{"title":"SR9009 (Stenabolic)","description":"\u003cp\u003eSR9009, sold under the name Stenabolic and sometimes written SR-9009, is a synthetic small-molecule agonist of the nuclear receptors Rev-Erbα and Rev-Erbβ, which sit at the heart of the circadian clock and regulate genes for lipid and glucose metabolism. It is not a SARM, has never been studied in a human trial and is not an approved medicine anywhere. This page lists every brand of SR9009 stocked at Free Muscle, compared on strength per capsule, capsules per pack and batch testing.\u003c\/p\u003e\n\u003ch2\u003eWhat is SR9009?\u003c\/h2\u003e\n\u003cp\u003eSR9009 was designed at the Scripps Research Institute in Florida as a research tool for studying Rev-Erb, together with a sister compound, SR9011. Rev-Erb proteins are transcriptional repressors: when activated they switch off target genes, including core clock genes and genes involved in fat storage, gluconeogenesis and inflammation. In mice, activating Rev-Erb altered circadian behaviour and raised energy expenditure, which is the origin of the reputation the compound later acquired in the fitness market.\u003c\/p\u003e\n\u003cp\u003eTwo facts limit that reputation. First, the animal studies gave SR9009 by injection, and we found no study, searching PubMed in October 2026, that measured how much SR9009 reaches the blood when it is taken by mouth, so whether a capsule delivers meaningful amounts is unknown. Second, a 2019 study using mice with both Rev-Erb genes deleted found that SR9009 still changed cell viability and metabolism, so some of its effects are not mediated by Rev-Erb at all and its true mechanism is unresolved. There are no human trials, no human safety studies and no regulatory approval. The 2026 WADA Prohibited List names SR9009, with SR9011, as a Rev-Erbα agonist in section S4.4 (metabolic modulators), prohibited at all times.\u003c\/p\u003e\n\u003cp\u003eIdentifiers (PubChem CID 57394020, checked October 2026): CAS 1379686-30-2, formula C20H24ClN3O4S, molar mass 437.9 g\/mol.\u003c\/p\u003e\n\u003ch2\u003eWhat the published research reports\u003c\/h2\u003e\n\u003cp\u003eThe 2012 Nature paper that introduced SR9009 reported that injected SR9009 altered circadian gene expression in mice, increased energy expenditure and reduced fat mass and plasma lipids in diet-induced obese mice, without changing food intake (Solt 2012). A 2013 study in Nature Medicine reported that Rev-Erbα regulates mitochondrial content in skeletal muscle and that injected SR9009 increased running endurance in mice, alongside greater mitochondrial biogenesis (Woldt 2013). A 2016 in vitro study of SR9009 and SR9011 metabolism, carried out for anti-doping purposes, characterised the metabolites produced by liver enzymes so that laboratories could detect the compound in athletes (Geldof 2016). Then in 2019 a group at the University of Pennsylvania showed that SR9009 decreased cell viability and rewired metabolism in hepatocytes and embryonic stem cells that lacked both Rev-Erbα and Rev-Erbβ, concluding that its effects cannot be used as a proxy for Rev-Erb activity (Dierickx 2019).\u003c\/p\u003e\n\u003cp\u003eOther findings are limiting. In mice, SR9009 changed sleep architecture, increasing wakefulness during the light period when mice normally rest (Amador 2016). Every efficacy result is from injected mice or cultured cells.\u003c\/p\u003e\n\u003cp\u003eIn people, two case reports describe liver injury after use: in 2025, hepatocellular injury in a 40-year-old man taking several supplements who had recently started a product sold as Stenabolic, and who improved after stopping it (Govil 2025); and in 2026, acute liver failure needing an emergency liver transplant in a 17-year-old, with viral, autoimmune, metabolic and obstructive causes excluded (Shams Bin Shaheen 2026). Case reports show an association in time, not proof of cause. None of the above is a claim about any product on this page.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSolt LA, et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature. 2012;485(7396):62-68. PMID: 22460951.\u003c\/li\u003e\n\u003cli\u003eWoldt E, et al. Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy. Nat Med. 2013;19(8):1039-1046. PMID: 23852339.\u003c\/li\u003e\n\u003cli\u003eGeldof L, et al. In Vitro Metabolic Studies of REV-ERB Agonists SR9009 and SR9011. Int J Mol Sci. 2016;17(10):1676. PMID: 27706103.\u003c\/li\u003e\n\u003cli\u003eDierickx P, et al. SR9009 has REV-ERB-independent effects on cell proliferation and metabolism. Proc Natl Acad Sci U S A. 2019;116(25):12147-12152. PMID: 31127047.\u003c\/li\u003e\n\u003cli\u003eAmador A, et al. Pharmacological Targeting the REV-ERBs in Sleep\/Wake Regulation. PLoS One. 2016;11(9):e0162452. PMID: 27603791.\u003c\/li\u003e\n\u003cli\u003eVan Wagoner RM, et al. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004-2010. PMID: 29183075.\u003c\/li\u003e\n\u003cli\u003eGovil D, et al. When Gains Go Wrong: A Case of Selective Androgen Receptor Modulator-Related Liver Injury. Cureus. 2025;17(7):e87376. PMID: 40765588.\u003c\/li\u003e\n\u003cli\u003eShams Bin Shaheen S, et al. Acute Liver Failure in an Adolescent Following Use of the Synthetic REV-ERB Agonist SR9009. Case Reports Hepatol. 2026;2026:9926772. PMID: 42750938.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eBrands of SR9009 we stock\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/products\/imuscle-stenabolic-sr-9009-60-10mg\"\u003eiMuscle Stenabolic SR-9009, 10mg, 60 capsules\u003c\/a\u003e. iMuscle brand, capsule form, 10mg per capsule, 60 capsules, 600mg in the pack. The listing currently shows two iMuscle documents, both dated 2021: a test protocol giving an HPLC assay of 99.9 per cent and an HPLC report for lot 20210911 with a main peak of 99.0 per cent. Compare that lot number with the one on your pack; if they differ, the documents do not describe your batch. We show only what iMuscle supplies and do not imply a test that does not exist.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThere is currently no Free Muscle-brand SR9009, so no listing on this page carries a Janoshik Analytical certificate. As further brands are added they will appear here with the same information: strength, count, form and batch documentation.\u003c\/p\u003e\n\u003ch3\u003eHow to compare them\u003c\/h3\u003e\n\u003cp\u003eStrength per capsule multiplied by capsules per pack gives total compound: 60 capsules at 10mg is 600mg. Divide the price by that figure for cost per milligram. When a second brand is listed, compare on that number and on whether a batch-specific certificate exists, not on the label design or the name on the tub. The Stenabolic name is a marketing term and tells you nothing about what is in the capsule.\u003c\/p\u003e\n\u003ch2\u003eBatch testing and certificates of analysis\u003c\/h2\u003e\n\u003cp\u003eFor SR9009, a certificate of analysis should show, by HPLC or LC-MS against an SR9009 reference standard, that the material is SR9009, and give the purity, the laboratory, the batch number and the test date. Identity matters here. An analysis of 44 products bought online as SARMs found another unapproved drug, SR9009 among them, in 39 per cent, unlisted substances in a quarter and the labelled amount in only 41 per cent (Van Wagoner 2017), and a doping-control laboratory found SR9009 in a black-market product (Geldof 2016).\u003c\/p\u003e\n\u003cp\u003eFor iMuscle, the only brand on this page, we show a certificate only when the manufacturer provides one for the batch in stock. Whatever its source, a PDF without a batch number, test date or named laboratory is not a batch certificate, and its batch number should match your pack. Our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests page\u003c\/a\u003e explains what to look for.\u003c\/p\u003e\n\u003ch2\u003eWhere to buy SR9009 in the UK: how to check a supplier\u003c\/h2\u003e\n\u003cp\u003eWhichever shop you buy SR9009 from, check these five points before you order:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eA batch number and a certificate for that batch.\u003c\/strong\u003e The pack should carry a batch number, and the seller should be able to show a certificate of analysis for that same batch from a named laboratory, with the test date. For iMuscle, a certificate is shown where the brand supplies one for the batch we hold.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe strength per capsule and the capsule count.\u003c\/strong\u003e With both figures you can work out the total milligrams in the pack and the price per milligram. If a listing does not state one of them, ask the seller before you order.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-use labelling and an age check.\u003c\/strong\u003e A research compound should be sold for laboratory research use only, not for human consumption, to adults aged 18 or over, with no dosing or usage advice. That is how every listing here is sold.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrices in pounds sterling and tracked UK dispatch.\u003c\/strong\u003e UK delivery from us is free and tracked on every order, with no minimum spend, and usually arrives 2-3 working days after dispatch; orders placed before 2pm Monday to Friday are processed the same working day.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA clear returns policy.\u003c\/strong\u003e Unopened items can be returned to us within 30 days.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eBrand on this page: \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle\u003c\/a\u003e. The \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003ehow we test\u003c\/a\u003e go into more detail.\u003c\/p\u003e\n\n\u003ch2\u003eLegal status in the UK\u003c\/h2\u003e\n\u003cp\u003eSR9009 holds no MHRA marketing authorisation, which means it is not licensed as a medicine in the UK. Nor does it hold any food supplement authorisation, so it may not be sold for people to consume. The Misuse of Drugs Act 1971 does not list it, and Free Muscle supplies it for laboratory research to adults only. In sport, the 2026 WADA Prohibited List names it in section S4.4, metabolic modulators, as a Rev-Erbα agonist, banned at all times. Our \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eSARMs research guide\u003c\/a\u003e explains how UK law treats research compounds.\u003c\/p\u003e\n\u003ch2\u003eStorage and handling\u003c\/h2\u003e\n\u003cp\u003eStore the sealed container somewhere cool, dry and dark, close it promptly after each opening, and keep the capsules in their labelled container with the batch number, out of reach of children and animals. Wear gloves and work on a clean surface when handling them, and send unwanted material to a chemical waste route rather than the sink.\u003c\/p\u003e\n\u003ch2\u003eDelivery and returns\u003c\/h2\u003e\n\u003cp\u003eFree Muscle is the trading name of FreeMuscle, a business registered in Andorra, with UK operations and dispatch in Scunthorpe. Orders to UK addresses go by free tracked delivery in plain packaging, an order placed before 2pm from Monday to Friday is processed that working day, and parcels for the EU take three to seven working days. Unopened items may be sent back within 30 days, and nobody under 18 may order. See the \u003ca href=\"\/en-ro\/pages\/shipping\"\u003eshipping page\u003c\/a\u003e and the \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee page\u003c\/a\u003e for full terms.\u003c\/p\u003e\n\u003ch2\u003eRelated reading\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 (Stenabolic): what the REV-ERB research shows\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003eCardarine (GW-501516): why development stopped and what the data show\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eWhat are SARMs? The 2026 research guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003ePrice per milligram: the only honest way to compare\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003eHow to read a certificate of analysis\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eCardarine (GW-501516)\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/slu-pp-332\"\u003eSLU-PP-332\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/weight-loss\"\u003emetabolic support\u003c\/a\u003e and \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eall SARMs\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"imuscle-stenabolic-sr-9009-60-10mg","title":"iMuscle Stenabolic SR-9009 — 60 caps, 10mg","description":"\u003cp\u003e\u003cstrong\u003eiMuscle Stenabolic SR-9009, 60 caps, 10mg\u003c\/strong\u003e is an iMuscle listing of SR9009, labelled at 10 mg per capsule, 60 capsules per pack. It is supplied through the \u003ca href=\"\/en-ro\/pages\/muscle-market\"\u003eMuscle Market\u003c\/a\u003e range for laboratory research only, is not for human consumption, and is sold to adults aged 18 and over. Below: what the published research on SR9009 reports, what the label documents, where the compound stands in UK law and in sport, how to read a batch certificate for it, and how batch certificates are handled for iMuscle products.\u003c\/p\u003e\n\u003ch2\u003eAbout SR9009\u003c\/h2\u003e\n\u003cp\u003eSR9009, sold under the name Stenabolic, is a synthetic agonist of REV-ERB alpha and REV-ERB beta, nuclear receptors that connect the circadian clock to the expression of metabolic genes. It was developed at the Scripps Research Institute by Burris and colleagues. It is not a SARM and has no described activity at the androgen receptor.\u003c\/p\u003e\n\u003cp\u003ePubChem records it as CID 57394020, CAS number 1379686-30-2, molecular formula C20H24ClN3O4S and molecular weight 437.9, with InChIKey MMJJNHOIVCGAAP-UHFFFAOYSA-N. Its systematic name is ethyl 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate. These identifiers are what any certificate of analysis should be checked against.\u003c\/p\u003e\n\u003ch2\u003eWhat the published research reports\u003c\/h2\u003e\n\u003cp\u003eIn a 2012 study published in Nature, mice given SR9009 by injection showed altered circadian behaviour, and the circadian pattern of metabolic gene expression in liver, muscle and fat changed, with increased energy expenditure. Diet-induced obese mice treated with the agonist lost fat mass and showed improved dyslipidaemia and hyperglycaemia (Solt et al., 2012). A 2013 mouse study led from the Institut Pasteur de Lille, with the Scripps group as co-authors, linked REV-ERB alpha to mitochondrial number in skeletal muscle and reported that pharmacological activation of the receptor increased exercise capacity in mice (Woldt et al., 2013). In 2019 a group at the University of Pennsylvania reported that SR9009 changed cell proliferation and metabolism in cells lacking REV-ERB altogether, showing that some of its effects are off-target (Dierickx et al., 2019).\u003c\/p\u003e\n\u003cp\u003eThe animal studies used injection, and there are no published human trials or human pharmacokinetic data, so the behaviour of an oral capsule is unknown. It has never been approved as a medicine. Two further papers matter for anyone assessing SR9009 bought online. A Ghent University doping control laboratory confirmed SR9009 in a black market product bought over the internet and described eight metabolites formed by human liver enzymes in the test tube (Geldof et al., 2016). A 2017 analysis of 44 products sold online as SARMs found that 17 contained another unapproved drug, SR9009 among them, and that in only 18 of the 44 (41%) did the amount of active compound match the label (Van Wagoner et al., 2017). Nothing above is a claim about this product.\u003c\/p\u003e\n\u003ch2\u003eThis listing\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eManufacturer: iMuscle\u003c\/li\u003e\n\u003cli\u003eCompound: SR9009 (Stenabolic)\u003c\/li\u003e\n\u003cli\u003eForm: Capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStrength: 10 mg per capsule, as stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eTotal in pack: 600 mg (10 mg x 60 capsules)\u003c\/li\u003e\n\u003cli\u003eBatch certificate of analysis: shown where iMuscle supplies one for the batch we hold\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe 600 mg total is a label figure, calculated from the manufacturer's stated strength and capsule count. It becomes a measured figure only when a batch certificate reports content per capsule. Our guide to \u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e shows how to compare it with other SR9009 listings.\u003c\/p\u003e\n\u003ch2\u003eSR9009 in the UK: buying, legal status and what to check\u003c\/h2\u003e\n\u003cp\u003eThe searches \"SR9009 UK\", \"stenabolic UK\" and \"SR9009 UK sarms\" hide two questions: may it lawfully be sold here, and how do you tell a sound listing from a poor one. SR9009 is not a licensed medicine in the UK, has not been assessed by the MHRA, and is not an authorised food supplement. It is not a controlled drug. It is sold for laboratory research to adults aged 18 and over and is not for human consumption. Any seller offering instructions for taking it is marketing it outside that research basis.\u003c\/p\u003e\n\u003cp\u003eIn sport the position is stricter. SR9009 is named on the WADA Prohibited List under section S4 (hormone and metabolic modulators) alongside GW1516 and is prohibited at all times. Anyone subject to anti-doping rules should consult the current list. Our \u003ca href=\"\/en-ro\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eresearch guide\u003c\/a\u003e covers the wider legal picture for compounds sold next to SARMs.\u003c\/p\u003e\n\u003cp\u003eThe 2017 finding that SR9009 turned up in products labelled as something else is the best reason to judge an SR9009 listing on documents rather than on ratings or forum posts. The points worth checking, and how this listing answers each:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eNamed manufacturer and compound identifiers.\u003c\/strong\u003e This listing: iMuscle, with CAS 1379686-30-2 and the molecular formula given above, so a certificate can be matched to SR9009 and not to its sister compound SR9011.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrength and count on the label.\u003c\/strong\u003e iMuscle states 10 mg in each of 60 capsules.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate tied to the stock on sale.\u003c\/strong\u003e This listing: shown only where iMuscle supplies one for the batch we hold, and we say plainly when there is none.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWho is selling, and to whom.\u003c\/strong\u003e Here the seller is FreeMuscle, registered in Andorra, with UK operations and dispatch in Scunthorpe; buyers must be 18 or over, and unopened items may be returned within 30 days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow it travels.\u003c\/strong\u003e Every UK order goes out free with tracking, in plain packaging. Anything ordered by 2pm on a weekday is processed that day, and parcels to the EU take 3-7 working days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo usage guidance.\u003c\/strong\u003e This listing gives none, and neither does anything else on this site.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eDelivery and returns terms are set out on our \u003ca href=\"\/en-ro\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e pages. The \u003ca href=\"\/en-ro\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003eUK supplier checklist\u003c\/a\u003e applies the same tests to any shop, including this one.\u003c\/p\u003e\n\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\n\u003cp\u003eSR9009 is offered in three formats across the market: filled capsules like these, liquids in which the compound is dissolved or suspended, and loose powder. None of them has been studied for SR9009 in people. The published mouse studies used injected solutions prepared in the laboratory, so no commercial format, capsule or liquid, reproduces the conditions of that research. What differs is how each fixes the amount per unit.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsule fill.\u003c\/strong\u003e The stated 10 mg is blended with an inert filler and dosed into each shell by weight. Variation comes from blend uniformity and fill weight, and a laboratory can open and assay individual capsules to check both.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquid.\u003c\/strong\u003e The label states a concentration, often in a carrier that is not identified. The figure holds only while the compound stays evenly dissolved or suspended, and any volume drawn off depends on how accurately it is measured.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePowder.\u003c\/strong\u003e Accuracy moves entirely to the researcher's balance and technique, and a certificate describes the bulk material only.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe search \"SR9009 peptide\" reflects a common confusion. SR9009 is not a peptide: it has no amino acid chain for digestive enzymes to cut, which is the main obstacle for peptides given by mouth (see \u003ca href=\"\/en-ro\/blogs\/news\/do-oral-peptides-work\"\u003eDo oral peptides work?\u003c\/a\u003e). That does not mean oral SR9009 is well absorbed. With no human pharmacokinetic study published, the fraction of an oral amount reaching the circulation in people is simply unknown, and we do not suggest otherwise. For this pack, the useful property of the capsule format is that it gives a countable unit that a laboratory can test.\u003c\/p\u003e\n\u003ch2\u003eSR9009 compared with Cardarine\u003c\/h2\u003e\n\u003cp\u003e\"Stenabolic vs cardarine\" is a frequent search, because the two are sold next to each other and both appear in section S4 of the WADA list. The overlap largely ends there. The table sets out where they differ.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eQuestion\u003c\/th\u003e\n\u003cth\u003eSR9009 (Stenabolic)\u003c\/th\u003e\n\u003cth\u003eCardarine (GW-501516)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eReceptor it was designed for\u003c\/td\u003e\n\u003ctd\u003eREV-ERB alpha and beta, circadian clock receptors\u003c\/td\u003e\n\u003ctd\u003ePPAR-delta, a fatty acid metabolism receptor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWho made it and why\u003c\/td\u003e\n\u003ctd\u003eAn academic research tool for probing the clock\u003c\/td\u003e\n\u003ctd\u003eA pharmaceutical candidate for blood lipid disorders\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHighest level of evidence\u003c\/td\u003e\n\u003ctd\u003eMouse and cell studies only\u003c\/td\u003e\n\u003ctd\u003eShort human lipid trials\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKnown specificity problem\u003c\/td\u003e\n\u003ctd\u003eEffects in cells with no REV-ERB (2019)\u003c\/td\u003e\n\u003ctd\u003eDevelopment halted over rodent tumour findings\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOral data in people\u003c\/td\u003e\n\u003ctd\u003eNone published\u003c\/td\u003e\n\u003ctd\u003eGiven by mouth in human trials\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUK position\u003c\/td\u003e\n\u003ctd\u003eUnlicensed, research use only, 18+\u003c\/td\u003e\n\u003ctd\u003eUnlicensed, research use only, 18+\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSport\u003c\/td\u003e\n\u003ctd\u003eWADA S4, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eWADA S4, prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003ePut in plain terms, Cardarine is a failed drug candidate with some human data and a serious toxicology history, while SR9009 is a laboratory probe that was never taken into people at all. Neither is a SARM. The 2019 off-target finding also means that effects attributed to REV-ERB in SR9009 studies may partly come from other targets. We make no claim about either compound used together with any other. The \u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eCardarine collection\u003c\/a\u003e lists the brands we hold, and our article on \u003ca href=\"\/en-ro\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003ewhy Cardarine development stopped\u003c\/a\u003e gives its history. People also search \"SR9009 vs SR9011\": SR9011 is the sister compound described in the same 2012 paper, with a similar target and no human data either. We do not stock it.\u003c\/p\u003e\n\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\n\u003cp\u003eCertificates work differently for our own label and for iMuscle. Every Free Muscle-brand batch goes to Janoshik Analytical, an independent laboratory, and the certificate is emailed on request. iMuscle is an outside manufacturer stocked through Muscle Market, so for this product a certificate of analysis appears only when iMuscle provides one for the particular batch on our shelves. We do not pass off a generic PDF without a batch number as a batch certificate. Send us the product name by email and we will forward whatever we hold for the current batch, or tell you directly that nothing is held.\u003c\/p\u003e\n\u003cp\u003eIf an iMuscle certificate is available for this batch, read it in this order:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity\u003c\/strong\u003e: the compound named should be SR9009, not SR9011 or a generic \"Stenabolic\" with no structure. HPLC identifies it by comparing retention time with a reference standard; LC-MS adds a mass, which should fit the 437.9 molecular weight given above.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity\u003c\/strong\u003e: a percentage from HPLC peak areas. It tells you how much of the detected material is SR9009, not how many milligrams a capsule holds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContent per capsule\u003c\/strong\u003e: the measured amount in one capsule, which is the figure to set against the stated 10 mg.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch number\u003c\/strong\u003e: must match the code on the pack you received.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory and test date\u003c\/strong\u003e: name the analyst and show whether the result is recent enough to cover this stock.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor this brand, gaps mean specific things. No certificate means this listing makes no documented claim about identity, purity or content beyond the manufacturer's label. Purity with no content figure confirms the molecule but leaves the 10 mg unverified. A batch number that does not match your pack means the certificate describes different stock, and you should \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e. Our \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003elab tests page\u003c\/a\u003e and the article on \u003ca href=\"\/en-ro\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a COA\u003c\/a\u003e cover the methods in more depth.\u003c\/p\u003e\n\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\n\u003cp\u003eFor athletes, the regulatory point is simple: SR9009 is in section S4 of the WADA Prohibited List and is banned in and out of competition, and under strict liability a positive sample counts regardless of how the substance got there, including through a mislabelled product. The 2016 Ghent study identified eight human liver metabolites of SR9009 so that screens could look for breakdown products as well as the parent compound, and it recommended adding SR9009 to routine screening. When the authors searched 1,511 stored doping control urine results, they found neither SR9009 nor its metabolites in those routine samples.\u003c\/p\u003e\n\u003cp\u003eNo verified study has measured how long SR9009 or its metabolites remain detectable in human urine after exposure. The honest answer for this capsule product is therefore: detectable, window not established. Anyone subject to anti-doping rules should treat it as prohibited.\u003c\/p\u003e\n\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\n\u003cp\u003eNo stability study of SR9009 in capsule form has been published, so the manufacturer's expiry date, where iMuscle prints one, is the only product-specific guide. General laboratory practice for small organic compounds applies: protect from heat, moisture and light.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLeave the capsules in the tub they arrived in: the batch code printed on it is the only link to a certificate.\u003c\/li\u003e\n\u003cli\u003eStore somewhere cool, dry and dark, away from radiators, windowsills and steamy rooms; capsule shells soften in humid air and turn brittle in very dry air.\u003c\/li\u003e\n\u003cli\u003eLog the batch number, date received and date opened.\u003c\/li\u003e\n\u003cli\u003eWear nitrile gloves when handling opened capsules or spilled powder, and clean surfaces afterwards.\u003c\/li\u003e\n\u003cli\u003eSurplus or out-of-date capsules belong in a chemical waste stream, never in household bins or down a drain.\u003c\/li\u003e\n\u003cli\u003eStore on a shelf that children and pets cannot reach, and never in a fridge or cupboard used for food.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eGlossary\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eREV-ERB alpha and beta\u003c\/strong\u003e: nuclear receptors that repress clock and metabolic genes on a daily cycle; SR9009 was designed to activate them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCircadian clock\u003c\/strong\u003e: the internal roughly 24-hour cycle of gene activity found in most cells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAgonist\u003c\/strong\u003e: a molecule that binds a receptor and switches it on.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOff-target effect\u003c\/strong\u003e: an action of a compound that does not go through its intended receptor, as shown for SR9009 in 2019.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSR9011\u003c\/strong\u003e: a closely related REV-ERB agonist described alongside SR9009 in 2012; not stocked here.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePharmacokinetics\u003c\/strong\u003e: the study of what the body does to a substance over time, from uptake to elimination; no human data exist for SR9009.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver microsomes\u003c\/strong\u003e: fractions of liver cells holding drug-metabolising enzymes, used in the test tube to predict metabolites.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolite\u003c\/strong\u003e: a product the body forms by altering a substance, often the target of anti-doping tests.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReference standard\u003c\/strong\u003e: a highly characterised sample of a compound that a laboratory uses to confirm identity and quantity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetention time\u003c\/strong\u003e: the point at which a compound emerges from an HPLC column; a sample and a standard of the same substance should emerge together.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict liability\u003c\/strong\u003e: under anti-doping rules, a finding in a sample stands against the athlete whether or not they knew the substance was there.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAbout iMuscle Stenabolic SR-9009\u003c\/h2\u003e\u003cp\u003eSTENABOLIC is the name on iMuscle's SR9009 pot, printed on a teal label with SR and 9009 underneath; Stenabolic is a trade name for the compound, not a different substance. The front box reads 60 capsules, 10 mg each, and on imuscle.ro the listing reads Stenabolic SR-9009, \"60\/10mg\". No side panel photograph is included, so the front of the pot is the label evidence in this gallery.\u003c\/p\u003e\u003cp\u003eLike S-23, this pot is outside all eight iMuscle stacks we list. SR9009 is not a SARM, although iMuscle sells it within its SARMs range. The brand's About page splits its products into the nine single pots of its standard line, all stocked here, and a combined series that we do not carry. Browse the rest on the \u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eiMuscle brand page\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003eSR9009 activates the REV-ERB receptors that link the body clock to metabolic genes. It came out of academic work at Scripps Research, has been studied in mice and cells but in no published human trial, holds no UK licence, and appears in section S4 of the WADA list. No other SR9009 brand is on our shelves as of October 2026; the \u003ca href=\"\/en-ro\/collections\/sr9009\"\u003eSR9009 collection\u003c\/a\u003e and the \u003ca href=\"\/en-ro\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 research guide\u003c\/a\u003e carry the detail.\u003c\/p\u003e\u003cp\u003eTwo 2021 documents are shown: protocol RN18694 from a Sofia laboratory, which gives iMuscle LTD. as maker and records a single-sample HPLC assay with no lot number, and an English print-out for SR9009 with lot 20210911. iMuscle also states that it tests all its lots at an independent European laboratory. Neither document is matched to current stock, so quote the lot code on your pot when you \u003ca href=\"\/en-ro\/pages\/contact\"\u003econtact us\u003c\/a\u003e; the Janoshik programme is for Free Muscle's own brand, not iMuscle.\u003c\/p\u003e\u003ch2\u003eRelated\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/collections\/sr9009\"\u003eAll brands of SR9009 we stock, compared\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 (Stenabolic): REV-ERB agonist research and the bioavailability problem\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eCardarine\u003c\/a\u003e and the wider \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eSARMs range\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003eBatch testing and certificates of analysis\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice. Summaries of published research describe study findings and are not claims about any product.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eSolt LA, et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature. 2012;485(7396):62-8. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22460951\/\" rel=\"noopener\"\u003ePMID: 22460951\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eWoldt E, et al. Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy. Nat Med. 2013;19(8):1039-46. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23852339\/\" rel=\"noopener\"\u003ePMID: 23852339\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eDierickx P, et al. SR9009 has REV-ERB-independent effects on cell proliferation and metabolism. Proc Natl Acad Sci U S A. 2019;116(25):12147-12152. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31127047\/\" rel=\"noopener\"\u003ePMID: 31127047\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eGeldof L, et al. In Vitro Metabolic Studies of REV-ERB Agonists SR9009 and SR9011. Int J Mol Sci. 2016;17(10):1676. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27706103\/\" rel=\"noopener\"\u003ePMID: 27706103\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eVan Wagoner RM, et al. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004-2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29183075\/\" rel=\"noopener\"\u003ePMID: 29183075\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468980170978,"sku":null,"price":48.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/STENABOLIC_3333x_3eb916f3-0538-401c-8e12-157d57e3440a.jpg?v=1789931416"}],"url":"https:\/\/freemuscle.co.uk\/en-ro\/collections\/sr9009.oembed","provider":"Free Muscle","version":"1.0","type":"link"}