{"product_id":"imuscle-cardarine-gw501516-60-10mg","title":"iMuscle Cardarine GW-501516 — 60 caps, 10mg","description":"\u003cp\u003e\u003cstrong\u003eiMuscle Cardarine GW-501516, 60 caps, 10mg\u003c\/strong\u003e is an iMuscle listing of Cardarine, labelled at 10 mg per capsule, 60 capsules per pack, 600 mg in total. It is supplied through the Muscle Market range for laboratory research only, is not for human consumption, and is sold to adults aged 18 and over. Below: what the published research reports, including why development was abandoned, the UK legal position, and how batch certificates are handled for iMuscle products.\u003c\/p\u003e\n\u003ch2\u003eAbout Cardarine\u003c\/h2\u003e\n\u003cp\u003eGW-501516 is the development code; Cardarine, GW501516, GW1516 and endurobol are the other names under which the same molecule is sold. Pharmacologically it is a synthetic PPAR-delta agonist. PPAR-delta is a nuclear receptor, and in skeletal muscle it controls genes that govern how fatty acids are oxidised for energy. GlaxoSmithKline and Ligand took the compound forward as a possible treatment for lipid disorders. Sellers often place it next to SARMs, but it never touches the androgen receptor, and despite occasional searches for \"cardarine peptide\" it is a small molecule of about 454 g\/mol rather than an amino acid chain.\u003c\/p\u003e\n\u003ch3\u003eWhat the published research reports\u003c\/h3\u003e\n\u003cp\u003eIn a 2008 study in mice, GW-501516 combined with treadmill training increased oxidative muscle fibres and running endurance more than training alone, and the authors described PPAR-delta and AMPK agonists as exercise mimetics; in the same paper it was AICAR, a different compound, that raised endurance in untrained mice (Narkar et al., 2008). A GlaxoSmithKline trial published in 2012, in 268 people with low HDL cholesterol, reported that over twelve weeks HDL rose while LDL cholesterol and triglycerides fell from baseline; the trial was short and not designed to assess long-term safety (Olson et al., 2012). Anti-doping researchers later summarised the clinical programme as having reached phase II trials in dyslipidaemia and metabolic syndrome (Thevis et al., 2010).\u003c\/p\u003e\n\u003cp\u003eDevelopment was abandoned in 2007 after two-year carcinogenicity studies in rats and mice found tumours in multiple organs. Those toxicology results were presented at a conference and are not indexed on PubMed, so they are not cited here, but they are the most important fact about this compound. No later human trial has been completed and Cardarine has never been approved as a medicine anywhere. Nothing above is a claim about this product.\u003c\/p\u003e\n\u003ch3\u003eChemical identity\u003c\/h3\u003e\n\u003cp\u003eThese PubChem identifiers describe the molecule a batch certificate for this pack should name.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystematic name\u003c\/strong\u003e: 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number\u003c\/strong\u003e: 317318-70-0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormula and molecular weight\u003c\/strong\u003e: C21H18F3NO3S2, 453.5 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInChIKey\u003c\/strong\u003e: YDBLKRPLXZNVNB-UHFFFAOYSA-N\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePubChem CID\u003c\/strong\u003e: 9803963\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eThis listing\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eManufacturer: iMuscle\u003c\/li\u003e\n\u003cli\u003eCompound: Cardarine (GW-501516)\u003c\/li\u003e\n\u003cli\u003eForm: Capsules\u003c\/li\u003e\n\u003cli\u003ePack size: 60 capsules\u003c\/li\u003e\n\u003cli\u003eStrength: 10 mg per capsule, as stated by the manufacturer\u003c\/li\u003e\n\u003cli\u003eTotal in pack: 600 mg (10 mg x 60 capsules)\u003c\/li\u003e\n\u003cli\u003eBatch certificate of analysis: shown where iMuscle supplies one for the batch we hold\u003c\/li\u003e\n\u003cli\u003eIntended use: laboratory research only, not for human consumption, adults aged 18 and over\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe 10 mg figure is iMuscle's label claim. Only an assay of the batch confirms it. To compare this pack with other Cardarine listings, work from the total milligrams per pack and the cost per milligram, as set out in \u003ca href=\"\/blogs\/news\/price-per-mg-compare-sarms-peptides\"\u003eprice per milligram\u003c\/a\u003e, and then check what certificate each seller holds.\u003c\/p\u003e\n\u003ch2\u003eCardarine in the UK: buying, legal status and what to check\u003c\/h2\u003e\n\u003cp\u003eSearches such as \"cardarine UK\", \"cardarine UK legal\", \"cardarine UK buy\" and \"cardarine for sale\" come down to two questions: may Cardarine be bought here at all, and how can a buyer tell a listing that can be checked from one that asks to be trusted.\u003c\/p\u003e\n\u003ch3\u003eThe legal position\u003c\/h3\u003e\n\u003cp\u003eCardarine is not a licensed medicine in the UK, has not been assessed by the MHRA, and is not an authorised food supplement, so it cannot lawfully be sold for people to swallow. It is not a controlled drug under the Misuse of Drugs Act 1971. Free Muscle sells it to adults aged 18 and over for laboratory research only, and gives no instructions for use. GW-501516 is named on the WADA Prohibited List under section S4 (hormone and metabolic modulators) as a PPAR-delta agonist and is prohibited at all times in sport. WADA issued a specific warning about it in 2013. Buyers are responsible for the rules that apply to them, including import rules for EU orders. Our \u003ca href=\"\/blogs\/news\/what-are-sarms-the-2026-research-guide\"\u003eresearch guide\u003c\/a\u003e covers the wider legal picture for compounds sold alongside SARMs.\u003c\/p\u003e\n\u003ch3\u003eWhat a checkable UK listing shows\u003c\/h3\u003e\n\u003cp\u003eMany sites file Cardarine under SARMs, but the category label proves nothing. What counts is a short list of verifiable facts, set against this listing below.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eWhat to look for\u003c\/th\u003e\n\u003cth\u003eThis listing\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eA stated strength, a unit count and a pack total that agree\u003c\/td\u003e\n\u003ctd\u003e10 mg per capsule, 60 capsules, 600 mg per pack\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA named manufacturer and a named seller\u003c\/td\u003e\n\u003ctd\u003eMade by iMuscle; sold by FreeMuscle LTD, a UK company based in Scunthorpe\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA certificate tied to the batch number on the pot\u003c\/td\u003e\n\u003ctd\u003eThe manufacturer's certificate, where iMuscle supplies one for the batch we hold\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eResearch-only terms with no usage directions\u003c\/td\u003e\n\u003ctd\u003eResearch use only, 18+, no amounts, schedules or result claims\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTracked delivery and discreet packaging\u003c\/td\u003e\n\u003ctd\u003eFree tracked UK delivery in plain packaging; orders placed before 2pm Monday to Friday processed the same working day; EU delivery in 3-7 working days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eA returns policy\u003c\/td\u003e\n\u003ctd\u003e30-day returns on unopened items, see \u003ca href=\"\/pages\/shipping\"\u003edelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003eguarantee\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eA listing that promises results, quotes user reviews as evidence or shows before-and-after pictures is advertising a use, which a research supplier cannot lawfully do. The fuller supplier checklist is in \u003ca href=\"\/blogs\/news\/how-to-choose-a-sarms-supplier-uk-checklist\"\u003ehow to choose a SARMs supplier in the UK\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eCapsules compared with other forms\u003c\/h2\u003e\n\u003cp\u003eCardarine appears in three physical forms: filled capsules like this pack, liquids sold by concentration, and loose powder sold by weight. The molecule is the same; what differs is where the quantity per unit is fixed and how easily it can be verified. No published study compares these formats for GW-501516.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsules.\u003c\/strong\u003e The 10 mg per capsule is fixed when powder is blended and filled at manufacture, so an assay can measure it directly and the figure cannot drift once the pot is sealed. The weak point is uniformity between individual capsules, which a pooled assay averages out.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquids.\u003c\/strong\u003e Accuracy depends on the concentration being correct and on how precisely a volume is measured. Carrier solvents can evaporate from a bottle that is opened repeatedly, raising the concentration of what is left, and cold storage can cause the compound to crystallise out.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePowder.\u003c\/strong\u003e Accuracy rests entirely on the balance and technique of the laboratory weighing it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBecause Cardarine is a small molecule and not a peptide, the argument that digestive enzymes break down peptides taken by mouth does not apply to it in the same way (see \u003ca href=\"\/blogs\/news\/do-oral-peptides-work\"\u003edo oral peptides work\u003c\/a\u003e). On stability, a dry powder sealed in a capsule is kept away from water and solvents, where chemical breakdown generally proceeds fastest, but we know of no published shelf-life study for any Cardarine format.\u003c\/p\u003e\n\u003ch2\u003eCardarine compared with SR9009\u003c\/h2\u003e\n\u003cp\u003e\"Stenabolic vs cardarine\" is the comparison searched most often for this compound, largely because both are sold under metabolic or endurance headings. Pharmacologically they have little in common beyond being synthetic ligands of nuclear receptors.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eCardarine (this product)\u003c\/th\u003e\n\u003cth\u003eSR9009 (stenabolic)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTarget\u003c\/td\u003e\n\u003ctd\u003ePPAR-delta, a fatty acid sensing receptor\u003c\/td\u003e\n\u003ctd\u003eREV-ERB alpha and beta, repressors in the body clock machinery\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrigin\u003c\/td\u003e\n\u003ctd\u003eGlaxoSmithKline and Ligand, lipid disorders programme\u003c\/td\u003e\n\u003ctd\u003eAcademic laboratory at the Scripps Research Institute\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormula and CAS\u003c\/td\u003e\n\u003ctd\u003eC21H18F3NO3S2, 317318-70-0\u003c\/td\u003e\n\u003ctd\u003eC20H24ClN3O4S, 1379686-30-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHuman data\u003c\/td\u003e\n\u003ctd\u003eShort phase II lipid trials\u003c\/td\u003e\n\u003ctd\u003eNo published human trial\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKey limiting finding\u003c\/td\u003e\n\u003ctd\u003eTumours in two-year rodent studies; development stopped in 2007\u003c\/td\u003e\n\u003ctd\u003eEvidence confined to cells and animals\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLicensed as a medicine\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003ctd\u003eNowhere\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWADA\u003c\/td\u003e\n\u003ctd\u003eS4, metabolic modulator, prohibited at all times\u003c\/td\u003e\n\u003ctd\u003eS4, metabolic modulator, prohibited at all times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eSR9009 was first described in 2012, when a Scripps group reported that synthetic REV-ERB agonists altered circadian behaviour and the daily pattern of clock and metabolic gene expression in mice, raised energy expenditure, and reduced fat mass in diet-induced obese mice (Solt et al., 2012). That is a mouse study; no human trial of SR9009 has been published, so its record is shorter than Cardarine's but also lacks Cardarine's two-year toxicology data, which is absence of information rather than reassurance. Cardarine, by contrast, has human lipid data and a carcinogenicity finding that ended its development.\u003c\/p\u003e\n\u003cp\u003eNeither compound is interchangeable with the other, neither is licensed, and both are sold here for laboratory research only. SR9009 listings, including \u003ca href=\"\/products\/imuscle-stenabolic-sr-9009-60-10mg\"\u003eiMuscle Stenabolic SR-9009\u003c\/a\u003e, are compared in the \u003ca href=\"\/collections\/sr9009\"\u003eSR9009 (Stenabolic) collection\u003c\/a\u003e, and the background is in \u003ca href=\"\/blogs\/news\/sr9009-stenabolic-research-guide\"\u003eSR9009 (Stenabolic): the research guide\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eReading the certificate of analysis for this product\u003c\/h2\u003e\n\u003cp\u003eThe Janoshik Analytical programme that assays every Free Muscle-brand batch, with certificates emailed on request, does not extend to this pack, because iMuscle manufactures it. Any certificate here is iMuscle's own, and we display one only when iMuscle has supplied it for the exact batch on our shelves. We will not pass off an undated or batch-free PDF as a certificate. \u003ca href=\"\/pages\/contact\"\u003eContact us\u003c\/a\u003e with the product name and we will either send the document for current stock or tell you that none exists. Where one is available, these are the lines worth reading.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat was tested.\u003c\/strong\u003e Look for GW-501516 or Cardarine by name, and preferably CAS 317318-70-0. A heading such as \"PPAR agonist\" or \"SARM\" could describe dozens of substances.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow identity was shown.\u003c\/strong\u003e A matching retention time on HPLC against a reference standard is the basic check. Where LC-MS was run, the measured mass ought to fit C21H18F3NO3S2 at 453.5 g\/mol, which is harder to fake or misread.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity figure.\u003c\/strong\u003e Normally a percentage of total peak area on the chromatogram. A high number means few contaminants were seen; it does not reveal the milligram content of a capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMeasured milligrams.\u003c\/strong\u003e An assay result in mg per capsule is what tests iMuscle's 10 mg claim. Without it, the 600 mg pack total rests on the label alone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLot and date.\u003c\/strong\u003e Compare the lot on the report with the lot on the pot; a mismatch means the report describes other stock. The date tells you how long ago the sample was analysed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIssuing laboratory.\u003c\/strong\u003e A named laboratory can be asked to confirm that the report is genuine.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eA missing field is information in itself: whatever the certificate does not measure remains a label claim. Our \u003ca href=\"\/pages\/lab-tests\"\u003elab tests page\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/how-to-read-a-certificate-of-analysis\"\u003ehow to read a certificate of analysis\u003c\/a\u003e explain the documents in more detail.\u003c\/p\u003e\n\u003ch2\u003eDetection, sport and testing\u003c\/h2\u003e\n\u003cp\u003eGW-501516 has been on the WADA Prohibited List since January 2009, when it was first classed as a gene doping agent; it now sits in section S4 among the metabolic modulators and is prohibited in and out of competition (Thevis et al., 2010). Anti-doping rules apply strict liability, so an athlete is responsible for any prohibited substance in a sample regardless of how it got there, including through a mislabelled product.\u003c\/p\u003e\n\u003cp\u003eTesting does not rely on finding the unchanged compound. The Cologne anti-doping laboratory synthesised the two main urinary metabolites, a sulfoxide and a sulfone formed by oxidation of the sulphur atom, confirmed their structures by high-resolution mass spectrometry and NMR, and validated a routine screening method with a reported limit of detection of 0.1 ng\/ml in urine (Thevis et al., 2010). Numerous sanctions have followed.\u003c\/p\u003e\n\u003cp\u003eWe know of no verified published figure for how long Cardarine or its metabolites remain detectable after exposure, so the accurate statement for this product is: detectable, window not established. The lack of a published window is not evidence that the window is short.\u003c\/p\u003e\n\u003ch2\u003eStorage, stability and handling\u003c\/h2\u003e\n\u003cp\u003eNo published stability study covers Cardarine capsules, so the expiry or best-before date printed by iMuscle is the working limit, and any certificate describes the batch on its test date rather than today.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the original pot.\u003c\/strong\u003e The lot number on the label is what links the capsules to a certificate; capsules moved to another container lose that link.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCool, dry and dark.\u003c\/strong\u003e Store below room temperature where possible, away from radiators and sunny windowsills, and away from bathroom or kitchen humidity, which softens gelatine shells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep a record.\u003c\/strong\u003e Write down when the seal was broken, and give any aliquot sent for analysis its own label carrying the lot number.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCheck condition.\u003c\/strong\u003e If shells have cracked, turned sticky or changed colour, the contents may have changed too; quarantine them and send us the lot number.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory practice.\u003c\/strong\u003e Gloves for any opened capsule, a work area separate from food and drink, storage beyond the reach of children and pets, and disposal through the chemical waste route your local rules set out.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eGlossary\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePPAR-delta\u003c\/strong\u003e: one of three peroxisome proliferator-activated receptors (alpha, gamma and delta); the delta form is widespread in muscle and is the receptor Cardarine binds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eREV-ERB\u003c\/strong\u003e: a pair of nuclear receptors in the circadian clock machinery; the target of SR9009.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExercise mimetic\u003c\/strong\u003e: the description Narkar and colleagues applied in 2008, based on changes in mouse muscle, not on any human finding.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHDL cholesterol\u003c\/strong\u003e: high-density lipoprotein cholesterol, one of the blood lipid measures reported in the human trials.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCarcinogenicity study\u003c\/strong\u003e: a long-term animal study, usually two years in rodents, designed to detect tumour formation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhase II trial\u003c\/strong\u003e: an early human study testing effects on a disease marker in a limited number of participants.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHPLC\u003c\/strong\u003e: a technique that pumps a dissolved sample through a packed column so its components emerge at different times and can be measured.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLC-MS\u003c\/strong\u003e: liquid chromatography coupled to mass spectrometry, which adds a molecular mass to the identity check.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSulfoxide and sulfone\u003c\/strong\u003e: the oxidised forms of GW-501516 found in urine, which anti-doping laboratories screen for.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLimit of detection\u003c\/strong\u003e: the lowest concentration an analytical method can reliably distinguish from zero.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRelated\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/cardarine\"\u003eAll brands of Cardarine we stock, compared\u003c\/a\u003e, including \u003ca href=\"\/products\/thoroughbred-labs-gw501516\"\u003eThoroughbred Labs GW-501516\u003c\/a\u003e and our own \u003ca href=\"\/products\/cardarine-gw-501516-10mg-free-muscle-60-capsules\"\u003eFree Muscle Cardarine 10mg\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/brand-imuscle\"\u003eAll iMuscle products\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/cardarine-gw-501516-what-happened-in-development\"\u003eCardarine (GW-501516): why development stopped and what the data show\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/collections\/sr9009\"\u003eSR9009 (Stenabolic)\u003c\/a\u003e and \u003ca href=\"\/collections\/weight-loss\"\u003emetabolic support\u003c\/a\u003e collections\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/lab-tests\"\u003eBatch testing and certificates of analysis\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/pages\/shipping\"\u003eDelivery\u003c\/a\u003e and \u003ca href=\"\/pages\/guarantee\"\u003ereturns\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is supplied for laboratory research use only. It has not been evaluated by the MHRA, EMA or FDA. It is not a medicine, not a food supplement and not for human consumption. Sold only to adults aged 18 and over. Nothing on this page is medical, dosing or usage advice, and descriptions of published studies are not claims about this product.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eNarkar VA, et al. AMPK and PPARdelta agonists are exercise mimetics. Cell. 2008;134(3):405-15. PMID: 18674809.\u003c\/li\u003e\n\u003cli\u003eOlson EJ, et al. Lipid effects of peroxisome proliferator-activated receptor-delta agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Arterioscler Thromb Vasc Biol. 2012;32(9):2289-94. PMID: 22814748.\u003c\/li\u003e\n\u003cli\u003eThevis M, et al. Characterization of two major urinary metabolites of the PPARdelta-agonist GW1516 and implementation of the drug in routine doping controls. Anal Bioanal Chem. 2010;396(7):2479-91. PMID: 19946680.\u003c\/li\u003e\n\u003cli\u003eSolt LA, et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature. 2012;485(7396):62-8. PMID: 22460951.\u003c\/li\u003e\n\u003c\/ol\u003e\n","brand":"iMuscle","offers":[{"title":"Default Title","offer_id":48468978958562,"sku":null,"price":49.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/3499\/5426\/files\/CARDARINE2_720x_d6eeb76e-e12e-4d4e-8613-f1d8572b8197.jpg?v=1789931398","url":"https:\/\/freemuscle.co.uk\/products\/imuscle-cardarine-gw501516-60-10mg","provider":"Free Muscle","version":"1.0","type":"link"}