{"title":"Metabolic Support","description":"\u003cp\u003eMetabolic Support is a research-interest grouping of Free Muscle compounds that feature in the literature on metabolism, energy expenditure and body weight: Retatrutide, Cardarine (GW-501516) in 5 mg and 10 mg strengths, Ipamorelin and YK-11. All are supplied as capsules for laboratory research, every Free Muscle batch is assayed by Janoshik Analytical, and the certificate for your batch is available on request. The heading organises the catalogue. It is not a claim that any compound here affects the weight or metabolism of the person reading this page, and nothing here is a weight-loss product.\u003c\/p\u003e\n\u003ch2\u003eWhat this collection covers\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/retatrutide\"\u003eRetatrutide (LY3437943)\u003c\/a\u003e, a peptide agonist at the GIP, GLP-1 and glucagon receptors, in late-stage clinical trials and not approved in any country.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/cardarine\"\u003eCardarine (GW-501516)\u003c\/a\u003e, a PPAR-delta agonist studied for lipid metabolism whose development ended after rodent tumour findings; 5 mg and 10 mg capsules, 60 per pack.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/ipamorelin\"\u003eIpamorelin\u003c\/a\u003e, a pentapeptide growth hormone secretagogue acting on the ghrelin receptor, with limited early clinical data; 60 capsules.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-ro\/collections\/yk-11\"\u003eYK-11\u003c\/a\u003e, a steroidal compound reported in cell studies as a partial androgen receptor agonist with effects on myostatin-related signalling; 10 mg capsules, 60 per pack.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOther brands' metabolic research compounds, including \u003ca href=\"\/en-ro\/collections\/slu-pp-332\"\u003eSLU-PP-332\u003c\/a\u003e and \u003ca href=\"\/en-ro\/collections\/5-amino-1mq\"\u003e5-Amino-1MQ\u003c\/a\u003e, are listed through Muscle Market.\u003c\/p\u003e\n\u003ch2\u003eWhat the published research reports\u003c\/h2\u003e\n\u003cp\u003eRetatrutide has the most substantial human data in this grouping. In a 48-week phase 2 trial of 338 adults with obesity, mean body weight fell by roughly 8 to 24 per cent across dose groups compared with about 2 per cent on placebo. Gastrointestinal adverse events were the most common finding and were dose-related, and phase 3 trials were still under way at the time of writing. Cardarine's human data is limited to short lipid studies, and its rodent safety programme reported tumours. Ipamorelin and YK-11 have little or no controlled human data. None of this is a claim about the products on this page.\u003c\/p\u003e\n\u003ch2\u003eBatch testing and certificates of analysis\u003c\/h2\u003e\n\u003cp\u003eA certificate of analysis states what an independent laboratory identified in a specific batch and the purity it measured. Every Free Muscle batch goes to Janoshik Analytical, and the batch number is printed on the pack. Email us the number and we will send the certificate for that batch. A document without a batch number is not a batch certificate. See \u003ca href=\"\/en-ro\/pages\/lab-tests\"\u003ehow we test\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eLegal status in the UK\u003c\/h2\u003e\n\u003cp\u003eNone of these compounds is a licensed medicine (MHRA) or an authorised food supplement, and none may be sold for human consumption. They are supplied to adults for laboratory research. Retatrutide is an investigational drug with no marketing authorisation anywhere. Under the WADA list, GW-501516 is a prohibited metabolic modulator, ipamorelin a prohibited growth hormone secretagogue, YK-11 a prohibited anabolic agent, and retatrutide falls under non-approved substances.\u003c\/p\u003e\n\u003ch2\u003eDelivery and returns\u003c\/h2\u003e\n\u003cp\u003eFree Muscle is the trading name of FreeMuscle, a business registered in Andorra, with UK operations and dispatch in Scunthorpe. Every order ships free with UK tracking in plain packaging; EU delivery takes 3 to 7 working days. Orders placed before 2pm Monday to Friday are processed the same working day, and unopened items can be returned within 30 days. See \u003ca href=\"\/en-ro\/pages\/shipping\"\u003eshipping\u003c\/a\u003e and \u003ca href=\"\/en-ro\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e. Customers must be 18 or over.\u003c\/p\u003e\n\u003ch2\u003eRelated reading\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/retatrutide-uk-licensing-status-trials-2026\"\u003eRetatrutide in the UK 2026: licensing status and trials\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/sarms-vs-peptides-choosing-by-goal\"\u003eSARMs vs Peptides: Choosing by Goal\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003ePrice per milligram: how to compare SARMs and peptides\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ro\/blogs\/news\/what-is-janoshik-analytical\"\u003eWhat Is Janoshik Analytical? Third-Party Testing Explained\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003eRelated collections: \u003ca href=\"\/en-ro\/collections\/cut\"\u003eCut\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/peptides\"\u003ePeptides\u003c\/a\u003e, \u003ca href=\"\/en-ro\/collections\/sarms\"\u003eSARMs\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eJastreboff AM, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial. N Engl J Med. 2023;389(6):514-526. PMID: 37366315.\u003c\/li\u003e\n\u003c\/ol\u003e","products":[{"product_id":"yk-11-10mg","title":"YK-11 — Myostatin Inhibitor · 10mg · 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eYK-11, 10mg × 60 capsules.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eYK-11 is structurally a steroid, not a true SARM, although it is usually sold alongside them. It is sometimes described as a myostatin-pathway agent; that description rests largely on a single cell-culture study and there is no human data.\u003c\/p\u003e\u003cp\u003eBecause it has a steroidal backbone, androgenic and liver effects cannot be ruled out. It is \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e and is prohibited in sport by WADA.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request. We do not publish dosing schedules, cycle lengths or post-cycle protocols for human use.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":46857393144034,"sku":"10000012","price":49.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/yk_11_10mg_60_capsules.jpg?v=1766262356"},{"product_id":"cardarine-5mg-free-muscle","title":"Cardarine GW-501516 — 5mg · 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eCardarine (GW-501516), 5mg × 60 capsules.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eCardarine is a PPAR-delta agonist. Clinical development was abandoned after cancers were found at multiple organ sites in animal studies. That is the reason it is not a medicine, and we would rather you knew it before buying than after.\u003c\/p\u003e\u003cp\u003eThere are no completed human efficacy trials. It is \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e and is on the WADA Prohibited List, where it is detectable.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request. We do not publish dosing schedules or cycle lengths for human use.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":46857402613986,"sku":"10000011","price":29.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/openart-image_RQOkrWwu_1760826716832_raw_1.jpg?v=1766262406"},{"product_id":"cardarine-gw-501516-10mg-free-muscle-60-capsules","title":"Cardarine GW-501516 — 10mg · 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eCardarine (GW-501516), 10mg × 60 capsules.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eCardarine is a PPAR-delta agonist. Clinical development was abandoned after cancers were found at multiple organ sites in animal studies. That is the reason it is not a medicine, and we would rather you knew it before buying than after.\u003c\/p\u003e\u003cp\u003eThere are no completed human efficacy trials. It is \u003cstrong\u003enot authorised for human consumption in the UK or EU\u003c\/strong\u003e and is on the WADA Prohibited List, where it is detectable.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request. We do not publish dosing schedules or cycle lengths for human use.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":46857405432034,"sku":"10000010","price":39.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/openart-image_Oef-QDdF_1760826110182_raw_e832e96d-2ef9-42b1-a8b2-c1f787319c72.jpg?v=1766262431"},{"product_id":"retatrutide","title":"Retatrutide — Research Peptide","description":"\u003cp\u003e\u003cstrong\u003eRetatrutide (LY3437943), research peptide.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eRetatrutide is an investigational triple agonist at the GIP, GLP-1 and glucagon receptors. \u003cstrong\u003eIt is not approved as a medicine by any regulator in the world\u003c\/strong\u003e, not the MHRA, not the EMA, not the FDA. Phase 2 obesity results were published in 2023; Phase 3 trials are still running. Nothing is finished.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eThe published trials used subcutaneous injection. This product is a capsule\u003c\/strong\u003e, and peptides taken by mouth are largely broken down in the gut. We are not going to claim an oral capsule reproduces trial results.\u003c\/p\u003e\u003cp\u003eTrial participants reported nausea, vomiting, diarrhoea and constipation, with dose escalation managed by clinicians throughout.\u003c\/p\u003e\u003cp\u003eWeight-management treatment is a matter for a doctor. There are licensed medicines with approved safety profiles and clinical supervision. This is not one of them and we are not selling it as one.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":47171527639266,"sku":"28876573","price":89.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/IMG-2901.jpg?v=1766262736"},{"product_id":"ipamorelin","title":"Ipamorelin — Research Peptide","description":"\u003cp\u003e\u003cstrong\u003eIpamorelin, 60 capsules.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIpamorelin is a selective agonist at the ghrelin (GHS-R1a) receptor. It was studied in early clinical work and development was discontinued. Effects on glucose regulation and long-term safety are not established.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIt is a capsule, and peptides taken by mouth are largely broken down by digestive enzymes before absorption.\u003c\/strong\u003e That is why clinical work on this class uses injection. We are not going to claim a capsule matches that.\u003c\/p\u003e\u003cp\u003eIt is \u003cstrong\u003enot authorised as a medicine or a food supplement in the UK or EU\u003c\/strong\u003e, and growth hormone secretagogues are on the WADA Prohibited List.\u003c\/p\u003e\u003cp\u003eIdentity and purity are verified per batch by Janoshik Analytical, an independent laboratory. Certificate of Analysis available on request.\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eResearch compounds sold by Free Muscle are supplied for laboratory research use only and are not for human consumption. They are not authorised as medicines by the MHRA, EMA or FDA, are not food supplements, and are sold only to adults aged 18 or over. Nothing on this page is medical or dosing advice.\u003c\/small\u003e\u003c\/p\u003e","brand":"FreeMuscle","offers":[{"title":"Default Title","offer_id":47171533635810,"sku":"25506679","price":29.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/IMG-2904.jpg?v=1766262743"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/collections\/IMG-3853.jpg?v=1790530356","url":"https:\/\/freemuscle.co.uk\/en-ro\/collections\/weight-loss.oembed","provider":"Free Muscle","version":"1.0","type":"link"}