eOral excretion studies give detection times. At the Institute of Legal Medicine in Strasbourg, a single volunteer took one oral amount in the milligram range; unchanged S-23 was found in hydrolysed urine from 2 hours to 28 days afterwards, as was a hydroxylated metabolite (Ameline et al., 2022). At the German Sport University Cologne, volunteers took single and repeated amounts of 1, 10 or 50 micrograms, the scale of a contaminated product. With a method able to detect 1 picogram per millilitre, a single microgram was traced for an average of up to 253 hours, about ten days, and a single 50 micrograms for up to 544 hours, about 23 days; 18 metabolites were identified (Alhalabi et al., 2025).\u003c\/p\u003e\u003cp\u003eThose figures come from one person and from small groups given very small amounts. Detection after repeated or larger milligram quantities has not been studied, so for this product: detectable, window not established. Anyone subject to anti-doping rules should treat any contact with S-23 as a risk of an adverse finding.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eWe know of no published stability study of S-23 in any form, so iMuscle's printed expiry or best-before date is the working limit, and a certificate describes the batch on its test date, not on the day the pot is opened.\u003c\/p\u003e\u003cp\u003eKeep the capsules in their original pot with the lid closed, because its lot number links them to any certificate. Store it cool, dry and dark, in a cupboard rather than a kitchen, bathroom or windowsill; humidity softens shells and makes powder cake. Let a cold pot reach room temperature before opening it so condensation does not form inside. Shells that have darkened, gone soft or fused together suggest the contents have changed since the batch was tested; keep that pot apart and \u003ca href=\"\/en-ro\/pages\/contact\"\u003etell us\u003c\/a\u003e its lot number.\u003c\/p\u003e\u003cp\u003eWear gloves whenever a capsule is opened or powder is spilled, and work away from food and drink. Label anything taken out of the pot with compound, lot and date. Store the pot where children and pets cannot reach it, and treat unwanted material as chemical waste under local rules rather than tipping it into a household bin or drain. Unopened items can be returned within 30 days, so a pot left sealed keeps that option open.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAryl-propionamide\u003c\/strong\u003e: the structural series of S-23, ostarine (S-22) and andarine (S-4), source of the S-numbered codes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull agonist\u003c\/strong\u003e: a compound that activates a receptor as completely as the body's own hormone, as S-23 did in 2009 cell assays; some related SARMs are only partial agonists.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInhibitory constant (Ki)\u003c\/strong\u003e: how tightly a compound binds a receptor in a competition assay; lower means tighter, about 1.7 nanomolar for S-23.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLevator ani\u003c\/strong\u003e: a small androgen-sensitive pelvic muscle weighed in rat studies as a marker of anabolic activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLH and FSH\u003c\/strong\u003e: luteinising hormone and follicle-stimulating hormone, released by the pituitary gland to drive testosterone and sperm production in the testes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpermatogenesis\u003c\/strong\u003e: sperm production in the testes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReference standard\u003c\/strong\u003e: material of certified identity used as the benchmark for identifying and measuring a sample.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHydrolysed urine\u003c\/strong\u003e: urine treated with an enzyme that strips attached groups such as glucuronic acid, freeing a compound and its metabolites for measurement.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdverse analytical finding\u003c\/strong\u003e: a laboratory's formal report that a prohibited substance or its metabolite is present in an athlete's sample.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: the anti-doping rule that athletes answer for whatever is found in their sample, whatever its source.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eAbout iMuscle S-23\u003c\/h2\u003e\u003cp\u003eiMuscle's S-23 pot has a magenta label with S-23 in large type under the iMUSCLE logo, and its front box reads 60 capsules, 15 mg each. The gallery shows the front of the pot and two test documents but no side panel, so the front label is the packaging evidence here. The brand's Romanian site gives the product as S-23, \"60\/15mg\", matching our record of 15 mg per capsule and 900 mg per pot.\u003c\/p\u003e\u003cp\u003eS-23 sits in iMuscle's standard line of single pots but in none of the eight iMuscle stacks we list, so this pot is the only form in which we sell it. The brand operates web shops in a number of European countries, among them imuscle.ro in Romanian, and its About page lists ten countries it supplies, the UK included. That page names no UK retailer, and Free Muscle does not claim to be an authorised one. Other iMuscle products are on the \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle brand page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eS-23 is a non-steroidal SARM characterised in rats in a 2009 study of hormonal male contraception; no clinical trial in people has been published. It is not licensed in the UK and WADA bans it under S1. iMuscle is currently the only maker of S-23 we stock, and the \u003ca href=\"\/en-ro\/collections\/s-23\"\u003eS-23 collection\u003c\/a\u003e is where other brands would appear.\u003c\/p\u003e\u003cp\u003eThe documents are a test protocol numbered RN18674, from a laboratory in Sofia and naming iMuscle LTD. as manufacturer, and an HPLC print-out for S23 with lot 20210908; both date to 2021, and no lot number appears on the protocol. Treat them as a record of an earlier test, not of the pot you would receive. \u003ca href=\"\/en-ro\/pages\/contact\"\u003eSend us\u003c\/a\u003e your pot's lot code to find out what iMuscle has supplied for it; Janoshik testing does not extend to this brand.\u003c\/p\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/s-23\"\u003eAll brands of S-23\u003c\/a\u003e, compared on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003eRelated SARMs: \u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 (Testolone)\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/andarine\"\u003eAndarine (S-4)\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/ostarine\"\u003eOstarine (MK-2866)\u003c\/a\u003e and \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eall SARMs\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eJones A, et al. Preclinical characterization of a (S)-N-(4-cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro, 4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide: a selective androgen receptor modulator for hormonal male contraception. Endocrinology. 2009;150(1):385-95. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18772237\/\" rel=\"noopener\"\u003ePMID: 18772237\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eAmeline A, et al. In vitro characterization of S-23 metabolites produced by human liver microsomes, and subsequent application to urine after a controlled oral administration. J Pharm Biomed Anal. 2022;212:114660. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35182830\/\" rel=\"noopener\"\u003ePMID: 35182830\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eAlhalabi H, et al. Investigations Into the Urinary Metabolite Elimination Profile of the Selective Androgen Receptor Modulator S-23 in Studies Mimicking Contaminated Product Ingestion for Doping Control Purposes. Biomed Chromatogr. 2025;39(6):e70090. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40277337\/\" rel=\"noopener\"\u003ePMID: 40277337\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34565686\/\" rel=\"noopener\"\u003ePMID: 34565686\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468980138210,"sku":null,"price":42.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/S-23_800x_0f998b39-6402-4c4a-9f31-a7dfe2de1826.jpg?v=1789931414"},{"product_id":"imuscle-stenabolic-sr-9009-60-10mg","title":"iMuscle Stenabolic SR-9009 — 60 caps, 10mg","description":"\u003cp\u003e\u003cstrong\u003eiMuscle Stenabolic SR-9009, 60 caps, 10mg\u003c\/strong\u003e is an iMuscle listing of SR9009, labelled at 10 mg per capsule, 60 capsules per pack. It is supplied through the \u003ca href=\"\/en-ro\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e range for laboratory research only, is not for human consumption, and is sold to adults aged 18 and over. Below: what the published research on SR9009 reports, what the label documents, where the compound stands in UK law and in sport, how to read a batch certificate for it, and how batch certificates are handled for iMuscle products.\u003c\/p\u003e\n\u003ch2\u003eAbout SR9009\u003c\/h2\u003e\n\u003cp\u003eSR9009, sold under the name Stenabolic, is a synthetic agonist of REV-ERB alpha and REV-ERB beta, nuclear receptors that connect the circadian clock to the expression of metabolic genes. It was developed at the Scripps Research Institute by Burris and colleagues. It is not a SARM and has no described activity at the androgen receptor.\u003c\/p\u003e\n\u003cp\u003ePubChem records it as CID 57394020, CAS number 1379686-30-2, molecular formula C20H24ClN3O4S and molecular weight 437.9, with InChIKey MMJJNHOIVCGAAP-UHFFFAOYSA-N. Its systematic name is ethyl 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate. These identifiers are what any certificate of analysis should be checked against.\u003c\/p\u003e\n\u003ch2\u003eWhat the published research reports\u003c\/h2\u003e\n\u003cp\u003eIn a 2012 study published in Nature, mice given SR9009 by injection showed altered circadian behaviour, and the circadian pattern of metabolic gene expression in liver, muscle and fat changed, with increased energy expenditure. Diet-induced obese mice treated with the agonist lost fat mass and showed improved dyslipidaemia and hyperglycaemia (Solt et al., 2012). A 2013 mouse study led from the Institut Pasteur de Lille, with the Scripps group as co-authors, linked REV-ERB alpha to mitochondrial number in skeletal muscle and reported that pharmacological activation of the receptor increased exercise capacity in mice (Woldt et al., 2013). In 2019 a group at the University of Pennsylvania reported that SR9009 changed cell proliferation and metabolism in cells lacking REV-ERB altogether, showing that some of its effects are off-target (Dierickx et al., 2019).\u003c\/p\u003e\n\u003cp\u003eThe animal studies used injection, and there are no published human trials or human pharmacokinetic data, so the behaviour of an oral capsule is unknown. It has never been approved as a medicine. Two further papers matter for anyone assessing SR9009 bought online. A Ghent University doping control laboratory confirmed SR9009 in a black market product bought over the internet and described eight metabolites formed by human liver enzymes in the test tube (Geldof et al., 2016). A 2017 analysis of 44 products sold online as SARMs found that 17 contained another unapproved drug, SR9009 among them, and that in only 18 of the 44 (41%) did the amount of active compound match the label (Van Wagoner et al., 2017). Nothing above is a claim about this product.\u003c\/p\u003e\n\u003ch2\u003eThis listing\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eManufacturer: iMuscle\u003c\/li\u003e\n\u003cli\u003eCompound: SR9009 (Stenabolic)\u003c\/li\u003e\n\u003cli\u003eForm: Capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStrength: 10 mg per capsule, as stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eTotal in pack: 600 mg (10 mg x 60 capsules)\u003c\/li\u003e\n\u003cli\u003eBatch certificate of analysis: shown where iMuscle supplies one for the batch we hold\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe 600 mg total is a label figure, calculated from the manufacturer's stated strength and capsule count. It becomes a measured figure only when a batch certificate reports content per capsule. Our guide to \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e shows how to compare it with other SR9009 listings.\u003c\/p\u003e\n\u003ch2\u003eSR9009 in the UK: buying, legal status and what to check\u003c\/h2\u003e\n\u003cp\u003eThe searches \"SR9009 UK\", \"stenabolic UK\" and \"SR9009 UK sarms\" hide two questions: may it lawfully be sold here, and how do you tell a sound listing from a poor one. SR9009 is not a licensed medicine in the UK, has not been assessed by the MHRA, and is not an authorised food supplement. It is not a controlled drug. It is sold for laboratory research to adults aged 18 and over and is not for human consumption. Any seller offering instructions for taking it is marketing it outside that research basis.\u003c\/p\u003e\n\u003cp\u003eIn sport the position is stricter. SR9009 is named on the WADA Prohibited List under section S4 (hormone and metabolic modulators) alongside GW1516 and is prohibited at all times. Anyone subject to anti-doping rules should consult the current list. Our \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eresearch guide\u003c\/a\u003e covers the wider legal picture for compounds sold next to SARMs.\u003c\/p\u003e\n\u003cp\u003eThe 2017 finding that SR9009 turned up in products labelled as something else is the best reason to judge an SR9009 listing on documents rather than on ratings or forum posts. The points worth checking, and how this listing answers each:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eNamed manufacturer and compound identifiers.\u003c\/strong\u003e This listing: iMuscle, with CAS 1379686-30-2 and the molecular formula given above, so a certificate can be matched to SR9009 and not to its sister compound SR9011.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrength and count on the label.\u003c\/strong\u003e iMuscle states 10 mg in each of 60 capsules.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate tied to the stock on sale.\u003c\/strong\u003e This listing: shown only where iMuscle supplies one for the batch we hold, and we say plainly when there is none.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWho is selling, and to whom.\u003c\/strong\u003e Here the seller is FreeMuscle, registered in Andorra, with UK operations and dispatch in Scunthorpe; buyers must be 18 or over, and unopened items may be returned within 30 days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow it travels.\u003c\/strong\u003e Every UK order goes out free with tracking, in plain packaging. Anything ordered by 2pm on a weekday is processed that day, and parcels to the EU take 3-7 working days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo usage guidance.\u003c\/strong\u003e This listing gives none, and neither does anything else on this site.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eDelivery and returns terms are set out on our \u003ca href=\"\/en-ro\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages. The \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e applies the same tests to any shop, including this one.\u003c\/p\u003e\n\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\n\u003cp\u003eSR9009 is offered in three formats across the market: filled capsules like these, liquids in which the compound is dissolved or suspended, and loose powder. None of them has been studied for SR9009 in people. The published mouse studies used injected solutions prepared in the laboratory, so no commercial format, capsule or liquid, reproduces the conditions of that research. What differs is how each fixes the amount per unit.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsule fill.\u003c\/strong\u003e The stated 10 mg is blended with an inert filler and dosed into each shell by weight. Variation comes from blend uniformity and fill weight, and a laboratory can open and assay individual capsules to check both.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquid.\u003c\/strong\u003e The label states a concentration, often in a carrier that is not identified. The figure holds only while the compound stays evenly dissolved or suspended, and any volume drawn off depends on how accurately it is measured.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePowder.\u003c\/strong\u003e Accuracy moves entirely to the researcher's balance and technique, and a certificate describes the bulk material only.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe search \"SR9009 peptide\" reflects a common confusion. SR9009 is not a peptide: it has no amino acid chain for digestive enzymes to cut, which is the main obstacle for peptides given by mouth (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides work?\u003c\/a\u003e). That does not mean oral SR9009 is well absorbed. With no human pharmacokinetic study published, the fraction of an oral amount reaching the circulation in people is simply unknown, and we do not suggest otherwise. For this pack, the useful property of the capsule format is that it gives a countable unit that a laboratory can test.\u003c\/p\u003e\n\u003ch2\u003eSR9009 compared with Cardarine\u003c\/h2\u003e\n\u003cp\u003e\"Stenabolic vs cardarine\" is a frequent search, because the two are sold next to each other and both appear in section S4 of the WADA list. The overlap largely ends there. The table sets out where they differ.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eQuestion\u003c\/th\u003e\n\u003cth\u003eSR9009 (Stenabolic)\u003c\/th\u003e\n\u003cth\u003eCardarine (GW-501516)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eReceptor it was designed for\u003c\/td\u003e\n\u003ctd\u003eREV-ERB alpha and beta, circadian clock receptors\u003c\/td\u003e\n\u003ctd\u003ePPAR-delta, a fatty acid metabolism receptor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWho made it and why\u003c\/td\u003e\n\u003ctd\u003eAn academic research tool for probing the clock\u003c\/td\u003e\n\u003ctd\u003eA pharmaceutical candidate for blood lipid disorders\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHighest level of evidence\u003c\/td\u003e\n\u003ctd\u003eMouse and cell studies only\u003c\/td\u003e\n\u003ctd\u003eShort human lipid trials\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKnown specificity problem\u003c\/td\u003e\n\u003ctd\u003eEffects in cells with no REV-ERB (2019)\u003c\/td\u003e\n\u003ctd\u003eDevelopment halted over rodent tumour findings\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOral data in people\u003c\/td\u003e\n\u003ctd\u003eNone published\u003c\/td\u003e\n\u003ctd\u003eGiven by mouth in human trials\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK position\u003c\/td\u003e\n\u003ctd\u003eUnlicensed, research use only, 18+\u003c\/td\u003e\n\u003ctd\u003eUnlicensed, research use only, 18+\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSport\u003c\/td\u003e\n\u003ctd\u003eWADA S4, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eWADA S4, prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003ePut in plain terms, Cardarine is a failed drug candidate with some human data and a serious toxicology history, while SR9009 is a laboratory probe that was never taken into people at all. Neither is a SARM. The 2019 off-target finding also means that effects attributed to REV-ERB in SR9009 studies may partly come from other targets. We make no claim about either compound used together with any other. The \u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eCardarine collection\u003c\/a\u003e lists the brands we hold, and our article on \u003ca href=\"\/en-ro\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003ewhy Cardarine development stopped\u003c\/a\u003e gives its history. People also search \"SR9009 vs SR9011\": SR9011 is the sister compound described in the same 2012 paper, with a similar target and no human data either. We do not stock it.\u003c\/p\u003e\n\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\n\u003cp\u003eCertificates work differently for our own label and for iMuscle. Every Free Muscle-brand batch goes to Janoshik Analytical, an independent laboratory, and the certificate is emailed on request. iMuscle is an outside manufacturer stocked through Muscle Market, so for this product a certificate of analysis appears only when iMuscle provides one for the particular batch on our shelves. We do not pass off a generic PDF without a batch number as a batch certificate. Send us the product name by email and we will forward whatever we hold for the current batch, or tell you directly that nothing is held.\u003c\/p\u003e\n\u003cp\u003eIf an iMuscle certificate is available for this batch, read it in this order:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity\u003c\/strong\u003e: the compound named should be SR9009, not SR9011 or a generic \"Stenabolic\" with no structure. HPLC identifies it by comparing retention time with a reference standard; LC-MS adds a mass, which should fit the 437.9 molecular weight given above.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity\u003c\/strong\u003e: a percentage from HPLC peak areas. It tells you how much of the detected material is SR9009, not how many milligrams a capsule holds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule\u003c\/strong\u003e: the measured amount in one capsule, which is the figure to set against the stated 10 mg.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number\u003c\/strong\u003e: must match the code on the pack you received.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory and test date\u003c\/strong\u003e: name the analyst and show whether the result is recent enough to cover this stock.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor this brand, gaps mean specific things. No certificate means this listing makes no documented claim about identity, purity or content beyond the manufacturer's label. Purity with no content figure confirms the molecule but leaves the 10 mg unverified. A batch number that does not match your pack means the certificate describes different stock, and you should \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e. Our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests page\u003c\/a\u003e and the article on \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e cover the methods in more depth.\u003c\/p\u003e\n\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\n\u003cp\u003eFor athletes, the regulatory point is simple: SR9009 is in section S4 of the WADA Prohibited List and is banned in and out of competition, and under strict liability a positive sample counts regardless of how the substance got there, including through a mislabelled product. The 2016 Ghent study identified eight human liver metabolites of SR9009 so that screens could look for breakdown products as well as the parent compound, and it recommended adding SR9009 to routine screening. When the authors searched 1,511 stored doping control urine results, they found neither SR9009 nor its metabolites in those routine samples.\u003c\/p\u003e\n\u003cp\u003eNo verified study has measured how long SR9009 or its metabolites remain detectable in human urine after exposure. The honest answer for this capsule product is therefore: detectable, window not established. Anyone subject to anti-doping rules should treat it as prohibited.\u003c\/p\u003e\n\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\n\u003cp\u003eNo stability study of SR9009 in capsule form has been published, so the manufacturer's expiry date, where iMuscle prints one, is the only product-specific guide. General laboratory practice for small organic compounds applies: protect from heat, moisture and light.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLeave the capsules in the tub they arrived in: the batch code printed on it is the only link to a certificate.\u003c\/li\u003e\n\u003cli\u003eStore somewhere cool, dry and dark, away from radiators, windowsills and steamy rooms; capsule shells soften in humid air and turn brittle in very dry air.\u003c\/li\u003e\n\u003cli\u003eLog the batch number, date received and date opened.\u003c\/li\u003e\n\u003cli\u003eWear nitrile gloves when handling opened capsules or spilled powder, and clean surfaces afterwards.\u003c\/li\u003e\n\u003cli\u003eSurplus or out-of-date capsules belong in a chemical waste stream, never in household bins or down a drain.\u003c\/li\u003e\n\u003cli\u003eStore on a shelf that children and pets cannot reach, and never in a fridge or cupboard used for food.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eGlossary\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eREV-ERB alpha and beta\u003c\/strong\u003e: nuclear receptors that repress clock and metabolic genes on a daily cycle; SR9009 was designed to activate them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCircadian clock\u003c\/strong\u003e: the internal roughly 24-hour cycle of gene activity found in most cells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAgonist\u003c\/strong\u003e: a molecule that binds a receptor and switches it on.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOff-target effect\u003c\/strong\u003e: an action of a compound that does not go through its intended receptor, as shown for SR9009 in 2019.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSR9011\u003c\/strong\u003e: a closely related REV-ERB agonist described alongside SR9009 in 2012; not stocked here.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePharmacokinetics\u003c\/strong\u003e: the study of what the body does to a substance over time, from uptake to elimination; no human data exist for SR9009.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver microsomes\u003c\/strong\u003e: fractions of liver cells holding drug-metabolising enzymes, used in the test tube to predict metabolites.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolite\u003c\/strong\u003e: a product the body forms by altering a substance, often the target of anti-doping tests.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReference standard\u003c\/strong\u003e: a highly characterised sample of a compound that a laboratory uses to confirm identity and quantity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetention time\u003c\/strong\u003e: the point at which a compound emerges from an HPLC column; a sample and a standard of the same substance should emerge together.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: under anti-doping rules, a finding in a sample stands against the athlete whether or not they knew the substance was there.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAbout iMuscle Stenabolic SR-9009\u003c\/h2\u003e\u003cp\u003eSTENABOLIC is the name on iMuscle's SR9009 pot, printed on a teal label with SR and 9009 underneath; Stenabolic is a trade name for the compound, not a different substance. The front box reads 60 capsules, 10 mg each, and on imuscle.ro the listing reads Stenabolic SR-9009, \"60\/10mg\". No side panel photograph is included, so the front of the pot is the label evidence in this gallery.\u003c\/p\u003e\u003cp\u003eLike S-23, this pot is outside all eight iMuscle stacks we list. SR9009 is not a SARM, although iMuscle sells it within its SARMs range. The brand's About page splits its products into the nine single pots of its standard line, all stocked here, and a combined series that we do not carry. Browse the rest on the \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle brand page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eSR9009 activates the REV-ERB receptors that link the body clock to metabolic genes. It came out of academic work at Scripps Research, has been studied in mice and cells but in no published human trial, holds no UK licence, and appears in section S4 of the WADA list. No other SR9009 brand is on our shelves as of October 2026; the \u003ca href=\"\/en-ro\/collections\/sr9009\"\u003eSR9009 collection\u003c\/a\u003e and the \u003ca href=\"\/en-ro\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 research guide\u003c\/a\u003e carry the detail.\u003c\/p\u003e\u003cp\u003eTwo 2021 documents are shown: protocol RN18694 from a Sofia laboratory, which gives iMuscle LTD. as maker and records a single-sample HPLC assay with no lot number, and an English print-out for SR9009 with lot 20210911. iMuscle also states that it tests all its lots at an independent European laboratory. Neither document is matched to current stock, so quote the lot code on your pot when you \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e; the Janoshik programme is for Free Muscle's own brand, not iMuscle.\u003c\/p\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/collections\/sr9009\"\u003eAll brands of SR9009 we stock, compared\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 (Stenabolic): REV-ERB agonist research and the bioavailability problem\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eCardarine\u003c\/a\u003e and the wider \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eSARMs range\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003eBatch testing and certificates of analysis\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice. Summaries of published research describe study findings and are not claims about any product.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eSolt LA, et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature. 2012;485(7396):62-8. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22460951\/\" rel=\"noopener\"\u003ePMID: 22460951\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eWoldt E, et al. Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy. Nat Med. 2013;19(8):1039-46. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23852339\/\" rel=\"noopener\"\u003ePMID: 23852339\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eDierickx P, et al. SR9009 has REV-ERB-independent effects on cell proliferation and metabolism. Proc Natl Acad Sci U S A. 2019;116(25):12147-12152. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31127047\/\" rel=\"noopener\"\u003ePMID: 31127047\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eGeldof L, et al. In Vitro Metabolic Studies of REV-ERB Agonists SR9009 and SR9011. Int J Mol Sci. 2016;17(10):1676. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27706103\/\" rel=\"noopener\"\u003ePMID: 27706103\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eVan Wagoner RM, et al. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004-2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29183075\/\" rel=\"noopener\"\u003ePMID: 29183075\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468980170978,"sku":null,"price":48.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/STENABOLIC_3333x_3eb916f3-0538-401c-8e12-157d57e3440a.jpg?v=1789931416"},{"product_id":"imuscle-testolon-rad-140-60-10mg","title":"iMuscle Testolone RAD-140 — 60 caps, 10mg","description":"\u003cp\u003eiMuscle Testolone RAD-140 comes as 60 capsules stated at 10 mg each, giving 600 mg of RAD-140 per pack. RAD-140, or testolone, is a non-steroidal selective androgen receptor modulator with a single published clinical trial. iMuscle manufactures the product; Free Muscle stocks it in the Muscle Market range and ships it from the UK to adults for laboratory research only.\u003c\/p\u003e\u003ch2\u003eAbout RAD-140\u003c\/h2\u003e\u003cp\u003eRAD-140 is a synthetic, non-steroidal selective androgen receptor modulator, commonly called testolone. Like other SARMs it binds the androgen receptor, but it has no steroid ring system and its structure is unrelated to testosterone. Radius Health described its discovery in 2011 as a potent, orally bioavailable SARM and reported its characterisation in several preclinical animal models of anabolic androgen action (Miller et al., 2011).\u003c\/p\u003e\u003cp\u003eRAD-140 later entered a Phase 1 oncology trial in women with ER-positive, HER2-negative advanced breast cancer, published in 2022 (LoRusso et al., 2022). Twenty-two heavily pretreated patients took part. The adverse events recorded most often were raised AST (59%), ALT (45%) and bilirubin (27%), and grade 3 or 4 events occurred in 16 of the 22. Outside clinical research, published case reports link RAD-140 to cholestatic liver injury, including a biopsy-supported case in a 24-year-old man that resolved after exposure stopped (Leung et al., 2022).\u003c\/p\u003e\u003cp\u003eThe only other structured human data come from anti-doping research: a 2022 Cologne study gave adult male volunteers microgram amounts to chart how RAD-140 is excreted, covered under detection below (Wagener et al., 2022). No published trial has measured muscle, strength or body composition in healthy adults. The research described here relates to the molecule in laboratory and clinical settings and is not a claim about this listing.\u003c\/p\u003e\u003ch3\u003eChemical identity\u003c\/h3\u003e\u003cp\u003eIdentifiers from PubChem, against which a laboratory result can be checked:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystematic name\u003c\/strong\u003e: 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number\u003c\/strong\u003e: 1182367-47-0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormula and molecular weight\u003c\/strong\u003e: C20H16ClN5O2, 393.8 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInChIKey\u003c\/strong\u003e: XMBUPPIEVAFYHO-KPZWWZAWSA-N\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePubChem CID\u003c\/strong\u003e: 44200882\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOther names\u003c\/strong\u003e: testolone, vosilasarm, EP0062\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCompound: RAD-140 (Testolone)\u003c\/li\u003e\n\u003cli\u003eBrand: iMuscle\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStated strength: 10 mg per capsule (manufacturer's label claim)\u003c\/li\u003e\n\u003cli\u003eStated total per pack: 600 mg\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThe strength is the manufacturer's label claim; only a batch certificate confirms it. To compare brands of RAD-140, use total milligrams per pack, as explained in \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e. Of the RAD-140 listings we stock, only this one and the Free Muscle-brand pack state a per-capsule strength; the Yakka Strength and Thoroughbred Labs listings do not.\u003c\/p\u003e\u003ch2\u003eRAD-140 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eUK searches such as \"RAD140 for sale UK\" and \"testolone RAD 140 UK\" raise two practical questions: what the law allows, and what evidence a listing should offer.\u003c\/p\u003e\u003ch3\u003eLegal status\u003c\/h3\u003e\u003cp\u003eNo UK medicines licence exists for RAD-140: the MHRA has never granted it a marketing authorisation, and no regulator elsewhere has licensed it either. Nor is it an authorised food supplement, so selling it for human consumption would be unlawful. It is not a controlled drug. Free Muscle supplies it only as a research compound, to adults aged 18 or over, for laboratory use. WADA prohibits it at all times under section S1 (anabolic agents) of its Prohibited List. Buyers are responsible for the rules that apply to them, including any anti-doping code. Background on the class is in \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eWhy a label proves little on its own\u003c\/h3\u003e\u003cp\u003eThe case for checking is empirical. A US anti-doping laboratory, working with the US Anti-Doping Agency, bought 44 products sold online as SARMs and analysed them: in 26 the amount of active compound differed substantially from the label, and 17 contained a different unapproved drug altogether, among them ibutamoren, GW501516 and SR9009 (Van Wagoner et al., 2017). It concerned US websites in 2016, not this product.\u003c\/p\u003e\u003ch3\u003eQuestions to ask of any listing, answered for this one\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eQuestion\u003c\/th\u003e\n\u003cth\u003eThis iMuscle listing\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eIs a strength printed, with a capsule count?\u003c\/td\u003e\n\u003ctd\u003eYes: 10 mg per capsule, 60 capsules, 600 mg per pack (manufacturer's claim)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWho makes it?\u003c\/td\u003e\n\u003ctd\u003eiMuscle\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWho sells it, and from where?\u003c\/td\u003e\n\u003ctd\u003eFreeMuscle, a business registered in Andorra, dispatching from Scunthorpe\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIs there a certificate for the batch sold?\u003c\/td\u003e\n\u003ctd\u003eShown only where iMuscle supplies one for the batch we hold\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAre the terms research-only?\u003c\/td\u003e\n\u003ctd\u003eYes: laboratory research, adults 18+, no directions for use and no promised outcomes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHow does it travel?\u003c\/td\u003e\n\u003ctd\u003eFree tracked delivery on every UK order, in plain packaging; same-day processing for orders before 2pm Monday to Friday; 3-7 working days to the EU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCan it be returned?\u003c\/td\u003e\n\u003ctd\u003eUnopened items, within 30 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eOnly the certificate depends on the manufacturer. Personal accounts under \"RAD 140 UK reddit\" or \"best RAD 140 UK\" describe experiences, not the contents of a pack; only a batch certificate measures those. More checks are in \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eiMuscle is a third-party brand, so any certificate of analysis (COA) for this product is the manufacturer's, not ours. A COA is shown only where iMuscle supplies one for the batch we hold; a generic document is not a substitute for a batch certificate. Free Muscle-brand compounds are assayed batch by batch at Janoshik Analytical; that programme does not cover iMuscle. A genuine batch certificate names its method, HPLC or LC-MS; check an iMuscle certificate in this order:\u003c\/p\u003e\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound named.\u003c\/strong\u003e It should say RAD-140, or a synonym such as testolone or vosilasarm. A certificate for RAD-150, or for an unnamed \"SARM\", is not a certificate for this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity result.\u003c\/strong\u003e A chromatogram alone shows that something eluted where a RAD-140 reference standard does; a mass spectrum shows a molecule of the right mass, for protonated RAD-140 an ion at m\/z 394.1065 (Wagener et al., 2022).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e A share of chromatogram peak area. It describes how clean the material is; a capsule could meet a high purity figure and still hold far more or far less than 10 mg.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e The measured figure to set against the 10 mg claim; sixty times it is the real pack total. One assay gives the average of the capsules tested, not the spread between them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLot number, test date and laboratory.\u003c\/strong\u003e The lot must match your pack; the date shows how old the result is.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003ePurity without a content figure leaves the 10 mg claim, and with it the 600 mg total, unconfirmed. A result with no stated method cannot be weighed. A lot number that is missing, or differs from the one on your pot, means the certificate concerns another production run. In any of those cases, \u003ca href=\"\/en-ro\/pages\/contact\"\u003eask us\u003c\/a\u003e before relying on the batch. See also \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e and our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eTestolone tablets and RAD-140 \"research liquids\" are also on the market, and searches such as \"RAD 140 tablets\" and \"RAD 140 liquid UK\" reflect that. Whatever the format, the molecule is RAD-140; what varies is how reliably the printed amount reaches each unit, and no one has published a comparison for this compound.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eWhat the label figure relies on\u003c\/th\u003e\n\u003cth\u003eWhat its certificate should state\u003c\/th\u003e\n\u003cth\u003eStorage sensitivity\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCapsule (this product)\u003c\/td\u003e\n\u003ctd\u003eUniform mixing of the powder and a consistent fill in every shell\u003c\/td\u003e\n\u003ctd\u003eMilligrams per capsule, to set against 10 mg\u003c\/td\u003e\n\u003ctd\u003eMoisture: shells soften and the powder clumps\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTablet\u003c\/td\u003e\n\u003ctd\u003eUniform mixing, then pressing with binders and sometimes a coating\u003c\/td\u003e\n\u003ctd\u003eMilligrams per tablet\u003c\/td\u003e\n\u003ctd\u003eMoisture and breakage\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLiquid\u003c\/td\u003e\n\u003ctd\u003eComplete dissolution, a solution that stays stable, and accurate measuring of every volume drawn\u003c\/td\u003e\n\u003ctd\u003eMilligrams per millilitre, on the test date\u003c\/td\u003e\n\u003ctd\u003eChemical change in solution; evaporation concentrates what remains\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eBecause RAD-140 is a small molecule rather than a peptide, the question that dominates debate over swallowed peptides, whether digestive enzymes break them down, does not arise in the same way (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e). Both human studies gave it by mouth; we know of no published study of RAD-140 by injection.\u003c\/p\u003e\u003ch2\u003eRAD-140 compared with RAD-150 (TLB-150)\u003c\/h2\u003e\u003cp\u003e\"RAD 140 vs RAD 150\", also searched as \"TLB 150 vs RAD 140\", is the comparison most often made for this compound.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eRAD-140 (this product)\u003c\/th\u003e\n\u003cth\u003eRAD-150 (TLB-150)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eRelationship\u003c\/td\u003e\n\u003ctd\u003eParent molecule\u003c\/td\u003e\n\u003ctd\u003eBenzoate ester of RAD-140, recorded in PubChem as \"TLB 150 Benzoate\" (CID 68547459)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and molecular weight\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2, 393.8\u003c\/td\u003e\n\u003ctd\u003eC27H20ClN5O3, 497.9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWhere it appears in print\u003c\/td\u003e\n\u003ctd\u003ePeer-reviewed journals since 2011\u003c\/td\u003e\n\u003ctd\u003eA patent, US 8,629,167 (compound 87); no journal papers\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIC50 for androgen receptor binding, patent assay\u003c\/td\u003e\n\u003ctd\u003e2 nM\u003c\/td\u003e\n\u003ctd\u003e130 nM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStudies in people\u003c\/td\u003e\n\u003ctd\u003eOne cancer trial and one anti-doping excretion study\u003c\/td\u003e\n\u003ctd\u003eNo published study\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA Prohibited List\u003c\/td\u003e\n\u003ctd\u003eListed by name in S1.2\u003c\/td\u003e\n\u003ctd\u003eAbsent from the examples; covered by the section's open wording\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThe binding figures come from the patent, as deposited in PubChem, not from a journal, and describe the intact molecules in a commercial binding kit. On them the ester bound the receptor about 65 times more weakly than RAD-140. A living system may split an ester back to its parent, so this does not settle what RAD-150 does there, but it argues against the ester being a stronger ligand in its own right. Claims that it lasts longer or acts more strongly are unmeasured, and whether, and how fast, it becomes RAD-140 in the body is unknown.\u003c\/p\u003e\u003cp\u003eThe heavier formula matters for labels too: roughly a fifth of the ester's mass comes from the added benzoate portion, so a milligram figure for RAD-150 and the 600 mg on this pack do not describe the same quantity of the RAD-140 structure. Legally the two are alike: neither is a licensed medicine or an authorised food, and both are sold here for laboratory research only. WADA names RAD140 in S1.2; RAD-150 is absent, but the section introduces its examples with \"including, but not limited to\", so absence is no exemption. Brands held are in the \u003ca href=\"\/en-ro\/collections\/rad-150\"\u003eRAD-150 (TLB-150) collection\u003c\/a\u003e; the chemistry is set out in \u003ca href=\"\/en-ro\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150 (TLB-150)\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eRAD-140 is named, as RAD140, under S1.2 (other anabolic agents) of the WADA Prohibited List, banned at all times. Under strict liability an adverse analytical finding stands against the athlete whatever its source, be it a research compound, a mislabelled product or a contaminated supplement.\u003c\/p\u003e\u003cp\u003eIts persistence in urine has been measured, though only after very small amounts. At the German Sport University Cologne, six excretion studies, each with five adult male volunteers, used single or five daily amounts of 1, 10 or 50 micrograms, and their urine was analysed by LC-HRMS\/MS (Wagener et al., 2022). Unchanged RAD-140 outlasted all six metabolites tracked in every group. After one 50 microgram amount it was found up to 696 hours later, about 29 days; after five daily amounts of 50 micrograms, up to 912 hours, about 38 days, after the last. Part of the aim was to help laboratories judge whether a finding reflects deliberate use or contamination.\u003c\/p\u003e\u003cp\u003eEvery figure above comes from microgram exposures. How long RAD-140 remains detectable after milligram quantities, such as the 10 mg stated per capsule here, has not been reported that we know of, so for this product: detectable, window not established. The Cologne results set no upper limit, and anyone subject to testing should regard any contact with RAD-140 as a positive-test risk.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eShelf life for RAD-140 capsules has not been established in any published study we know of. Work to iMuscle's printed expiry or best-before date, where there is one, and to the age of any certificate.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the original pot.\u003c\/strong\u003e A certificate refers to the lot number printed on it, so capsules moved to another container can no longer be matched to one. Close the lid straight after each opening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCool, dry and dark.\u003c\/strong\u003e A cupboard away from radiators, kettles and bathrooms. Humidity is the chief threat: shells absorb water and turn soft and sticky, and moisture that reaches the powder can hasten chemical breakdown.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo temperature swings.\u003c\/strong\u003e A cold pot brought into a warm room gathers condensation; let it reach room temperature before opening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRecords.\u003c\/strong\u003e Note when the seal was first broken, and label anything removed from the pot with compound, lot and date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHandling.\u003c\/strong\u003e Gloves for opened capsules or spilled powder, no eating or drinking nearby, storage beyond the reach of children and animals, and disposal through chemical waste routes rather than household bins or drains.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator, a label for non-steroidal molecules developed to switch on the androgen receptor in some tissues, chiefly muscle and bone, while sparing others.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReference standard\u003c\/strong\u003e: material of known identity and purity, run alongside a sample for comparison.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC\u003c\/strong\u003e: high-performance liquid chromatography; the sample is pushed through a packed column and each component shows as a peak on the chromatogram, whose areas give the purity figure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLC-MS\u003c\/strong\u003e: the same separation followed by a mass spectrometer, which identifies each component by its mass.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtonated molecule\u003c\/strong\u003e: a molecule carrying one extra hydrogen ion, the form in which LC-MS registers RAD-140, at m\/z 394.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAssay\u003c\/strong\u003e: the test of how much RAD-140 a capsule holds, as opposed to how clean it is.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEster\u003c\/strong\u003e: an acid joined to an alcohol group by a bond that water can break; RAD-150 is RAD-140 joined in this way to benzoic acid.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdverse analytical finding\u003c\/strong\u003e: the formal term for a laboratory report of a prohibited substance in an athlete's sample.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: the rule that athletes answer for any prohibited substance in their sample, however it got there.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMarketing authorisation\u003c\/strong\u003e: a regulator's permission, in the UK from the MHRA, to sell a product as a medicine; RAD-140 has none.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eAbout iMuscle Testolon (RAD-140)\u003c\/h2\u003e\u003cp\u003eiMuscle labels its RAD-140 as TESTOLON, in large letters on a blue label with RAD 140 below, so the pot may be searched for under either name. A box on the front gives 60 capsules at 10 mg each; the side panel names Testolone RAD140 at 10 mg per capsule alongside a chemical name and the brand's statement of purity tested above 97%. iMuscle's Romanian shop calls it Testolon RAD-140, \"60\/10mg\", in line with our 600 mg per pot.\u003c\/p\u003e\u003cp\u003eTestolon belongs to iMuscle's standard line of nine single pots and also features in three stacks we list: \u003ca href=\"\/en-ro\/products\/imuscle-cardarine-testolon-rad140\"\u003eCardarine and Testolon\u003c\/a\u003e, \u003ca href=\"\/en-ro\/products\/imuscle-ligandrol-testolon-yk-11\"\u003eLigandrol, Testolon and YK-11\u003c\/a\u003e and \u003ca href=\"\/en-ro\/products\/imuscle-testolon-yk11-ibutamoren\"\u003eTestolon, YK-11 and Ibutamoren\u003c\/a\u003e. The brand sells through its own websites in several EU countries and says its products reach ten countries including the UK; it lists no UK stockists, and we claim no official status. The whole range is on our \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eRadius Health designed RAD-140 as a non-steroidal SARM, and its only trial in people was a small phase 1 cancer study; it is unlicensed in the UK and sits in WADA section S1. On stated figures, the RAD-140 pots from \u003ca href=\"\/en-ro\/collections\/brand-yakka-strength\"\u003eYakka Strength\u003c\/a\u003e and \u003ca href=\"\/en-ro\/collections\/brand-thoroughbred-labs\"\u003eThoroughbred Labs\u003c\/a\u003e are also labelled 10 mg in 60 capsules, as is Free Muscle's own, the only one with each batch assayed at Janoshik. Compare them on the \u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 collection\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eThe gallery's protocol, RN18664, and its HPLC print-out for RAD140, lot 20210908, are both 2021 documents, and the protocol lists no lot number. They record a 2021 test of a sample attributed to iMuscle; they do not show what the pot in stock today contains. Read the lot code on the pot and \u003ca href=\"\/en-ro\/pages\/contact\"\u003eask us\u003c\/a\u003e for any iMuscle document covering it.\u003c\/p\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eAll brands of RAD-140 (Testolone)\u003c\/a\u003e, compared on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/products\/free-muscle-rad-140-testolone-10mg\"\u003eFree Muscle RAD-140 Testolone 10mg\u003c\/a\u003e, the own-brand pack, Janoshik-assayed batch by batch\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e, from animal studies to case reports\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eMiller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-9. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24900290\/\" rel=\"noopener\"\u003ePMID: 24900290\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34565686\/\" rel=\"noopener\"\u003ePMID: 34565686\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eVan Wagoner RM, et al. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004-2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29183075\/\" rel=\"noopener\"\u003ePMID: 29183075\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eWagener F, et al. Human In Vivo Metabolism and Elimination Behavior of Micro-Dosed Selective Androgen Receptor Modulator RAD140 for Doping Control Purposes. Metabolites. 2022;12(7):666. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35888790\/\" rel=\"noopener\"\u003ePMID: 35888790\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLeung K, et al. RAD-140 Drug-Induced Liver Injury. Ochsner J. 2022;22(4):361-365. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36561105\/\" rel=\"noopener\"\u003ePMID: 36561105\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468980203746,"sku":null,"price":39.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/TESTOLON.jpg?v=1789931418"},{"product_id":"imuscle-yk-11-60-10mg","title":"iMuscle YK-11 — 60 caps, 10mg","description":"\u003cp\u003eiMuscle YK-11 is supplied as 60 capsules stated at 10 mg each, giving 600 mg of YK-11 per pack. YK-11 is a steroidal partial agonist of the androgen receptor that is commonly sold alongside SARMs and is described in cell studies as a follistatin inducer. iMuscle manufactures it and Free Muscle stocks it in the Muscle Market range for laboratory research by adults only.\u003c\/p\u003e\n\u003ch2\u003eThis listing\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCompound: YK-11\u003c\/li\u003e\n\u003cli\u003eBrand: iMuscle\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStated strength: 10 mg per capsule (manufacturer's label claim)\u003c\/li\u003e\n\u003cli\u003eStated total per pack: 600 mg\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe strength is the manufacturer's label claim; only a batch certificate confirms it. To compare brands of YK-11, use total milligrams per pack: dividing the listed price by the 600 mg stated here gives the cost per stated milligram, as explained in \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eAbout YK-11\u003c\/h2\u003e\n\u003cp\u003eYK-11 is often grouped with SARMs, but it is a steroidal molecule: a 19-nor-pregnane derivative with a methyl ester side chain. It was described in 2011 by a group at Toho University in Japan, who showed in cell assays that it acts as a partial agonist at the androgen receptor, activating the receptor less fully than DHT (Kanno 2011).\u003c\/p\u003e\n\u003cp\u003eThe claim that YK-11 is a myostatin inhibitor comes from a 2013 study in C2C12 mouse myoblast cells, in which YK-11 increased expression of follistatin, a protein that binds myostatin, and promoted myogenic differentiation more than DHT did in that model (Kanno 2013). Both papers are cell-culture work. No human clinical trial of YK-11 has been published, so its pharmacokinetics, hormonal effects and liver tolerance in people are unknown.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIdentifier\u003c\/th\u003e\n\u003cth\u003eYK-11\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e1370003-76-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular formula\u003c\/td\u003e\n\u003ctd\u003eC25H34O6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e430.5 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInChIKey\u003c\/td\u003e\n\u003ctd\u003eKCQHQCDHFVGNMK-PQUNLUOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e119058028\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eAnimal and metabolism studies\u003c\/h3\u003e\n\u003cp\u003eWork in living animals is recent and sparse, and much of the published in vivo work concerns metabolism for doping control (Piper 2018). One study followed rats for five weeks, with and without swimming exercise, to look for unwanted effects in the brain (Dahleh 2024). Animals given YK-11 retained an aversive memory task less well, showed weaker BDNF signalling in the hippocampus, had a cytokine balance tilted towards inflammation and showed activation of proteins that drive programmed cell death. Exercise offset part of this. One rat study cannot say what happens in people, but its findings point towards harm rather than benefit.\u003c\/p\u003e\n\u003cp\u003eThe cell and animal findings summarised here are not claims about this product.\u003c\/p\u003e\n\u003ch2\u003eYK-11 in the UK: buying, legal status and what to check\u003c\/h2\u003e\n\u003cp\u003eYK-11 is not a licensed medicine in the UK, and it has never been licensed in any other country: it has no MHRA marketing authorisation, is not an authorised food supplement, and cannot lawfully be sold for human consumption. Free Muscle supplies it to adults aged 18 or over for laboratory research only. Because it is a synthetic steroid, its status under the Misuse of Drugs Act is less clear-cut than that of non-steroidal SARMs, and buyers should take their own advice. It is prohibited at all times in sport, as the detection section below explains. Buyers are responsible for the rules that apply to them, including any anti-doping code. Background on the class is in \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eWhat a trustworthy UK listing shows\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eThe compound named precisely, ideally with its CAS number, not a nickname.\u003c\/li\u003e\n\u003cli\u003eA stated strength per capsule and a capsule count, so total content can be worked out.\u003c\/li\u003e\n\u003cli\u003eA batch number on the pack, and a certificate of analysis carrying that number from a named laboratory.\u003c\/li\u003e\n\u003cli\u003eA plain statement when no certificate exists for the batch in stock, instead of a generic PDF.\u003c\/li\u003e\n\u003cli\u003eA named seller, an 18+ restriction, plain packaging and tracked delivery.\u003c\/li\u003e\n\u003cli\u003eNo instructions for human use and no outcome promises.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHow this listing measures up\u003c\/h3\u003e\n\u003cp\u003eThe 10 mg and 60-capsule figures are iMuscle's label claim, not a figure we have assayed. A certificate is shown only where iMuscle supplies one for the batch we hold, and we tell you when there is none. Testing is the real difference from Free Muscle's own-brand \u003ca href=\"\/en-ro\/products\/yk-11-10mg\"\u003eYK-11 10 mg\u003c\/a\u003e, which carries the same label strength and capsule count but is assayed batch by batch at Janoshik Analytical. Orders ship from FreeMuscle's UK operations in Scunthorpe by free tracked UK delivery in plain packaging; orders placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3 to 7 working days, and unopened items can be returned within 30 days (\u003ca href=\"\/en-ro\/pages\/shipping\"\u003edelivery\u003c\/a\u003e, \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e). Our \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e covers each test in more detail.\u003c\/p\u003e\n\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\n\u003cp\u003eYK-11 is offered as capsules, as solutions in dropper bottles and as loose powder, and injectable versions are widely searched for. No study has compared these forms and none has been evaluated in a clinical trial, so the differences below concern what can be measured and kept stable, not effect. This listing is capsules.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eWhat fixes the amount per unit\u003c\/th\u003e\n\u003cth\u003eWhat a certificate can confirm\u003c\/th\u003e\n\u003cth\u003eMain stability concern\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCapsule\u003c\/td\u003e\n\u003ctd\u003eFill weight set at manufacture\u003c\/td\u003e\n\u003ctd\u003eContent per capsule and purity, if finished capsules are tested\u003c\/td\u003e\n\u003ctd\u003eHumidity once the container is opened\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSolution\u003c\/td\u003e\n\u003ctd\u003eConcentration, and whether the compound stays evenly dissolved\u003c\/td\u003e\n\u003ctd\u003eConcentration per millilitre on the test date\u003c\/td\u003e\n\u003ctd\u003eConstant contact with solvent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePowder\u003c\/td\u003e\n\u003ctd\u003eWeighing by the researcher\u003c\/td\u003e\n\u003ctd\u003ePurity of the bulk material\u003c\/td\u003e\n\u003ctd\u003eHumidity and handling losses\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInjectable\u003c\/td\u003e\n\u003ctd\u003eConcentration, carrier and sterility\u003c\/td\u003e\n\u003ctd\u003eUsually concentration only; sterility needs separate testing\u003c\/td\u003e\n\u003ctd\u003eNo published characterisation for YK-11\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eTwo points follow from the chemistry. First, the Cologne anti-doping group described the orthoester-derived group on the D-ring of YK-11 as arguably labile and found no unchanged YK-11 in urine after administration (Piper 2018). Groups that break down readily in the body are also exposed to hydrolysis in a solution containing water or acid, one reason a dry fill is the easier form to store and assay. Second, YK-11 is not a peptide but a small steroid, so the argument that peptides are largely digested when swallowed, discussed in \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides actually work?\u003c\/a\u003e, does not apply. That is a point about chemistry, not a claim about what a capsule does. Fill accuracy is itself a manufacturing variable, which is why the certificate section below asks whether finished capsules or raw powder were tested.\u003c\/p\u003e\n\u003ch2\u003eYK-11 compared with RAD-140\u003c\/h2\u003e\n\u003cp\u003eRAD-140 (testolone) is the compound most often set beside YK-11, and iMuscle sells both in the same format: \u003ca href=\"\/en-ro\/products\/imuscle-testolon-rad-140-60-10mg\"\u003eiMuscle Testolone RAD-140\u003c\/a\u003e is also labelled 10 mg per capsule, 60 capsules. Identical label arithmetic hides two different molecules with very different evidence bases.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint\u003c\/th\u003e\n\u003cth\u003eYK-11\u003c\/th\u003e\n\u003cth\u003eRAD-140\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eChemical class\u003c\/td\u003e\n\u003ctd\u003eSteroid, 19-nor-pregnane derivative\u003c\/td\u003e\n\u003ctd\u003eNon-steroidal SARM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and molecular weight\u003c\/td\u003e\n\u003ctd\u003eC25H34O6, 430.5\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2, 393.8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eAcademic group, Toho University, 2011\u003c\/td\u003e\n\u003ctd\u003ePharmaceutical programme, Radius Health\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAction at the androgen receptor\u003c\/td\u003e\n\u003ctd\u003ePartial agonist in cell assays; induced follistatin in mouse muscle cells\u003c\/td\u003e\n\u003ctd\u003eAgonist designed for tissue selectivity, characterised in rats and monkeys\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublished human data\u003c\/td\u003e\n\u003ctd\u003eNo clinical trial\u003c\/td\u003e\n\u003ctd\u003eOne phase 1 study in 22 women with advanced breast cancer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMain adverse findings\u003c\/td\u003e\n\u003ctd\u003eMemory, inflammatory and cell-death changes in rat hippocampus\u003c\/td\u003e\n\u003ctd\u003eRaised liver enzymes, the most frequent adverse events in the phase 1 study\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK status\u003c\/td\u003e\n\u003ctd\u003eNot a licensed medicine; steroid structure makes its drugs-law status less clear-cut\u003c\/td\u003e\n\u003ctd\u003eNot a licensed medicine; research use only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eSection S1, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eSection S1, prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe evidence gap is the main difference. RAD-140's human data come from one oncology study in patients with advanced disease (LoRusso 2022), yet that study still produced a measured half-life and a documented liver-enzyme signal. YK-11 has neither, so any statement about how it behaves in people rests on nothing published. The regulatory picture differs for a structural reason: a steroid backbone brings YK-11 closer to the anabolic steroids that UK drugs law already controls, whereas RAD-140 is chemically unrelated to them. Neither compound is approved anywhere, both are banned in sport, and nothing here ranks one above the other for any purpose. Brands of RAD-140 are compared on the \u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 collection page\u003c\/a\u003e, and its research is summarised in \u003ca href=\"\/en-ro\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (Testolone): what the research says\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\n\u003cp\u003eiMuscle is a third-party brand, so any certificate of analysis is the manufacturer's, not ours. Where iMuscle supplies a COA for the batch we hold, we show it or send it by email on request; where none exists for the batch in stock, we say so rather than show a generic document. Free Muscle-brand compounds are assayed batch by batch at Janoshik Analytical; that programme does not cover iMuscle. When an iMuscle certificate is available, these are the fields to check.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch or lot number\u003c\/strong\u003e: the same number as the one printed on your pack.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity\u003c\/strong\u003e: the method (HPLC against a YK-11 reference standard, LC-MS, or both) and a result consistent with C25H34O6, molecular weight 430.5. YK-11 has a defined E geometry at its side-chain double bond, and an isomer would share its mass, so a retention-time match to a reference standard is stronger evidence than mass alone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity\u003c\/strong\u003e: the main peak as a percentage of everything the HPLC detected. The remainder may be synthesis by-products or breakdown products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule\u003c\/strong\u003e: the milligrams found in finished capsules, to set against the stated 10 mg; a raw-powder result is not the same measurement.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest date and laboratory\u003c\/strong\u003e: when and by whom the analysis was run.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor this brand, a missing field has a specific meaning. With no certificate for the batch in stock, nothing independent confirms identity, purity or content, and the 10 mg figure stays a label claim. Without a content figure, a certificate confirms what the material is but not the fill; without a batch number, it cannot be tied to your pack; without a named laboratory, it cannot be checked with the lab that issued it. Email us through the \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact page\u003c\/a\u003e with the product name and the batch number on your pack and we will tell you what we hold. See \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e and \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\n\u003cp\u003eYK-11 is prohibited at all times, in and out of competition, under section S1 (anabolic agents) of the WADA Prohibited List, which UK Anti-Doping applies in the UK. Under the strict liability principle of the anti-doping code, an athlete is responsible for any prohibited substance found in their sample, whatever the product label said.\u003c\/p\u003e\n\u003cp\u003eLaboratories can find it. In an elimination study with deuterium-labelled YK-11, the Cologne anti-doping laboratory identified fourteen urinary metabolites and no unchanged YK-11 in urine. Unconjugated metabolites had gone within 24 hours, while glucuronide and sulfate conjugates were still traceable after more than 48 hours, and two glucuronidated metabolites were added to the laboratory's routine screen for anabolic agents (Piper 2018). The study itself was prompted by the detection of YK-11 in a seized black-market product.\u003c\/p\u003e\n\u003cp\u003eThose timings describe how long metabolites were traced in one study; they are not a detection window. With no published human pharmacokinetic study, there is no established half-life for YK-11 in people and the full window is unknown. The reliable statement is that YK-11 is detectable.\u003c\/p\u003e\n\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\n\u003cp\u003eNo stability study of YK-11 capsules has been published, so storage practice rests on general chemistry and the manufacturer's label. Water can cleave the ester and orthoester-derived groups in the molecule, and heat and light degrade most organic research materials.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eKeep the capsules in the original closed container, cool, dry and away from direct sunlight and heat.\u003c\/li\u003e\n\u003cli\u003eClose the lid promptly and leave any desiccant sachet in place; humidity is the main avoidable threat.\u003c\/li\u003e\n\u003cli\u003eKeep the label intact: the batch number links the capsules to any certificate and to any quality query.\u003c\/li\u003e\n\u003cli\u003eRecord the date of receipt and any printed expiry date; without one, a certificate's test date is the only dated reference.\u003c\/li\u003e\n\u003cli\u003eSoft, sticky, discoloured or clumped capsules suggest moisture damage; note the batch number and contact us.\u003c\/li\u003e\n\u003cli\u003eKeep out of reach of children and pets, handle with gloves in a clean area free of food and drink, and dispose of unwanted material under local chemical-waste rules.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIf you might return the item, leave it sealed: returns are accepted within 30 days on unopened items only.\u003c\/p\u003e\n\u003ch2\u003eGlossary\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePartial agonist\u003c\/strong\u003e: a ligand whose maximum effect at a receptor stays below that of a reference hormone; for YK-11 in cell assays the reference was DHT.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDHT (dihydrotestosterone)\u003c\/strong\u003e: a potent androgen made from testosterone in tissues such as skin and prostate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e19-nor steroid\u003c\/strong\u003e: a steroid missing the carbon atom usually found at position 19, the skeleton YK-11 shares with nandrolone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFollistatin\u003c\/strong\u003e: a glycoprotein that captures myostatin and activin outside the cell; the 2013 C2C12 study reported a rise in its expression, the basis of the myostatin-inhibitor label.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eC2C12 cells\u003c\/strong\u003e: a mouse muscle precursor line that fuses into muscle-like fibres in culture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHydrolysis\u003c\/strong\u003e: cleavage of a chemical bond by water, the main storage risk for the ester and orthoester-derived groups in YK-11.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLabel claim\u003c\/strong\u003e: the amount a manufacturer prints per capsule, here 10 mg, unconfirmed until a content assay is run.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetention time\u003c\/strong\u003e: how long a compound takes to pass through an HPLC column, compared against a reference standard to support identity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConjugated metabolite\u003c\/strong\u003e: a breakdown product linked to glucuronic acid or sulfate for excretion; these were the longest-traced YK-11 markers in the Cologne study.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAbout iMuscle YK-11\u003c\/h2\u003e\u003cp\u003eThe YK-11 pot from iMuscle has a red label with YK 11 in the centre and the iMUSCLE mark on its black panel above. Its front box states 60 capsules, 10 mg each; the side panel gives 10 mg of YK 11 per capsule, the compound's systematic name as a methyl ester, and iMuscle's line claiming purity tested above 97%. The brand's Romanian site lists the pot as YK 11, \"60\/10mg\".\u003c\/p\u003e\u003cp\u003eiMuscle's About page explains its testing policy in its own terms: because SARMs are unregulated and raw material need not meet any standard, it says it tests all lots at an independent European laboratory; the quality page adds a 97% purity minimum for raw material. Those are the brand's statements. YK-11 also features in two iMuscle stacks we list, \u003ca href=\"\/en-ro\/products\/imuscle-testolon-yk11-ibutamoren\"\u003eTestolon, YK-11 and Ibutamoren\u003c\/a\u003e and \u003ca href=\"\/en-ro\/products\/imuscle-ligandrol-testolon-yk-11\"\u003eLigandrol, Testolon and YK-11\u003c\/a\u003e; the rest of the range is on the \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle brand page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eUnlike the SARMs it is sold beside, YK-11 has a steroid skeleton. Its literature is mostly cell work published since 2011, with a few rat studies, and it has never been tested in people; its steroid structure leaves its UK legal position less settled than that of the non-steroidal SARMs, and WADA bans it under S1. Free Muscle also sells a 10 mg, 60-capsule YK-11 under its own brand, with each batch assayed at Janoshik Analytical; both appear on the \u003ca href=\"\/en-ro\/collections\/yk-11\"\u003eYK-11 collection\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eThe gallery shows protocol RN18695 from 2021, which has no lot number, alongside an HPLC print-out for YK11 with lot 20210911. Neither is tied to the pots in stock now. Check your pot for a lot or batch code and, if one is printed, \u003ca href=\"\/en-ro\/pages\/contact\"\u003esend it to us\u003c\/a\u003e; we will pass on any certificate iMuscle provides for that lot, or tell you plainly that there is none.\u003c\/p\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/yk-11\"\u003eAll brands of YK-11\u003c\/a\u003e, compared on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/yk-11-what-is-known\"\u003eYK-11: a steroidal compound sold as a SARM, what is actually known\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 (testolone)\u003c\/a\u003e and the full \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eSARMs range\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eKanno Y, et al. (17alpha,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11) is a partial agonist of the androgen receptor. Biol Pharm Bull. 2011;34(3):318-23. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21372378\/\" rel=\"noopener\"\u003ePMID: 21372378\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eKanno Y, et al. Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression. Biol Pharm Bull. 2013;36(9):1460-5. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23995658\/\" rel=\"noopener\"\u003ePMID: 23995658\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003ePiper T, et al. Studies on the in vivo metabolism of the SARM YK11: Identification and characterization of metabolites potentially useful for doping controls. Drug Test Anal. 2018;10(11-12):1646-56. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30379415\/\" rel=\"noopener\"\u003ePMID: 30379415\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eDahleh MMM, et al. From gains to gaps? How Selective Androgen Receptor Modulator (SARM) YK11 impact hippocampal function: In silico, in vivo, and ex vivo perspectives. Chem Biol Interact. 2024;394:110971. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38521455\/\" rel=\"noopener\"\u003ePMID: 38521455\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34565686\/\" rel=\"noopener\"\u003ePMID: 34565686\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468980400354,"sku":null,"price":42.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/YK11_720x_d356e17a-105c-480a-834b-d0c2826f4875.jpg?v=1789931421"},{"product_id":"thoroughbred-labs-gw501516","title":"Thoroughbred Labs Cardarine GW-501516","description":"\u003cp\u003e\u003cstrong\u003eThoroughbred Labs Cardarine GW-501516\u003c\/strong\u003e is a Thoroughbred Labs listing of Cardarine, supplied as 60 capsules per pack, and Thoroughbred Labs prints 10 mg per capsule on the side panel of the tub, a figure its own product title repeats. It is supplied through the \u003ca href=\"\/en-ro\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e range for laboratory research only, is not for human consumption, and is sold to adults aged 18 and over. This page sets out what the published research on Cardarine reports, what the label documents, where the compound stands in UK law and in sport, and how batch certificates are handled for Thoroughbred Labs products.\u003c\/p\u003e\n\u003ch2\u003eAbout Cardarine\u003c\/h2\u003e\n\u003cp\u003eCardarine, also written GW-501516, GW501516, GW1516 or endurobol, is a synthetic agonist of PPAR-delta, a nuclear receptor that regulates genes involved in fatty acid oxidation in skeletal muscle. It was developed by GlaxoSmithKline and Ligand as a candidate for lipid disorders. It is not a SARM, although it is often sold alongside them, and it is not a peptide either: it is a small synthetic molecule built around a thiazole ring.\u003c\/p\u003e\n\u003cp\u003ePubChem lists it as CID 9803963, CAS number 317318-70-0, molecular formula C21H18F3NO3S2, molecular weight 453.5 and InChIKey YDBLKRPLXZNVNB-UHFFFAOYSA-N. The systematic name, 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid, contains a sulphur atom in a thioether link; that sulphur is where the body oxidises the molecule, which matters for drug testing (see below).\u003c\/p\u003e\n\u003ch2\u003eWhat the published research reports\u003c\/h2\u003e\n\u003cp\u003eIn a 2008 study in mice, GW-501516 given alongside treadmill training increased running endurance compared with training alone, which led the authors to describe the compound as an exercise mimetic; without training it produced no endurance change in that study (Narkar et al., 2008). A 2012 trial in 268 people with low HDL cholesterol reported that, compared with baseline, HDL rose and LDL cholesterol and triglycerides fell over twelve weeks (Olson et al., 2012); the trial was short and not designed to assess long-term safety. Development was abandoned in 2007 after two-year carcinogenicity studies in rats and mice found tumours in multiple organs. Those toxicology results were presented at a conference and are not indexed on PubMed, so they are not cited here, but they are the most important fact about this compound. Nothing in this section is a claim about this product.\u003c\/p\u003e\n\u003ch2\u003eThis listing\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eManufacturer: Thoroughbred Labs\u003c\/li\u003e\n\u003cli\u003eCompound: Cardarine (GW-501516)\u003c\/li\u003e\n\u003cli\u003eForm: Capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStrength: 10 mg per capsule, the figure Thoroughbred Labs prints on the FACTS panel; 600 mg per tub as labelled\u003c\/li\u003e\n\u003cli\u003eBatch certificate of analysis: shown where Thoroughbred Labs supplies one for the batch we hold\u003c\/li\u003e\n\u003cli\u003eSold for laboratory research to adults aged 18 and over; not for human consumption\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSearches such as \"cardarine 10mg\" and \"cardarine 20mg UK\" ask for a figure per capsule. This pack is the 10 mg one: the panel states 10 mg, so the tub holds 600 mg as labelled, and that stated total is what can be set beside other listings. Our guide to \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003ecomparing by price per milligram\u003c\/a\u003e explains why that matters when setting listings side by side.\u003c\/p\u003e\n\u003ch2\u003eCardarine in the UK: buying, legal status and what to check\u003c\/h2\u003e\n\u003cp\u003ePeople searching \"cardarine UK legal\", \"cardarine UK buy\" or \"UK sarms cardarine\" usually want two answers: whether a purchase is lawful, and whether a particular seller can be trusted. On the first, Cardarine is not a licensed medicine in the UK, has not been assessed by the MHRA, and is not an authorised food supplement. It is not listed as a controlled drug. This listing is offered only to adults aged 18 and over for laboratory research, not for human consumption. A seller who gives instructions for taking it, or describes what it will do for the buyer, is wrongly presenting it as a medicine or supplement.\u003c\/p\u003e\n\u003cp\u003eIn sport, GW-501516 is named on the WADA Prohibited List under section S4 (hormone and metabolic modulators) as a PPAR-delta agonist and is prohibited at all times. WADA issued a specific warning about it in 2013. Anyone subject to anti-doping rules should consult the current list. Our \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eresearch guide\u003c\/a\u003e covers the wider legal picture for compounds sold alongside SARMs.\u003c\/p\u003e\n\u003cp\u003eOn trust, star ratings and forum threads (the \"cardarine UK reviews\" and \"cardarine reddit\" searches) cannot tell you what is in a capsule. Documents can. A UK listing worth relying on should show:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eThe manufacturer's name and the compound's identifiers, so any certificate can be matched to GW-501516 rather than something similar. Here: Thoroughbred Labs, with CAS 317318-70-0 given above.\u003c\/li\u003e\n\u003cli\u003eA stated strength and capsule count. Here: 60 capsules at a stated 10 mg each, printed on the tub's side FACTS panel and repeated in the brand's own product title.\u003c\/li\u003e\n\u003cli\u003eA certificate for the batch actually in stock, carrying a batch number. Here: shown only where Thoroughbred Labs supplies one for the batch we hold.\u003c\/li\u003e\n\u003cli\u003eAn identifiable seller with an age requirement and a returns route. Here: FreeMuscle, a business registered in Andorra with UK operations and dispatch in Scunthorpe, selling to adults aged 18 and over, with 30-day returns on unopened items.\u003c\/li\u003e\n\u003cli\u003eTracked delivery in plain packaging. Here: free tracked UK delivery on every order in plain packaging, orders placed before 2pm Monday to Friday processed the same working day, and EU delivery in 3-7 working days.\u003c\/li\u003e\n\u003cli\u003eNo usage instructions of any kind. Here: none given.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eDelivery and returns terms are on our \u003ca href=\"\/en-ro\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages. To see the brands of this compound we hold side by side, use the \u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eCardarine collection\u003c\/a\u003e. Our \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e applies the same questions to any shop.\u003c\/p\u003e\n\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\n\u003cp\u003eThoroughbred Labs is a third-party brand in the Muscle Market range, so the testing position differs from our own label. Every Free Muscle-brand batch is assayed by Janoshik Analytical, an independent laboratory, with the certificate sent on request by email. For Thoroughbred Labs products we show a certificate of analysis only where the manufacturer supplies one for the specific batch we hold. A generic PDF with no batch number is not a batch certificate, and we do not present one as such. Email us with the product name and we will send what we hold, or say plainly that there is none.\u003c\/p\u003e\n\u003cp\u003eWhen a certificate for this product is available, these are the fields to check:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound name and identity method\u003c\/strong\u003e: the document should name GW-501516 and say how identity was established. HPLC matches the retention time of the sample against a reference standard; LC-MS adds a molecular mass, which for this compound should be consistent with the 453.5 molecular weight above.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity\u003c\/strong\u003e: a percentage, normally from HPLC peak areas, showing how much of what was detected is the named compound. It says nothing about how much compound each capsule holds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule\u003c\/strong\u003e: the measured milligrams of GW-501516 in one capsule. That is the number to compare with the 10 mg the panel states.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch or lot number\u003c\/strong\u003e: must match the code printed on the pack in your hands.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest date and laboratory name\u003c\/strong\u003e: tie the result to a specific analysis of current stock.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWhat a missing field means for this brand: no certificate at all means this listing makes no claim about identity, purity or content; a certificate with purity but no content confirms the molecule without telling you the amount per capsule; a batch number that differs from your pack means the document describes other stock. Our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests page\u003c\/a\u003e and the article on \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e go further, and you can \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e with any mismatch.\u003c\/p\u003e\n\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\n\u003cp\u003eCardarine is sold by other sellers as capsules, tablets and liquid suspensions or solutions. The molecule is the same in each; what differs is how the amount per unit is fixed and what can go wrong on the way. No published study compares these formats for GW-501516, so the points below come from general pharmaceutical practice rather than compound-specific data.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsules\u003c\/strong\u003e hold a weighed powder fill, usually blended with an inert filler. Errors come from uneven blending or variable fill weight. Each capsule is a discrete unit a laboratory can assay, so content per capsule can be measured directly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquids\u003c\/strong\u003e carry a stated concentration in a solvent that is not always named. The compound has to stay dissolved or evenly suspended, and the amount in any measured volume depends on that as well as on measuring accuracy. A certificate confirms concentration on the test date only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePowders\u003c\/strong\u003e sold loose require the researcher to weigh every portion, which moves the accuracy question onto the laboratory's own balance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe \"cardarine peptide\" search reflects a common mix-up. Peptides are chains of amino acids that digestive enzymes break apart, which is why research on giving them by mouth is contested (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides work?\u003c\/a\u003e). GW-501516 has no amino acid chain; it is a small organic molecule, and the human lipid trial cited above used oral administration. That is a statement about the chemistry and the trial design, not about this product. For this pack, the practical value of the capsule format depends on a certificate that reports measured content against the stated 10 mg.\u003c\/p\u003e\n\u003ch2\u003eCardarine compared with SR9009 (stenabolic)\u003c\/h2\u003e\n\u003cp\u003e\"Stenabolic vs cardarine\" is the comparison people search most for this compound, because sellers list the two side by side for similar purposes. Pharmacologically they have little in common. GW-501516 activates PPAR-delta; SR9009 was described in a 2012 paper from the Scripps Research Institute as a synthetic agonist of REV-ERB-alpha and REV-ERB-beta, nuclear receptors that help drive the daily rhythm of clock genes (Solt et al., 2012). In that study, SR9009 was given to mice by intraperitoneal injection; the mice showed altered circadian activity and changes in metabolic gene expression, and diet-induced obese mice lost more fat mass than controls. The authors noted that handling and twice-daily injections themselves caused weight loss in the control animals.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint of comparison\u003c\/th\u003e\n\u003cth\u003eCardarine (GW-501516)\u003c\/th\u003e\n\u003cth\u003eSR9009 (stenabolic)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTarget\u003c\/td\u003e\n\u003ctd\u003ePPAR-delta agonist\u003c\/td\u003e\n\u003ctd\u003eREV-ERB-alpha and REV-ERB-beta agonist\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIdentifiers\u003c\/td\u003e\n\u003ctd\u003eCAS 317318-70-0; C21H18F3NO3S2\u003c\/td\u003e\n\u003ctd\u003eCAS 1379686-30-2; C20H24ClN3O4S\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eGlaxoSmithKline and Ligand, lipid disorder programme\u003c\/td\u003e\n\u003ctd\u003eAcademic research compound, Scripps Research Institute\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman data\u003c\/td\u003e\n\u003ctd\u003ePhase II lipid trials; development stopped in 2007 after rodent carcinogenicity findings\u003c\/td\u003e\n\u003ctd\u003eNo published human trial\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMain published evidence\u003c\/td\u003e\n\u003ctd\u003eMouse endurance study; human lipid trial\u003c\/td\u003e\n\u003ctd\u003eMouse studies using injection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK status\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only, 18+\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only, 18+\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eS4 metabolic modulator, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eS4 metabolic modulator, prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eNeither compound is a SARM, and neither has ever been approved as a medicine. Cardarine has the larger human evidence base but also the toxicology finding that ended its development; SR9009 has no human trial at all, so statements about its effects in people rest on anecdote. We make no claim about either in combination with anything else. The \u003ca href=\"\/en-ro\/collections\/sr9009\"\u003eSR9009 collection\u003c\/a\u003e lists the brands we stock, and our \u003ca href=\"\/en-ro\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 research guide\u003c\/a\u003e covers the 2012 work in more detail.\u003c\/p\u003e\n\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\n\u003cp\u003eGW-501516 has been on the WADA Prohibited List since January 2009, when it was first categorised under gene doping; it now sits in section S4 among metabolic modulators and is banned both in and out of competition. Under the strict liability principle an athlete is responsible for any prohibited substance found in a sample, including one from a mislabelled or contaminated product.\u003c\/p\u003e\n\u003cp\u003eAnti-doping laboratories do not rely only on the parent molecule. A 2010 study from the German Sport University Cologne identified two major urinary metabolites, the sulfoxide and the sulfone formed by oxidation of that thioether sulphur, and validated a routine urine screening method with a limit of detection of 0.1 ng\/ml (Thevis et al., 2010). The paper established what to look for and how sensitively; it did not measure how long after exposure the compound or its metabolites remain detectable. For this capsule product the answer is therefore: detectable, window not established. Our article on \u003ca href=\"\/en-ro\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003ewhy Cardarine development stopped\u003c\/a\u003e covers the history behind the ban.\u003c\/p\u003e\n\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\n\u003cp\u003eWe know of no published study on how GW-501516 keeps in capsule form, so the expiry date, where Thoroughbred Labs prints one, is the only product-specific guide. General good practice applies. Store the sealed container somewhere cool and dry, away from direct sunlight and heat sources. Gelatine and plant-based capsule shells both react to humidity: damp air softens them and can let moisture reach the powder, and very dry air can make them brittle.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eKeep capsules in the original container, which carries the batch number that links them to any certificate.\u003c\/li\u003e\n\u003cli\u003eRecord the date received, the date first opened and the batch number in your laboratory log.\u003c\/li\u003e\n\u003cli\u003eHandle capsules and any spilled powder with nitrile gloves.\u003c\/li\u003e\n\u003cli\u003eDispose of expired or surplus material through your organisation's chemical waste route, not household waste.\u003c\/li\u003e\n\u003cli\u003eKeep out of reach of children and pets, and apart from food and drink.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eGlossary\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePPAR-delta\u003c\/strong\u003e: peroxisome proliferator-activated receptor delta, a nuclear receptor that switches on genes for fatty acid use; GW-501516 activates it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNuclear receptor\u003c\/strong\u003e: a protein inside the cell that binds a molecule and then changes which genes are read.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAgonist\u003c\/strong\u003e: a compound that binds a receptor and activates it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExercise mimetic\u003c\/strong\u003e: a label researchers gave compounds that reproduced some molecular effects of training in animals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eREV-ERB\u003c\/strong\u003e: a pair of nuclear receptors in the body's clock machinery; SR9009 was designed to activate them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCarcinogenicity study\u003c\/strong\u003e: a long-term animal study, often two years in rodents, run to see whether a drug candidate causes tumours.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHDL cholesterol\u003c\/strong\u003e: high-density lipoprotein cholesterol, the blood lipid measure the 2012 GW-501516 trial tracked.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolite\u003c\/strong\u003e: a compound the body produces by chemically altering a substance; anti-doping tests for GW-501516 target its sulfoxide and sulfone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLimit of detection\u003c\/strong\u003e: the smallest amount per millilitre of urine that a validated screening method picks up consistently, 0.1 ng\/ml in the 2010 GW-501516 method.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: under the World Anti-Doping Code, a positive sample is the athlete's responsibility whether the substance came from a deliberate choice or a contaminated product.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAbout Thoroughbred Labs Cardarine GW-501516\u003c\/h2\u003e\n\u003cp\u003eThe Thoroughbred Labs name belongs to a UK online shop, thoroughbredlabs.co.uk, whose footer names 24\/7 Billing Limited, registered company 14990140, for statutory purposes, a company Companies House records as active with a London registered office and a July 2023 incorporation date. The brand's terms require buyers to be 18 or over, limit everything it sells to research use and state that its products carry no licence from the MHRA or any other regulator.\u003c\/p\u003e\n\u003cp\u003eThis tub reads GW501516 in large type with CARDARINE beneath it and 60 CAPSULES; the FACTS panel on the side states GW501516 10mg per capsule, the other ingredients listed as microcrystalline cellulose plus magnesium stearate, in a vegetarian capsule, so the tub carries 600 mg as labelled. The brand's own product title, GW501516 10mg 60 Capsules, states the same figure. What the brand has not published is any analysis of these capsules: its certificate page, checked on 2 October 2026, carries reports for its BPC157, SLU-PP-332 and MK677 capsules but none for GW501516, so this listing shows no certificate and claims nothing about identity, purity or content for the batch held.\u003c\/p\u003e\n\u003cp\u003eWithin the range, GW501516 is sold only as capsules, unlike the brand's peptides, which it also offers as vials. Among the Cardarine brands we stock, \u003ca href=\"\/en-ro\/products\/imuscle-cardarine-gw501516-60-10mg\"\u003eiMuscle\u003c\/a\u003e states the same 10 mg per capsule, and Free Muscle's own packs are labelled 5 mg and 10 mg, every batch carrying a Janoshik certificate; the \u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eCardarine collection\u003c\/a\u003e lays them out, and the \u003ca href=\"\/en-ro\/collections\/brand-thoroughbred-labs\"\u003eThoroughbred Labs collection\u003c\/a\u003e covers the brand's labelling and published documents. Check the seal and the batch number on arrival and ask us what exists for that batch.\u003c\/p\u003e\n\u003cp\u003eAs a compound, GW-501516 is a PPAR-delta agonist whose pharmaceutical development stopped in 2007 after rodent carcinogenicity findings; it has never been licensed anywhere, is neither a medicine nor a food in UK law, and WADA names it under S4 as a metabolic modulator, prohibited at all times. Supplied to adults for laboratory research only.\u003c\/p\u003e\n\u003ch2\u003eRelated\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eAll brands of Cardarine we stock, compared\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/collections\/brand-thoroughbred-labs\"\u003eAll Thoroughbred Labs products\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/sr9009\"\u003eSR9009 (stenabolic)\u003c\/a\u003e and the wider \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eSARMs range\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003eCardarine (GW-501516): why development stopped and what the data show\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003eBatch testing and certificates of analysis\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice. Summaries of published research describe study findings and are not claims about any product.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eNarkar VA, et al. AMPK and PPARdelta agonists are exercise mimetics. Cell. 2008;134(3):405-15. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18674809\/\" rel=\"noopener\"\u003ePMID: 18674809\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eOlson EJ, et al. Lipid effects of peroxisome proliferator-activated receptor-delta agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Arterioscler Thromb Vasc Biol. 2012;32(9):2289-94. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22814748\/\" rel=\"noopener\"\u003ePMID: 22814748\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eThevis M, et al. Characterization of two major urinary metabolites of the PPARdelta-agonist GW1516 and implementation of the drug in routine doping controls. Anal Bioanal Chem. 2010;396(7):2479-91. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19946680\/\" rel=\"noopener\"\u003ePMID: 19946680\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eSolt LA, et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature. 2012;485(7396):62-8. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22460951\/\" rel=\"noopener\"\u003ePMID: 22460951\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Thoroughbred Labs","offers":[{"title":"Default Title","offer_id":48468980498658,"sku":null,"price":29.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/GW_5f1c6cba-b556-477b-8932-314ca6a20254.png?v=1789931426"},{"product_id":"thoroughbred-labs-rad140","title":"Thoroughbred Labs RAD-140","description":"\u003cp\u003eThoroughbred Labs RAD-140 is a 60-capsule pack of RAD-140 (testolone), a non-steroidal SARM, produced by Thoroughbred Labs and stocked by Free Muscle through \u003ca href=\"\/en-ro\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e. The brand's own product text names it only as RAD140 capsules, but the FACTS panel on the side of the tub states 10 mg per capsule, so this listing records 10 mg, or 600 mg per tub, as stated by Thoroughbred Labs. This listing is for laboratory research by adults aged 18 and over, and nothing here is guidance on use.\u003c\/p\u003e\u003ch2\u003eAbout RAD-140\u003c\/h2\u003e\u003cp\u003eRAD-140 (testolone) belongs to the SARM class: non-steroidal molecules that act as ligands at the androgen receptor. The molecule was first described in a 2011 paper from Radius Health, which described it as a potent, orally bioavailable, non-steroidal SARM and reported its characterisation in several preclinical models of anabolic androgen action (Miller et al., 2011). Those models were animal experiments, not human studies.\u003c\/p\u003e\u003cp\u003ePubChem records it under CAS number 1182367-47-0, formula C20H16ClN5O2, molecular weight 393.8 and InChIKey XMBUPPIEVAFYHO-KPZWWZAWSA-N. The systematic name, 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile, shows two defined stereocentres and no steroid ring system, and vosilasarm is listed among its synonyms.\u003c\/p\u003e\u003cp\u003eThe only published human trial is a Phase 1 dose-finding study in patients with hormone-receptor-positive metastatic breast cancer, reported in 2022 (LoRusso et al., 2022). Raised AST, ALT and bilirubin were among the most frequent adverse events, grade 3 or 4 adverse events occurred in 16 of the 22 patients, and the investigators identified a maximum tolerated dose. Two blood markers moved as expected for an androgen: sex hormone-binding globulin fell in every one of the 18 women tested and prostate-specific antigen rose in 16 of 20, which the investigators took as evidence that the receptor was engaged. The trial assessed tolerability and tumour response, not muscle or strength. Outside trials, case reports describe cholestatic liver injury in people who had taken products sold as RAD-140 (Leung et al., 2022), and hypogonadism in a man whose supplements contained RAD-140 together with other undeclared substances, so no single compound could be blamed (Chong et al., 2024). The findings summarised here describe the compound in research settings and are not claims about this product.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCompound: RAD-140 (Testolone)\u003c\/li\u003e\n\u003cli\u003eBrand: Thoroughbred Labs\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: 10 mg, as printed on the FACTS panel on the side of the tub\u003c\/li\u003e\n\u003cli\u003eTotal per pack: 600 mg (10 mg x 60), as labelled\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAt a stated 10 mg per capsule this tub holds 600 mg as labelled, the same stated total as the other RAD-140 packs we stock, so comparison comes down to documentation and fillers. The figure is a label claim; a batch certificate, where Thoroughbred Labs supplies one, is what would confirm measured content. See \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003ehow to compare by milligram\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eRAD-140 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eMost UK searches for this compound, \"RAD 140 UK sale\" and \"testolone RAD 140 UK\" among them, come down to whether it can be bought lawfully and whether a given listing deserves trust. The legal answer is narrow. RAD-140 has no MHRA marketing authorisation, so it is not a licensed medicine in the UK; it is not an authorised food supplement; and it therefore cannot lawfully be sold for human consumption. Free Muscle sells it to adults aged 18 or over for laboratory research only. WADA prohibits it at all times under section S1 (anabolic agents), and buyers are responsible for the rules that apply to them, including any anti-doping code. The class as a whole is covered in \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eTrust matters because labels in this market have a poor record. Of 44 products bought online as SARMs in 2016 and analysed with WADA-approved procedures, only 23 (52 per cent) contained a SARM, 4 contained no active compound, 11 contained substances not on the label, and the measured amount matched the label in just 18 (41 per cent) (Van Wagoner et al., 2017). Those products came from other sellers, so the figures show the scale of the problem, not the contents of any particular pack. The table shows what a checkable listing includes.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eWhat to look for\u003c\/th\u003e\n\u003cth\u003eWhy it matters\u003c\/th\u003e\n\u003cth\u003eThis listing\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eNamed manufacturer and compound identifiers\u003c\/td\u003e\n\u003ctd\u003eA certificate can be matched to the right molecule\u003c\/td\u003e\n\u003ctd\u003eThoroughbred Labs; CAS number given above\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStated strength and capsule count\u003c\/td\u003e\n\u003ctd\u003eTotal content per pack can be worked out\u003c\/td\u003e\n\u003ctd\u003e60 capsules; 10 mg per capsule stated on the FACTS panel\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCertificate for the batch in stock\u003c\/td\u003e\n\u003ctd\u003eA generic document says nothing about your pack\u003c\/td\u003e\n\u003ctd\u003eShown only where Thoroughbred Labs supplies one for the batch we hold\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAccountable UK seller\u003c\/td\u003e\n\u003ctd\u003eSomeone to contact, an age check and a returns route\u003c\/td\u003e\n\u003ctd\u003eFreeMuscle, registered in Andorra, dispatching from Scunthorpe; 18+ only; unopened items returnable within 30 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTracked delivery in plain packaging\u003c\/td\u003e\n\u003ctd\u003eThe parcel can be followed and does not advertise its contents\u003c\/td\u003e\n\u003ctd\u003eFree tracked UK delivery in plain packaging on every order; EU delivery 3-7 working days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNo instructions for human use\u003c\/td\u003e\n\u003ctd\u003eA research compound cannot also be sold for consumption\u003c\/td\u003e\n\u003ctd\u003eNone given\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eOrders placed before 2pm Monday to Friday are processed the same working day; details are on our \u003ca href=\"\/en-ro\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages. The \u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 collection\u003c\/a\u003e sets the brands we stock side by side on stated strength and documentation, and our \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e applies the same tests to any shop.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eAny certificate of analysis for this product comes from Thoroughbred Labs, not from Free Muscle. Our policy for third-party brands is simple: we show a COA where the manufacturer supplies one for the batch we hold, and not otherwise. Email us to ask what documentation exists for the current batch before ordering. Free Muscle-brand compounds are batch-tested by the independent laboratory Janoshik Analytical; Thoroughbred Labs products are not in that programme. Where a certificate exists, read it field by field.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity\u003c\/strong\u003e: is the substance RAD-140? High-performance liquid chromatography (HPLC) compares its retention time with a reference standard; liquid chromatography with mass spectrometry (LC-MS) also measures molecular mass, and RAD-140 gives a protonated ion at m\/z 394 (Wagener et al., 2022). The compound named should match the CAS number and formula above.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity\u003c\/strong\u003e: a percentage, usually calculated from HPLC peak areas, stating how much of the material detected is RAD-140 rather than impurities. A high purity figure can sit alongside any quantity of compound per capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule\u003c\/strong\u003e: milligrams of RAD-140 actually found in a capsule. It is the only way to check the 10 mg the panel states against what a capsule actually holds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch or lot number\u003c\/strong\u003e: the code on the certificate and the code on your pack should be identical.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest date and laboratory\u003c\/strong\u003e: show when and by whom the batch was analysed; an undated document cannot be tied to current stock.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThree gaps are common with third-party stock. If Thoroughbred Labs has supplied no certificate for the batch we hold, this listing makes no claim about identity, purity or content. If a certificate reports purity without content, it confirms the molecule but leaves the quantity per capsule unknown. If its batch number differs from the one on your pack, it describes other stock. See \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e and \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e, and \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e if anything does not match.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eOther sellers offer RAD-140 as tablets or liquids, which is what searches for \"RAD 140 tablets UK\" and \"RAD 140 liquid UK\" reflect. Changing the format leaves the compound untouched but changes three practical things: how the quantity in each unit is set, where errors creep in, and what a batch analysis can prove. No published work compares the formats for RAD-140, so the table reflects general pharmaceutical practice.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eHow the amount per unit is set\u003c\/th\u003e\n\u003cth\u003eMain sources of error\u003c\/th\u003e\n\u003cth\u003eWhat a batch certificate can confirm\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCapsule\u003c\/td\u003e\n\u003ctd\u003eA measured powder fill, usually blended with a filler\u003c\/td\u003e\n\u003ctd\u003eUneven blending; variation in fill weight\u003c\/td\u003e\n\u003ctd\u003eIdentity, purity and content per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTablet\u003c\/td\u003e\n\u003ctd\u003eA powder blend compressed with binders\u003c\/td\u003e\n\u003ctd\u003eBlend uniformity; losses during compression and coating\u003c\/td\u003e\n\u003ctd\u003eIdentity, purity and content per tablet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLiquid\u003c\/td\u003e\n\u003ctd\u003eA stated concentration in a solvent, measured by volume\u003c\/td\u003e\n\u003ctd\u003eSolubility and stability in the solvent; accuracy of volume; solvent not always named\u003c\/td\u003e\n\u003ctd\u003eIdentity and concentration on the test date only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003ePeptides are amino acid chains that digestive enzymes break down, which is why research on peptides given by mouth is contested (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides work?\u003c\/a\u003e). RAD-140 has no such chain: it is a small heterocyclic molecule that its discoverers reported as orally bioavailable in animal models (Miller et al., 2011), a point of chemistry rather than a claim about this product. For this pack, the capsule's advantage as a discrete unit a laboratory can assay is realised only when a certificate reports measured content per capsule against the 10 mg stated on the panel.\u003c\/p\u003e\u003ch2\u003eRAD-140 compared with RAD-150 (TLB-150)\u003c\/h2\u003e\u003cp\u003eAmong comparison searches for this compound, \"RAD 140 vs RAD 150\" leads, with \"TLB 150 vs RAD 140\" asking the same thing under another name. RAD-150 is sold as the benzoate ester of RAD-140: the same core molecule with a benzoic acid group joined through an ester bond to its single hydroxyl group. Sellers present the ester as longer-acting, an idea borrowed from injectable testosterone esters that has not been tested for RAD-150 in any published study.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint of comparison\u003c\/th\u003e\n\u003cth\u003eRAD-140 (testolone)\u003c\/th\u003e\n\u003cth\u003eRAD-150 (TLB-150)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eWhat it is\u003c\/td\u003e\n\u003ctd\u003eNon-steroidal SARM, CAS 1182367-47-0\u003c\/td\u003e\n\u003ctd\u003eDescribed as the benzoate ester of RAD-140\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMechanism\u003c\/td\u003e\n\u003ctd\u003eAndrogen receptor agonist\u003c\/td\u003e\n\u003ctd\u003eNot studied; conversion to RAD-140 never measured\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubMed-indexed research\u003c\/td\u003e\n\u003ctd\u003e2011 discovery paper, a phase 1 cancer trial, anti-doping excretion work and liver injury case reports\u003c\/td\u003e\n\u003ctd\u003eNo relevant records in a search on 26 September 2026\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman data\u003c\/td\u003e\n\u003ctd\u003ePhase 1 trial in 22 women with breast cancer; excretion studies in adult men\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK status\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only, 18+\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research use only, 18+\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eNamed under S1.2, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eNot named, but S1.2 is not a closed list\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBrands we stock\u003c\/td\u003e\n\u003ctd\u003eFree Muscle, iMuscle, Yakka Strength, Thoroughbred Labs\u003c\/td\u003e\n\u003ctd\u003eFree Muscle only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eAn ester adds mass, so a milligram of RAD-150 contains less than a milligram of the RAD-140 core, and label strengths of the two are not interchangeable. Every statement about RAD-150's activity, timing or adverse effects is inferred from RAD-140 or from anecdote. We do not stock a Thoroughbred Labs RAD-150; the \u003ca href=\"\/en-ro\/collections\/rad-150\"\u003eRAD-150 collection\u003c\/a\u003e lists the brand we hold, and \u003ca href=\"\/en-ro\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150 (TLB-150)\u003c\/a\u003e covers the ester chemistry in more depth.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eIn sport the position is unambiguous. The WADA Prohibited List bans RAD-140 in and out of competition and names it among the examples in S1.2, other anabolic agents, so it would be expected to trigger a positive test in any tested sport. Every S1 substance is non-specified under the World Anti-Doping Code, which bears on sanctions, and athletes are strictly liable for their samples whether a finding came from deliberate use or a contaminated product.\u003c\/p\u003e\u003cp\u003eDetection times have been measured, though only after tiny exposures. A doping-control team at the German Sport University Cologne gave RAD-140 to adult male volunteers in six excretion studies of five people each and followed their urine by high-resolution LC-MS\/MS (Wagener et al., 2022). For the three single-application arms, the last sample still containing unchanged RAD-140 came at:\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eSingle amount given in the study\u003c\/th\u003e\n\u003cth\u003eLast detection of unchanged RAD-140 in urine\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e1 microgram\u003c\/td\u003e\n\u003ctd\u003e212 hours (almost 9 days)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e10 micrograms\u003c\/td\u003e\n\u003ctd\u003e240 hours (10 days)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e50 micrograms\u003c\/td\u003e\n\u003ctd\u003e696 hours (29 days)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eNothing above 50 micrograms was tested, and the authors noted that studies with larger amounts are still needed, so these times cannot be read as the longest possible window. For a capsule product the position is: detectable, window not established.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eThoroughbred Labs' packaging is the only source for an expiry date, where one is printed, and we know of no published study of RAD-140's stability in capsules. Keep the container sealed in a cool, dry place, out of direct light and away from heat such as radiators or sunny windowsills. Capsule shells respond to humidity in both directions: damp air makes gelatine tacky, so capsules cling together and moisture can reach the fill, while very dry storage can leave shells cracked.\u003c\/p\u003e\u003cp\u003eGood laboratory practice for this pack:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eLeave capsules in the manufacturer's container. The batch number printed on it is the only link between the capsules and any certificate.\u003c\/li\u003e\n\u003cli\u003eMark the dates of receipt and first opening on the label, and enter the batch in your lab records.\u003c\/li\u003e\n\u003cli\u003eWear nitrile gloves when handling capsules or their contents.\u003c\/li\u003e\n\u003cli\u003eSend surplus or expired material for disposal through your organisation's chemical waste arrangements.\u003c\/li\u003e\n\u003cli\u003eStore out of reach of children and animals, away from food and drink.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAndrogen receptor agonist\u003c\/strong\u003e: a compound that binds the androgen receptor and activates it, as testosterone does; RAD-140 is one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTissue selectivity\u003c\/strong\u003e: the design goal of a SARM, strong receptor activation in muscle and bone with weak activation in the prostate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCholestasis\u003c\/strong\u003e: reduced flow of bile from the liver, the pattern of injury described in several RAD-140 case reports.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTransaminases (AST and ALT)\u003c\/strong\u003e: enzymes released into the blood when liver cells are stressed or damaged.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetention time\u003c\/strong\u003e: the point at which a compound emerges from a chromatography column, compared with a reference standard in an identity test.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003em\/z\u003c\/strong\u003e: the mass-to-charge value a mass spectrometer assigns to an ion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent assay\u003c\/strong\u003e: measurement of how much compound a single unit, such as one capsule, holds, as distinct from its purity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBenzoate ester\u003c\/strong\u003e: a molecule joined to benzoic acid through an ester bond, which adds mass; RAD-150 is described as the benzoate ester of RAD-140.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-specified substance\u003c\/strong\u003e: a prohibited substance not regarded as likely to be taken for reasons other than performance; all S1 anabolic agents qualify.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMarketing authorisation\u003c\/strong\u003e: the MHRA licence a product needs before it can be sold as a medicine in the UK.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eAbout Thoroughbred Labs RAD-140\u003c\/h2\u003e\u003cp\u003eThoroughbred Labs sells through its own website, thoroughbredlabs.co.uk, with no shop premises; its statutory notice names 24\/7 Billing Limited (Companies House number 14990140, London, active, incorporated July 2023). Its range is split into peptide vials, encapsulated compounds and multi-product Research Systems, and RAD140 is one of the encapsulated compounds, sold in that form only. Nothing the brand publishes names where its capsules are made, and it publishes no stockist list, so we describe it from its site and its packaging alone.\u003c\/p\u003e\u003cp\u003eOn the front of the tub the code RAD140 sits above the secondary name TESTOLONE and the count 60 CAPSULES. The brand's own product page gives this one no strength in its title or text, which is why earlier versions of this listing recorded none; the FACTS panel on the side of the tub does state it, Amount per capsule RAD140 10mg, the other ingredients being organic rice flour and then magnesium stearate, in a vegetarian shell. That panel is the brand's claim. As checked on 2 October 2026, its certificate page listed no report of any kind for RAD140 capsules, so this listing shows none and we make no analytical statement about the batch in stock.\u003c\/p\u003e\u003cp\u003eOn stated facts the RAD-140 brands here match: 10 mg per capsule and 60 capsules for Thoroughbred Labs, \u003ca href=\"\/en-ro\/products\/imuscle-testolon-rad-140-60-10mg\"\u003eiMuscle\u003c\/a\u003e and \u003ca href=\"\/en-ro\/products\/yakka-strength-yakka-strength-rad140\"\u003eYakka Strength\u003c\/a\u003e, and for Free Muscle's own 10 mg pack, the one of the four with a Janoshik certificate for each batch. The differences lie in fillers and documents, set out in the \u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 collection\u003c\/a\u003e and the \u003ca href=\"\/en-ro\/collections\/brand-thoroughbred-labs\"\u003eThoroughbred Labs collection\u003c\/a\u003e. Before relying on a tub, check the shrink seal and note the batch number, then ask us what paperwork exists for it.\u003c\/p\u003e\u003cp\u003eRAD-140 itself is a non-steroidal androgen receptor ligand first reported in 2011 whose single human trial was in cancer patients; no regulator has licensed it, UK law treats it as neither medicine nor food, and WADA names it in S1.2 among other anabolic agents, banned at all times. It is supplied here to adults for laboratory research only.\u003c\/p\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eAll brands of RAD-140 (Testolone)\u003c\/a\u003e, compared on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/brand-thoroughbred-labs\"\u003eAll Thoroughbred Labs products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/rad-150\"\u003eRAD-150 (TLB-150)\u003c\/a\u003e and the wider \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eSARMs range\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e, covering the liver injury case reports\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eMiller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-9. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24900290\/\" rel=\"noopener\"\u003ePMID: 24900290\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34565686\/\" rel=\"noopener\"\u003ePMID: 34565686\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eVan Wagoner RM, et al. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004-2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29183075\/\" rel=\"noopener\"\u003ePMID: 29183075\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eWagener F, et al. Human In Vivo Metabolism and Elimination Behavior of Micro-Dosed Selective Androgen Receptor Modulator RAD140 for Doping Control Purposes. Metabolites. 2022;12(7):666. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35888790\/\" rel=\"noopener\"\u003ePMID: 35888790\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLeung K, et al. RAD-140 Drug-Induced Liver Injury. Ochsner J. 2022;22(4):361-365. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36561105\/\" rel=\"noopener\"\u003ePMID: 36561105\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eChong S, et al. Reversible Gynecomastia and Hypogonadism Due to Usage of Commercial Performance-Enhancing Supplement Use. JCEM Case Rep. 2024;2(8):luae148. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39145153\/\" rel=\"noopener\"\u003ePMID: 39145153\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Thoroughbred Labs","offers":[{"title":"Default Title","offer_id":48468980564194,"sku":null,"price":38.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/RAD_085f5beb-b376-4e42-84da-23b9650f2ac9.png?v=1789931429"},{"product_id":"yakka-strength-yakka-strength-rad140","title":"Yakka Strength RAD-140","description":"\u003cp\u003eYakka Strength RAD-140 is a 60-capsule pot of the selective androgen receptor modulator RAD-140, also known as testolone, distributed by Yakka Strength Ltd and stocked by Free Muscle as part of the Muscle Market range. The label facts panel states 10 mg of RAD140 per capsule, which is 600 mg per pot as labelled.\u003c\/p\u003e\u003ch2\u003eAbout RAD-140\u003c\/h2\u003e\u003cp\u003eRAD-140 is a non-steroidal selective androgen receptor modulator (SARM). It was designed by Radius Health as an orally active compound that binds the androgen receptor and, in preclinical work, showed a stronger effect on skeletal muscle than on the prostate. The 2011 characterisation paper described it as potent and orally bioavailable and reported its activity in several preclinical animal models of anabolic androgen action. Animal results do not show how it behaves in people.\u003c\/p\u003e\u003cp\u003eClinical data are limited to a single first-in-human Phase 1 study in 22 postmenopausal women with ER-positive, HER2-negative metastatic breast cancer, published in 2022. The investigators described the safety profile as acceptable, but raised liver enzymes (AST in 59.1 per cent of participants, ALT in 45.5 per cent) and raised bilirubin were the most frequent treatment-emergent adverse events, and 16 of the 22 had a grade 3 or 4 event. The same study measured an elimination half-life of 44.7 hours. Sex hormone-binding globulin fell in all 18 participants in whom it was measured and prostate-specific antigen rose in 16 of 20, markers that the androgen receptor was being engaged well beyond muscle.\u003c\/p\u003e\u003cp\u003eRAD-140 has never been approved as a medicine anywhere in the world. Nothing in these studies is a claim about this product.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIdentifier\u003c\/th\u003e\n\u003cth\u003eRAD-140\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOther names\u003c\/td\u003e\n\u003ctd\u003eTestolone, vosilasarm, EP0062\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAS number\u003c\/td\u003e\n\u003ctd\u003e1182367-47-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular formula\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e393.8 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInChIKey\u003c\/td\u003e\n\u003ctd\u003eXMBUPPIEVAFYHO-KPZWWZAWSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePubChem CID\u003c\/td\u003e\n\u003ctd\u003e44200882\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eIdentifiers are from PubChem. The formula and molecular weight are the values to check a mass-spectrometry result against.\u003c\/p\u003e\u003ch2\u003eThis listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCompound: RAD-140 (Testolone)\u003c\/li\u003e\n\u003cli\u003eBrand and distributor: Yakka Strength Ltd, named on the back panel; the side panel adds \"Made in the UK\"; manufacturer not named\u003c\/li\u003e\n\u003cli\u003eForm: capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStrength per capsule: 10 mg RAD140, as printed in the label facts panel\u003c\/li\u003e\n\u003cli\u003eTotal per pot: 60 x 10 mg, 600 mg as labelled\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption\u003c\/li\u003e\n\u003cli\u003eSold to adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWith 600 mg per pot printed on the label, this pot can be set against other RAD-140 brands on cost per milligram; the method is in \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003ehow to compare by milligram\u003c\/a\u003e. A labelled figure is a declaration; a measured content, where a batch certificate gives one, is covered below.\u003c\/p\u003e\u003ch2\u003eRAD-140 in the UK: buying, legal status and what to check\u003c\/h2\u003e\u003cp\u003eSearches such as \"RAD 140 UK\" and \"RAD140 for sale UK\" ask two things: is buying it lawful, and how is a sound listing told apart from a poor one.\u003c\/p\u003e\u003ch3\u003eThe legal position\u003c\/h3\u003e\u003cp\u003eRAD-140 is not a controlled drug in the UK. It sits outside both routes by which a substance can be sold for people: the MHRA has never granted it a marketing authorisation, so it cannot be sold as a medicine, and it is not an authorised food supplement, so it cannot be sold as food. What remains is sale as a research compound for laboratory work, the only basis on which Free Muscle lists it, and only to buyers aged 18 or over. WADA bans it at all times, so a tested athlete stands in a different position from a laboratory buyer. Buyers are responsible for the rules that apply to them. Background on the class is in \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e.\u003c\/p\u003e\u003ch3\u003eWhy the listing matters\u003c\/h3\u003e\u003cp\u003eResearchers at LGC in Fordham, Cambridgeshire, bought a range of products sold to UK consumers as SARMs and analysed them by high-resolution mass spectrometry. One contained no active ingredient, others contained prohibited substances not declared on the label, and where a SARM was present the measured amount differed from the packaging. The paper also notes that neither the European Medicines Agency nor the US Food and Drug Administration has approved any SARM. Because a label alone guarantees nothing, a trustworthy UK listing shows:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eA batch or lot number\u003c\/strong\u003e on the pack that can be matched to a certificate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for that batch\u003c\/strong\u003e, with identity, purity and a test date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA stated strength per capsule\u003c\/strong\u003e, so the total per pack can be worked out and checked.\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eA named manufacturer and a traceable UK seller.\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-use terms\u003c\/strong\u003e: an 18+ restriction and no usage instructions or outcome claims.\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eTracked delivery in plain packaging.\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eHow this listing measures up\u003c\/h3\u003e\u003cp\u003eOn most points. The distributor is named on the label, and the seller is FreeMuscle, a business registered in Andorra with UK operations and dispatch in Scunthorpe. Every order goes by free tracked UK delivery in plain packaging, orders placed before 2pm Monday to Friday are processed the same working day, EU delivery takes 3-7 working days, and unopened items can be returned within 30 days. The label states 10 mg per capsule, so the strength point is met; the open point is the certificate, because only a batch certificate supplied by the brand can confirm a measured content. Forum and Reddit threads found by searches like \"RAD 140 UK review\" cannot show what a given pack contained. More checks are in \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\u003cp\u003eRAD-140 is sold as capsules, pressed tablets and \"research liquids\", hence searches for \"RAD 140 tablets\" and \"RAD 140 liquid UK\". The molecule is the same in each; what differs is how well each format holds it and how precisely each unit is measured.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsules.\u003c\/strong\u003e A weighed or volume-filled quantity of powder, usually blended with a filler, is sealed in a shell. The amount per unit is fixed at manufacture, so its accuracy depends on how evenly the blend was mixed and filled. A dry powder in a closed shell is the least exposed of the three formats to moisture and oxygen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTablets.\u003c\/strong\u003e Powder is compressed with binders. The content per unit is also fixed at manufacture and depends on the same blending step, with compression adding further excipients.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquids.\u003c\/strong\u003e The content per millilitre depends on the compound dissolving completely and staying in solution, and every measured volume is only as accurate as the dropper or pipette used. Compounds in solution are generally more open to degradation than dry solids, and concentration drifts if solvent evaporates.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eRAD-140 is a small molecule of about 394 daltons, not a peptide, so the digestion problem that limits peptides given by mouth does not apply to it (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e). Its discoverers described it as orally bioavailable in animal models, and the published human data concern oral administration only. None of this says that any form produces an effect. For laboratory purposes the practical difference is verification: a capsule certificate can report content per unit, a liquid certificate reports concentration, and either has to match its own batch.\u003c\/p\u003e\u003ch2\u003eRAD-140 compared with RAD-150\u003c\/h2\u003e\u003cp\u003e\"RAD 140 vs RAD 150\" is the comparison most often searched for this compound. RAD-150, also sold as TLB-150, is not a separate drug programme. PubChem records it as TLB 150 benzoate (CID 68547459): RAD-140 with a benzoate group joined as an ester to its hydroxyl group. It appears as a numbered compound in US patent 8,629,167, but a PubMed search under RAD-150, TLB-150 and related names returns no study of it.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003ePoint\u003c\/th\u003e\n\u003cth\u003eRAD-140\u003c\/th\u003e\n\u003cth\u003eRAD-150 (TLB-150)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eChemical type\u003c\/td\u003e\n\u003ctd\u003eNon-steroidal SARM\u003c\/td\u003e\n\u003ctd\u003eBenzoate ester of RAD-140\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula\u003c\/td\u003e\n\u003ctd\u003eC20H16ClN5O2\u003c\/td\u003e\n\u003ctd\u003eC27H20ClN5O3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular weight\u003c\/td\u003e\n\u003ctd\u003e393.8\u003c\/td\u003e\n\u003ctd\u003e497.9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eComputed XLogP3\u003c\/td\u003e\n\u003ctd\u003e3.1\u003c\/td\u003e\n\u003ctd\u003e5.4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAnimal studies\u003c\/td\u003e\n\u003ctd\u003ePreclinical animal data, 2011\u003c\/td\u003e\n\u003ctd\u003eNone published\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman studies\u003c\/td\u003e\n\u003ctd\u003eOne Phase 1 trial (22 women); anti-doping excretion studies\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK status\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research compound\u003c\/td\u003e\n\u003ctd\u003eUnlicensed; research compound\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eNamed in S1.2\u003c\/td\u003e\n\u003ctd\u003eNot named; within S1.2 wording\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThree things follow from the structure. The RAD-140 portion makes up about 79 per cent of the ester by mass, so label milligrams of the two are not interchangeable figures. The ester is markedly more fat-soluble on computed values. And an ester bond can be split by water, which makes humidity and heat more relevant to its storage. Claims that RAD-150 is longer-acting or stronger have never been measured, and whether it is converted to RAD-140 in a living system has not been reported.\u003c\/p\u003e\u003cp\u003eIn sport, RAD-140 is named in section S1.2 of the WADA Prohibited List; RAD-150 is not, but S1.2 opens with the words \"including, but not limited to\", so an unnamed SARM derivative is not outside it. Brands held are in the \u003ca href=\"\/en-ro\/collections\/rad-150\"\u003eRAD-150 (TLB-150) collection\u003c\/a\u003e, and the chemistry is set out at length in \u003ca href=\"\/en-ro\/blogs\/news\/rad-140-vs-rad-150-tlb-150\"\u003eRAD-140 vs RAD-150 (TLB-150)\u003c\/a\u003e.\u003c\/p\u003e\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\u003cp\u003eAny certificate of analysis (COA) for this product would come through Yakka Strength, which the label names as distributor; it names no manufacturer or laboratory. Our rule for their stock: a COA appears only when the brand has supplied one for the batch we hold. If one exists for the current batch it is linked here or sent by email on request; if not, we say so rather than substitute a generic PDF. Free Muscle-brand batches, such as \u003ca href=\"\/en-ro\/products\/free-muscle-rad-140-testolone-10mg\"\u003eFree Muscle RAD-140 Testolone 10mg\u003c\/a\u003e, are independently assayed at Janoshik Analytical; that does not extend to Yakka Strength. Where a Yakka Strength certificate exists, read these fields.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity.\u003c\/strong\u003e Confirms the sample is RAD-140. By HPLC, identity rests on the main peak matching the retention time of a reference standard. LC-MS is stronger: RAD-140 gives a protonated molecule at m\/z 394, the ion anti-doping chemists track in urine, while an ion near m\/z 498, calculated for RAD-150, would point to the ester.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity.\u003c\/strong\u003e Usually an HPLC area percentage, the share of detected material that is RAD-140. It describes the compound, not the capsule, and says nothing about how much RAD-140 each capsule holds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule.\u003c\/strong\u003e The key line for this product: a measured milligram figure per capsule to set against the 10 mg the label declares.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number.\u003c\/strong\u003e Must match the lot printed on the pack.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest date and laboratory.\u003c\/strong\u003e The date shows how old the result is; the laboratory name allows the report to be checked with its issuer.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eFor this brand, a missing field has a specific meaning. No identity result leaves the compound unconfirmed; purity without content leaves the strength unknown; no batch number means the document does not verify the pack in hand. If a field is missing, \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e and we will say what exists for the current stock. Method is covered in \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ereading a COA\u003c\/a\u003e and on our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests\u003c\/a\u003e page.\u003c\/p\u003e\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\u003cp\u003eRAD-140 is prohibited at all times, in and out of competition, under section S1.2 (other anabolic agents) of the WADA Prohibited List, where it is named as an example of a SARM. Anti-doping rules apply strict liability: an athlete is responsible for any prohibited substance found in their sample, whatever its source.\u003c\/p\u003e\u003cp\u003eThe most detailed human elimination data come from a 2022 study at the German Sport University Cologne. In six controlled excretion studies, each with five adult male volunteers given very small amounts of RAD-140, urine was analysed by LC-HRMS\/MS. Concentrations peaked two to six hours after administration and then fell slowly. Unchanged RAD-140 remained detectable for up to 29 days after a single administration of the largest amount studied, and it accumulated when administration was repeated on consecutive days. The parent compound was detectable for longest, and several metabolites were described in human urine for the first time. The authors framed the work partly around contaminated supplements, which can also cause positive findings.\u003c\/p\u003e\u003cp\u003eNo published study gives a detection window for the quantities in commercial capsules, so for this product the accurate statement is: detectable, window not established. For anyone in a tested sport, any exposure carries the risk of a positive test.\u003c\/p\u003e\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\u003cp\u003eKeep the pack sealed in its original container, closed between openings, in a cool, dry cupboard away from direct light and heat. Moisture is the main risk to capsules: capsule shells, gelatine ones in particular, soften and stick together in humid air and turn brittle when very dry, and damp powder degrades faster than dry. Heat speeds up both. Do not decant capsules into unlabelled containers: the batch number on the original pack is what ties the contents to a certificate.\u003c\/p\u003e\u003cp\u003eWe are not aware of published stability data for RAD-140 in capsule form, so the expiry or best-before date on the pack, where printed, is the limit to work within. Note the date the pack was first opened next to the batch number. Ordinary laboratory good practice applies: wear gloves when handling opened capsules or powder, work away from food and drink, keep the pack out of reach of children and animals, label any sample taken from the pack with compound, batch and date, and dispose of unwanted material as chemical waste, not via household bins or drains.\u003c\/p\u003e\u003ch2\u003eGlossary\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSARM\u003c\/strong\u003e: selective androgen receptor modulator, a non-steroidal androgen receptor ligand designed to act more on muscle and bone than on the prostate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAndrogen receptor\u003c\/strong\u003e: the nuclear receptor activated by testosterone and dihydrotestosterone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTestolone and vosilasarm\u003c\/strong\u003e: other names for RAD-140; testolone is an informal market name, vosilasarm the non-proprietary name used in reference databases such as PubChem.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEster\u003c\/strong\u003e: a compound formed by joining an acid to an alcohol group; RAD-150 is the benzoic acid ester of RAD-140.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHalf-life\u003c\/strong\u003e: the time taken for the concentration of a compound in the blood to fall by half.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhase 1 trial\u003c\/strong\u003e: the first stage of human testing, focused on tolerability and pharmacokinetics in a small group.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC\u003c\/strong\u003e: high-performance liquid chromatography, which separates a sample into its components; the usual basis of a purity figure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLC-MS\u003c\/strong\u003e: liquid chromatography with mass spectrometry, which also measures molecular mass and so gives firmer proof of identity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCertificate of analysis (COA)\u003c\/strong\u003e: a laboratory report on one specific batch, carrying its batch number and test date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWADA S1.2\u003c\/strong\u003e: the Prohibited List section for other anabolic agents, including SARMs, banned at all times.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMHRA\u003c\/strong\u003e: the Medicines and Healthcare products Regulatory Agency.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eAbout Yakka Strength RAD-140\u003c\/h2\u003e\n\u003cp\u003eYakka Strength sells this pot as \"RAD140 Testolone\": that is the front label, in red lettering on the brand's standard black design, above \"60 capsules\" and the research-purposes-only line; the side panel carries a short facts table, RAD140 10 mg per capsule and 60 capsules per container, which makes 600 mg per pot as labelled, plus \"Made in the UK\", and the back panel gives Yakka Strength Ltd as distributor. The company is registered at Companies House (13284431) in County Durham and says two brothers started it as a gym equipment business; its capsule range is a sideline of eleven products. No manufacturer or testing laboratory is named on the pot or on the brand's website.\u003c\/p\u003e\n\u003cp\u003eWithin that range RAD140 appears three times: as this pot, as one half of the \u003ca href=\"\/en-ro\/products\/yakka-strength-yakka-strength-mk677-rad140\"\u003eMK-677 + RAD-140 pot\u003c\/a\u003e, where each capsule holds 10 mg of each compound, and inside the \u003ca href=\"\/en-ro\/products\/yakka-strength-yakka-strength-rad140-enclomiphene-bundle\"\u003eRAD-140 and Enclomiphene bundle\u003c\/a\u003e, which is this pot packed with the brand's enclomiphene citrate pot. The \u003ca href=\"\/en-ro\/collections\/brand-yakka-strength\"\u003eYakka Strength brand page\u003c\/a\u003e lists all eleven. Because the brand's site publishes no certificates, a pot can only be checked through us: find the lot number on the container (the printed label has no batch field), then ask what document, if any, Yakka Strength has supplied for that batch, and read its identity and content lines against the 10 mg on the label.\u003c\/p\u003e\n\u003cp\u003eRadius Health developed RAD-140 as a non-steroidal SARM. Its only published clinical trial was a small early-phase study in breast cancer patients; no regulator has ever approved it as a medicine, it cannot lawfully be sold as a food supplement in the UK, and it sits in WADA's section S1.2 as an anabolic agent prohibited at all times. On stated figures, \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle\u003c\/a\u003e also labels its RAD-140 at 10 mg in 60 capsules, \u003ca href=\"\/en-ro\/collections\/brand-thoroughbred-labs\"\u003eThoroughbred Labs\u003c\/a\u003e prints 10 mg in 60 on its label facts panel (its product text gives no figure), and Free Muscle's RAD-140 is 10 mg in 60, each batch going to Janoshik Analytical for assay. The \u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 collection\u003c\/a\u003e compares them; no brand is ranked above another.\u003c\/p\u003e\n\u003ch2\u003eRelated\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/rad-140\"\u003eRAD-140 (Testolone) collection\u003c\/a\u003e: every brand we stock, side by side on strength, pack size and batch testing\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/brand-yakka-strength\"\u003eAll Yakka Strength products\u003c\/a\u003e stocked at Free Muscle\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/sarms\"\u003eSARMs\u003c\/a\u003e, the wider range\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/blogs\/news\/rad-140-testolone-what-the-research-says\"\u003eRAD-140 (testolone): what the research says\u003c\/a\u003e, including the reported side effects\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eReferences\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eMiller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-9. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24900290\/\" rel=\"noopener\"\u003ePMID: 24900290\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLoRusso P, et al. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+\/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022;22(1):67-77. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34565686\/\" rel=\"noopener\"\u003ePMID: 34565686\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eLeaney AE, et al. Analysis of supplements available to UK consumers purporting to contain selective androgen receptor modulators. Drug Test Anal. 2021;13(1):122-127. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32748554\/\" rel=\"noopener\"\u003ePMID: 32748554\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eWagener F, et al. Human In Vivo Metabolism and Elimination Behavior of Micro-Dosed Selective Androgen Receptor Modulator RAD140 for Doping Control Purposes. Metabolites. 2022;12(7):666. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35888790\/\" rel=\"noopener\"\u003ePMID: 35888790\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eBasaria S, et al. The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci. 2013;68(1):87-95. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22459616\/\" rel=\"noopener\"\u003ePMID: 22459616\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Yakka Strength","offers":[{"title":"Default Title","offer_id":48468982792418,"sku":null,"price":55.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/yakka-strength-rad140-pack-shot-white.jpg?v=1791052912"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/collections\/openart-image_5GqoU6sK_1760820649070_raw_2e570237-2351-490e-a6a5-64bdfb2fd16d.jpg?v=1790530356","url":"https:\/\/freemuscle.co.uk\/en-ro\/collections\/sarms.oembed","provider":"Free Muscle","version":"1.0","type":"link"}